CN101987159B - Medicine for treating erysipelas and preparation method thereof - Google Patents
Medicine for treating erysipelas and preparation method thereof Download PDFInfo
- Publication number
- CN101987159B CN101987159B CN2010102649282A CN201010264928A CN101987159B CN 101987159 B CN101987159 B CN 101987159B CN 2010102649282 A CN2010102649282 A CN 2010102649282A CN 201010264928 A CN201010264928 A CN 201010264928A CN 101987159 B CN101987159 B CN 101987159B
- Authority
- CN
- China
- Prior art keywords
- parts
- medicine
- erysipelas
- chinese medicine
- herba
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a medicine for treating erysipelas, which is characterized by mainly comprising the following raw materials in parts by weight: 1-20 parts of rose, 1-20 parts of seville orange flower, 1-20 parts of dandelion, 1-20 parts of mother chrysanthemum, 1-20 parts of folium isatidis, 1-20 parts of Chinese violet, 1-20 parts of manyleaf paris rhizome, 1-20 parts of radices trichosanthis, 1-20 parts of root of common peony and 1-20 parts of edible alcohol the content of which is at least 95 percent. The medicine not only can be taken orally to be absorbed by the spleen and the stomach, but also can be externally used to be absorbed by skins and can also be taken orally and externally used to be compositely absorbed. The medicine has reasonable formula, simple compatibility and exact curative effect and treats both principal and secondary aspects of diseases. The invention also provides a preparation method for the medicine.
Description
Technical field
The invention belongs to the field of Chinese medicines, medicine of the treatment erysipelas of particularly a kind of oral administration or external and preparation method thereof.
Background technology
Erysipelas is the skin that caused by hemolytic streptococcal infection or the acute inflammation of mucosa, subcutaneous tissue endolymphatic duct and surrounding tissue thereof, is commonly called as " erysipelas ".Skin or the fine breakage of mucosa are often arranged before the onset.Erysipelas is sent out in lower limb and face well.Its clinical manifestation is that onset is anxious, and the lamellar erythema of boundary clear appears in the part, and color is scarlet, and swells slightly, and that presses fades.The skin surface anxiety is red-hot, rapidly to around spread, burn appearance pain.Companion's hyperpyrexia fear of cold and headache etc.Though erysipelas is not that viral infection causes with " poison " name, but the acute festering type corium inflammation that causes by bacterial infection.Its pathogen is an A family beta hemolytic streptococcus, how hinders and invades by skin or mucosa are broken, but also can be by hematogenous infection.
Chinese medicine thinks that the cause of disease of erysipelas is main with fire-toxin, can be caused by all evil fire-transformation of rheumatic fever.
One Chinese patent application CN200810133149.1 discloses a kind of Chinese medicine composition of treating erysipelas, is made up of following medicine by mass percentage; Folium Isatidis 57%, Radix Sophorae Flavescentis 22%, the content summation of Cortex Dictamni 21%, three herbal medicine is 10 0%.With above-mentioned three herbal medicines with being decocted in water for oral dose.One Chinese patent application CN200710122276.7 discloses a kind of Chinese medicine decoction of treating erysipelas of breast, and it is to be raw material with 10 Chinese medicine medicines such as Gypsum Fibrosum, the Rhizoma Anemarrhenae, Cornu Bubali and Cortex Moutans.
The Chinese medicine product of above-mentioned treatment erysipelas is too much paid attention to regulating, and used taste of Chinese medicine number is too much, has reduced the medicine proportion of a therapeutical effect relatively, has influenced the pharmic function performance, so effect is slow, the course of treatment is long, and effect is undesirable.And existing Chinese medicine oral administration but can not external, but can not the taking orally again of external, route of administration is single, makes the patient slow to the absorption of medicine.Chinese medicine for oral administration not only absorbs slowly, and causes spleen injury easily, even increase the weight of the state of an illness for the patient of weakness of the spleen and stomach.
Chinese medicine is taken difficulty owing to the decoction or the pill that are mostly to boil than Western medicine, has also influenced the popularization of Chinese medicine widely.
Summary of the invention
The objective of the invention is to overcome the defective that prior art exists; A kind of reasonable recipe is provided; Compatibility is simplified, the medicine of the treatment erysipelas of determined curative effect, treating both the principal and secondary aspects of a disease, is main to control, and controls to support to combine; And this medicine can take orally through taste absorb again can external through skin absorbs, can also oral administration and externally used dual mode composite absorbent.This compound administering mode helps the efficient absorption of human body to medicine, and for the crowd of weakness of the spleen and stomach, the medicine that is busy with one's work, spares oneself provides multiple choices, especially the patient by the modern job crowd is accepted.
