CN101904977B - Medicament for treating mastitis and preparation method thereof - Google Patents

Medicament for treating mastitis and preparation method thereof Download PDF

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Publication number
CN101904977B
CN101904977B CN2010102648557A CN201010264855A CN101904977B CN 101904977 B CN101904977 B CN 101904977B CN 2010102648557 A CN2010102648557 A CN 2010102648557A CN 201010264855 A CN201010264855 A CN 201010264855A CN 101904977 B CN101904977 B CN 101904977B
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medicine
radix
fructus
citrusaurantiuml
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CN101904977A (en
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葛德钜
周兵
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Abstract

The invention discloses a medicament for treating mastitis. The medicament is characterized by being mainly prepared from the following raw materials in part by weight: 1 to 20 parts of rose, 1 to 20 parts of seville orange flower, 1 to 20 parts of dandelion, 1 to 20 parts of trichosanthes, 1 to 20 parts of fructus forsythia, 1 to 20 parts of Chinese angelica, 1 to 20 parts of green tangerine peel, 1 to 20 parts of folium citri reticulatae, 1 to 20 parts of bulbus fritilariae, 1 to 20 parts of radix bupleuri, 1 to 20 parts of raw licorice root and 1 to 20 parts of over 95 percent edible alcohol. The medicament can be taken orally to be absorbed through spleen and stomach and applied externally to be absorbed through skin and can be compounded and absorbed through oral administration and external application. The medicament has the advantages of reasonable formula, compact compatibility, determined curative effect and capability of treating both principal and secondary aspect of disease. The invention also provides a method for preparing the medicament.

Description

A kind of medicine for the treatment of mastitis and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines, medicine of the treatment mastitis of particularly a kind of oral administration or external and preparation method thereof.
Background technology
Mastitis are meant acute and chronic mastitis, the mammary abscess that is caused by suppurative bacterium intrusion mammary gland, are one of reasons that causes puerperal fever, are most commonly in the nursing women, especially the primipara.Any time of age of sucking all can take place, and the beginning of suckling is the most common.Acute mastitis mainly is because latex dust is obstructed, make human milk silt, secondary bacterial infection, the treatment of acute mastitis inflammatory phase are the stages of comparison key, treat proper, inflammation can absorb and cure, otherwise will the form abscess, if primary disease is not thoroughly cured, can show effect repeatedly age of sucking, even form necrotic lesion in the breast duct later on, cause canceration.
Acute mastitis is many, and ailment said due to cold or exposure is attacked outward, or human milk silt because of cracked nipple, newborn network retardance, a kind of acute festering type disease that strongly fragrant heat-transformation of a specified duration forms.The traditional Chinese medical science usually is divided into it three types.1, stagnation of QI heat is stopped up symptom: the human milk silt caking, color of the leather is constant or little red, swelling pain.With fever with aversion to cold, headache, aching of the whole body, thirsty, constipation.Yellow fur, rapid pulse.2, excessive noxious heat, symptom: high fever, breast swell and pain, skin-red scorching hot, the lump deliquescing has to refer to sense.Or inadequate drainage after the incision evacuation of pus, red and swollen heat pain does not disappear, and " biography capsule " phenomenon is arranged.Red tongue, yellow and greasy fur, full and rapid pulse.3, weakened body resistance poison is loved symptom: though the pus rear udder attachment of bursting swells and ache gently, open sore part pus is continuous, and pus is rare clearly, indolence or formation mammary fistula.Malaise, lustreless complexion, or low grade fever does not move back the diet minimizing.Light red tongue, thin fur, weak pulse are unable.
