CN101904417A - Antibiotic complex aquatic feed additive and mixed feed thereof - Google Patents
Antibiotic complex aquatic feed additive and mixed feed thereof Download PDFInfo
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- CN101904417A CN101904417A CN 201010234796 CN201010234796A CN101904417A CN 101904417 A CN101904417 A CN 101904417A CN 201010234796 CN201010234796 CN 201010234796 CN 201010234796 A CN201010234796 A CN 201010234796A CN 101904417 A CN101904417 A CN 101904417A
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Abstract
The invention discloses an antibiotic complex aquatic feed additive which is prepared from the following components in percentage by weight: 1-2 percent of probiotics, 8-9 percent of prebiotics and 20-30 percent of carriers. The probiotics comprise natto bacillus, bacillus coagulans and clostridium freeze-dried powder, the prebiotics comprise xylo-oligosaccharide, ganoderma meat amylase and oligochitosan, and the carriers comprise montmorillonite and corn starch. The antibiotic complex aquatic feed additive not only has the advantages of stable thalli and long survival time, but also has the effectiveness of united multiple roles. the invention also provides a mixed feed containing the antibiotic complex aquatic feed additive, which can obviously improve the digestion function of animals, increase the growth performance of animals of fishes, shrimps, soft-shelled turtles, and the like, decrease the feed factor, enhance the immunity of the animals and obviously improve the meat quality of animals.
Description
Technical field
The present invention relates to feeding additive aquatic animal, particularly a kind of antibiotic complex aquatic feed addictive and mixed fodder thereof that contains profitable probliotics, prebiotics and carrier.
Background technology
Fishing is promoting aquatic animal growth, prevent disease, is improving feed coefficient, is ensureing that aspects such as health have a significant effect, and have greatly improved the economic benefit of culture fishery with antibiotic.Yet, use for a long time and abuse of antibiotics, brought such as all adverse consequences such as drug resistance, medicament residue, little disruption of ecological balance, animal body immunity degradation, this will have a strong impact on the safety of aquatic products and human healthy.Many in the world countries take to forbid or limit the measure of using chemical synthetic drug additives such as antibiotic gradually at present, and then guarantee the sustainable development of culture fishery.Therefore, development and development of new, non-harmful antibiotic substitute has been extremely urgent, this also is the industrial urgent problem of aquatic feeds.
Studies have shown that antibiotic growth enhancing effect mainly is to come from the influence of antibiotic to the little ecology of animal alimentary canal, these research and development for the antibiotic substitute provide new thinking.In recent years, probio is as novel green feed additive, and the biological competition repulsive interaction by animal alimentary canal forms dominant microflora or strengthens immunity of organism and comes prevent disease, promotes growth of animal and improves feed coefficient, has obtained significant effect.But actual production and use in exist many distinct issues, low such as survival rate, the poor stability of the single and thalline of thalline effect, in fact this has been the bottleneck of the extensive industrialization of restriction probiotics preparation.
Summary of the invention
The objective of the invention is to overcome deficiency of the prior art, a kind of antibiotic complex aquatic feed addictive is provided, this feeding additive aquatic animal not only has the characteristics that thalline is stable, the time-to-live is long, and has associating multiple action effect.
A kind of antibiotic complex aquatic feed addictive comprises probio, prebiotics and carrier, it is characterized in that, the mass ratio of probio, prebiotics and carrier is 1～2: 8～9: 20～30; Described probio is made up of bafillus natto, bacillus coagulans and clostridium butyricum freeze-dried powder; Described prebiotics is made up of xylo-oligosaccharide, Ganoderma lucidum polysaccharide and chitosan oligomer; Described carrier is made up of montmorillonite and cornstarch.
Further, the mass ratio of bafillus natto, bacillus coagulans and clostridium butyricum freeze-dried powder is 1～2 in the probio: 6～8: 1～2.
Further, the mass ratio of xylo-oligosaccharide, Ganoderma lucidum polysaccharide and chitosan oligomer is 3～5 in the prebiotics: 1: 3～5.
The mass ratio of montmorillonite and cornstarch is 1～2 in the carrier: 1.
Each component of additive of the present invention is mixed in the following order: 30% carrier and prebiotics are mixed, add 30% carrier and mix, add probio again and mix, add 40% carrier at last and mix.
