CN101932572A - 2-{4-[(3s)-哌啶-3-基]苯基}-2h-吲唑-7-羧酰胺的药学可接受的盐 - Google Patents

2-{4-[(3s)-哌啶-3-基]苯基}-2h-吲唑-7-羧酰胺的药学可接受的盐 Download PDF

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Publication number
CN101932572A
CN101932572A CN2009801018616A CN200980101861A CN101932572A CN 101932572 A CN101932572 A CN 101932572A CN 2009801018616 A CN2009801018616 A CN 2009801018616A CN 200980101861 A CN200980101861 A CN 200980101861A CN 101932572 A CN101932572 A CN 101932572A
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compound
inhibitors
compounds
cancer
phenyl
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Chinese (zh)
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J·R·富利
R·D·威尔逊
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Organon Pharma UK Ltd
Merck Sharp and Dohme LLC
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Merck Sharp and Dohme Ltd
Merck and Co Inc
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Application filed by Merck Sharp and Dohme Ltd, Merck and Co Inc filed Critical Merck Sharp and Dohme Ltd
Priority to CN201610345956.4A priority Critical patent/CN106008460B/zh
Publication of CN101932572A publication Critical patent/CN101932572A/zh
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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CN2009801018616A 2008-01-08 2009-01-08 2-{4-[(3s)-哌啶-3-基]苯基}-2h-吲唑-7-羧酰胺的药学可接受的盐 Pending CN101932572A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610345956.4A CN106008460B (zh) 2008-01-08 2009-01-08 2-{4-[(3s)-哌啶-3-基]苯基}-2h-吲唑-7-羧酰胺的药学可接受的盐

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1033308P 2008-01-08 2008-01-08
US61/010333 2008-01-08
PCT/GB2009/000041 WO2009087381A1 (en) 2008-01-08 2009-01-08 Pharmaceutically acceptable salts of 2-{4-[(3s)-piperidin-3- yl]phenyl} -2h-indazole-7-carboxamide

Related Child Applications (1)

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CN201610345956.4A Division CN106008460B (zh) 2008-01-08 2009-01-08 2-{4-[(3s)-哌啶-3-基]苯基}-2h-吲唑-7-羧酰胺的药学可接受的盐

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CN101932572A true CN101932572A (zh) 2010-12-29

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CN201610345956.4A Active CN106008460B (zh) 2008-01-08 2009-01-08 2-{4-[(3s)-哌啶-3-基]苯基}-2h-吲唑-7-羧酰胺的药学可接受的盐

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US (1) US8436185B2 (enExample)
EP (1) EP2240466B1 (enExample)
JP (1) JP5989965B2 (enExample)
KR (1) KR101653548B1 (enExample)
CN (2) CN101932572A (enExample)
AU (1) AU2009203598B2 (enExample)
BR (1) BRPI0906020A2 (enExample)
CA (1) CA2711491C (enExample)
ES (1) ES2548131T3 (enExample)
FR (1) FR18C1020I2 (enExample)
IL (1) IL206201A (enExample)
MX (1) MX337421B (enExample)
NL (1) NL300938I2 (enExample)
NZ (1) NZ586675A (enExample)
WO (1) WO2009087381A1 (enExample)
ZA (1) ZA201003902B (enExample)

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WO2018228474A1 (zh) * 2017-06-14 2018-12-20 上海时莱生物技术有限公司 聚(adp-核糖)聚合酶抑制剂、制备方法及用途
CN110300587A (zh) * 2017-04-04 2019-10-01 康姆芘法思催化剂股份有限公司 氘代(s)-2-(4-(哌啶-3-基)苯基)-2h-吲唑-7-甲酰胺
CN110709083A (zh) * 2017-03-27 2020-01-17 特沙诺有限公司 尼拉帕尼制剂
CN111065922A (zh) * 2017-09-13 2020-04-24 B.R.A.H.M.S有限公司 肾上腺髓质素原作为危重病患者的肾脏替代治疗的指标
CN111094986A (zh) * 2017-09-13 2020-05-01 B.R.A.H.M.S有限公司 基于肾上腺髓质素前体的指导流体治疗的方法
CN111094981A (zh) * 2017-09-13 2020-05-01 B.R.A.H.M.S有限公司 Pct和pro-adm作为监测抗生素治疗的标记物
CN111278433A (zh) * 2017-09-26 2020-06-12 特沙诺有限公司 尼拉帕尼制剂
US12297184B2 (en) 2018-10-03 2025-05-13 Tesaro, Inc. Niraparib salts

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CN108530425A (zh) * 2017-05-27 2018-09-14 广州科锐特生物科技有限公司 一种尼拉帕尼对甲苯磺酸盐水合物晶型及其制备方法
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IL206201A (en) 2014-07-31
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ES2548131T3 (es) 2015-10-14
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CN106008460A (zh) 2016-10-12
CA2711491C (en) 2016-03-08
AU2009203598A1 (en) 2009-07-16
MX337421B (es) 2016-03-04
FR18C1020I2 (fr) 2019-06-07
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US8436185B2 (en) 2013-05-07
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AU2009203598B2 (en) 2013-09-26
IL206201A0 (en) 2010-12-30
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