Technical scheme of the present invention is following:
A kind of medicine of treating erysipelas is characterized in that it mainly is to be processed by the raw material of following weight portion: 1 ~ 20 part of Flos Rosae Rugosae, 1 ~ 20 part of CitrusaurantiumL.Var.amara Engl.; 1 ~ 20 part of Herba Taraxaci, 1 ~ 20 part of Flos Chrysanthemi Indici, 1 ~ 20 part of Folium Isatidis; 1 ~ 20 part of Herba Violae, 1 ~ 20 part of Rhizoma Paridis, 1 ~ 20 part of Radix Trichosanthis; 1 ~ 20 part of 1 ~ 20 part of Radix Paeoniae Rubra, the content edible ethanol more than 95%.
Further, the consumption of each component of medicine of the present invention is: 15 ~ 20 parts of Flos Rosae Rugosaes, 15 ~ 20 parts of CitrusaurantiumL.Var.amara Engl.s; 15 ~ 20 parts of Herba Taraxacis, 15 ~ 20 parts of Flos Chrysanthemi Indicis, 15 ~ 20 parts of Folium Isatidiss; 15 ~ 20 parts of Herba Violaes, 15 ~ 20 parts of Rhizoma Paridis, 15 ~ 20 parts of Radix Trichosanthis; 15 ~ 20 parts of 15 ~ 20 parts of Radix Paeoniae Rubra, the content edible ethanols more than 95%.
The middle survival dose of above compatibility is the crude drug amount.
In order to strengthen the transdermal effect of medicine, can also mix transdermal agent in the medicine of the present invention, preferably weight portion is 1 ~ 5 part a azone.
Another object of the present invention provides manufacturing method for above mentioned medicine, it is characterized in that comprising the following steps:
A) take by weighing Flos Rosae Rugosae, CitrusaurantiumL.Var.amara Engl., Herba Taraxaci, Flos Chrysanthemi Indici, Folium Isatidis, Herba Violae, Rhizoma Paridis, Radix Trichosanthis and the Radix Paeoniae Rubra of said weight proportion, according to the conventional method for distilling of Chinese medicine, the extract of the former medicine that obtains respectively respectively to distinguish the flavor of;
B) under the room temperature, get the deionized water of 5 ~ 6 times of amounts, add the edible ethanol of content more than 95% of said weight proportion, be mixed with aqueous solution of alcohol;
C) with in the above-mentioned aqueous solution of alcohol of the extract obtained adding of step a, stirred 120 minutes, precipitate 2 ~ 4 hours, filter, gained filtrating sterilization, fill according to quantity must be treated the medicine of erysipelas.
Further, among the step c, can add in the aqueous solution of alcohol together by azone step a is extract obtained and 1 ~ 5 weight portion.
The conventional method for distilling of said Chinese crude drug can adopt decocting method, circumfluence method, infusion process, percolation, semi-bionic extraction, supercritical fluid extraction, microwave extraction method etc. according to the kind of medical material.
The present invention is directed to the characteristics of erysipelas; Select Flos Rosae Rugosae, CitrusaurantiumL.Var.amara Engl., Herba Taraxaci, Flos Chrysanthemi Indici, Folium Isatidis, Herba Violae, Rhizoma Paridis, Radix Trichosanthis, Radix Paeoniae Rubra for use; With being that edible ethanol more than 95% mixes with content after each flavor Chinese medicine extraction, process to contain pure Chinese medicine extraction liquid.Employing is main to control, and control the bonded method of supporting, but not only also external of oral administration of the medicine of processing is a kind of reasonable recipe, and compatibility is simplified, the medicine of the treatment erysipelas of determined curative effect, treating both the principal and secondary aspects of a disease.
Herba Taraxaci property bitter but sweet flavor, cold, go into liver, stomach warp, heat-clearing and toxic substances removing, diuresis eliminating stagnation.Flos Chrysanthemi Indici nature and flavor toil, lung, liver are gone in cold; Wind and heat dispersing, subduing swelling and detoxicating.The Folium Isatidis nature and flavor are bitter, and are cold, go into liver, the heart, stomach warp; Heat clearing away, detoxifcation, removing heat from blood, hemostasis.The Herba Violae nature and flavor are bitter, hot, and are cold, GUIXIN, Liver Channel; Heat-clearing and toxic substances removing, the removing heat from blood detumescence is used for furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom.Rhizoma Paridis nature and flavor toil, cold, poisonous, go into the heart, Liver Channel, heat-clearing and toxic substances removing, antiasthmatic-antitussive, arresting convulsion relieves dizziness, high fever, infantile convulsions, epilepsy, etc.The acid of Radix Trichosanthis nature and flavor sweetness and bitterness, lung, stomach warp are gone in cold; Promote the production of body fluid, quench the thirst, pathogenic fire reducing is moisturized, evacuation of pus, detumescence.The Radix Paeoniae Rubra nature and flavor are bitter, are slightly cold, and return Liver Channel; Clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, pain relieving.
