CN101821612A - 用于液相色谱洗脱液的转向的系统和方法 - Google Patents

用于液相色谱洗脱液的转向的系统和方法 Download PDF

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Publication number
CN101821612A
CN101821612A CN200880104228A CN200880104228A CN101821612A CN 101821612 A CN101821612 A CN 101821612A CN 200880104228 A CN200880104228 A CN 200880104228A CN 200880104228 A CN200880104228 A CN 200880104228A CN 101821612 A CN101821612 A CN 101821612A
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CN
China
Prior art keywords
flow
port
waste
mass spectrometer
injection valve
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Pending
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CN200880104228A
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English (en)
Chinese (zh)
Inventor
江同保
切瑞尔·佛罗
莫瑞斯·G·菲伦
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EMD Millipore Corp
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Millipore Corp
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Publication of CN101821612A publication Critical patent/CN101821612A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/84—Preparation of the fraction to be distributed

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
CN200880104228A 2007-08-24 2008-08-22 用于液相色谱洗脱液的转向的系统和方法 Pending CN101821612A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96611607P 2007-08-24 2007-08-24
US60/966,116 2007-08-24
PCT/US2008/010027 WO2009029232A1 (en) 2007-08-24 2008-08-22 System and method for diversion of a liquid chromatography eluant

Publications (1)

Publication Number Publication Date
CN101821612A true CN101821612A (zh) 2010-09-01

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ID=40029004

Family Applications (1)

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CN200880104228A Pending CN101821612A (zh) 2007-08-24 2008-08-22 用于液相色谱洗脱液的转向的系统和方法

Country Status (7)

Country Link
US (1) US8436297B2 (enExample)
EP (2) EP2181325A1 (enExample)
JP (1) JP2010537197A (enExample)
CN (1) CN101821612A (enExample)
ES (1) ES2436744T3 (enExample)
SG (1) SG183001A1 (enExample)
WO (1) WO2009029232A1 (enExample)

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JP5188389B2 (ja) 2005-05-05 2013-04-24 ボストン サイエンティフィック リミテッド 肺静脈口を画像として再構築する予成形した位置確認カテーテル及びシステム
WO2009029231A2 (en) 2007-08-24 2009-03-05 Millipore Corporation Method of detecting filter extractables in biopharmaceutical products by liquid chromatography-mass spectrometry
US8436297B2 (en) * 2007-08-24 2013-05-07 Emd Millipore Corporation System and method for diversion of a liquid chromatography eluant
CN103293253B (zh) * 2013-05-24 2015-04-01 中国科学院过程工程研究所 生物技术药物高效纯化分析系统及其药物分离检测方法
JP6918555B2 (ja) * 2016-04-13 2021-08-11 株式会社堀場エステック クロマトグラフ用サンプラ及びクロマトグラフ用サンプラの操作方法
RU2653570C1 (ru) * 2017-07-14 2018-05-11 Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр питания, биотехнологии и безопасности пищи Способ количественного определения органических кислот (уксусной, яблочной, молочной) и углеводов (мальтозы, глюкозы, фруктозы) в полупродуктах спиртового производства методом высокоэффективной жидкостной хроматографии
CN109270192B (zh) * 2018-12-02 2024-02-02 太湖流域水文水资源监测中心（太湖流域水环境监测中心） 用于水产品磺胺类抗生素检测的前处理装置、方法和用途
EP3922989B1 (en) * 2019-02-04 2024-11-20 Hitachi High-Tech Corporation Liquid chromatograph mass spectrometer
GB202219580D0 (en) * 2022-12-22 2023-02-08 Thermo Fisher Scient Bremen Gmbh System and method for delivery of an analyte and a reference

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US20050194318A1 (en) * 2001-04-25 2005-09-08 Can Ozbal High throughput autosampler
US20070048187A1 (en) * 2002-10-30 2007-03-01 Sheehan Terry L Use of temperature and flow profiles in gradient elution based analytical process
CN1936572A (zh) * 2005-09-23 2007-03-28 中国科学院大连化学物理研究所 一种超临界流体萃取－高效液相色谱联用系统

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5703360A (en) * 1996-08-30 1997-12-30 Hewlett-Packard Company Automated calibrant system for use in a liquid separation/mass spectrometry apparatus
US20050194318A1 (en) * 2001-04-25 2005-09-08 Can Ozbal High throughput autosampler
US20070048187A1 (en) * 2002-10-30 2007-03-01 Sheehan Terry L Use of temperature and flow profiles in gradient elution based analytical process
CN1936572A (zh) * 2005-09-23 2007-03-28 中国科学院大连化学物理研究所 一种超临界流体萃取－高效液相色谱联用系统

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LI SUN ET AL.: "The effect of β-cyclodextrin on liquid chromatography/electrospray-mass spectrometry analysis of hydrophobic drug molecules", 《JOURNAL OF CHROMATOGRAPHY A》 *

Also Published As

Publication number Publication date
US8436297B2 (en) 2013-05-07
US20110114833A1 (en) 2011-05-19
JP2010537197A (ja) 2010-12-02
EP2508880B1 (en) 2013-11-13
ES2436744T3 (es) 2014-01-07
SG183001A1 (en) 2012-08-30
EP2508880A1 (en) 2012-10-10
WO2009029232A1 (en) 2009-03-05
EP2181325A1 (en) 2010-05-05

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