JP2010537197A - 液体クロマトグラフィー溶離液を排流するためのシステム及び方法 - Google Patents
液体クロマトグラフィー溶離液を排流するためのシステム及び方法 Download PDFInfo
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- LJCNRYVRMXRIQR-OLXYHTOASA-L potassium sodium L-tartrate Chemical compound [Na+].[K+].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O LJCNRYVRMXRIQR-OLXYHTOASA-L 0.000 description 1
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- MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 description 1
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- LROWVYNUWKVTCU-STWYSWDKSA-M sodium sorbate Chemical compound [Na+].C\C=C\C=C\C([O-])=O LROWVYNUWKVTCU-STWYSWDKSA-M 0.000 description 1
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- AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 1
- 235000019345 sodium thiosulphate Nutrition 0.000 description 1
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- PPASLZSBLFJQEF-RXSVEWSESA-M sodium-L-ascorbate Chemical compound [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RXSVEWSESA-M 0.000 description 1
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- 239000005720 sucrose Substances 0.000 description 1
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- GFYHSKONPJXCDE-UHFFFAOYSA-N sym-collidine Natural products CC1=CN=C(C)C(C)=C1 GFYHSKONPJXCDE-UHFFFAOYSA-N 0.000 description 1
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- NEUOBESLMIKJSB-UHFFFAOYSA-J tetrasodium;tetraacetate Chemical compound [Na+].[Na+].[Na+].[Na+].CC([O-])=O.CC([O-])=O.CC([O-])=O.CC([O-])=O NEUOBESLMIKJSB-UHFFFAOYSA-J 0.000 description 1
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- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 description 1
- 235000013337 tricalcium citrate Nutrition 0.000 description 1
- KRSIWAJXDVVKLZ-UHFFFAOYSA-H tricalcium;2,4,6,8,10,12-hexaoxido-1,3,5,7,9,11-hexaoxa-2$l^{5},4$l^{5},6$l^{5},8$l^{5},10$l^{5},12$l^{5}-hexaphosphacyclododecane 2,4,6,8,10,12-hexaoxide Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P1(=O)OP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OP([O-])(=O)O1 KRSIWAJXDVVKLZ-UHFFFAOYSA-H 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
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- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
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- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/72—Mass spectrometers
- G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/84—Preparation of the fraction to be distributed
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Applications Claiming Priority (2)
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| US96611607P | 2007-08-24 | 2007-08-24 | |
| PCT/US2008/010027 WO2009029232A1 (en) | 2007-08-24 | 2008-08-22 | System and method for diversion of a liquid chromatography eluant |
Publications (2)
| Publication Number | Publication Date |
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| JP2010537197A true JP2010537197A (ja) | 2010-12-02 |
| JP2010537197A5 JP2010537197A5 (enExample) | 2012-03-01 |
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| US (1) | US8436297B2 (enExample) |
| EP (2) | EP2181325A1 (enExample) |
| JP (1) | JP2010537197A (enExample) |
| CN (1) | CN101821612A (enExample) |
| ES (1) | ES2436744T3 (enExample) |
| SG (1) | SG183001A1 (enExample) |
| WO (1) | WO2009029232A1 (enExample) |
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| JP5188389B2 (ja) | 2005-05-05 | 2013-04-24 | ボストン サイエンティフィック リミテッド | 肺静脈口を画像として再構築する予成形した位置確認カテーテル及びシステム |
| WO2009029231A2 (en) | 2007-08-24 | 2009-03-05 | Millipore Corporation | Method of detecting filter extractables in biopharmaceutical products by liquid chromatography-mass spectrometry |
| US8436297B2 (en) * | 2007-08-24 | 2013-05-07 | Emd Millipore Corporation | System and method for diversion of a liquid chromatography eluant |
| CN103293253B (zh) * | 2013-05-24 | 2015-04-01 | 中国科学院过程工程研究所 | 生物技术药物高效纯化分析系统及其药物分离检测方法 |
| JP6918555B2 (ja) * | 2016-04-13 | 2021-08-11 | 株式会社堀場エステック | クロマトグラフ用サンプラ及びクロマトグラフ用サンプラの操作方法 |
| RU2653570C1 (ru) * | 2017-07-14 | 2018-05-11 | Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр питания, биотехнологии и безопасности пищи | Способ количественного определения органических кислот (уксусной, яблочной, молочной) и углеводов (мальтозы, глюкозы, фруктозы) в полупродуктах спиртового производства методом высокоэффективной жидкостной хроматографии |
| CN109270192B (zh) * | 2018-12-02 | 2024-02-02 | 太湖流域水文水资源监测中心（太湖流域水环境监测中心） | 用于水产品磺胺类抗生素检测的前处理装置、方法和用途 |
| EP3922989B1 (en) * | 2019-02-04 | 2024-11-20 | Hitachi High-Tech Corporation | Liquid chromatograph mass spectrometer |
| GB202219580D0 (en) * | 2022-12-22 | 2023-02-08 | Thermo Fisher Scient Bremen Gmbh | System and method for delivery of an analyte and a reference |
