CN101855354B - 合成增加量的葡糖胺聚糖的植物 - Google Patents

合成增加量的葡糖胺聚糖的植物 Download PDF

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Publication number
CN101855354B
CN101855354B CN200880115486.6A CN200880115486A CN101855354B CN 101855354 B CN101855354 B CN 101855354B CN 200880115486 A CN200880115486 A CN 200880115486A CN 101855354 B CN101855354 B CN 101855354B
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CN
China
Prior art keywords
nucleic acid
plant
protein
acid molecule
hyaluronan
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Expired - Fee Related
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CN200880115486.6A
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English (en)
Chinese (zh)
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CN101855354A (zh
Inventor
C·弗罗贝格
B·埃西格曼
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BASF SE
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Bayer Technology Services GmbH
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8245—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified carbohydrate or sugar alcohol metabolism, e.g. starch biosynthesis
    • C12N15/8246—Non-starch polysaccharides, e.g. cellulose, fructans, levans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04—Preserving or maintaining viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/08—Reducing the nucleic acid content

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Nutrition Science (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)
CN200880115486.6A 2007-09-12 2008-09-11 合成增加量的葡糖胺聚糖的植物 Expired - Fee Related CN101855354B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP07116174.9 2007-09-12
EP07116174A EP2036983A1 (de) 2007-09-12 2007-09-12 Pflanzen, die erhöhte Mengen an Glucosaminglycanen synthetisieren
US99357507P 2007-09-13 2007-09-13
US60/993,575 2007-09-13
PCT/EP2008/007837 WO2009033752A1 (en) 2007-09-12 2008-09-11 Plants which synthesize increased amounts of glucosaminglycans

Publications (2)

Publication Number Publication Date
CN101855354A CN101855354A (zh) 2010-10-06
CN101855354B true CN101855354B (zh) 2016-04-06

Family

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Family Applications (1)

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CN200880115486.6A Expired - Fee Related CN101855354B (zh) 2007-09-12 2008-09-11 合成增加量的葡糖胺聚糖的植物

Country Status (9)

Country Link
US (1) US9150873B2 (enExample)
EP (2) EP2036983A1 (enExample)
JP (1) JP5529741B2 (enExample)
CN (1) CN101855354B (enExample)
AR (1) AR068623A1 (enExample)
AT (1) ATE551425T1 (enExample)
AU (1) AU2008297527B2 (enExample)
CA (1) CA2698989C (enExample)
WO (1) WO2009033752A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2947597B2 (ja) 1990-07-27 1999-09-13 日本油脂株式会社 鋳物加工品の塗装方法及びそれによって得られた意匠性鋳物塗装品
JP5081629B2 (ja) * 2005-12-15 2012-11-28 生化学工業株式会社 長鎖コンドロイチン糖鎖及びその製造方法並びにコンドロイチン合成の促進方法
CN106755022B (zh) * 2015-11-25 2020-08-04 中国科学院大连化学物理研究所 乙酰葡萄糖胺磷酸变位酶AtAGM编码基因及其酶、制备、应用与酶活性检测方法
CN113528482B (zh) * 2021-08-02 2024-02-06 山东大学 高活性肝素骨架合酶PmHS2突变体及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN85103471A (zh) * 1985-04-27 1986-10-29 广西化工研究所 植物生长调节剂
CN85100964A (zh) * 1985-04-01 1988-02-17 赵凤源 树木多代嫁接繁殖法

