CN101848908B - 激酶抑制剂的组合物及其在治疗癌症和其它与激酶相关的疾病中的用途 - Google Patents

激酶抑制剂的组合物及其在治疗癌症和其它与激酶相关的疾病中的用途 Download PDF

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CN101848908B
CN101848908B CN200880114705.9A CN200880114705A CN101848908B CN 101848908 B CN101848908 B CN 101848908B CN 200880114705 A CN200880114705 A CN 200880114705A CN 101848908 B CN101848908 B CN 101848908B
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heterocycle
alkyl
aryl
cycloalkyl
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CN101848908A (zh
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李嘉强
刘继峰
李有志
李伟
H·罗格夫
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1Globe Biomedical Co Ltd
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Boston Biomedical Inc
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CN200880114705.9A 2007-09-06 2008-09-05 激酶抑制剂的组合物及其在治疗癌症和其它与激酶相关的疾病中的用途 Active CN101848908B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US97041007P 2007-09-06 2007-09-06
US60/970,410 2007-09-06
US1338907P 2007-12-13 2007-12-13
US61/013,389 2007-12-13
US7429508P 2008-06-20 2008-06-20
US61/074,295 2008-06-20
PCT/US2008/075418 WO2009033033A2 (en) 2007-09-06 2008-09-05 Compositions of kinase inhibitors and their use for treatment of cancer and other diseases related to kinases

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CN101848908A CN101848908A (zh) 2010-09-29
CN101848908B true CN101848908B (zh) 2014-07-02

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US (5) US8299106B2 (https=)
EP (2) EP3037419B1 (https=)
JP (5) JP5452490B2 (https=)
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CA (1) CA2736177A1 (https=)
CY (1) CY1118012T1 (https=)
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EP3037419B1 (en) * 2007-09-06 2019-09-04 Boston Biomedical, Inc. Compositions of kinase inhibitors and their use for treatment of cancer and other diseases related to kinases
KR101300916B1 (ko) * 2007-12-10 2013-08-27 인터디지탈 패튼 홀딩스, 인크 무선 링크 제어 패킷 폐기 및 무선 링크 제어 재확립을 트리거하는 방법 및 장치
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HK1220184A1 (zh) * 2013-03-13 2017-04-28 Boston Biomedical, Inc. 用於治疗癌症的作为癌症干细胞途径激酶抑制剂的3-(芳基或杂芳基)甲基吲哚-2-酮衍生物
WO2014202528A1 (en) * 2013-06-20 2014-12-24 Boehringer Ingelheim International Gmbh Olefin substituted oxindoles having ampk activity
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CN107683137A (zh) * 2015-04-27 2018-02-09 波士顿生物医药有限公司 用于使用stat3途径抑制剂和激酶抑制剂治疗癌症的方法
US10377749B2 (en) 2015-08-10 2019-08-13 Sumitomo Dainippon Pharma Co., Ltd. Purification method for 5-(thiazol-4-yl)indolin-2-one derivative
WO2017160978A1 (en) 2016-03-15 2017-09-21 Boston Biomedical, Inc. Cell cultures and use thereof
JP2019519573A (ja) 2016-06-28 2019-07-11 ボストン バイオメディカル， インコーポレイテッド がんを処置するための方法
WO2018098352A2 (en) 2016-11-22 2018-05-31 Jun Oishi Targeting kras induced immune checkpoint expression
JP7106563B2 (ja) 2016-11-29 2022-07-26 スミトモ ファーマ オンコロジー， インコーポレイテッド ナフトフラン誘導体、その調製、および使用方法
CN117224541A (zh) * 2018-09-18 2023-12-15 北京强新生物科技有限公司 肥胖症的治疗
MX2021003156A (es) * 2018-09-18 2021-05-14 1 Globe Biomedical Co Ltd Tratamiento para la enfermedad del higado graso no alcoholico.
CA3237696A1 (en) 2021-11-08 2023-05-11 Progentos Therapeutics, Inc. Platelet-derived growth factor receptor (pdgfr) alpha inhibitors and uses thereof

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EP3037419A1 (en) 2016-06-29
JP5974124B2 (ja) 2016-08-23
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EP2197878A4 (en) 2012-02-08
ES2759347T3 (es) 2020-05-08
EP2197878A2 (en) 2010-06-23
JP2016180013A (ja) 2016-10-13
SI2197878T1 (sl) 2016-10-28
CY1118012T1 (el) 2017-05-17
LT2197878T (lt) 2016-09-26
JP2014058573A (ja) 2014-04-03
WO2009033033A3 (en) 2009-04-30
US9725444B2 (en) 2017-08-08
EP2197878B1 (en) 2016-08-17
JP2019070051A (ja) 2019-05-09
US8299106B2 (en) 2012-10-30
JP5452490B2 (ja) 2014-03-26
WO2009033033A2 (en) 2009-03-12
JP6495868B2 (ja) 2019-04-03
EP3037419B1 (en) 2019-09-04
PL2197878T3 (pl) 2017-01-31
JP2010538091A (ja) 2010-12-09
CN101848908A (zh) 2010-09-29
US20190248781A1 (en) 2019-08-15
HRP20161114T1 (hr) 2016-11-04
DK2197878T3 (en) 2016-11-14
HK1226071A1 (en) 2017-09-22
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JP5701372B2 (ja) 2015-04-15
US20100285006A1 (en) 2010-11-11
US20150197517A1 (en) 2015-07-16
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