Chinese patent CN200710146017.8 discloses a kind of Chinese medicine composition for the treatment of mastitis, mainly being made up of 14 kinds of Chinese herbal medicine such as stir-baked SQUAMA MANITIS, Flos Carthami, Sanguis Draxonis, Olibanum, Hedyotidis Diffusae, Spina Gleditsiae, Semen Vaccariae, Herba Taraxaci, Herba Violae, Flos Loniceraes, is that fine powder is made electuary with raw material pulverizing.Chinese patent CN01118081.1 discloses a kind of Chinese medicine composition for the treatment of acute mastitis, cyclomastopathy and hysteromyoma, be by Zaocys 10-20g, Scolopendra 1-4 bar, Mylabris 5-10, Semen Ricini 2-4g, Squama Manis 8-20g, Uroctea compatilis Koch. 5-10, Flos Chrysanthemi 10-15g, Huechys sanguinea De Geer. 5-10, Bombyx bombycis 5-13, Cera Flava 20-50g, Oleum sesami 200ml, go into the raw material except that Cera Flava in the Oleum sesami in proportion, fried to little Huang, be ground into powder after pulling out, with the Cera Flava heat fused, add the medicated powder mixing, make pill.
The Chinese medicine product of above-mentioned treatment mastitis is paid attention to regulating too much, and used taste of Chinese medicine number is too much, has reduced the medicine proportion of a therapeutical effect relatively, has influenced the pharmic function performance, so effect is slow, the course of treatment is long, and effect is undesirable.And existing Chinese medicine oral administration but can not external, but can not the taking orally again of external, route of administration is single, makes the patient slow to the absorption of medicine.Chinese medicine for oral administration not only absorbs slowly, and causes spleen injury easily, even increase the weight of the state of an illness for the patient of weakness of the spleen and stomach.
Chinese medicine is taken difficulty owing to mostly be decoction or the pill that boils than Western medicine, has also influenced the popularization of Chinese medicine widely.
Summary of the invention
The objective of the invention is to overcome the defective that prior art exists, a kind of reasonable recipe is provided, compatibility is simplified, the medicine of the treatment mastitis of determined curative effect, treating both the principal and secondary aspects of a disease, to control, control foster combination, and this medicine can take orally by taste absorb again can external by skin absorbs, can also oral administration and externally used dual mode composite absorption.This compound administering mode helps the efficient absorption of human body to medicine, and for the crowd of weakness of the spleen and stomach, the medicine that is busy with one's work, spares oneself provides multiple choices, especially the patient by the modern job crowd is accepted.
Technical scheme of the present invention is as follows:
A kind of medicine for the treatment of mastitis is characterized in that it mainly is to be made by the raw material of following weight portion: 1 ~ 20 part of Flos Rosae Rugosae, 1 ~ 20 part of CitrusaurantiumL.Var.amara Engl., 1 ~ 20 part of Herba Taraxaci, 1 ~ 20 part of Fructus Trichosanthis, 1 ~ 20 part of Fructus Forsythiae, 1 ~ 20 part of Radix Angelicae Sinensis, 1 ~ 20 part on Pericarpium Citri Reticulatae Viride, 1 ~ 20 part of Folium Citri tangerinae, 1 ~ 20 part of Bulbus Fritillariae Cirrhosae, 1 ~ 20 part of Radix Bupleuri, 1 ~ 20 part of 1 ~ 20 part of Radix Glycyrrhizae, the content edible ethanol more than 95%.
Further, the consumption of each component of medicine of the present invention is: 15 ~ 20 parts of Flos Rosae Rugosaes, 15 ~ 20 parts of CitrusaurantiumL.Var.amara Engl.s, 15 ~ 20 parts of Herba Taraxacis, 15 ~ 20 parts of Fructus Trichosanthis, 15 ~ 20 parts of Fructus Forsythiaes, 15 ~ 20 parts of Radix Angelicae Sinensis, 15 ~ 20 parts on Pericarpium Citri Reticulatae Viride, 15 ~ 20 parts of Folium Citri tangerinae, 15 ~ 20 parts of Bulbus Fritillariae Cirrhosae, 15 ~ 20 parts of Radix Bupleuri, 15 ~ 20 parts of 15 ~ 20 parts of Radix Glycyrrhizae, the content edible ethanols more than 95%.
