CN101978248A - 具有整合微流化生物标记物光学检测阵列装置的发现工具和使用方法 - Google Patents

具有整合微流化生物标记物光学检测阵列装置的发现工具和使用方法 Download PDF

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CN101978248A
CN101978248A CN2008801245973A CN200880124597A CN101978248A CN 101978248 A CN101978248 A CN 101978248A CN 2008801245973 A CN2008801245973 A CN 2008801245973A CN 200880124597 A CN200880124597 A CN 200880124597A CN 101978248 A CN101978248 A CN 101978248A
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sample
zymolyte
protein
substrate
extension
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P·沈
L·蒋
K·蒋
陈仲中
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Dynamic Throughput Inc
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Dynamic Throughput Inc
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Priority claimed from US11/970,451 external-priority patent/US7952705B2/en
Priority claimed from US12/191,812 external-priority patent/US20090097022A1/en
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
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    • B01L2300/00—Additional constructional details
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    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
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    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N2021/651—Cuvettes therefore

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  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Optical Measuring Cells (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN2008801245973A 2008-01-07 2008-10-31 具有整合微流化生物标记物光学检测阵列装置的发现工具和使用方法 Pending CN101978248A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11/970,451 US7952705B2 (en) 2007-08-24 2008-01-07 Integrated microfluidic optical device for sub-micro liter liquid sample microspectroscopy
US11/970,451 2008-01-07
US12/191,812 2008-08-14
US12/191,812 US20090097022A1 (en) 2007-08-24 2008-08-14 Discovery tool with integrated microfluidic biomarker optical detection array device and methods for use
PCT/US2008/012369 WO2009088408A1 (fr) 2008-01-07 2008-10-31 Outil de découverte avec dispositif de réseau de détection optique de biomarqueurs microfluidique et intégré, et procédés d'utilisation

Publications (1)

Publication Number Publication Date
CN101978248A true CN101978248A (zh) 2011-02-16

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CN2008801245973A Pending CN101978248A (zh) 2008-01-07 2008-10-31 具有整合微流化生物标记物光学检测阵列装置的发现工具和使用方法

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EP (1) EP2229578A4 (fr)
JP (1) JP2011511933A (fr)
CN (1) CN101978248A (fr)
AU (1) AU2008347152A1 (fr)
CA (1) CA2710828A1 (fr)
WO (1) WO2009088408A1 (fr)

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CN103718038A (zh) * 2011-05-29 2014-04-09 韩国化学研究院 高速的基于拉曼分析的多药物高速筛选装置
WO2015010545A1 (fr) * 2013-07-25 2015-01-29 中国科学院苏州纳米技术与纳米仿生研究所 Capteur térahertz haute sensibilité à canal microfluidique et son procédé de fabrication
CN104880391A (zh) * 2015-06-23 2015-09-02 好来化工(中山)有限公司 用于检测唾液中颗粒物质的装置
CN105100560A (zh) * 2014-05-21 2015-11-25 东和株式会社 电子零件封装体侧面摄影装置
CN105143858A (zh) * 2013-03-14 2015-12-09 惠普发展公司，有限责任合伙企业 用来检测物质的器件和产生这样的器件的方法
CN106574231A (zh) * 2014-05-07 2017-04-19 原子能和替代能源委员会 缺少功能性dyrkp‑1基因的绿色微藻在增加原料产量中的应用
CN107144620A (zh) * 2017-03-31 2017-09-08 兰州百源基因技术有限公司 糖尿病肾病检测标志物
CN107179309A (zh) * 2017-05-22 2017-09-19 厦门大学 一种精氨酸激酶的检测方法
CN108291867A (zh) * 2015-07-01 2018-07-17 曼塔仪器股份有限公司 用于液体中纳米颗粒的显微观察的专用试管组件和方法
CN108982826A (zh) * 2018-09-28 2018-12-11 广东工业大学 一种斑马鱼检测纳米颗粒对胚胎毒性的测试装置和测试方法
CN110327996A (zh) * 2019-09-03 2019-10-15 中国科学院上海高等研究院 微流控芯片、微流控系统及红外微流控分析方法
TWI695151B (zh) * 2012-11-30 2020-06-01 美商凱特伊夫公司 氣體包體系統
CN112626200A (zh) * 2021-01-12 2021-04-09 复旦大学附属妇产科医院 血清微囊泡-天冬酰胺内肽酶假基因1在子宫内膜异位症诊断及复发预测中的用途
CN117844932A (zh) * 2024-03-07 2024-04-09 珠海圣美生物诊断技术有限公司 人类3号和10号染色体异常细胞检测试剂盒及其制备方法

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JPWO2023106372A1 (fr) * 2021-12-08 2023-06-15

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Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103718038A (zh) * 2011-05-29 2014-04-09 韩国化学研究院 高速的基于拉曼分析的多药物高速筛选装置
TWI695151B (zh) * 2012-11-30 2020-06-01 美商凱特伊夫公司 氣體包體系統
CN105143858A (zh) * 2013-03-14 2015-12-09 惠普发展公司，有限责任合伙企业 用来检测物质的器件和产生这样的器件的方法
US9778175B2 (en) 2013-07-25 2017-10-03 Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences High-sensitivity terahertz micro-fluidic channel sensor and preparation method thereof
WO2015010545A1 (fr) * 2013-07-25 2015-01-29 中国科学院苏州纳米技术与纳米仿生研究所 Capteur térahertz haute sensibilité à canal microfluidique et son procédé de fabrication
CN106574231A (zh) * 2014-05-07 2017-04-19 原子能和替代能源委员会 缺少功能性dyrkp‑1基因的绿色微藻在增加原料产量中的应用
CN106574231B (zh) * 2014-05-07 2020-12-22 原子能和替代能源委员会 缺少功能性dyrkp-1基因的绿色微藻在增加原料产量中的应用
CN105100560A (zh) * 2014-05-21 2015-11-25 东和株式会社 电子零件封装体侧面摄影装置
CN104880391A (zh) * 2015-06-23 2015-09-02 好来化工(中山)有限公司 用于检测唾液中颗粒物质的装置
CN108291867A (zh) * 2015-07-01 2018-07-17 曼塔仪器股份有限公司 用于液体中纳米颗粒的显微观察的专用试管组件和方法
CN107144620A (zh) * 2017-03-31 2017-09-08 兰州百源基因技术有限公司 糖尿病肾病检测标志物
CN107179309A (zh) * 2017-05-22 2017-09-19 厦门大学 一种精氨酸激酶的检测方法
CN107179309B (zh) * 2017-05-22 2019-06-07 厦门大学 一种精氨酸激酶的检测方法
CN108982826A (zh) * 2018-09-28 2018-12-11 广东工业大学 一种斑马鱼检测纳米颗粒对胚胎毒性的测试装置和测试方法
CN108982826B (zh) * 2018-09-28 2024-03-26 广东工业大学 一种斑马鱼检测纳米颗粒对胚胎毒性的测试装置和测试方法
CN110327996A (zh) * 2019-09-03 2019-10-15 中国科学院上海高等研究院 微流控芯片、微流控系统及红外微流控分析方法
CN112626200A (zh) * 2021-01-12 2021-04-09 复旦大学附属妇产科医院 血清微囊泡-天冬酰胺内肽酶假基因1在子宫内膜异位症诊断及复发预测中的用途
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