CN101987166B - Medicament for treating stye and preparation method thereof - Google Patents
Medicament for treating stye and preparation method thereof Download PDFInfo
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- CN101987166B CN101987166B CN2010102649263A CN201010264926A CN101987166B CN 101987166 B CN101987166 B CN 101987166B CN 2010102649263 A CN2010102649263 A CN 2010102649263A CN 201010264926 A CN201010264926 A CN 201010264926A CN 101987166 B CN101987166 B CN 101987166B
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Abstract
The invention discloses a medicament for treating stye, which is characterized by mainly being prepared from the following raw materials in parts by weight: 1-20 parts of rose, 1-20 parts of seville orange flower, 1-20 parts of angelica longicaudata, 1-20 parts of thunberg fritillary bulb, 1-20 parts of radix sophorae flavescentis, 1-20 parts of honeysuckle, 1-20 parts of dried orange peel, 1-20 parts of liquorice and 1-20 parts of more than 95 percent of edible ethanol. The medicament can be absorbed by spleen and stomach through oral administration, absorbed by skin by external application and compositely absorbed in two ways of oral administration and external application. The medicament has the advantages of reasonable prescription, precise and simple matching, obvious curative effect and treatment focusing on relieving both the secondary and primary symptoms. The invention also provides a preparation method of the medicament.
Description
Technical field
The invention belongs to the field of Chinese medicines, medicine of the treatment hordeolum of particularly a kind of oral administration or external and preparation method thereof.
Background technology
Hordeolum has another name called hordeolum, is the acute suppurative inflammation of eyelid gland, and traditional medicine is called stye or hordeolum.Hordeolum shows as eyelid has little furuncle, little itching, local red and swollen, heat, bitterly, when little furuncle is ripe; Diabrosis is suppurated voluntarily; The traditional Chinese medical science thinks that the evil surfeit of affection due to external wind and heat poison is pungent, and taste accumulate long-pending pyretic toxicity, attacks on the pyretic toxicity and causes a disease; With local red and swollen, pain, scleroma and yellow pus point occurring is main clinical manifestation.This is sick obstinate, and easy relapse, can leave over a face cicatrix when serious.Hordeolum is divided into external sty and internal hordeolum.
The Chinese medicine product of existing treatment hordeolum is too much paid attention to regulating, and used taste of Chinese medicine number is too much, has reduced the medicine proportion of a therapeutical effect relatively, has influenced the pharmic function performance, so effect is slow, the course of treatment is long, and effect is undesirable.And existing Chinese medicine oral administration but can not external, but can not the taking orally again of external, route of administration is single, makes the patient slow to the absorption of medicine.Chinese medicine for oral administration not only absorbs slowly, and causes spleen injury easily, even increase the weight of the state of an illness for the patient of weakness of the spleen and stomach.
Chinese medicine is taken difficulty owing to the decoction or the pill that are mostly to boil than Western medicine, has also influenced the popularization of Chinese medicine widely.
Summary of the invention
The objective of the invention is to overcome the defective that prior art exists; A kind of reasonable recipe is provided; Compatibility is simplified, the medicine of the treatment hordeolum of determined curative effect, treating both the principal and secondary aspects of a disease, is main to control, and controls to support to combine; And this medicine can take orally through taste absorb again can external through skin absorbs, can also oral administration and externally used dual mode composite absorbent.This compound administering mode helps the efficient absorption of human body to medicine, and for the crowd of weakness of the spleen and stomach, the medicine that is busy with one's work, spares oneself provides multiple choices, especially the patient by the modern job crowd is accepted.
Technical scheme of the present invention is following:
A kind of medicine of treating hordeolum is characterized in that it mainly is to be processed by the raw material of following weight portion: 1 ~ 20 part of Flos Rosae Rugosae, 1 ~ 20 part of CitrusaurantiumL.Var.amara Engl.; 1 ~ 20 part of Radix Angelicae Sinensis, 1 ~ 20 part of Bulbus Fritillariae Thunbergii, 1 ~ 20 part of Radix Sophorae Flavescentis; 1 ~ 20 part of Flos Lonicerae; 1 ~ 20 part of Pericarpium Citri Reticulatae, 1 ~ 20 part in Radix Glycyrrhizae, content is 1 ~ 20 part of edible ethanol more than 95%.
Further, the consumption of each component of medicine of the present invention is: 15 ~ 20 parts of Flos Rosae Rugosaes, 15 ~ 20 parts of CitrusaurantiumL.Var.amara Engl.s, 15 ~ 20 parts of Radix Angelicae Sinensis; 15 ~ 20 parts of Bulbus Fritillariae Thunbergiis, 15 ~ 20 parts of Radix Sophorae Flavescentiss, 15 ~ 20 parts of Flos Loniceraes; 15 ~ 20 parts of Pericarpium Citri Reticulataes, 15 ~ 20 parts in Radix Glycyrrhizae, content is 15 ~ 20 parts of edible ethanols more than 95%.