The middle survival dose of above compatibility is the crude drug amount.
In order to strengthen the transdermal effect of medicine, can also mix transdermal agent in the medicine of the present invention, preferably weight portion is 1 ~ 5 part a azone.
Another object of the present invention provides manufacturing method for above mentioned medicine, it is characterized in that comprising the following steps:
A) take by weighing Flos Rosae Rugosae, CitrusaurantiumL.Var.amara Engl., Herba Taraxaci, Fructus Trichosanthis, Fructus Forsythiae, Radix Angelicae Sinensis, Pericarpium Citri Reticulatae Viride, Folium Citri tangerinae, Bulbus Fritillariae Cirrhosae, Radix Bupleuri and the Radix Glycyrrhizae of described weight proportion, according to the conventional extracting method of Chinese medicine, the extract of the former medicine that obtains respectively respectively to distinguish the flavor of;
B) under the room temperature, get the deionized water of 5 ~ 6 times of amounts, add the edible ethanol of content more than 95% of described weight proportion, be mixed with aqueous solution of alcohol;
C) with in the above-mentioned aqueous solution of alcohol of the extract obtained adding of step a, stirred 120 minutes, precipitate 2 ~ 4 hours, filter, gained filtrate sterilization, fill according to quantity must be treated the medicine of mastitis.
Further, among the step c, can add in the aqueous solution of alcohol together by azone step a is extract obtained and 1 ~ 5 weight portion.
The conventional extracting method of described Chinese crude drug can adopt decocting method, circumfluence method, infusion process, percolation, semi-bionic extraction, supercritical fluid extraction, microwave extraction method etc. according to the kind of medical material.
The present invention is directed to the characteristics of mastitis, select Flos Rosae Rugosae, CitrusaurantiumL.Var.amara Engl., Herba Taraxaci, Fructus Trichosanthis, Fructus Forsythiae, Radix Angelicae Sinensis, Pericarpium Citri Reticulatae Viride, Folium Citri tangerinae, Bulbus Fritillariae Cirrhosae, Radix Bupleuri, Radix Glycyrrhizae for use, with being that edible ethanol more than 95% mixes with content after each flavor Chinese medicine extraction, make to contain pure Chinese medicine extraction liquid.Employing to be to control, and control and support bonded method, but not only also external of oral administration of the medicine of making is a kind of reasonable recipe, and compatibility is simplified, the medicine of the treatment mastitis of determined curative effect, treating both the principal and secondary aspects of a disease.
Herba Taraxaci nature and flavor hardship, sweet, cold.Return liver, stomach warp, heat-clearing and toxic substances removing, the diuresis eliminating stagnation is controlled acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis etc.Sweet, the little hardship of Fructus Trichosanthis nature and flavor, cold; Return lung, stomach, large intestine channel, clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens is moisturized laxation.Fructus Forsythiae nature and flavor hardship is slightly cold, and returns lung, the heart, gallbladder meridian; Heat-clearing and toxic substances removing, the eliminating carbuncle eliminating stagnation.The sweet suffering of Radix Angelicae Sinensis, temperature is gone into the heart, liver, spleen channel; Benefiting blood and regulating blood circulation; Menstruction regulating and pain relieving is moisturized laxation.Pericarpium Citri Reticulatae Viride nature and flavor hardship, suffering, temperature.Go into liver, gallbladder meridian; Soothing the liver dispelling the stagnated QI, the eliminating stagnation expectorant.Folium Citri tangerinae nature and flavor toil, flat, soothing the liver, circulation of qi promoting is reduced phlegm, and the detumescence poison is controlled hypochondriac pain, acute mastitis, lung abscess, cough, chest and diaphragm feeling of fullness, hernia.The Bulbus Fritillariae Cirrhosae bitter but sweet flavor, lung meridian is gone in cold; The lung moistening eliminating stagnation, antitussive reduces phlegm.The Radix Bupleuri hardship, liver, gallbladder meridian are gone in cold; Reconciling superficies and interior, soothing the liver, yang invigorating.The Radix Glycyrrhizae nature and flavor are sweet, and are flat, go into spleen, stomach, lung meridian; With middle emergency, lung moistening, detoxifcation, coordinating the actions of various ingredients in a prescription.
