ES2436744T3 - Sistema para derivar un eluyente de cromatografía de líquidos - Google Patents

Sistema para derivar un eluyente de cromatografía de líquidos Download PDF

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Publication number
ES2436744T3
ES2436744T3 ES12175163.0T ES12175163T ES2436744T3 ES 2436744 T3 ES2436744 T3 ES 2436744T3 ES 12175163 T ES12175163 T ES 12175163T ES 2436744 T3 ES2436744 T3 ES 2436744T3
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ES
Spain
Prior art keywords
flow
port
waste
mass spectrometer
liquid chromatography
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES12175163.0T
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English (en)
Spanish (es)
Inventor
Tongbo Jiang
Cheryl Follo
Maurice G. Phelan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EMD Millipore Corp
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EMD Millipore Corp
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Application filed by EMD Millipore Corp filed Critical EMD Millipore Corp
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Publication of ES2436744T3 publication Critical patent/ES2436744T3/es
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/84—Preparation of the fraction to be distributed

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
ES12175163.0T 2007-08-24 2008-08-22 Sistema para derivar un eluyente de cromatografía de líquidos Active ES2436744T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96611607P 2007-08-24 2007-08-24
US966116P 2007-08-24

Publications (1)

Publication Number Publication Date
ES2436744T3 true ES2436744T3 (es) 2014-01-07

Family

ID=40029004

Family Applications (1)

Application Number Title Priority Date Filing Date
ES12175163.0T Active ES2436744T3 (es) 2007-08-24 2008-08-22 Sistema para derivar un eluyente de cromatografía de líquidos

Country Status (7)

Country Link
US (1) US8436297B2 (enExample)
EP (2) EP2508880B1 (enExample)
JP (1) JP2010537197A (enExample)
CN (1) CN101821612A (enExample)
ES (1) ES2436744T3 (enExample)
SG (1) SG183001A1 (enExample)
WO (1) WO2009029232A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1876985B1 (en) 2005-05-05 2016-08-31 Boston Scientific Scimed, Inc. System for graphically reconstructing pulmonary vein ostia with preshaped localization catheter
SG183001A1 (en) * 2007-08-24 2012-08-30 Emd Millipore Corp System and method for diversion of a liquid chromatography eluant
CN101815939A (zh) 2007-08-24 2010-08-25 密理博公司 以液相色谱质谱法检测生物药剂产品中的过滤器可提取物的方法
CN103293253B (zh) * 2013-05-24 2015-04-01 中国科学院过程工程研究所 生物技术药物高效纯化分析系统及其药物分离检测方法
JP6918555B2 (ja) * 2016-04-13 2021-08-11 株式会社堀場エステック クロマトグラフ用サンプラ及びクロマトグラフ用サンプラの操作方法
RU2653570C1 (ru) * 2017-07-14 2018-05-11 Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр питания, биотехнологии и безопасности пищи Способ количественного определения органических кислот (уксусной, яблочной, молочной) и углеводов (мальтозы, глюкозы, фруктозы) в полупродуктах спиртового производства методом высокоэффективной жидкостной хроматографии
CN109270192B (zh) * 2018-12-02 2024-02-02 太湖流域水文水资源监测中心（太湖流域水环境监测中心） 用于水产品磺胺类抗生素检测的前处理装置、方法和用途
CN113383232B (zh) * 2019-02-04 2023-09-19 株式会社日立高新技术 液相色谱质量分析装置
GB202219580D0 (en) * 2022-12-22 2023-02-08 Thermo Fisher Scient Bremen Gmbh System and method for delivery of an analyte and a reference