The middle survival dose of above compatibility is the crude drug amount.
In order to strengthen the transdermal effect of medicine, can also mix transdermal agent in the medicine of the present invention, preferably weight portion is 1 ~ 5 part a azone.
Another object of the present invention provides manufacturing method for above mentioned medicine, it is characterized in that comprising the following steps:
A) take by weighing Flos Rosae Rugosae, CitrusaurantiumL.Var.amara Engl., Radix Angelicae Sinensis, Bulbus Fritillariae Thunbergii, Radix Sophorae Flavescentis, Flos Lonicerae, Pericarpium Citri Reticulatae and the Radix Glycyrrhizae of said weight proportion, according to the conventional method for distilling of Chinese medicine, the extract of the former medicine that obtains respectively respectively to distinguish the flavor of;
B) under the room temperature, get the deionized water of 5 ~ 6 times of amounts, the content that adds said weight proportion is the edible ethanol more than 95%, is mixed with aqueous solution of alcohol;
C) with in the above-mentioned aqueous solution of alcohol of the extract obtained adding of step a, stirred 120 minutes, precipitate 2 ~ 4 hours, filter, gained filtrating sterilization, fill according to quantity must be treated the medicine of hordeolum.
Further, among the step c, can add in the aqueous solution of alcohol together by azone step a is extract obtained and 1 ~ 5 weight portion.
The conventional method for distilling of said Chinese crude drug can adopt decocting method, circumfluence method, infusion process, percolation, semi-bionic extraction, supercritical fluid extraction, microwave extraction method etc. according to the kind of medical material.
The present invention is directed to the characteristics of hordeolum, select Flos Rosae Rugosae, CitrusaurantiumL.Var.amara Engl., Radix Angelicae Sinensis, Bulbus Fritillariae Thunbergii, Radix Sophorae Flavescentis, Flos Lonicerae, Pericarpium Citri Reticulatae, Radix Glycyrrhizae for use,, process to contain pure Chinese medicine extraction liquid being that edible ethanol more than 95% mixes with content after each flavor Chinese medicine extraction.Employing is main to control, and control the bonded method of supporting, but not only also external of oral administration of the medicine of processing is a kind of reasonable recipe, and compatibility is simplified, the medicine of the treatment hordeolum of determined curative effect, treating both the principal and secondary aspects of a disease.
The Radix Angelicae Sinensis blood circulation promoting and blood stasis dispelling.The Bulbus Fritillariae Thunbergii removing heat-phlegm, powder detoxifcation; Control the cough due to pathogenic wind-heat, lung abscess sore throat, scrofula, sore swollen toxin.The Radix Sophorae Flavescentis heat clearing away, dampness, parasite killing is controlled toxic-heat and blood stasis, discharging fresh blood stool, jaundice etc.The Flos Lonicerae nature and flavor are sweet, and are cold, go into lung, stomach warp; Heat clearing away, detoxifcation.Pericarpium Citri Reticulatae is warm in nature, bitter in the mouth, suffering; Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.The Radix Glycyrrhizae nature and flavor are sweet, and are flat, go into spleen, stomach, lung meridian; With middle emergency, lung moistening, detoxifcation, coordinating the actions of various ingredients in a prescription.
Radix Angelicae Sinensis blood circulation promoting and blood stasis dispelling in the medicine of the present invention; Bulbus Fritillariae Thunbergii heat clearing away eliminating stagnation; Radix Sophorae Flavescentis is let out the damp and hot of Liver Channel clearly; Flos Lonicerae, the Radix Glycyrrhizae heat-clearing and toxic substances removing; The Pericarpium Citri Reticulatae circulation of qi promoting, the merit of heat-clearing and toxic substances removing, promoting flow of QI and blood is instrumental ensembled by full side.With imitating repeatly, its effect is out of the ordinary repeatly.
Flos Rosae Rugosae regulate the flow of vital energy resolving depression and blood dissipating blood stasis; The CitrusaurantiumL.Var.amara Engl. the chest stuffiness relieving of regulating the flow of vital energy, dispersing the stagnated liver-QI for regulating the stomach, appetizing preventing or arresting vomiting.Two medicines, 5 usefulness, a gas one blood, QI and blood is two to be transferred, eliminating turbid pathogen with aromatics, the appetizing of being amusing, the strength enhancing that absorbs the drug when oral.Content is the edible ethanol blood circulation promoting and blood stasis dispelling more than 95%, promotes that drug osmotic to cell absorbs, and auxiliary taste absorb to improve curative effect when oral; Outer time spent skin expansion pore is to strengthen the drug transdermal trap.