The present invention is with Herba Taraxaci, Fructus Forsythiae heat-clearing and toxic substances removing; Fructus Trichosanthis, the Bulbus Fritillariae Cirrhosae dissipating phlegm and resolving masses; The Radix Angelicae Sinensis eliminating carbuncle of invigorating blood circulation; Pericarpium Citri Reticulatae Viride, Folium Citri tangerinae, Radix Bupleuri depressed liver-energy dispersing and QI regulating; Radix Glycyrrhizae detoxifcation and in.We's prescription is rigorous, compatibility is intricately woven together.
Flos Rosae Rugosae regulate the flow of vital energy resolving depression and blood dissipating blood stasis; The CitrusaurantiumL.Var.amara Engl. the chest stuffiness relieving of regulating the flow of vital energy, dispersing the stagnated liver-QI for regulating the stomach, appetizing preventing or arresting vomiting.Two medicines, 5 usefulness, a gas one blood, QI and blood is two transfers, eliminating turbid pathogen with aromatics, the appetizing of being amusing, the strength enhancing that absorbs the drug when oral.The edible ethanol blood circulation promoting and blood stasis dispelling of content more than 95% promotes that drug osmotic to cell absorbs, and auxiliary taste absorb to improve curative effect when oral; Outer time spent skin expansion pore is to strengthen the drug transdermal trap.
Medicine of the present invention can also be smeared the affected part with medicine of the present invention except for oral administration, and the efficacy of a drug sick institute that goes directly so can remove the patient suffering, obtains and imitates in no time.This medicine is applicable to that also whole body smears.Adopt oral administration and externally usedly, drug effect is more remarkable.
It is obvious that the present invention treats the mastitis curative effect, can soothing the liver clearing stomach, and the stimulating milk secretion eliminating carbuncle.Clinical usefulness repeatly, effect are very prompt.Medicine of the present invention is through clinical 75 routine patients' clinical verification, and curing number is 60 examples, and significant figure is 11 examples, and invalid number is 4 examples, and total effective rate reaches 95%.Control and do not see toxic side effect in the therapeutic process, the patient has better curative effect to obstinate.
For further specifying therapeutic effect, it is as follows now to enumerate model case:
Case 1: certain woman 25 years old, the primipara suffers from mastitis, mammary swelling, pain, heating.Oral medicine of the present invention, each 10 milliliters, every day 3 times, above symptom was alleviated in 3 days, eliminated in 30 days.Paying a return visit after 12 months does not have recurrence.
Case 2: certain woman 28 years old, be in age of sucking, suffer from mastitis, breast portion caking, pain.This medicine of external is smeared whole body and chest, every day 2 times, each 10 milliliters.Above symptom was alleviated in 2 days, eliminated in 26 days.Paying a return visit after 9 months does not have recurrence.
Case 3: certain woman 30 years old, suffer from mastitis, mammary swelling, aversion to cold, heating.Once took the Chinese medicine of multiple treatment mastitis, but effect is all not good.Oral medicine of the present invention, each 10 milliliters, every day 3 times; This medicine of external is smeared whole body and chest, every day 2 times, each 10 milliliters.Above symptom is oral to be alleviated with external in 1 day, eliminated in 20 days.Paying a return visit after 8 months does not have recurrence.