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| US5703360A (en) * | 1996-08-30 | 1997-12-30 | Hewlett-Packard Company | Automated calibrant system for use in a liquid separation/mass spectrometry apparatus |
| JP2004510979A (ja) * | 2000-10-03 | 2004-04-08 | ダイオネックス コーポレイション | 液体クロマトグラフィ−質量分析計（ｌｃ−ｍｓ）分析におけるピークパーキングのための方法及びシステム |
| JP2005069817A (ja) * | 2003-08-22 | 2005-03-17 | Shimadzu Corp | 液体クロマトグラフ質量分析装置 |
| JP2006504972A (ja) * | 2002-10-30 | 2006-02-09 | バリアン・インコーポレイテッド | 傾斜溶離に基づく分析プロセスにおける温度および流量プロフィールの使用法 |
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| US4962042A (en) * | 1988-05-25 | 1990-10-09 | The Dow Chemical Company | Method for on-column injection gas chromatography |
| US4891137A (en) * | 1989-03-03 | 1990-01-02 | Spectra-Physics, Inc. | Method and apparatus for membrane extraction of hydrolysis contaminates |
| US5693620A (en) * | 1991-07-31 | 1997-12-02 | Oncomembrane, Inc. | Plasmalopsychosines and plasmalocerebrosides |
| US5468643A (en) * | 1991-08-28 | 1995-11-21 | The United States Of America As Represented By The Department Of Health And Human Services | Switching valve system for direct biological sample injection for LC analysis |
| US6213122B1 (en) | 1997-10-01 | 2001-04-10 | 3M Innovative Properties Company | Electret fibers and filter webs having a low level of extractable hydrocarbons |
| AU2986400A (en) * | 1999-02-08 | 2000-08-25 | Admetric Biochem Inc. | Chromatographic system with pre-detector eluent switching |
| US7588725B2 (en) * | 2001-04-25 | 2009-09-15 | Biotrove, Inc. | High throughput autosampler |
| US8414774B2 (en) * | 2001-04-25 | 2013-04-09 | Agilent Technologies, Inc. | Systems and methods for high-throughput screening of fluidic samples |
| US7220383B2 (en) | 2001-07-13 | 2007-05-22 | Metara, Inc. | Method and instrument for automated analysis of fluid-based processing systems |
| US7132080B2 (en) * | 2003-08-15 | 2006-11-07 | Metara, Inc. | Module for automated matrix removal |
| KR101276987B1 (ko) * | 2005-01-25 | 2013-06-25 | 바이엘 크롭사이언스 아게 | 아인산, 포세틸-ａｌ 또는 두 가지 모두의 동시적 분석방법 |
| US8047060B2 (en) * | 2005-01-31 | 2011-11-01 | Waters Technologies Corporation | Method and apparatus for sample injection in liquid chromatography |
| CN1936572A (zh) * | 2005-09-23 | 2007-03-28 | 中国科学院大连化学物理研究所 | 一种超临界流体萃取－高效液相色谱联用系统 |
| FR2896585B1 (fr) * | 2006-01-20 | 2008-12-05 | Commissariat Energie Atomique | Introduction d'additifs pour une interface d'ionisation a pression atmospherique en entree d'un spectrometre |
| JP4913470B2 (ja) * | 2006-04-26 | 2012-04-11 | 株式会社島津製作所 | 流路切換えバルブを用いた高速液体クロマトグラフ及び分析方法 |
| US8642351B2 (en) * | 2006-09-20 | 2014-02-04 | Waters Technologies Corporation | Apparatus and methods of fluid chromatography |
| WO2008079914A1 (en) * | 2006-12-21 | 2008-07-03 | Novartis Ag | Antibody quantitation |
| US8436297B2 (en) * | 2007-08-24 | 2013-05-07 | Emd Millipore Corporation | System and method for diversion of a liquid chromatography eluant |
| WO2009029231A2 (en) | 2007-08-24 | 2009-03-05 | Millipore Corporation | Method of detecting filter extractables in biopharmaceutical products by liquid chromatography-mass spectrometry |
| US8106351B2 (en) * | 2008-08-08 | 2012-01-31 | Quest Diagnostics Investments Incorporated | Mass spectrometry assay for plasma-renin |
| US7834313B2 (en) * | 2008-08-08 | 2010-11-16 | Quest Diagnostics Investments Incorporated | Mass spectrometry assay for plasma-renin |
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2008
- 2008-08-22 US US12/674,870 patent/US8436297B2/en not_active Expired - Fee Related
- 2008-08-22 ES ES12175163.0T patent/ES2436744T3/es active Active
- 2008-08-22 EP EP08828269A patent/EP2181325A1/en not_active Withdrawn
- 2008-08-22 WO PCT/US2008/010027 patent/WO2009029232A1/en not_active Ceased
- 2008-08-22 SG SG2012049920A patent/SG183001A1/en unknown
- 2008-08-22 JP JP2010521894A patent/JP2010537197A/ja active Pending
- 2008-08-22 EP EP12175163.0A patent/EP2508880B1/en not_active Not-in-force
- 2008-08-22 CN CN200880104228A patent/CN101821612A/zh active Pending
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| US5703360A (en) * | 1996-08-30 | 1997-12-30 | Hewlett-Packard Company | Automated calibrant system for use in a liquid separation/mass spectrometry apparatus |
| JP2004510979A (ja) * | 2000-10-03 | 2004-04-08 | ダイオネックス コーポレイション | 液体クロマトグラフィ−質量分析計（ｌｃ−ｍｓ）分析におけるピークパーキングのための方法及びシステム |
| JP2006504972A (ja) * | 2002-10-30 | 2006-02-09 | バリアン・インコーポレイテッド | 傾斜溶離に基づく分析プロセスにおける温度および流量プロフィールの使用法 |
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Also Published As
| Publication number | Publication date |
|---|---|
| US8436297B2 (en) | 2013-05-07 |
| US20110114833A1 (en) | 2011-05-19 |
| CN101821612A (zh) | 2010-09-01 |
| EP2508880B1 (en) | 2013-11-13 |
| ES2436744T3 (es) | 2014-01-07 |
| SG183001A1 (en) | 2012-08-30 |
| EP2508880A1 (en) | 2012-10-10 |
| WO2009029232A1 (en) | 2009-03-05 |
| EP2181325A1 (en) | 2010-05-05 |
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