The present invention utilizes probio and prebiotics to form Synbiotics, and the carrier appendix of forming with montmorillonite and cornstarch, on the one hand the needed selectivity substrate of probio is more easily obtained, thereby improve the survival rate of beneficial bacterium, and growth of the beneficial bacterium of the characteristic selective stimulating host who utilizes prebiotics own and breeding, thereby give full play to the two joint effect.Be the protective effect that utilizes montmorillonite and cornstarch on the other hand, not only prolonged the time-to-live of probio, and montmorillonite itself also has special biological effect.By the associating multiple action effect of probio, prebiotics and three levels of carrier, finally reach the purpose that promotes host health.
Another object of the present invention is to provide the mixed fodder that contains above-mentioned antibiotic complex aquatic additive, it is characterized in that, described mixed fodder comprises antibiotic complex aquatic additive and common aquatic feeds, and wherein to make an addition to the percentage by weight of common aquatic feeds be 0.1%～0.5% to the antibiotic complex aquatic additive.
Is 0.1%～0.5% to add in the aquatic feeds the antibiotic complex aquatic feed addictive according to percentage by weight, can significantly improve the digestive function of animal, improve the growth performance of animals such as culturing fish, shrimp, soft-shelled turtle, reduce feed coefficient, and can improve the animal immune ability, significantly improve the meat of animal.
The specific embodiment
Embodiment 1
The antibiotic complex aquatic feed addictive is made with following method: bafillus natto, bacillus coagulans and clostridium butyricum freeze-dried powder mix as probio standby according to mass ratio at 1: 8: 1; Xylo-oligosaccharide, Ganoderma lucidum polysaccharide and chitosan oligomer mix as prebiotics standby according to quality ratio at 4: 1: 5; Montmorillonite and cornstarch mix as carrier standby according to mass ratio at 1: 1.
With probio: prebiotics: carrier is 1: 9: 20 a quality ratio, mix in the following order: 30% carrier and prebiotics are mixed, adding 30% carrier mixes, adding probio again mixes, add 40% carrier at last and mix, make the antibiotic complex aquatic feed addictive.
Is 0.5% to be added in the soft-shelled turtle aquatic feeds feeding soft-shelled turtle with above-mentioned antibiotic complex aquatic feed addictive according to percentage by weight.
Feeding experiment result shows, compares with control group, and the soft-shelled turtle survival rate has improved 18.4%, and average yield per mu has improved 11.7%, and feed coefficient has reduced by 10.5%, and economic benefit has increased by 13.7%.
Embodiment 2
The antibiotic complex aquatic feed addictive is made with following method: bafillus natto, bacillus coagulans and clostridium butyricum freeze-dried powder mix as probio standby according to mass ratio at 2: 6: 2; Xylo-oligosaccharide, Ganoderma lucidum polysaccharide and chitosan oligomer mix as prebiotics standby according to quality ratio at 5: 1: 4; Montmorillonite and cornstarch mix as carrier standby according to mass ratio at 2: 1.
With probio: prebiotics: carrier is 2: 8: 30 a quality ratio, mix in the following order: 30% carrier and prebiotics are mixed, adding 30% carrier mixes, adding probio again mixes, add 40% carrier at last and mix, make the antibiotic complex aquatic feed addictive.
Is 0.2% to be added in the Penaeus Vannmei aquatic feeds feeding prawn with above-mentioned antibiotic complex aquatic feed addictive according to percentage by weight.
Feeding experiment result shows, compares with control group, and the prawn daily gain has improved 15.73%, and feed coefficient has reduced by 8.42%, and survival rate has improved 19.03%, and economic benefit has increased by 17.55%.Quality to prawn is carried out further check and analysis, and the result shows that crude fat content significantly descends in the meat, has reduced by 5.38%, and crude protein, coarse ash and moisture do not have marked change.
Embodiment 3
The antibiotic complex aquatic feed addictive is made with following method: bafillus natto, bacillus coagulans and clostridium butyricum freeze-dried powder mix as probio standby according to mass ratio at 2: 7: 1; Xylo-oligosaccharide, Ganoderma lucidum polysaccharide and chitosan oligomer mix as prebiotics standby according to quality ratio at 3: 1: 4; Montmorillonite and cornstarch mix as carrier standby according to mass ratio at 1: 1.
With probio: prebiotics: carrier is 2: 8: 20 a quality ratio, mix in the following order: 30% carrier and prebiotics are mixed, adding 30% carrier mixes, adding probio again mixes, add 40% carrier at last and mix, make the antibiotic complex aquatic feed addictive.
Is 0.1% to be added in the hybridized prussian carp aquatic feeds feeding hybridized prussian carp with above-mentioned antibiotic complex aquatic feed addictive according to percentage by weight.