The specific embodiment
Embodiment 1
Take by weighing 15 parts of Flos Rosae Rugosaes, 18 parts of CitrusaurantiumL.Var.amara Engl.s, 15 parts of Herba Taraxacis, 18 parts of Fructus Trichosanthis, 17 parts of Fructus Forsythiaes, 16 parts of Radix Angelicae Sinensis, 20 parts on Pericarpium Citri Reticulatae Viride, 19 parts of Folium Citri tangerinae, 19 parts of Bulbus Fritillariae Cirrhosae, 18 parts of Radix Bupleuri, 18 parts of Radix Glycyrrhizae adopt the method that decocts the back concentrating under reduced pressure to make Chinese medicine extract respectively, and are standby.
Under the room temperature, get the deionized water of 5 ~ 6 times of amounts, add content and be 18 parts of 96% edible ethanols, be mixed with aqueous solution of alcohol, standby.
Above-mentioned various Chinese medicine extract are added in the aqueous solution of alcohol, fully stirred 120 minutes, precipitate 2 ~ 4 hours, supernatant 200 orders filter, and gained filtrate is the medicine of the treatment mastitis of oral administration or external, carries out fill under aseptic condition.Gained precipitate and filtering residue focus on.
Embodiment 2
The drug component proportioning is: 18 parts of Flos Rosae Rugosaes, and 19 parts of CitrusaurantiumL.Var.amara Engl.s, 18 parts of Herba Taraxacis, 18 parts of Fructus Trichosanthis, 19 parts of Fructus Forsythiaes, 19 parts of Radix Angelicae Sinensis, 18 parts on Pericarpium Citri Reticulatae Viride, 20 parts of Folium Citri tangerinae, 20 parts of Bulbus Fritillariae Cirrhosae, 18 parts of Radix Bupleuri, 19 parts of Radix Glycyrrhizae, content are 18 parts of 97% edible ethanols.Other is identical with embodiment 1.
Embodiment 3
The drug component proportioning is: 19 parts of Flos Rosae Rugosaes, and 20 parts of CitrusaurantiumL.Var.amara Engl.s, 20 parts of Herba Taraxacis, 19 parts of Fructus Trichosanthis, 19 parts of Fructus Forsythiaes, 19 parts of Radix Angelicae Sinensis, 19 parts on Pericarpium Citri Reticulatae Viride, 20 parts of Folium Citri tangerinae, 19 parts of Bulbus Fritillariae Cirrhosae, 20 parts of Radix Bupleuri, 20 parts of Radix Glycyrrhizae, content are 18 parts of 98% edible ethanols.Other is identical with embodiment 1.
Embodiment 4
The drug component proportioning is: 16 parts of Flos Rosae Rugosaes, and 17 parts of CitrusaurantiumL.Var.amara Engl.s, 17 parts of Herba Taraxacis, 16 parts of Fructus Trichosanthis, 15 parts of Fructus Forsythiaes, 16 parts of Radix Angelicae Sinensis, 17 parts on Pericarpium Citri Reticulatae Viride, 16 parts of Folium Citri tangerinae, 16 parts of Bulbus Fritillariae Cirrhosae, 17 parts of Radix Bupleuri, 18 parts of Radix Glycyrrhizae, content are 16 parts of 99% edible ethanols.Other is identical with embodiment 1.
Embodiment 5
The drug component proportioning is: 15 parts of Flos Rosae Rugosaes, and 18 parts of CitrusaurantiumL.Var.amara Engl.s, 15 parts of Herba Taraxacis, 16 parts of Fructus Trichosanthis, 18 parts of Fructus Forsythiaes, 18 parts of Radix Angelicae Sinensis, 20 parts on Pericarpium Citri Reticulatae Viride, 18 parts of Folium Citri tangerinae, 19 parts of Bulbus Fritillariae Cirrhosae, 19 parts of Radix Bupleuri, 19 parts of Radix Glycyrrhizae, content are 19 parts of 100% edible ethanols.Other is identical with embodiment 1.
