CN101883634A - 用于检测流体中组分的装置 - Google Patents

用于检测流体中组分的装置 Download PDF

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Publication number
CN101883634A
CN101883634A CN2008801144648A CN200880114464A CN101883634A CN 101883634 A CN101883634 A CN 101883634A CN 2008801144648 A CN2008801144648 A CN 2008801144648A CN 200880114464 A CN200880114464 A CN 200880114464A CN 101883634 A CN101883634 A CN 101883634A
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CN
China
Prior art keywords
blood
component
filter
measurement
detection reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2008801144648A
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English (en)
Chinese (zh)
Inventor
斯蒂芬·马格拉夫
马丁·舒尔茨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leukocare AG
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Leukocare AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leukocare AG filed Critical Leukocare AG
Publication of CN101883634A publication Critical patent/CN101883634A/zh
Pending legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/026Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0684Venting, avoiding backpressure, avoid gas bubbles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/046Function or devices integrated in the closure
    • B01L2300/049Valves integrated in closure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0681Filter
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B01L2400/049Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CN2008801144648A 2007-10-31 2008-10-31 用于检测流体中组分的装置 Pending CN101883634A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07021342.6 2007-10-31
EP07021342A EP2055384A1 (de) 2007-10-31 2007-10-31 Vorrichtung zum Nachweis von Bestandteilen in einem Fluid
PCT/EP2008/009219 WO2009056340A2 (de) 2007-10-31 2008-10-31 Vorrichtung zum nachweis von bestandteilen in einem fluid

Publications (1)

Publication Number Publication Date
CN101883634A true CN101883634A (zh) 2010-11-10

Family

ID=39154030

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008801144648A Pending CN101883634A (zh) 2007-10-31 2008-10-31 用于检测流体中组分的装置

Country Status (5)

Country Link
US (1) US20100261223A1 (enExample)
EP (2) EP2055384A1 (enExample)
JP (1) JP2011501201A (enExample)
CN (1) CN101883634A (enExample)
WO (1) WO2009056340A2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103323590A (zh) * 2013-06-08 2013-09-25 上海云泽生物科技有限公司 一种基于纤维膜捕集分离的定量检测装置及其检测方法
CN104053983A (zh) * 2011-09-13 2014-09-17 奥雷科有限公司 诊断仪器
CN105209880A (zh) * 2013-03-15 2015-12-30 赛拉诺斯股份有限公司 用于样品收集和样品分离的方法和装置
CN113933129A (zh) * 2021-09-14 2022-01-14 深圳大学 子痫前期诊断试剂盒以及荧光染料的应用

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DE102009045404B4 (de) * 2009-10-06 2012-04-19 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Abmesskanal und mikrofluidische Struktur und Verfahren zum Abmessen und/oder Positionieren eines Volumens einer Flüssigkeit
GB2474888A (en) * 2009-10-30 2011-05-04 Univ Dublin City Microfluidic devices with degassing driven fluid flow
RU2645091C2 (ru) * 2012-08-08 2018-02-15 Конинклейке Филипс Н.В. Способ и устройство для отделения плазмы от крови для оценки содержания билирубина
AT513559B1 (de) * 2012-11-06 2016-02-15 Gerhard Bonecker Photometrische Messeinrichtung und photometrisches Messverfahren für eine Probenflüssigkeit
US9386948B2 (en) 2012-12-05 2016-07-12 Theranos, Inc. Systems, devices, and methods for bodily fluid sample transport
US10248765B1 (en) 2012-12-05 2019-04-02 Theranos Ip Company, Llc Systems, devices, and methods for bodily fluid sample collection, transport, and handling
JP6566319B2 (ja) * 2013-12-03 2019-08-28 国立大学法人 東京大学 分離ユニット、分離方法、流体デバイス、複合型流体デバイス及びキット
CN105772117A (zh) * 2014-12-22 2016-07-20 卡梅德生物科技(天津)有限公司 一种用于生物实验室检测化学成份的实验芯片
CN104880442B (zh) * 2015-05-21 2017-10-10 桂林理工大学 一种测定盐酸多巴胺的方法
US10371606B2 (en) 2015-07-21 2019-08-06 Theraos IP Company, LLC Bodily fluid sample collection and transport
WO2017044888A1 (en) 2015-09-09 2017-03-16 Theranos, Inc. Methods and devices for sample collection and sample separation
JP6874432B2 (ja) * 2017-03-10 2021-05-19 東洋紡株式会社 イムノクロマト試験片
US11857966B1 (en) 2017-03-15 2024-01-02 Labrador Diagnostics Llc Methods and devices for sample collection and sample separation
US11287404B2 (en) * 2017-12-21 2022-03-29 International Business Machines Corporation Analysis apparatus with spectrometer