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4141973A (en) * 1975-10-17 1979-02-27 Biotrics, Inc. Ultrapure hyaluronic acid and the use thereof
NL8300698A (nl) 1983-02-24 1984-09-17 Univ Leiden Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten.
NO161573C (no) 1983-11-25 1989-08-30 Miles Inc Fremgangsmaate til fremstilling av hyaluronsyre.
JPS60251898A (ja) * 1984-05-25 1985-12-12 Shiseido Co Ltd 醗酵法によるヒアルロン酸の製造方法
US5565347A (en) * 1986-06-10 1996-10-15 Calgene, Inc. Transformation and foreign gene expression with plant species
NO173355C (no) * 1987-03-03 1993-12-01 Chugai Pharmaceutical Co Ltd Fremgangsm}te og selektiv bestemmelse av en h!ymolekylvekts hyaluronsyre og reagenssett for utf!relse av fremgangsm}ten
ES2074999T3 (es) 1987-05-20 1995-10-01 Ciba Geigy Ag Plantas de zea mays y plantas de zea mays transgenicas regeneradas de protoplastos o celulas derivadas de protoplastos.
US4897349A (en) * 1989-04-28 1990-01-30 Medchem Products, Inc. Biosynthesis of hyaluronic acid
US7705215B1 (en) 1990-04-17 2010-04-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
DK0465875T3 (da) 1990-06-23 1999-08-09 Hoechst Schering Agrevo Gmbh Fremgangsmåde til produktion af en calluskultur af Zea mays (L.)
JPH05199877A (ja) 1991-10-03 1993-08-10 Sumitomo Chem Co Ltd バレイショおよびイネの誘導型植物防御遺伝子の制御領域、その用途およびアッセイ法
US6455304B1 (en) * 1994-07-01 2002-09-24 The Board Of Regents Of The University Of Oklahoma Hyaluronate synthase gene and uses thereof
IT1271001B (it) 1994-07-26 1997-05-26 Poli Ind Chimica Spa Procedimento di preparazione di acido ialuronico mediante fermentazione con streptococcus
DE19619918A1 (de) * 1996-05-17 1997-11-20 Planttec Biotechnologie Gmbh Nucleinsäuremoleküle codierend lösliche Stärkesynthasen aus Mais
GB9702592D0 (en) 1997-02-07 1997-03-26 Danisco Selection method
US6369298B1 (en) * 1997-04-30 2002-04-09 Pioneer Hi-Bred International, Inc. Agrobacterium mediated transformation of sorghum
US20030104601A1 (en) * 1999-04-01 2003-06-05 Deangelis Paul L. Chondroitin synthase gene and methods of making and using same
US7094581B2 (en) * 1998-10-26 2006-08-22 The Board Of Regents Of The University Of Oklahoma Hyaluronan synthases and methods of making and using same
JP2001060708A (ja) * 1999-06-18 2001-03-06 Nippon Sheet Glass Co Ltd 透明積層体およびこれを用いたガラス物品
AR044724A1 (es) 2000-03-27 2005-10-05 Syngenta Participations Ag Promotores del virus de la rizadura amarilla del cestrum
US6607745B2 (en) * 2001-05-18 2003-08-19 Harry Leneau Ingestion of hyaluronic acid for improved joint function and health
JP4702819B2 (ja) * 2001-08-01 2011-06-15 生化学工業株式会社 コンドロイチン合成酵素
JP4101548B2 (ja) * 2001-08-10 2008-06-18 生化学工業株式会社 コンドロイチン合成酵素及びそれをコードするｄｎａ
US7811806B2 (en) * 2001-12-21 2010-10-12 Novozymes, Inc. Methods for producing hyaluronan in a recombinant host cell
US20040003432A1 (en) * 2002-05-06 2004-01-01 Pharmacia Corporation Production of hexosamines and uses thereof
DE60324797D1 (de) * 2002-05-31 2009-01-02 Seikagaku Kogyo Co Ltd Chondroitinsynthetase und das enzym codierende dna
ES2354696T3 (es) * 2003-07-31 2011-03-17 Toyo Boseki Kabushiki Kaisha Planta que produce ácido hialurónico.
PT1805312E (pt) * 2004-09-23 2009-09-28 Bayer Cropscience Ag Processos e meios para produzir hialurano
EP1640457A1 (de) * 2004-09-23 2006-03-29 Bayer CropScience GmbH Verfahren und Mittel zur Herstellung von Hyaluronan
BRPI0614885A2 (pt) * 2005-08-25 2011-04-19 Toyo Boseki planta produtora de ácido hialurÈnico
JP2009509555A (ja) * 2005-10-05 2009-03-12 バイエル・クロップサイエンス・アーゲー ヒアルロン酸の産生が増大した植物ｉｉ
CA2624496A1 (en) * 2005-10-05 2007-04-12 Bayer Cropscience Ag Plants with an increased production of hyaluronan ii
US8106256B2 (en) * 2005-10-05 2012-01-31 Bayer Cropscience Ag Methods and means for producing hyaluronan
AU2006298964B2 (en) * 2005-10-05 2013-05-02 Bayer Intellectual Property Gmbh Plants having an increased content of amino sugars

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN85100964A (zh) * 1985-04-01 1988-02-17 赵凤源 树木多代嫁接繁殖法
CN85103471A (zh) * 1985-04-27 1986-10-29 广西化工研究所 植物生长调节剂

Also Published As

Publication number Publication date
JP2010538626A (ja) 2010-12-16
AU2008297527B2 (en) 2014-07-17
CA2698989A1 (en) 2009-03-19
ATE551425T1 (de) 2012-04-15
EP2190998B1 (en) 2012-03-28
US9150873B2 (en) 2015-10-06
JP5529741B2 (ja) 2014-06-25
CN101855354A (zh) 2010-10-06
AU2008297527A1 (en) 2009-03-19
EP2036983A1 (de) 2009-03-18
WO2009033752A1 (en) 2009-03-19
US20100196966A1 (en) 2010-08-05
AR068623A1 (es) 2009-11-25
CA2698989C (en) 2018-07-24
EP2190998A1 (en) 2010-06-02

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GR01 Patent grant
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Effective date of registration: 20200323

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Patentee after: BASF SE

Address before: German Monheim

Patentee before: BAYER CROPSCIENCE AG

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CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20160406

Termination date: 20210911