Eliminating carbuncle is longer than in the Herba Taraxaci detoxifcation in the medicine of the present invention; The treatment poison is longer than in the Herba Violae detoxifcation; Folium Isatidis detoxifcation clearing away heat and cooling blood is usually used in treating diseases such as pestilence macule, erysipelas; Rhizoma Paridis can separate liver and gall hot and suffocating, put out the fire-toxin of disturbing, the kind part of the body cavity above the diaphragm housing the heart and lungs carbuncle sore tumefacting virus of controlling; Assistant is with Radix Paeoniae Rubra removing heat from blood and promoting blood circulation dissipating blood stasis; The pollen clearing away heat and promoting production of body fluid protects the moon.Medicine is special less, and Each answers the purpose intended.Can work in coordination with the detoxifcation heat clearing away, and speciality is respectively arranged, so be applicable to the initial stage that all body surfaces such as treatment, furuncle, carbuncle, acute erysipelas infect.We are the heat clearing away of specially detoxifying of the first-selected good recipe of heat-clearing and toxic substances removing, power.
Flos Rosae Rugosae regulate the flow of vital energy resolving depression and blood dissipating blood stasis; The CitrusaurantiumL.Var.amara Engl. the chest stuffiness relieving of regulating the flow of vital energy, dispersing the stagnated liver-QI for regulating the stomach, appetizing preventing or arresting vomiting.Two medicines, 5 usefulness, a gas one blood, QI and blood is two to be transferred, eliminating turbid pathogen with aromatics, the appetizing of being amusing, the strength enhancing that absorbs the drug when oral.The edible ethanol blood circulation promoting and blood stasis dispelling of content more than 95% promotes that drug osmotic to cell absorbs, and auxiliary taste absorb to improve curative effect when oral; Outer time spent skin expansion pore is to strengthen the drug transdermal trap.
Medicine of the present invention can also be smeared the affected part with medicine of the present invention except for oral administration, and the efficacy of a drug sick institute that goes directly so can remove the hardship of patient's headache, obtains and imitates in no time.This medicine is applicable to that also whole body smears.Adopt oral administration and externally usedly, drug effect is more remarkable.
It is obvious that the present invention treats the erysipelas curative effect, and clinical usefulness repeatly, effect are very prompt.Medicine of the present invention is through clinical 90 routine patients' clinical verification, and curing number is 72 examples, and significant figure is 15 examples, and invalid number is 3 examples, and total effective rate reaches 96.6%.Do not see toxic side effect in the therapeutic process, the patient has better curative effect to obstinate.
For further specifying therapeutic effect, to enumerate model case following at present:
Case 1: certain man 34 years old, suffer from erysipelas, shiver, generate heat, have a headache.Oral medicine of the present invention, each 10 milliliters, every day 3 times, above symptom was alleviated in 3 days, eliminated in 15 days.Paying a return visit after 6 months does not have recurrence.
Case 2: certain man 47 years old, suffer from erysipelas, fear of cold, scorching hot, pain.Once took the Chinese medicine of multiple treatment erysipelas, but effect is all not good.External medicine of the present invention is smeared whole body and head, and every day 2 times, each 10 milliliters, repeatedly smear at the head place.Above symptom was alleviated in 2 days, eliminated in 12 days.Paying a return visit after 12 months does not have recurrence.
Case 3: certain man 58 years old, suffer from erysipelas, scorching hot, tenderness, regional glandular enlargement.Once took the Chinese medicine of multiple treatment erysipelas, but effect is all not good.Oral medicine of the present invention, each 10 milliliters, every day 3 times; This medicine of external is smeared whole body and head, and every day 2 times, each 10 milliliters, repeatedly smear at the head place.Above symptom is oral to be alleviated with external in 1 day, eliminated in 10 days.Paying a return visit after 12 months does not have recurrence.
