CN101875957A - 中国仓鼠凋亡相关基因 - Google Patents

中国仓鼠凋亡相关基因 Download PDF

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Publication number
CN101875957A
CN101875957A CN2010102090324A CN201010209032A CN101875957A CN 101875957 A CN101875957 A CN 101875957A CN 2010102090324 A CN2010102090324 A CN 2010102090324A CN 201010209032 A CN201010209032 A CN 201010209032A CN 101875957 A CN101875957 A CN 101875957A
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CN
China
Prior art keywords
sequence
cells
cell
seq
expression
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Pending
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CN2010102090324A
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English (en)
Chinese (zh)
Inventor
黄智宏
米兰达·G·S·亚普
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Agency for Science Technology and Research Singapore
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Agency for Science Technology and Research Singapore
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Publication of CN101875957A publication Critical patent/CN101875957A/zh
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747Apoptosis related proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/57IFN-gamma
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN2010102090324A 2004-12-30 2005-12-28 中国仓鼠凋亡相关基因 Pending CN101875957A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64033304P 2004-12-30 2004-12-30
US60/640,333 2004-12-30

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNA2005800488118A Division CN101133156A (zh) 2004-12-30 2005-12-28 中国仓鼠凋亡相关基因

Publications (1)

Publication Number Publication Date
CN101875957A true CN101875957A (zh) 2010-11-03

Family

ID=36615341

Family Applications (3)

Application Number Title Priority Date Filing Date
CN2010102090324A Pending CN101875957A (zh) 2004-12-30 2005-12-28 中国仓鼠凋亡相关基因
CNA2005800488118A Pending CN101133156A (zh) 2004-12-30 2005-12-28 中国仓鼠凋亡相关基因
CN2010102090432A Pending CN101875692A (zh) 2004-12-30 2005-12-28 中国仓鼠凋亡相关基因

Family Applications After (2)

Application Number Title Priority Date Filing Date
CNA2005800488118A Pending CN101133156A (zh) 2004-12-30 2005-12-28 中国仓鼠凋亡相关基因
CN2010102090432A Pending CN101875692A (zh) 2004-12-30 2005-12-28 中国仓鼠凋亡相关基因

Country Status (9)

Country Link
US (5) US7846894B2 (https=)
EP (6) EP2298890A1 (https=)
JP (1) JP5089400B2 (https=)
KR (1) KR20070082597A (https=)
CN (3) CN101875957A (https=)
AU (1) AU2005322686B2 (https=)
IL (1) IL183361A0 (https=)
SG (1) SG158841A1 (https=)
WO (1) WO2006071200A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107881151A (zh) * 2012-06-14 2018-04-06 赛诺菲 Cho表达系统

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6200437B2 (ja) 2012-03-16 2017-09-20 ユニバーシティ ヘルス ネットワーク Toso活性を調節するための方法および組成物
WO2014068048A1 (en) * 2012-11-05 2014-05-08 Celonic Ag Expression system
JP2016523264A (ja) 2013-07-03 2016-08-08 ユニバーシティ ヘルス ネットワーク Tosoに対する抗体
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
CN107630038A (zh) * 2017-09-15 2018-01-26 浙江大学 提高老年大鼠骨髓间充质干细胞移植后生存能力的方法
WO2019180607A1 (en) * 2018-03-19 2019-09-26 Centre For Cellular And Molecular Platforms A vector, a host cell and a method thereof
CN108359632A (zh) * 2018-03-30 2018-08-03 吉林冠界生物技术有限公司 Mdck细胞系、复制病毒的方法及其应用

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US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
ATE243754T1 (de) 1987-05-21 2003-07-15 Micromet Ag Multifunktionelle proteine mit vorbestimmter zielsetzung
EP0436597B1 (en) 1988-09-02 1997-04-02 Protein Engineering Corporation Generation and selection of recombinant varied binding proteins
EP0368684B2 (en) 1988-11-11 2004-09-29 Medical Research Council Cloning immunoglobulin variable domain sequences.
US5641670A (en) 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
US6747138B1 (en) 1995-04-03 2004-06-08 Regents Of The University Of Michigan Methods and compositions for regulating Fas-associated apoptosis
EP0816497A3 (en) * 1996-06-26 1999-12-22 Smithkline Beecham Corporation Human requiem polypeptide for apoptosis
US6544523B1 (en) 1996-11-13 2003-04-08 Chiron Corporation Mutant forms of Fas ligand and uses thereof
GB9625283D0 (en) * 1996-12-04 1997-01-22 Janssen Pharmaceutica Nv Vertebrate homologues of unc-53 protein of c.elegans or functional eqivalents thereof and cdna sequences coding for said homologue
US20040143111A1 (en) * 1997-04-17 2004-07-22 Incyte Corporation Novel apoptosis-associated protein
US6451759B1 (en) 1998-01-14 2002-09-17 The Regents Of The University Of California Noncleavable Fas ligand
AU3753099A (en) * 1998-04-21 1999-11-08 Trustees Of Boston University Novel genes and methods that modulate apoptosis
US6683168B1 (en) 1998-04-21 2004-01-27 Boston Medical Center Corporation Genes and methods that modulate apoptosis
US6015712A (en) * 1999-07-19 2000-01-18 Isis Pharmaceuticals Inc. Antisense modulation of FADD expression
CA2384880C (en) * 1999-09-27 2010-09-21 Genentech, Inc. Methods for making recombinant proteins using apoptosis inhibitors
US7575860B2 (en) * 2000-03-07 2009-08-18 Evans David H DNA joining method
US20040023385A1 (en) * 2002-08-05 2004-02-05 Isis Pharmaceuticals Inc. Antisense modulation of requiem expression
WO2004070025A2 (en) * 2003-02-05 2004-08-19 Juan Saus Novel goodpasture antigen-binding protein isoforms and protein misfolded-mediated disorders
CN1548054A (zh) * 2003-05-08 2004-11-24 陆爱丽 预防或治疗sars冠状病毒的药物

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107881151A (zh) * 2012-06-14 2018-04-06 赛诺菲 Cho表达系统

Also Published As

Publication number Publication date
US7846894B2 (en) 2010-12-07
JP2008526200A (ja) 2008-07-24
EP2298890A1 (en) 2011-03-23
SG158841A1 (en) 2010-02-26
IL183361A0 (en) 2007-09-20
EP2298889A1 (en) 2011-03-23
US20110318316A1 (en) 2011-12-29
EP2298888A1 (en) 2011-03-23
JP5089400B2 (ja) 2012-12-05
US20110318317A1 (en) 2011-12-29
EP1997890A1 (en) 2008-12-03
US20080295190A1 (en) 2008-11-27
WO2006071200A2 (en) 2006-07-06
WO2006071200A3 (en) 2007-01-25
CN101133156A (zh) 2008-02-27
AU2005322686A1 (en) 2006-07-06
US20110318831A1 (en) 2011-12-29
KR20070082597A (ko) 2007-08-21
US20110129927A1 (en) 2011-06-02
EP2298887A1 (en) 2011-03-23
CN101875692A (zh) 2010-11-03
AU2005322686B2 (en) 2012-01-19
EP1831366A2 (en) 2007-09-12

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