CN101910197B - 针对铜绿假单胞菌pcrv抗原的抗体 - Google Patents
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- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
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- C07K—PEPTIDES
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C—CHEMISTRY; METALLURGY
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K—PEPTIDES
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/567—Framework region [FR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
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- Life Sciences & Earth Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
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| PCT/US2008/085196 WO2009073631A2 (en) | 2007-11-30 | 2008-12-01 | Antibodies to the pcrv antigen of pseudomonas aeruginosa |
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| CN101910197A CN101910197A (zh) | 2010-12-08 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12492243B2 (en) | 2016-05-05 | 2025-12-09 | The Trustees Of The University Of Pennsylvania | DNA antibody constructs for use against Pseudomonas aeruginosa |
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| US9453251B2 (en) | 2002-10-08 | 2016-09-27 | Pfenex Inc. | Expression of mammalian proteins in Pseudomonas fluorescens |
| JP2008507294A (ja) | 2004-07-26 | 2008-03-13 | ダウ グローバル テクノロジーズ インコーポレイティド | 菌株遺伝子操作による改善されたタンパク質発現のための方法 |
| EP2615172A1 (en) * | 2007-04-27 | 2013-07-17 | Pfenex Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
| US9580719B2 (en) * | 2007-04-27 | 2017-02-28 | Pfenex, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
| KR101259239B1 (ko) | 2008-01-10 | 2013-04-29 | 시오노기세야쿠 가부시키가이샤 | ＰｃｒＶ에 대한 항체 |
| CA2751433A1 (en) * | 2009-02-04 | 2010-08-12 | Kalobios Pharmaceuticals, Inc. | Combination antibiotic and antibody therapy for the treatment of pseudomonas aeruginosa infection |
| PT2407537E (pt) * | 2009-03-11 | 2015-02-17 | Shionogi & Co | Anticorpo pcrv humanizado com atividade anti-pseudomonal |
| JP2013515079A (ja) * | 2009-12-22 | 2013-05-02 | カロバイオス ファーマシューティカルズ インコーポレイティッド | 低レベルの病原性シュードモナス・エルギノーサ（Ｐｓｅｕｄｏｍｏｎａｓａｅｒｕｇｉｎｏｓａ）感染症を有する患者のスタフィロコッカス（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ）感染症を治療する方法 |
| WO2012012571A1 (en) | 2010-07-21 | 2012-01-26 | Hans Zassenhaus | Biolayer interferometry measurement of biological targets |
| KR102111171B1 (ko) * | 2011-06-10 | 2020-05-14 | 메디뮨 엘엘씨 | 항슈도모나스 ｐｓｌ 결합 분자 및 그의 용도 |
| SMT202000542T1 (it) | 2011-11-07 | 2020-11-10 | Medimmune Ltd | Terapie di combinazione utilizzando molecole di legame anti-psl e pcrv di pseudomonas |
| JP6415987B2 (ja) | 2012-03-02 | 2018-10-31 | アブリンクス エン．ヴェー． | シュードモナス・エルギノーサのＰｃｒＶに結合する単一可変ドメイン抗体 |
| EP2917236A2 (en) * | 2012-11-06 | 2015-09-16 | MedImmune, LLC | Combination therapies using anti-pseudomonas psl and pcrv binding molecules |
| MX2017014002A (es) | 2015-05-01 | 2018-08-01 | Inhibrx Lp | Moléculas de direccionamiento del sistema de secreción tipo iii . |
| HUE051896T2 (hu) | 2015-07-16 | 2021-03-29 | Inhibrx Inc | Multivalens és multispecifikus DR5-kötõ fúziós fehérjék |
| CA3108071A1 (en) * | 2018-08-01 | 2020-02-06 | Cephalon, Inc. | Anti-cxcr2 antibodies and uses thereof |
| PH12021552903A1 (en) * | 2019-06-11 | 2022-04-04 | Regeneron Pharma | Anti-pcrv antibodies that bind pcrv, compositions comprising anti-pcrv antibodies, and methods of use thereof |
| CN114072145B (zh) * | 2020-06-01 | 2024-06-11 | 北京三诺佳邑生物技术有限责任公司 | 特异性识别假单胞菌pcrv的抗体及其用途 |
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| EP1049488A1 (en) * | 1998-11-25 | 2000-11-08 | MCW Research Foundation, Inc. | METHOD OF AND COMPOSITIONS FOR IMMUNIZATION WITH THE $i(PSEUDOMONAS) V ANTIGEN |
| WO2002064161A2 (en) * | 2001-01-26 | 2002-08-22 | Mcw Research Foundation, Inc. | Method and compositions for immunization with the pseudomonas v antigen |
| CN1788018A (zh) * | 2003-05-14 | 2006-06-14 | 伯纳生物技术有限公司 | 铜绿假单胞菌血清型iats o6的脂多糖(lps)特异性的人单克隆抗体 |
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| DE19918418C1 (de) * | 1999-04-23 | 2000-10-19 | Siegfried Mueller | Pflanzvorrichtung mit Halterung |
| AU2001238677A1 (en) | 2000-02-28 | 2001-09-12 | Idec Pharmaceuticals Corporation | Method for preparing anti-mif antibodies |
| CA2374027A1 (en) | 2001-03-13 | 2002-09-13 | The Minister Of National Defence | Cloning, expression, sequencing, and functional enhancement of monoclonal scfv antibody against venezuelan equine encephalitis virus(vee) |
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Cited By (1)
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| US12492243B2 (en) | 2016-05-05 | 2025-12-09 | The Trustees Of The University Of Pennsylvania | DNA antibody constructs for use against Pseudomonas aeruginosa |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20100097719A (ko) | 2010-09-03 |
| EP2220117A2 (en) | 2010-08-25 |
| JP2011505381A (ja) | 2011-02-24 |
| US8044181B2 (en) | 2011-10-25 |
| NZ586357A (en) | 2012-10-26 |
| CN101910197A (zh) | 2010-12-08 |
| IL206036A0 (en) | 2010-11-30 |
| AU2008333985B2 (en) | 2015-02-05 |
| US20120020986A1 (en) | 2012-01-26 |
| WO2009073631A3 (en) | 2009-09-24 |
| US8877191B2 (en) | 2014-11-04 |
| EA201000903A1 (ru) | 2011-02-28 |
| WO2009073631A2 (en) | 2009-06-11 |
| JP5781765B2 (ja) | 2015-09-24 |
| AU2008333985A1 (en) | 2009-06-11 |
| CA2706732A1 (en) | 2009-06-11 |
| SG186017A1 (en) | 2012-12-28 |
| MX2010005871A (es) | 2010-06-09 |
| US20090191186A1 (en) | 2009-07-30 |
| ZA201003852B (en) | 2014-11-26 |
| BRPI0819598A2 (pt) | 2017-05-09 |
| US20150030614A1 (en) | 2015-01-29 |
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