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CN1250160A (zh) * 1998-07-20 2000-04-12 生命扫描有限公司 用于医疗诊断的流体装置
WO2006009724A2 (en) * 2004-06-17 2006-01-26 Micronics, Inc. Microfluidic devices for fluid manipulation and analysis
US20060228259A1 (en) * 2005-04-12 2006-10-12 Chromodex Inc. Joint-diagnostic spectroscopic and biosensor meter
WO2007002579A2 (en) * 2005-06-23 2007-01-04 Bioveris Corporation Assay cartridges and methods for point of care instruments

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JPS544121Y2 (enExample) * 1974-07-05 1979-02-23
US4816224A (en) * 1980-08-05 1989-03-28 Boehringer Mannheim Gmbh Device for separating plasma or serum from whole blood and analyzing the same
US5186843A (en) * 1991-07-22 1993-02-16 Ahlstrom Filtration, Inc. Blood separation media and method for separating plasma from whole blood
EP0684864B1 (en) * 1993-12-22 2004-03-10 Baxter International Inc. Methods for characterizing complex filtration media
US5700695A (en) * 1994-06-30 1997-12-23 Zia Yassinzadeh Sample collection and manipulation method
EP1034040A2 (en) * 1997-11-25 2000-09-13 Mosaic Technologies Devices and methods for detecting target molecules in biological samples
JP3833830B2 (ja) * 1998-09-01 2006-10-18 富士写真フイルム株式会社 血液成分分離器
US6436121B1 (en) * 2001-04-30 2002-08-20 Paul H. Blom Removable blood filter
KR101005970B1 (ko) * 2002-11-19 2011-01-05 가부시키가이샤 아이 디자인 혈장 또는 혈청 분리막, 및 혈장 또는 혈청 분리막을이용한 필터 장치

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1250160A (zh) * 1998-07-20 2000-04-12 生命扫描有限公司 用于医疗诊断的流体装置
WO2006009724A2 (en) * 2004-06-17 2006-01-26 Micronics, Inc. Microfluidic devices for fluid manipulation and analysis
US20060228259A1 (en) * 2005-04-12 2006-10-12 Chromodex Inc. Joint-diagnostic spectroscopic and biosensor meter
WO2007002579A2 (en) * 2005-06-23 2007-01-04 Bioveris Corporation Assay cartridges and methods for point of care instruments
US20070031283A1 (en) * 2005-06-23 2007-02-08 Davis Charles Q Assay cartridges and methods for point of care instruments

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104053983A (zh) * 2011-09-13 2014-09-17 奥雷科有限公司 诊断仪器
CN105209880A (zh) * 2013-03-15 2015-12-30 赛拉诺斯股份有限公司 用于样品收集和样品分离的方法和装置
CN105209880B (zh) * 2013-03-15 2020-03-17 赛拉诺斯知识产权有限责任公司 用于样品收集和样品分离的方法和装置
CN103323590A (zh) * 2013-06-08 2013-09-25 上海云泽生物科技有限公司 一种基于纤维膜捕集分离的定量检测装置及其检测方法
CN113933129A (zh) * 2021-09-14 2022-01-14 深圳大学 子痫前期诊断试剂盒以及荧光染料的应用
CN113933129B (zh) * 2021-09-14 2024-01-12 深圳大学 子痫前期诊断试剂盒以及荧光染料的应用

Also Published As

Publication number Publication date
US20100261223A1 (en) 2010-10-14
WO2009056340A3 (de) 2009-11-05
JP2011501201A (ja) 2011-01-06
EP2055384A1 (de) 2009-05-06
WO2009056340A2 (de) 2009-05-07
EP2205355A2 (de) 2010-07-14

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Application publication date: 20101110