Feeding experiment result shows, compares with control group, and the hybridized prussian carp daily gain has improved 10.2%, and survival rate has improved 13.5%, and economic benefit has increased by 9.4%.Quality to crucian is carried out further check and analysis, and the result shows that crude fat content significantly descends in the meat, has reduced by 7.6%, and conventional indexs such as other crude protein, coarse ash and moisture do not have marked change.Relatively carry out further amynologic index analysis with control group, the result shows that symphysis unit complex aquatic feed addictive has significantly improved superoxide dismutase activity in haemocyte respiratory burst activity and the serum, has improved 202.33% and 52.33% respectively.
Embodiment 4
The antibiotic complex aquatic feed addictive is made with following method: bafillus natto, bacillus coagulans and clostridium butyricum freeze-dried powder mix as probio standby according to mass ratio at 1: 8: 1; Xylo-oligosaccharide, Ganoderma lucidum polysaccharide and chitosan oligomer mix as prebiotics standby according to quality ratio at 3: 1: 4; Montmorillonite and cornstarch mix as carrier standby according to mass ratio at 1: 1.
With probio: prebiotics: carrier is 1: 9: 20 a quality ratio, mix in the following order: 30% carrier and prebiotics are mixed, adding 30% carrier mixes, adding probio again mixes, add 40% carrier at last and mix, make the antibiotic complex aquatic feed addictive.
Is 0.2% to be added in the perch aquatic feeds above-mentioned antibiotic complex aquatic feed addictive according to percentage by weight.
Feeding experiment result shows, compares with control group, and the perch daily gain has improved 11.8%, and survival rate has improved 10.2%, and economic benefit has increased by 10.2%.Further amynologic index the analysis showed that, all increases significantly with complement C3 content and serum activity of myeloperoxidase in the control group comparison serum, has improved 121.4% and 184.5% respectively.
At last, it is also to be noted that what more than enumerate only is several specific embodiments of the present invention.Obviously, the invention is not restricted to above embodiment, many distortion can also be arranged.All distortion that those of ordinary skill in the art can directly derive or associate from content disclosed by the invention all should be thought protection scope of the present invention.
Claims (5)
1. an antibiotic complex aquatic feed addictive comprises probio, prebiotics and carrier, it is characterized in that, the mass ratio of probio, prebiotics and carrier is 1～2: 8～9: 20～30; Described probio is made up of bafillus natto, bacillus coagulans and clostridium butyricum freeze-dried powder; Described prebiotics is made up of xylo-oligosaccharide, Ganoderma lucidum polysaccharide and chitosan oligomer; Described carrier is made up of montmorillonite and cornstarch.
2. antibiotic complex aquatic feed addictive as claimed in claim 1 is characterized in that, the mass ratio of bafillus natto, bacillus coagulans and clostridium butyricum freeze-dried powder is 1～2 in the probio: 6～8: 1～2.
3. antibiotic complex aquatic feed addictive as claimed in claim 2 is characterized in that, the mass ratio of xylo-oligosaccharide, Ganoderma lucidum polysaccharide and chitosan oligomer is 3～5 in the prebiotics: 1: 3～5.
4. antibiotic complex aquatic feed addictive as claimed in claim 3 is characterized in that the mass ratio of montmorillonite and cornstarch is 1～2 in the carrier: 1.
5. the mixed fodder that contains the described antibiotic complex aquatic additive of one of claim 1-4, it is characterized in that, described mixed fodder comprises antibiotic complex aquatic additive and common aquatic feeds, and wherein to make an addition to the percentage by weight of common aquatic feeds be 0.1%～0.5% to the antibiotic complex aquatic additive.