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4962042A (en) * 1988-05-25 1990-10-09 The Dow Chemical Company Method for on-column injection gas chromatography
US4891137A (en) * 1989-03-03 1990-01-02 Spectra-Physics, Inc. Method and apparatus for membrane extraction of hydrolysis contaminates
US5693620A (en) * 1991-07-31 1997-12-02 Oncomembrane, Inc. Plasmalopsychosines and plasmalocerebrosides
US5468643A (en) * 1991-08-28 1995-11-21 The United States Of America As Represented By The Department Of Health And Human Services Switching valve system for direct biological sample injection for LC analysis
US5703360A (en) * 1996-08-30 1997-12-30 Hewlett-Packard Company Automated calibrant system for use in a liquid separation/mass spectrometry apparatus
US6213122B1 (en) 1997-10-01 2001-04-10 3M Innovative Properties Company Electret fibers and filter webs having a low level of extractable hydrocarbons
AU2986400A (en) * 1999-02-08 2000-08-25 Admetric Biochem Inc. Chromatographic system with pre-detector eluent switching
HK1054587A1 (zh) * 2000-10-03 2003-12-05 戴安公司 液相色谱-质谱分析仪(lc-ms)分析中的驻峰方法和系统
US7588725B2 (en) * 2001-04-25 2009-09-15 Biotrove, Inc. High throughput autosampler
US8414774B2 (en) * 2001-04-25 2013-04-09 Agilent Technologies, Inc. Systems and methods for high-throughput screening of fluidic samples
US7220383B2 (en) * 2001-07-13 2007-05-22 Metara, Inc. Method and instrument for automated analysis of fluid-based processing systems
DE60328511D1 (de) * 2002-10-30 2009-09-03 Varian Inc Verwendung von temperatur- und strömungsprofilen bei analytischen prozessen auf gradientenelutionsbasis
US7132080B2 (en) * 2003-08-15 2006-11-07 Metara, Inc. Module for automated matrix removal
JP4258318B2 (ja) * 2003-08-22 2009-04-30 株式会社島津製作所 液体クロマトグラフ質量分析装置
JP5028275B2 (ja) * 2005-01-25 2012-09-19 バイエル・クロップサイエンス・アーゲー 亜リン酸、ホセチル−Ａｌ又は両者を同時に分析する方法
WO2006083776A2 (en) * 2005-01-31 2006-08-10 Waters Investments Limited Method and apparatus for sample injection in liquid chromatography
CN1936572A (zh) * 2005-09-23 2007-03-28 中国科学院大连化学物理研究所 一种超临界流体萃取－高效液相色谱联用系统
FR2896585B1 (fr) * 2006-01-20 2008-12-05 Commissariat Energie Atomique Introduction d'additifs pour une interface d'ionisation a pression atmospherique en entree d'un spectrometre
JP4913470B2 (ja) * 2006-04-26 2012-04-11 株式会社島津製作所 流路切換えバルブを用いた高速液体クロマトグラフ及び分析方法
US8642351B2 (en) * 2006-09-20 2014-02-04 Waters Technologies Corporation Apparatus and methods of fluid chromatography
JP2010515020A (ja) * 2006-12-21 2010-05-06 ノバルティス アーゲー 抗体定量法
SG183001A1 (en) * 2007-08-24 2012-08-30 Emd Millipore Corp System and method for diversion of a liquid chromatography eluant
CN101815939A (zh) * 2007-08-24 2010-08-25 密理博公司 以液相色谱质谱法检测生物药剂产品中的过滤器可提取物的方法
US7834313B2 (en) * 2008-08-08 2010-11-16 Quest Diagnostics Investments Incorporated Mass spectrometry assay for plasma-renin
US8106351B2 (en) * 2008-08-08 2012-01-31 Quest Diagnostics Investments Incorporated Mass spectrometry assay for plasma-renin

Also Published As

Publication number Publication date
JP2010537197A (ja) 2010-12-02
SG183001A1 (en) 2012-08-30
CN101821612A (zh) 2010-09-01
EP2508880B1 (en) 2013-11-13
US8436297B2 (en) 2013-05-07
WO2009029232A1 (en) 2009-03-05
EP2508880A1 (en) 2012-10-10
US20110114833A1 (en) 2011-05-19
EP2181325A1 (en) 2010-05-05

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