Embodiment 6
The drug component proportioning is: 18 parts of Flos Rosae Rugosaes, and 20 parts of CitrusaurantiumL.Var.amara Engl.s, 18 parts of Herba Taraxacis, 18 parts of Fructus Trichosanthis, 20 parts of Fructus Forsythiaes, 17 parts of Radix Angelicae Sinensis, 16 parts on Pericarpium Citri Reticulatae Viride, 18 parts of Folium Citri tangerinae, 19 parts of Bulbus Fritillariae Cirrhosae, 18 parts of Radix Bupleuri, 19 parts of Radix Glycyrrhizae, content are 20 parts of 97% edible ethanols.Other is identical with embodiment 1.

Claims (6)

1. a medicine for the treatment of mastitis is characterized in that it is to be made by the raw material of following weight portion: 1 ~ 20 part of Flos Rosae Rugosae, 1 ~ 20 part of CitrusaurantiumL.Var.amara Engl., 1 ~ 20 part of Herba Taraxaci, 1 ~ 20 part of Fructus Trichosanthis, 1 ~ 20 part of Fructus Forsythiae, 1 ~ 20 part of Radix Angelicae Sinensis, 1 ~ 20 part on Pericarpium Citri Reticulatae Viride, 1 ~ 20 part of Folium Citri tangerinae, 1 ~ 20 part of Bulbus Fritillariae Cirrhosae, 1 ~ 20 part of Radix Bupleuri, 1 ~ 20 part of 1 ~ 20 part of Radix Glycyrrhizae, the content edible ethanol more than 95%.
2. medicine as claimed in claim 1 is characterized in that it is to be made by the raw material of following weight portion: 15 ~ 20 parts of Flos Rosae Rugosaes, 15 ~ 20 parts of CitrusaurantiumL.Var.amara Engl.s, 15 ~ 20 parts of Herba Taraxacis, 15 ~ 20 parts of Fructus Trichosanthis, 15 ~ 20 parts of Fructus Forsythiaes, 15 ~ 20 parts of Radix Angelicae Sinensis, 15 ~ 20 parts on Pericarpium Citri Reticulatae Viride, 15 ~ 20 parts of Folium Citri tangerinae, 15 ~ 20 parts of Bulbus Fritillariae Cirrhosae, 15 ~ 20 parts of Radix Bupleuri, 15 ~ 20 parts of 15 ~ 20 parts of Radix Glycyrrhizae, the content edible ethanols more than 95%.
3. a medicine for the treatment of mastitis is characterized in that, it is to be made by the raw material of following weight portion: 1 ~ 20 part of Flos Rosae Rugosae, 1 ~ 20 part of CitrusaurantiumL.Var.amara Engl., 1 ~ 20 part of Herba Taraxaci, 1 ~ 20 part of Fructus Trichosanthis, 1 ~ 20 part of Fructus Forsythiae, 1 ~ 20 part of Radix Angelicae Sinensis, 1 ~ 20 part on Pericarpium Citri Reticulatae Viride, 1 ~ 20 part of Folium Citri tangerinae, 1 ~ 20 part of Bulbus Fritillariae Cirrhosae, 1 ~ 20 part of Radix Bupleuri, 1 ~ 20 part of Radix Glycyrrhizae, 1 ~ 20 part of the edible ethanol of content more than 95%, 1 ~ 5 part of azone.
4. medicine as claimed in claim 3 is characterized in that it is to be made by the raw material of following weight portion: 15 ~ 20 parts of Flos Rosae Rugosaes, 15 ~ 20 parts of CitrusaurantiumL.Var.amara Engl.s, 15 ~ 20 parts of Herba Taraxacis, 15 ~ 20 parts of Fructus Trichosanthis, 15 ~ 20 parts of Fructus Forsythiaes, 15 ~ 20 parts of Radix Angelicae Sinensis, 15 ~ 20 parts on Pericarpium Citri Reticulatae Viride, 15 ~ 20 parts of Folium Citri tangerinae, 15 ~ 20 parts of Bulbus Fritillariae Cirrhosae, 15 ~ 20 parts of Radix Bupleuri, 15 ~ 20 parts of 15 ~ 20 parts of Radix Glycyrrhizae, the content edible ethanols more than 95%, 1 ~ 5 part of azone.