The specific embodiment
Embodiment 1
Take by weighing 15 parts of Flos Rosae Rugosaes, 18 parts of CitrusaurantiumL.Var.amara Engl.s, 18 parts of Herba Taraxacis, 16 parts of Flos Chrysanthemi Indicis, 15 parts of Folium Isatidiss, 17 parts of Herba Violaes, 17 parts of Rhizoma Paridis, 18 parts of Radix Trichosanthis, 19 parts of Radix Paeoniae Rubra adopt the method that decocts the back concentrating under reduced pressure to process Chinese medicine extract respectively, and are subsequent use.
Under the room temperature, get the deionized water of 5 ~ 6 times of amounts, add content and be 18 parts of 96% edible ethanols, be mixed with aqueous solution of alcohol, subsequent use.
Above-mentioned various Chinese medicine extract are added in the aqueous solution of alcohol, fully stirred 120 minutes, precipitate 2 ~ 4 hours, supernatant 200 orders filter, and the medicine that gained filtrating is the treatment erysipelas of oral administration or external carries out fill under aseptic condition.Gained precipitate and filtering residue focus on.
Embodiment 2
The drug component proportioning is: 18 parts of Flos Rosae Rugosaes, and 19 parts of CitrusaurantiumL.Var.amara Engl.s, 18 parts of Herba Taraxacis, 18 parts of Flos Chrysanthemi Indicis, 19 parts of Folium Isatidiss, 20 parts of Herba Violaes, 19 parts of Rhizoma Paridis, 18 parts of Radix Trichosanthis, 18 parts of Radix Paeoniae Rubra, content are 18 parts of 97% edible ethanols.Other is identical with embodiment 1.
Embodiment 3
The drug component proportioning is: 19 parts of Flos Rosae Rugosaes, and 20 parts of CitrusaurantiumL.Var.amara Engl.s, 20 parts of Herba Taraxacis, 19 parts of Flos Chrysanthemi Indicis, 19 parts of Folium Isatidiss, 20 parts of Herba Violaes, 19 parts of Rhizoma Paridis, 20 parts of Radix Trichosanthis, 19 parts of Radix Paeoniae Rubra, content are 18 parts of 98% edible ethanols.Other is identical with embodiment 1.
Embodiment 4
The drug component proportioning is: 16 parts of Flos Rosae Rugosaes, and 16 parts of CitrusaurantiumL.Var.amara Engl.s, 17 parts of Herba Taraxacis, 16 parts of Flos Chrysanthemi Indicis, 15 parts of Folium Isatidiss, 17 parts of Herba Violaes, 15 parts of Rhizoma Paridis, 16 parts of Radix Trichosanthis, 16 parts of Radix Paeoniae Rubra, content are 16 parts of 99% edible ethanols.Other is identical with embodiment 1.
Embodiment 5
The drug component proportioning is: 19 parts of Flos Rosae Rugosaes, and 20 parts of CitrusaurantiumL.Var.amara Engl.s, 18 parts of Herba Taraxacis, 17 parts of Flos Chrysanthemi Indicis, 18 parts of Folium Isatidiss, 19 parts of Herba Violaes, 18 parts of Rhizoma Paridis, 19 parts of Radix Trichosanthis, 17 parts of Radix Paeoniae Rubra, content are 19 parts of 100% edible ethanols.Other is identical with embodiment 1.
Embodiment 6
The drug component proportioning is: 19 parts of Flos Rosae Rugosaes, and 19 parts of CitrusaurantiumL.Var.amara Engl.s, 20 parts of Herba Taraxacis, 19 parts of Flos Chrysanthemi Indicis, 19 parts of Folium Isatidiss, 20 parts of Herba Violaes, 19 parts of Rhizoma Paridis, 19 parts of Radix Trichosanthis, 18 parts of Radix Paeoniae Rubra, content are 18 parts of 97% edible ethanols.Other is identical with embodiment 1.
