CN101955991B - 白血病相关的融合基因的联合检测方法及诊断试剂盒 - Google Patents

白血病相关的融合基因的联合检测方法及诊断试剂盒 Download PDF

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CN101955991B
CN101955991B CN201010137451.1A CN201010137451A CN101955991B CN 101955991 B CN101955991 B CN 101955991B CN 201010137451 A CN201010137451 A CN 201010137451A CN 101955991 B CN101955991 B CN 101955991B
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leukemia
seq
fusion gene
gene
primer
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Chinese (zh)
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CN101955991A (zh
Inventor
邵棠
徐春雷
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JIANGSU MAIDI BIOTECHNOLOGY CO Ltd
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JIANGSU MAIDI BIOTECHNOLOGY CO Ltd
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Priority to PCT/CN2011/072139 priority patent/WO2011120398A1/fr
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57426—Specifically defined cancers leukemia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201010137451.1A 2010-03-31 2010-03-31 白血病相关的融合基因的联合检测方法及诊断试剂盒 Active CN101955991B (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201010137451.1A CN101955991B (zh) 2010-03-31 2010-03-31 白血病相关的融合基因的联合检测方法及诊断试剂盒
PCT/CN2011/072139 WO2011120398A1 (fr) 2010-03-31 2011-03-30 Procédé de détection conjointe de gènes de fusion de leucémie et trousses de diagnostic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201010137451.1A CN101955991B (zh) 2010-03-31 2010-03-31 白血病相关的融合基因的联合检测方法及诊断试剂盒

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CN101955991A CN101955991A (zh) 2011-01-26
CN101955991B true CN101955991B (zh) 2014-05-28

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CN (1) CN101955991B (fr)
WO (1) WO2011120398A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101955991B (zh) * 2010-03-31 2014-05-28 江苏迈迪基因生物科技有限公司 白血病相关的融合基因的联合检测方法及诊断试剂盒
CN103667453B (zh) * 2013-11-18 2015-06-17 福州艾迪康医学检验所有限公司 检测11q23/MLL融合基因相对表达量的方法、引物和探针
CN104278093B (zh) * 2014-09-28 2016-11-23 南京百捷生物科技有限公司 焦磷酸测序法检测sil-tal1融合基因的引物对及试剂盒
CN107151699A (zh) * 2017-06-01 2017-09-12 武汉艾迪康医学检验所有限公司 检测nup214‑abl1基因相对表达量的试剂盒和方法
CN114480456A (zh) * 2021-12-21 2022-05-13 安徽医科大学第二附属医院 用于检测多种融合基因的标准质粒及检测试剂盒

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009124901A1 (fr) * 2008-04-07 2009-10-15 Erasmus University Medical Center Rotterdam Procédés et kits de détection de protéines de fusion spécifiques des tumeurs
CN101624623A (zh) * 2008-07-11 2010-01-13 秦亚溱 一种定量检测ABL mRNA水平的试剂盒
GB2463401A (en) * 2008-11-12 2010-03-17 Caris Mpi Inc Diagnostic methods using exosomes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101955991B (zh) * 2010-03-31 2014-05-28 江苏迈迪基因生物科技有限公司 白血病相关的融合基因的联合检测方法及诊断试剂盒

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009124901A1 (fr) * 2008-04-07 2009-10-15 Erasmus University Medical Center Rotterdam Procédés et kits de détection de protéines de fusion spécifiques des tumeurs
CN101624623A (zh) * 2008-07-11 2010-01-13 秦亚溱 一种定量检测ABL mRNA水平的试剂盒
GB2463401A (en) * 2008-11-12 2010-03-17 Caris Mpi Inc Diagnostic methods using exosomes

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CN101955991A (zh) 2011-01-26

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