5. the preparation method of claim 1 or 2 described medicines is characterized in that comprising the following steps:
A) take by weighing Flos Rosae Rugosae, CitrusaurantiumL.Var.amara Engl., Herba Taraxaci, Fructus Trichosanthis, Fructus Forsythiae, Radix Angelicae Sinensis, Pericarpium Citri Reticulatae Viride, Folium Citri tangerinae, Bulbus Fritillariae Cirrhosae, Radix Bupleuri and the Radix Glycyrrhizae of described weight proportion, according to the conventional extracting method of Chinese medicine, the extract of the raw material that obtains respectively respectively to distinguish the flavor of;
B) under the room temperature, get the deionized water of 5 ~ 6 times of amounts, add the edible ethanol of content more than 95% of described weight proportion, be mixed with aqueous solution of alcohol;
C) with in the above-mentioned aqueous solution of alcohol of the extract obtained adding of step a, stirred 120 minutes, precipitate 2 ~ 4 hours, filter, gained filtrate sterilization, fill according to quantity must be treated the medicine of mastitis.
6. the preparation method of claim 3 or 4 described medicines is characterized in that comprising the following steps:
A) take by weighing Flos Rosae Rugosae, CitrusaurantiumL.Var.amara Engl., Herba Taraxaci, Fructus Trichosanthis, Fructus Forsythiae, Radix Angelicae Sinensis, Pericarpium Citri Reticulatae Viride, Folium Citri tangerinae, Bulbus Fritillariae Cirrhosae, Radix Bupleuri and the Radix Glycyrrhizae of described weight proportion, according to the conventional extracting method of Chinese medicine, the extract of the raw material that obtains respectively respectively to distinguish the flavor of;
B) under the room temperature, get the deionized water of 5 ~ 6 times of amounts, add the edible ethanol of content more than 95% of described weight proportion, be mixed with aqueous solution of alcohol;
C) azone step a is extract obtained and described weight proportion adds in the aqueous solution of alcohol together, stirs 120 minutes, precipitates 2 ~ 4 hours, filter, and gained filtrate sterilization, fill according to quantity must be treated the medicine of mastitis.
CN2010102648557A 2010-08-27 2010-08-27 Medicament for treating mastitis and preparation method thereof Expired - Fee Related CN101904977B (en)

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CN102670878B (en) * 2012-05-04 2013-08-14 刘超 Traditional Chinese medicine decoction for treating acute mastitis
CN103989977A (en) * 2014-04-21 2014-08-20 史家举 Traditional Chinese medicinal composition for treating acute mastitis
CN104605067A (en) * 2014-12-31 2015-05-13 广州至信中药饮片有限公司 Breast beautifying tea and preparation method of tea
CN105795046A (en) * 2016-03-15 2016-07-27 湖北明钼健康科技有限公司 Nipple health caring instant brewing tea
CN112138070A (en) * 2020-10-16 2020-12-29 刘怡彤 Preparation method of traditional Chinese medicine for treating acute mastitis
CN113813359A (en) * 2021-08-22 2021-12-21 天津市天大天福生物技术有限公司 Technology and product preparation for treating migraine, arthralgia, stagnation and inflammation by using antibacterial peptide for dredging channels and collaterals and carrying out transdermal administration on lymph
CN115364167A (en) * 2022-09-29 2022-11-22 北京赛孚生物制药股份有限公司 Traditional Chinese medicine oral liquid for treating cow mastitis and preparation method thereof

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CN1739736A (en) * 2005-09-13 2006-03-01 师宇 Medicine prepn for treating nodules of breast
CN101129993A (en) * 2007-09-24 2008-02-27 北京艺信堂医药研究所 Traditional Chinese medicine composition for treating gland hyperplasia

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