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| CN102077906A (en) * | 2010-12-17 | 2011-06-01 | 湖南农业大学 | High efficient compound feed additive and feed containing the same |
| CN102106482A (en) * | 2011-01-27 | 2011-06-29 | 绍兴中亚工贸园有限公司 | Feed for culturing soft-shelled turtle and processing technology thereof |
| CN102138639A (en) * | 2011-01-26 | 2011-08-03 | 龙岩新奥生物科技有限公司 | Digestion aiding compound as well as preparation method and application thereof to feed additive |
| CN102160605A (en) * | 2011-02-21 | 2011-08-24 | 杭州向天歌生物科技有限公司 | Preparation method of biological active montmorillonite powder and application of biological active montmorillonite powder serving as feed additive in feed |
| CN102511662A (en) * | 2012-01-05 | 2012-06-27 | 上海创博生态工程有限公司 | Composite probiotic microorganism feed additive, preparation method and application thereof |
| CN102919542A (en) * | 2012-11-13 | 2013-02-13 | 西华大学 | Multistage-controlled-release probiotics microecological preparation composite feed for Silurus meridionalis and preparation method thereof |
| CN103005157A (en) * | 2012-12-13 | 2013-04-03 | 安徽省正大源饲料集团有限公司 | Novel efficient synbiotics intestines-targeting microspheric capsule and preparation method thereof |
| CN103053806A (en) * | 2012-12-27 | 2013-04-24 | 深圳华大基因科技有限公司 | A synbiotic feed additive, and a preparation method and applications thereof |
| CN103392923A (en) * | 2013-07-23 | 2013-11-20 | 上海创博生态工程有限公司 | Microorganism feed additive for improving reproduction ability of animals and preparation method thereof |
| CN103404748A (en) * | 2013-09-03 | 2013-11-27 | 瑞金市香山生态科技发展有限公司 | Soft-shelled turtle feed prepared from obsolete pigs |
| CN103766610A (en) * | 2014-02-26 | 2014-05-07 | 南京华牧动物科技研究所有限公司 | Premixed feeds capable of improving growth performance and organism immunity of livestock and poultry, and preparation method and application of premixed feeds |
| CN104171421A (en) * | 2014-08-08 | 2014-12-03 | 河南牧翔动物药业有限公司 | Feed additive for conditioning intestines of animals |
| CN105325708A (en) * | 2015-12-03 | 2016-02-17 | 成都益特佳生物科技有限公司 | Nonreactive feed additive for removing mildew and treating diarrhoea and preparation method and application thereof |
| CN106417989A (en) * | 2016-02-02 | 2017-02-22 | 武汉万德瑞生物技术有限公司 | Probiotic composition for aquatic animal feed, preparation method and application thereof |
| CN106562115A (en) * | 2016-10-26 | 2017-04-19 | 宁波大学 | Marine fish microbial preparation composition and application thereof |
| CN107028026A (en) * | 2017-05-06 | 2017-08-11 | 安徽帝都农业生态园有限公司 | A kind of many effect feeding additive aquatic animals and preparation method thereof |
| CN107114559A (en) * | 2016-02-24 | 2017-09-01 | 大道东圣（天津）生物科技有限公司 | Livestock and poultry liquid additive without antibody cultivation |
| CN107410773A (en) * | 2017-09-25 | 2017-12-01 | 芜湖诚德农业科技有限公司 | A kind of soft-shelled turtle feed and preparation method thereof |
| CN109090007A (en) * | 2018-08-02 | 2018-12-28 | 魏雪珠 | A kind of light, the full ecology filtration system of seawater race fishpond shrimp ponds production method |
| CN110050880A (en) * | 2019-05-16 | 2019-07-26 | 泰州好润生物科技股份有限公司 | A kind of feeding additive aquatic animal and preparation method thereof |
| CN110651892A (en) * | 2019-11-12 | 2020-01-07 | 扬州大学 | Macrobrachium rosenbergii micro-ecological feed compound additive and application thereof |
| CN110810667A (en) * | 2019-11-25 | 2020-02-21 | 江苏昌浩水产科技有限公司 | Mixed fish feed additive |
| CN111248339A (en) * | 2020-01-01 | 2020-06-09 | 浙江省舟山市水产研究所 | Feed additive for improving meat quality of seawater culture weever, culture feed and application of feed additive |
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| CN102077906A (en) * | 2010-12-17 | 2011-06-01 | 湖南农业大学 | High efficient compound feed additive and feed containing the same |
| CN102138639A (en) * | 2011-01-26 | 2011-08-03 | 龙岩新奥生物科技有限公司 | Digestion aiding compound as well as preparation method and application thereof to feed additive |
| CN102138639B (en) * | 2011-01-26 | 2014-11-12 | 龙岩新奥生物科技有限公司 | Digestion aiding compound as well as preparation method and application thereof to feed additive |
| CN102106482A (en) * | 2011-01-27 | 2011-06-29 | 绍兴中亚工贸园有限公司 | Feed for culturing soft-shelled turtle and processing technology thereof |