Medicine of the present invention can also be smeared the affected part with medicine of the present invention except for oral administration, and the efficacy of a drug sick institute that goes directly so can remove the patient suffering, obtains and imitates in no time.This medicine is applicable to that also whole body smears.Adopt oral administration and externally usedly, drug effect is more remarkable.
It is obvious that the present invention treats the hordeolum curative effect, and clinical usefulness repeatly, effect are very prompt.Medicine of the present invention is through clinical 80 routine patients' clinical verification, and curing number is 48 examples, and significant figure is 24 examples, and invalid number is 8 examples, and total effective rate reaches 90%.Do not see toxic side effect in the therapeutic process.
For further specifying therapeutic effect, to enumerate model case following at present:
Case 1: certain man 19 years old, eye length has hordeolum, local red and swollen, the pain of eyelid.Oral medicine of the present invention, each 10 milliliters, every day 3 times, above symptom was alleviated in 3 days, eliminated in 18 days.Paying a return visit after 12 months does not have recurrence.
Case 2: certain man 25 years old, local scleroma, the hordeolum of occurring of eyelid.External medicine of the present invention is smeared portion and whole body near the eyes, every day 2 times, each 10 milliliters, locates near the eyes repeatedly to smear.Above symptom was alleviated in 2 days, eliminated in 13 days.Paying a return visit after 12 months does not have recurrence.
Case 3: certain man 28 years old, local yellow suppuration point, obvious, the tenderness of edema of occurring of eyelid.Oral medicine of the present invention, each 10 milliliters, every day 3 times; This medicine of external is smeared portion and whole body near the eyes, every day 2 times, each 10 milliliters, locates near the eyes repeatedly to smear.Above symptom is oral to be alleviated after 1 day with external, eliminates in 10 days.Paying a return visit after 12 months does not have recurrence.
The specific embodiment
Embodiment 1
Take by weighing 15 parts of Flos Rosae Rugosaes, 18 parts of CitrusaurantiumL.Var.amara Engl.s, 20 parts of Radix Angelicae Sinensis, 16 parts of Bulbus Fritillariae Thunbergiis, 16 parts of Radix Sophorae Flavescentiss, 18 parts of Flos Loniceraes, 17 parts of Pericarpium Citri Reticulataes, 17 parts in Radix Glycyrrhizae adopts the method that decocts the back concentrating under reduced pressure to process Chinese medicine extract respectively, and is subsequent use.
Under the room temperature, get the deionized water of 5 ~ 6 times of amounts, add content and be 18 parts of 96% edible ethanols, be mixed with aqueous solution of alcohol, subsequent use.
Above-mentioned various Chinese medicine extract are added in the aqueous solution of alcohol, fully stirred 120 minutes, precipitate 2 ~ 4 hours, supernatant 200 orders filter, and the medicine that gained filtrating is the treatment hordeolum of oral administration or external carries out fill under aseptic condition.Gained precipitate and filtering residue focus on.
Embodiment 2
The drug component proportioning is: 18 parts of Flos Rosae Rugosaes, and 19 parts of CitrusaurantiumL.Var.amara Engl.s, 20 parts of Radix Angelicae Sinensis, 19 parts of Bulbus Fritillariae Thunbergiis, 18 parts of Radix Sophorae Flavescentiss, 18 parts of Flos Loniceraes, 18 parts of Pericarpium Citri Reticulataes, 18 parts in Radix Glycyrrhizae, content is 18 parts of 97% edible ethanols.Other is identical with embodiment 1.
Embodiment 3
The drug component proportioning is: 19 parts of Flos Rosae Rugosaes, and 20 parts of CitrusaurantiumL.Var.amara Engl.s, 19 parts of Radix Angelicae Sinensis, 18 parts of Bulbus Fritillariae Thunbergiis, 20 parts of Radix Sophorae Flavescentiss, 18 parts of Flos Loniceraes, 19 parts of Pericarpium Citri Reticulataes, 19 parts in Radix Glycyrrhizae, content is 18 parts of 98% edible ethanols.Other is identical with embodiment 1.
Embodiment 4
The drug component proportioning is: 16 parts of Flos Rosae Rugosaes, and 15 parts of CitrusaurantiumL.Var.amara Engl.s, 16 parts of Radix Angelicae Sinensis, 17 parts of Bulbus Fritillariae Thunbergiis, 18 parts of Radix Sophorae Flavescentiss, 16 parts of Flos Loniceraes, 15 parts of Pericarpium Citri Reticulataes, 15 parts in Radix Glycyrrhizae, content is 16 parts of 99% edible ethanols.Other is identical with embodiment 1.
