CN101983327A - 生物样本的反复染色 - Google Patents

生物样本的反复染色 Download PDF

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Publication number
CN101983327A
CN101983327A CN200980112550XA CN200980112550A CN101983327A CN 101983327 A CN101983327 A CN 101983327A CN 200980112550X A CN200980112550X A CN 200980112550XA CN 200980112550 A CN200980112550 A CN 200980112550A CN 101983327 A CN101983327 A CN 101983327A
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China
Prior art keywords
chute
decolorant
activation
premixed
volume capacity
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CN200980112550XA
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English (en)
Chinese (zh)
Inventor
谢军
F·金蒂
R·J·菲尔金斯
M·C·蒙塔尔托
A·苏德
J·B·福廷
田维诚
M·J·格德斯
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General Electric Co
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General Electric Co
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Publication of CN101983327A publication Critical patent/CN101983327A/zh
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31Apparatus therefor
    • G01N1/312Apparatus therefor for samples mounted on planar substrates

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Microscoopes, Condenser (AREA)
CN200980112550XA 2008-04-02 2009-04-01 生物样本的反复染色 Pending CN101983327A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/061,044 US20090253163A1 (en) 2008-04-02 2008-04-02 Iterative staining of biological samples
US12/061044 2008-04-02
PCT/US2009/039052 WO2009124099A1 (en) 2008-04-02 2009-04-01 Iterative staining of biological samples

Publications (1)

Publication Number Publication Date
CN101983327A true CN101983327A (zh) 2011-03-02

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN200980112550XA Pending CN101983327A (zh) 2008-04-02 2009-04-01 生物样本的反复染色

Country Status (5)

Country Link
US (2) US20090253163A1 (https=)
EP (1) EP2260283A1 (https=)
JP (1) JP5518834B2 (https=)
CN (1) CN101983327A (https=)
WO (1) WO2009124099A1 (https=)

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CN103743611A (zh) * 2014-01-16 2014-04-23 西南大学 一种烟草腺毛及腺毛分泌物的染色液和染色方法
CN104583753A (zh) * 2012-06-29 2015-04-29 通用电气公司 用于生物样本的处理和成像的系统和方法
CN112113822A (zh) * 2019-06-21 2020-12-22 深圳迈瑞生物医疗电子股份有限公司 生物样本染色装置、推片染色机及生物样本染色方法

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EP3013983B1 (en) 2013-06-25 2023-02-15 Prognosys Biosciences, Inc. Spatially encoded biological assays using a microfluidic device
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WO2015191978A1 (en) * 2014-06-12 2015-12-17 University Of Notre Dame Microfluidic devices, systems, and methods for imaging tissue samples
US10774374B2 (en) 2015-04-10 2020-09-15 Spatial Transcriptomics AB and Illumina, Inc. Spatially distinguished, multiplex nucleic acid analysis of biological specimens
JP6841609B2 (ja) 2015-07-10 2021-03-10 3スキャン インコーポレイテッド 組織学的染色の空間的多重化
EP3332253A1 (en) * 2015-08-06 2018-06-13 Lasergen, Inc. Antigen detection using photocleavable labels
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US11446671B2 (en) 2016-03-29 2022-09-20 Leica Microsystems Cms Gmbh Self-contained slide processing unit for biological specimens
CN110637222A (zh) 2017-05-26 2019-12-31 文塔纳医疗系统公司 非接触式、在载玻片上的流体混合
WO2020247409A1 (en) * 2019-06-02 2020-12-10 Essenlix Corporation Fast staining of biomaterials enhanced by image processing and artificial intelligence
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US12157124B2 (en) 2019-11-06 2024-12-03 10X Genomics, Inc. Imaging system hardware
US12405264B2 (en) 2020-01-17 2025-09-02 10X Genomics, Inc. Electrophoretic system and method for analyte capture
CN116134308B (zh) 2020-05-19 2025-05-27 10X基因组学有限公司 电泳盒和仪器
EP4153775B1 (en) 2020-05-22 2024-07-24 10X Genomics, Inc. Simultaneous spatio-temporal measurement of gene expression and cellular activity
US12031177B1 (en) 2020-06-04 2024-07-09 10X Genomics, Inc. Methods of enhancing spatial resolution of transcripts
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US20220062898A1 (en) 2020-08-28 2022-03-03 Leica Microsystems Cms Gmbh Microfluidic Device for Image Multiplexing
EP4491742B1 (en) 2020-09-18 2026-03-04 10X Genomics, Inc. Sample handling apparatus and image registration methods
WO2022178267A2 (en) 2021-02-19 2022-08-25 10X Genomics, Inc. Modular assay support devices
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104583753A (zh) * 2012-06-29 2015-04-29 通用电气公司 用于生物样本的处理和成像的系统和方法
CN104583753B (zh) * 2012-06-29 2017-12-01 通用电气公司 用于生物样本的处理和成像的系统和方法
CN103743611A (zh) * 2014-01-16 2014-04-23 西南大学 一种烟草腺毛及腺毛分泌物的染色液和染色方法
CN112113822A (zh) * 2019-06-21 2020-12-22 深圳迈瑞生物医疗电子股份有限公司 生物样本染色装置、推片染色机及生物样本染色方法

Also Published As

Publication number Publication date
EP2260283A1 (en) 2010-12-15
US20090253163A1 (en) 2009-10-08
WO2009124099A1 (en) 2009-10-08
US20120135449A1 (en) 2012-05-31
JP5518834B2 (ja) 2014-06-11
JP2011518320A (ja) 2011-06-23

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Application publication date: 20110302