| CN102160605A (en) * | 2011-02-21 | 2011-08-24 | 杭州向天歌生物科技有限公司 | Preparation method of biological active montmorillonite powder and application of biological active montmorillonite powder serving as feed additive in feed |
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| CN102919542A (en) * | 2012-11-13 | 2013-02-13 | 西华大学 | Multistage-controlled-release probiotics microecological preparation composite feed for Silurus meridionalis and preparation method thereof |
| CN103005157A (en) * | 2012-12-13 | 2013-04-03 | 安徽省正大源饲料集团有限公司 | Novel efficient synbiotics intestines-targeting microspheric capsule and preparation method thereof |
| CN103053806A (en) * | 2012-12-27 | 2013-04-24 | 深圳华大基因科技有限公司 | A synbiotic feed additive, and a preparation method and applications thereof |
| CN103392923A (en) * | 2013-07-23 | 2013-11-20 | 上海创博生态工程有限公司 | Microorganism feed additive for improving reproduction ability of animals and preparation method thereof |
| CN103404748A (en) * | 2013-09-03 | 2013-11-27 | 瑞金市香山生态科技发展有限公司 | Soft-shelled turtle feed prepared from obsolete pigs |
| CN103766610A (en) * | 2014-02-26 | 2014-05-07 | 南京华牧动物科技研究所有限公司 | Premixed feeds capable of improving growth performance and organism immunity of livestock and poultry, and preparation method and application of premixed feeds |
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| CN105325708A (en) * | 2015-12-03 | 2016-02-17 | 成都益特佳生物科技有限公司 | Nonreactive feed additive for removing mildew and treating diarrhoea and preparation method and application thereof |
| CN106417989A (en) * | 2016-02-02 | 2017-02-22 | 武汉万德瑞生物技术有限公司 | Probiotic composition for aquatic animal feed, preparation method and application thereof |
| CN107114559A (en) * | 2016-02-24 | 2017-09-01 | 大道东圣（天津）生物科技有限公司 | Livestock and poultry liquid additive without antibody cultivation |
| CN106562115A (en) * | 2016-10-26 | 2017-04-19 | 宁波大学 | Marine fish microbial preparation composition and application thereof |
| EP3609351A4 (en) * | 2017-04-10 | 2021-01-27 | Kibow Biotech, Inc. | Multifiber prebiotic composition for digestive health, weight control, boosting immunity and improving health |
| US11559554B2 (en) | 2017-04-10 | 2023-01-24 | Kibow Biotech Inc. | Multifiber prebiotic composition for digestive health, weight control, boosting immunity and improving health |
| CN107028026A (en) * | 2017-05-06 | 2017-08-11 | 安徽帝都农业生态园有限公司 | A kind of many effect feeding additive aquatic animals and preparation method thereof |
| CN107410773A (en) * | 2017-09-25 | 2017-12-01 | 芜湖诚德农业科技有限公司 | A kind of soft-shelled turtle feed and preparation method thereof |
| CN109090007A (en) * | 2018-08-02 | 2018-12-28 | 魏雪珠 | A kind of light, the full ecology filtration system of seawater race fishpond shrimp ponds production method |
| CN110050880A (en) * | 2019-05-16 | 2019-07-26 | 泰州好润生物科技股份有限公司 | A kind of feeding additive aquatic animal and preparation method thereof |
| CN110651892A (en) * | 2019-11-12 | 2020-01-07 | 扬州大学 | Macrobrachium rosenbergii micro-ecological feed compound additive and application thereof |
| CN110810667A (en) * | 2019-11-25 | 2020-02-21 | 江苏昌浩水产科技有限公司 | Mixed fish feed additive |
| CN111248339A (en) * | 2020-01-01 | 2020-06-09 | 浙江省舟山市水产研究所 | Feed additive for improving meat quality of seawater culture weever, culture feed and application of feed additive |
| CN111642620A (en) * | 2020-07-08 | 2020-09-11 | 漯河医学高等专科学校 | Compound probiotic preparation and preparation method and application thereof |
| CN115024374A (en) * | 2022-06-15 | 2022-09-09 | 黄淮学院 | Preparation method and application of candy containing immobilized probiotics |
| CN115024374B (en) * | 2022-06-15 | 2023-11-24 | 黄淮学院 | Preparation method and application of candy containing immobilized probiotics |
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Application publication date: 20101208 Assignee: RONGCHENG HUATONG OCEAN BIOTECHNOLOGY CO., LTD. Assignor: Zhejiang Gongshang University Contract record no.: 2016330000070 Denomination of invention: Antibiotic complex aquatic feed additive and mixed feed thereof Granted publication date: 20121121 License type: Common License Record date: 20160503 |
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