Embodiment 5
The drug component proportioning is: 17 parts of Flos Rosae Rugosaes, and 18 parts of CitrusaurantiumL.Var.amara Engl.s, 17 parts of Radix Angelicae Sinensis, 18 parts of Bulbus Fritillariae Thunbergiis, 17 parts of Radix Sophorae Flavescentiss, 20 parts of Flos Loniceraes, 18 parts of Pericarpium Citri Reticulataes, 20 parts in Radix Glycyrrhizae, content is 19 parts of 100% edible ethanols.Other is identical with embodiment 1.
Embodiment 6
The drug component proportioning is: 19 parts of Flos Rosae Rugosaes, and 20 parts of CitrusaurantiumL.Var.amara Engl.s, 20 parts of Radix Angelicae Sinensis, 19 parts of Bulbus Fritillariae Thunbergiis, 20 parts of Radix Sophorae Flavescentiss, 20 parts of Flos Loniceraes, 20 parts of Pericarpium Citri Reticulataes, 18 parts in Radix Glycyrrhizae, content is 20 parts of 97% edible ethanols.Other is identical with embodiment 1.
Claims (1)
1. medicine of treating hordeolum is characterized in that being processed by following method:
(1) take by weighing 15 parts of Flos Rosae Rugosaes, 18 parts of CitrusaurantiumL.Var.amara Engl.s, 20 parts of Radix Angelicae Sinensis, 16 parts of Bulbus Fritillariae Thunbergiis, 16 parts of Radix Sophorae Flavescentiss, 18 parts of Flos Loniceraes, 17 parts of Pericarpium Citri Reticulataes, 17 parts in Radix Glycyrrhizae adopts the method that decocts the back concentrating under reduced pressure to process Chinese medicine extract respectively, and is subsequent use;
(2) under the room temperature, get the deionized water of 5 ~ 6 times of amounts, add content and be 18 parts of 96% edible ethanols, be mixed with aqueous solution of alcohol, subsequent use;
(3) above-mentioned various Chinese medicine extract are added in the aqueous solution of alcohol, fully stirred 120 minutes, precipitate 2 ~ 4 hours, supernatant 200 orders filter, and the medicine that gained filtrating is the treatment hordeolum of for oral administration or external carries out fill under aseptic condition.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010102649263A CN101987166B (en) | 2010-08-27 | 2010-08-27 | Medicament for treating stye and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2010102649263A CN101987166B (en) | 2010-08-27 | 2010-08-27 | Medicament for treating stye and preparation method thereof |
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| Publication Number | Publication Date |
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| CN101987166A CN101987166A (en) | 2011-03-23 |
| CN101987166B true CN101987166B (en) | 2012-07-25 |
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| CN2010102649263A Expired - Fee Related CN101987166B (en) | 2010-08-27 | 2010-08-27 | Medicament for treating stye and preparation method thereof |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103006949A (en) * | 2012-11-29 | 2013-04-03 | 董德华 | Medicinal composition for treating stye |
| CN103191230B (en) * | 2013-03-07 | 2014-04-02 | 丁美松 | Traditional Chinese medicine for treating infantile recurrent hordeolum |
| CN105213873A (en) * | 2015-11-10 | 2016-01-06 | 刘彦标 | A kind of Chinese medicine and western medicine compound external-use preparation being used for the treatment of hordeolum |
| CN105833095A (en) * | 2016-05-24 | 2016-08-10 | 柳晖 | Traditional Chinese medicine composition for treating hordeolum |
| CN105816645A (en) * | 2016-06-03 | 2016-08-03 | 陈瑞 | Drops for treating palpebral abscess |
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| CN1159936A (en) * | 1997-01-08 | 1997-09-24 | 丁明月 | Medicine for preventing and treating eye diseases |
| CN1165686A (en) * | 1997-01-21 | 1997-11-26 | 杨沅江 | Medicinal cream for treating sore and its prepn. method |
| CN1207322A (en) * | 1998-08-19 | 1999-02-10 | 刘毅刚 | Eye drops for treating conjunctivitis and preparing process thereof |
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2010
- 2010-08-27 CN CN2010102649263A patent/CN101987166B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1159936A (en) * | 1997-01-08 | 1997-09-24 | 丁明月 | Medicine for preventing and treating eye diseases |
| CN1165686A (en) * | 1997-01-21 | 1997-11-26 | 杨沅江 | Medicinal cream for treating sore and its prepn. method |
| CN1207322A (en) * | 1998-08-19 | 1999-02-10 | 刘毅刚 | Eye drops for treating conjunctivitis and preparing process thereof |
Non-Patent Citations (3)
| Title |
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| 廖华.解毒法在眼科临床的运用.《中国中医眼科杂志》.1994,第4卷(第3期),177-180. * |
| 聂亚飞,等.中药内服熏洗治疗睑缘炎50例.《辽宁中医杂志》.1994,第21卷(第5期),219. * |
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Granted publication date: 20120725 Termination date: 20180827 |