Claims (1)
1. medicine of treating erysipelas is characterized in that being processed by following method:
(1) take by weighing 15 parts of Flos Rosae Rugosaes, 18 parts of CitrusaurantiumL.Var.amara Engl.s, 18 parts of Herba Taraxacis, 16 parts of Flos Chrysanthemi Indicis, 15 parts of Folium Isatidiss, 17 parts of Herba Violaes, 17 parts of Rhizoma Paridis, 18 parts of Radix Trichosanthis, 19 parts of Radix Paeoniae Rubra adopt the method that decocts the back concentrating under reduced pressure to process Chinese medicine extract respectively, and are subsequent use;
(2) under the room temperature, get the deionized water of 5 ~ 6 times of amounts, add content and be 18 parts of 96% edible ethanols, be mixed with aqueous solution of alcohol, subsequent use;
(3) above-mentioned various Chinese medicine extract are added in the aqueous solution of alcohol, fully stirred 120 minutes, precipitate 2 ~ 4 hours, supernatant 200 orders filter, and the medicine that gained filtrating is the treatment erysipelas of for oral administration or external carries out fill under aseptic condition.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010102649282A CN101987159B (en) | 2010-08-27 | 2010-08-27 | Medicine for treating erysipelas and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010102649282A CN101987159B (en) | 2010-08-27 | 2010-08-27 | Medicine for treating erysipelas and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101987159A CN101987159A (en) | 2011-03-23 |
| CN101987159B true CN101987159B (en) | 2012-07-25 |
Family
ID=43744078
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010102649282A Expired - Fee Related CN101987159B (en) | 2010-08-27 | 2010-08-27 | Medicine for treating erysipelas and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101987159B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103385981A (en) * | 2013-07-31 | 2013-11-13 | 钱家美 | Medicament for treating erysipelas, and preparation method thereof |
| CN105168772A (en) * | 2015-09-08 | 2015-12-23 | 北源生物医药研究所 | Medicine for treating erysipelas |
-
2010
- 2010-08-27 CN CN2010102649282A patent/CN101987159B/en not_active Expired - Fee Related
Non-Patent Citations (7)
| Title |
|---|
| 南京中医药大学.玫瑰花 |
| 南京中医药大学.玫瑰花;玳玳花.《中药大辞典》.上海科学技术出版社,2006,1745-1748,2098. * |
| 张兆旺，等.中药合剂（含口服液） |
| 张兆旺,等.中药合剂(含口服液)渗透促进剂.《中药药剂学》.中国中医药出版社,2002,103-105,185-187. * |
| 张金鼎.解毒清热汤.《中医急症方剂手册》.中医古籍出版社,1999,117-118. * |
| 渗透促进剂.《中药药剂学》.中国中医药出版社,2002,103-105，185-187. |
| 玳玳花.《中药大辞典》.上海科学技术出版社,2006,1745-1748，2098. |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101987159A (en) | 2011-03-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101904977B (en) | Medicament for treating mastitis and preparation method thereof | |
| CN101987166B (en) | Medicament for treating stye and preparation method thereof | |
| CN101972446B (en) | Medicament for treating coronary disease and preparation method thereof | |
| CN101983689B (en) | Drug for treating prostatitis and preparation method thereof | |
| CN101987159B (en) | Medicine for treating erysipelas and preparation method thereof | |
| CN101987125B (en) | Medicine for treating verruca plana and preparation method thereof | |
| CN101987135B (en) | Medicine for treating tetanus and preparation method thereof | |
| CN101987132B (en) | Medicament for treating acne and preparation method thereof | |
| CN101987156B (en) | Medicine for treating toothache and preparation method thereof | |
| CN101912498B (en) | Medicament for treating gout and preparation method thereof | |
| CN104587219A (en) | Traditional Chinese medicine for treating functional uterine bleeding | |
| CN104352880A (en) | Pharmaceutical composition for treating bacterial infectious cold of dogs and preparation method of pharmaceutical composition | |
| CN101987180B (en) | Medicine for treating dermatitis medicamentosa and preparation method thereof | |
| CN101987147B (en) | Medicament for treating eczema and preparation method thereof | |
| CN102370853A (en) | Traditional Chinese medicine for treating chronic pyelonephritis | |
| CN103127320B (en) | Itching relieving and anti-allergic Chinese medicinal compound umbilical patch | |
| CN105561270A (en) | Analgesic Chinese herbal medicine for external application and preparation method thereof | |
| CN104645082A (en) | Capsule for treating hepatitis and preparation method thereof | |
| CN101904962B (en) | Medicament for treating cold and preparation method thereof | |
| CN102205057B (en) | Preparation method of traditional Chinese medicine for treating conjunctival congestion type infant influenza | |
| CN101912584A (en) | Medicine for treating melancholia and preparation method thereof | |
| CN101254241A (en) | Wart eliminating and healing mixture | |
| CN104997949A (en) | Traditional Chinese medicine for treating rhinitis and preparation method thereof | |
| CN101972371B (en) | Medicament for treating hemicrania and preparation method thereof | |
| CN104784567B (en) | A kind of pharmaceutical composition for the treatment of urinary system infection |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120725 Termination date: 20180827 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |