CN101797347A - Traditional Chinese medicinal composition for treating gastrointestinal tract and preparation thereof - Google Patents

Traditional Chinese medicinal composition for treating gastrointestinal tract and preparation thereof Download PDF

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CN101797347A
CN101797347A CN 201010143013 CN201010143013A CN101797347A CN 101797347 A CN101797347 A CN 101797347A CN 201010143013 CN201010143013 CN 201010143013 CN 201010143013 A CN201010143013 A CN 201010143013A CN 101797347 A CN101797347 A CN 101797347A
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parts
medicinal composition
rhizoma
rhizoma atractylodis
fructus
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CN101797347B (en
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王志海
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Abstract

The invention relates to a traditional Chinese medicinal composition for treating gastrointestinal tract, in particular to a medicinal composition for treating gastrointestinal tract diseases such as acute and chronic gastritis, enteritis, gastric ulcer, superficial gastritis, gastric acid, gastrectasia, indigestion and the like. The invention also relates to a preparation of the medicinal composition. The traditional Chinese medicinal composition for treating gastrointestinal tract comprises the medicaments in percentage by weight: 10-25 parts of red ginseng, 10-23 parts of poria, 8-20 parts of bighead atractylodes rhizome, 10-25 parts of rhizoma ligustici wallichii, 10-25 parts of rhizoma atractylodis, 10-25 parts of cyperus rotundus, 10-25 parts of medicated leaven, 10-25 parts of gardenia, 10-23 parts of betelnut, 8-20 parts of radix aucklandiae, 5-15 parts of liquorice, 5-8 parts of malt and 10-25 parts of hawthorn. The medicinal composition for treating the gastrointestinal tract is orally taken and has the efficacies of regulating the flow of qi, comforting the stomach, diminishing inflammation, killing pain, repairing gastrointestinal mucosa and ulceration, enhancing gastrointestinal motility, adjusting gastric acid secretion, promoting digestive absorption and the like.

Description

A kind of treatment gastrointestinal Chinese medicine composition and preparation thereof
Technical field
The present invention relates to a kind of pharmaceutical composition, be particularly related to a kind of pharmaceutical composition that is used for the treatment of gastroenteropathys such as acute or chronic gastritis, enteritis, gastric ulcer, superficial gastritis, gastric acid flatulence, dyspepsia, the invention still further relates to the preparation of this pharmaceutical composition.
Background technology
Gastrointestinal disease comprises that acute or chronic gastritis, enteritis, gastric ulcer, superficial gastritis, gastric acid flatulence, dyspepsia, inappetence etc. are commonly encountered diseases, frequently-occurring disease, men and women, old and young no matter, body constitution quality no matter all may be because various former thereby cause the disease of the intestines and stomach aspect.The medicine of treatment gastroenteropathy is a lot, and curative effect is real ideal but seldom, and more medicine can only be alleviated temporarily, cures the symptoms, not the disease.
Summary of the invention
Purpose of the present invention is intended to overcome the defective of prior art, but the Chinese medicine composition of a kind for the treatment of both the principal and secondary aspects of a disease and eutherapeutic treatment gastrointestinal disease is provided.Another object of the present invention provides the preparation of the Chinese medicine composition of this treatment gastrointestinal disease.
The Chinese medicine composition of treatment gastroenteropathy of the present invention is made of the medicine of following weight proportion: Radix Ginseng Rubra 10-25 part, Poria 10-23 part, Rhizoma Atractylodis Macrocephalae 8-20 part, Rhizoma Chuanxiong 10-25 part, Rhizoma Atractylodis 10-25 part, Rhizoma Cyperi 10-25 part, Massa Medicata Fermentata 10-25 part, Fructus Gardeniae 10-25 part, Semen Arecae 10-23 part, Radix Aucklandiae 8-20 part, Radix Glycyrrhizae 5-15 part, Fructus Hordei Germinatus 5-8 part, Fructus Crataegi 10-25 part.
Treatment gastrointestinal Chinese medicine composition of the present invention can be prepared into different dosage forms such as powder, capsule and oral liquid.
Described treatment gastrointestinal Chinese medicine composition composition powders mixes above-mentioned 13 flavor Chinese medicines by weight ratio totally, and technology is ground into the powder packing and makes routinely.
The agent of described treatment gastrointestinal Chinese medicinal composition capsules is above-mentioned 13 flavor Chinese medicines to be mixed by weight ratio technology process decoction lixiviate-purification routinely-concentrate-precipitation-drying-incapsulate shell to make.
Described treatment gastrointestinal Chinese medicine composition oral liquid formulations is that above-mentioned 13 flavor Chinese medicines are mixed by weight ratio, and technology makes through decocting lixiviate-purification-concentrated-packing-sterilization-storage routinely.
Treatment gastrointestinal Chinese medicine composition of the present invention, for oral administration, have and regulate the flow of vital energy, pleasant, antiinflammatory, analgesia, reparation gastrointestinal mucosa and ulcer, enhancing digestive tract power, regulate effects such as gastric acid secretion, digestion promoting absorption.But cure gastroenteropathys such as acute or chronic gastritis, enteritis, gastric ulcer, superficial gastritis, gastric acid flatulence, dyspepsia within a short period of time.This powdered medicine is taken 5 grams at every turn, and capsule is taken 2 at every turn, and oral liquid is taken 10 milliliters at every turn, day obeys three times, is a course of treatment with ten days generally, and patients with mild is cured for one course of treatment, moderate patient cures for two courses of treatment, and severe patient cures for three courses of treatment, no longer recurrence for many years after healing.
Clinical use treatment gastrointestinal of the present invention Chinese medicine composition is treated all kinds of gastroenteropathy patient 869 examples, and existing result is as follows: this group case 869 examples, and male 443 examples, women 426 examples, the man is more than the woman; 2~83 years old age, in the majority with child and middle-older patient; The course of disease is the shortest 1 day, and is the longest 35 years.Wherein acute or chronic gastritis 215 people, enteritis 171 people, stomach burst 124, superficial gastritis 106, gastric acid flatulence, dyspepsia, inappetence 182 people, other gastroenteropathys 71 people.
Diagnostic criteria: with reference to " traditional Chinese medical science disease diagnosis criterion of therapeutical effect " of State Administration of Traditional Chinese Medicine's promulgation in 1994.
Therapeutic Method: based on powder, the adult directly takes with eliminating cold for resuscitation water, each 5 grams, and three times on the one, the child is cut down according to the circumstance.But also fry in shallow oil about 300 milliliters of water with 15 gram powders every day, divide and take for three times.
Efficacy assessment standard: draft according to " up-to-date domestic and international disease treatment standard " [3] efficacy assessment standard.
1. cure: the symptom complete obiteration, certain hour is not seen recurrence.
2. take a turn for the better: symptom partly disappears or alleviates.
3. do not heal: the symptom commentaries on classics of not getting better.
The result: clinical treatment 869 routine patients, cure 811 examples, 55 examples that take a turn for the better, 3 examples that do not heal, total effective rate is 99.7%, cure rate is 93.3%.
Treatment gastrointestinal Chinese medicine composition of the present invention, through acute toxicity test, the mice of getting 20 health is divided into 5 groups at random, and disposable heavy dose of oral administration was observed through 24 hours, and mice does not have the acute poisoning performance.The result shows, drug ratio safe without toxic side effect of the present invention.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment, but be not limited to embodiment.
Embodiment 1
The Chinese medicine composition of treatment gastroenteropathy of the present invention is made of the medicine of following weight proportion: 20 parts of Radix Ginseng Rubra, 18 parts of Poria, 17 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts of Rhizoma Chuanxiongs, 20 parts of Rhizoma Atractylodis, 20 parts of Rhizoma Cyperis, 20 parts of Massa Medicata Fermentata, 20 parts of Fructus Gardeniaees, 17 parts of Semen Arecaes, 18 parts of the Radix Aucklandiae, 12 parts in Radix Glycyrrhizae, Fructus Hordei Germinatus 5-8 part, 20 parts of Fructus Crataegis.
Embodiment 2
The Chinese medicine composition composition powders of treatment gastroenteropathy of the present invention is made of the medicine of following weight proportion: 10 parts of Radix Ginseng Rubra, 10 parts of Poria, 8 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Rhizoma Chuanxiongs, 10 parts of Rhizoma Atractylodis, 10 parts of Rhizoma Cyperis, 10 parts of Massa Medicata Fermentata, 10 parts of Fructus Gardeniaees, 10 parts of Semen Arecaes, 8 parts of the Radix Aucklandiae, 5 parts in Radix Glycyrrhizae, 5 parts in Fructus Hordei Germinatus, 10 parts of Fructus Crataegis.With above-mentioned totally ten three the flavor Chinese medicines by weight ratio mixed powder be broken into the powder packing make the treatment gastroenteropathy Chinese powder medicine.
Embodiment 3
The Chinese medicine composition of treatment gastroenteropathy of the present invention is made of the medicine of following weight proportion: 25 parts of Radix Ginseng Rubra, 23 parts of Poria, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 25 parts of Rhizoma Chuanxiongs, 25 parts of Rhizoma Atractylodis, 25 parts of Rhizoma Cyperis, 25 parts of Massa Medicata Fermentata, 25 parts of Fructus Gardeniaees, 23 parts of Semen Arecaes, 20 parts of the Radix Aucklandiae, 15 parts in Radix Glycyrrhizae, 8 parts in Fructus Hordei Germinatus, 25 parts of Fructus Crataegis.Above-mentioned 13 flavor Chinese medicines are mixed by weight ratio process decoction lixiviate-purification-concentrate-precipitation-drying-incapsulate shell to make the Chinese medicinal capsule agent for the treatment of gastroenteropathy.
Embodiment 4
The Chinese medicine composition of treatment gastroenteropathy of the present invention is made of the medicine of following weight proportion: 15 parts of Radix Ginseng Rubra, 16 parts of Poria, 14 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Rhizoma Chuanxiongs, 15 parts of Rhizoma Atractylodis, 15 parts of Rhizoma Cyperis, 15 parts of Massa Medicata Fermentata, 15 parts of Fructus Gardeniaees, 16 parts of Semen Arecaes, 14 parts of the Radix Aucklandiae, 8 parts in Radix Glycyrrhizae, 6 parts in Fructus Hordei Germinatus, 15 parts of Fructus Crataegis.Above-mentioned 13 flavor Chinese medicines are mixed by weight ratio, make the Chinese medicine oral liquid of treatment gastroenteropathy through decocting lixiviate-purification-concentrated-packing-sterilization-storage.

Claims (5)

1. a Chinese medicine composition for the treatment of gastroenteropathy is characterized in that, is made of the medicine of following weight proportion: Radix Ginseng Rubra 10-25 part, Poria 10-23 part, Rhizoma Atractylodis Macrocephalae 8-20 part, Rhizoma Chuanxiong 10-25 part, Rhizoma Atractylodis 10-25 part, Rhizoma Cyperi 10-25 part, Massa Medicata Fermentata 10-25 part, Fructus Gardeniae 10-25 part, Semen Arecae 10-23 part, Radix Aucklandiae 8-20 part, Radix Glycyrrhizae 5-15 part, Fructus Hordei Germinatus 5-8 part, Fructus Crataegi 10-25 part.
2. a treatment gastrointestinal Chinese medicinal composition preparation according to claim 1 is characterized in that, is prepared into powder, capsule and oral liquid.
3. treatment gastrointestinal Chinese medicinal composition preparation according to claim 2 is characterized in that, with Radix Ginseng Rubra 10-25 part, Poria 10-23 part, Rhizoma Atractylodis Macrocephalae 8-20 part, Rhizoma Chuanxiong 10-25 part, Rhizoma Atractylodis 10-25 part, Rhizoma Cyperi 10-25 part, Massa Medicata Fermentata 10-25 part, Fructus Gardeniae 10-25 part, Semen Arecae 10-23 part, Radix Aucklandiae 8-20 part, Radix Glycyrrhizae 5-15 part, Fructus Hordei Germinatus 5-8 part, Fructus Crataegi 10-25 part totally ten three flavor Chinese medicines by weight ratio mixed powder be broken into the powder packing and make treatment gastrointestinal Chinese medicine composition composition powders.
4. treatment gastrointestinal Chinese medicinal composition preparation according to claim 2, it is characterized in that, with Radix Ginseng Rubra 10-25 part, Poria 10-23 part, Rhizoma Atractylodis Macrocephalae 8-20 part, Rhizoma Chuanxiong 10-25 part, Rhizoma Atractylodis 10-25 part, Rhizoma Cyperi 10-25 part, Massa Medicata Fermentata 10-25 part, Fructus Gardeniae 10-25 part, Semen Arecae 10-23 part, Radix Aucklandiae 8-20 part, Radix Glycyrrhizae 5-15 part, Fructus Hordei Germinatus 5-8 part, Fructus Crataegi 10-25 part 13 flavor Chinese medicines mix by weight ratio, process decoction lixiviate-purification-concentrate-precipitation-drying-incapsulate shell to make the agent of treatment gastrointestinal Chinese medicinal composition capsules.
5. treatment gastrointestinal Chinese medicinal composition preparation according to claim 2, it is characterized in that, with Radix Ginseng Rubra 10-25 part, Poria 10-23 part, Rhizoma Atractylodis Macrocephalae 8-20 part, Rhizoma Chuanxiong 10-25 part, Rhizoma Atractylodis 10-25 part, Rhizoma Cyperi 10-25 part, Massa Medicata Fermentata 10-25 part, Fructus Gardeniae 10-25 part, Semen Arecae 10-23 part, Radix Aucklandiae 8-20 part, Radix Glycyrrhizae 5-15 part, Fructus Hordei Germinatus 5-8 part, Fructus Crataegi 10-25 part 13 flavor Chinese medicines mix by weight ratio, make treatment gastrointestinal Chinese medicine composition oral liquid formulations through decocting lixiviate-purification-concentrated-packing-sterilization-storage.
CN2010101430136A 2010-04-09 2010-04-09 Traditional Chinese medicinal composition for treating gastrointestinal tract and preparation thereof Expired - Fee Related CN101797347B (en)

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102125660A (en) * 2010-12-24 2011-07-20 朱西杰 Traditional Chinese medicine sustained-release micro granules stomach and intestine partner for protecting and strengthening functions of stomach and intestine
CN102526655A (en) * 2011-10-28 2012-07-04 文艺 Stomach-invigorating and parasite-expelling medicine for animals
CN102772670A (en) * 2012-08-17 2012-11-14 张守实 Traditional Chinese medicine composition for treating superficial gastritis
CN104491816A (en) * 2014-12-30 2015-04-08 陈满锦 Application of traditional Chinese medicinal composition in preparation of medicine for treating chronic gastroenteritis
CN105056196A (en) * 2015-09-02 2015-11-18 河南百年康鑫药业有限公司 Medicine composition for treating peptic ulcer and preparing method thereof
CN108187009A (en) * 2018-02-11 2018-06-22 海南大洲金丝燕生态农业开发有限公司 A kind of Chinese medicine composition for being used to treat Java esculent swift gasteremphraxis
CN112755139A (en) * 2021-01-26 2021-05-07 范小楠 Stomach-nourishing traditional Chinese medicine composition and preparation method thereof
CN113230362A (en) * 2021-06-02 2021-08-10 李纪文 Stomach medicine and preparation method thereof
CN114712446A (en) * 2021-01-05 2022-07-08 金陵药业股份有限公司 Traditional Chinese medicine composition and preparation for treating stomach diseases and preparation method thereof
JP2023003756A (en) * 2021-06-24 2023-01-17 広東省中医院 Herbal composition for improving gastrointestinal nutrient absorption, method for manufacturing the same and use thereof

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108112987A (en) * 2017-12-12 2018-06-05 广州农信饲料有限公司 A kind of functional preparation for adjusting gastrointestinal health and its preparation method and application

Citations (2)

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Publication number Priority date Publication date Assignee Title
CN1390579A (en) * 2002-05-16 2003-01-15 段登奎 'Weifukang' tablet for treating gastrosis
CN1772248A (en) * 2005-10-27 2006-05-17 于勇春 Gastric ulcer treating medicine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1390579A (en) * 2002-05-16 2003-01-15 段登奎 'Weifukang' tablet for treating gastrosis
CN1772248A (en) * 2005-10-27 2006-05-17 于勇春 Gastric ulcer treating medicine

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102125660A (en) * 2010-12-24 2011-07-20 朱西杰 Traditional Chinese medicine sustained-release micro granules stomach and intestine partner for protecting and strengthening functions of stomach and intestine
CN102526655A (en) * 2011-10-28 2012-07-04 文艺 Stomach-invigorating and parasite-expelling medicine for animals
CN102526655B (en) * 2011-10-28 2014-01-01 玛曲县黄河首曲药源开发有限公司 Stomach-invigorating and parasite-expelling medicine for animals
CN102772670A (en) * 2012-08-17 2012-11-14 张守实 Traditional Chinese medicine composition for treating superficial gastritis
CN104491816A (en) * 2014-12-30 2015-04-08 陈满锦 Application of traditional Chinese medicinal composition in preparation of medicine for treating chronic gastroenteritis
CN105056196B (en) * 2015-09-02 2019-03-08 河南百年康鑫药业有限公司 A kind of pharmaceutical composition and preparation method thereof for treating peptic ulcer
CN105056196A (en) * 2015-09-02 2015-11-18 河南百年康鑫药业有限公司 Medicine composition for treating peptic ulcer and preparing method thereof
CN108187009A (en) * 2018-02-11 2018-06-22 海南大洲金丝燕生态农业开发有限公司 A kind of Chinese medicine composition for being used to treat Java esculent swift gasteremphraxis
CN114712446A (en) * 2021-01-05 2022-07-08 金陵药业股份有限公司 Traditional Chinese medicine composition and preparation for treating stomach diseases and preparation method thereof
CN112755139A (en) * 2021-01-26 2021-05-07 范小楠 Stomach-nourishing traditional Chinese medicine composition and preparation method thereof
CN113230362A (en) * 2021-06-02 2021-08-10 李纪文 Stomach medicine and preparation method thereof
JP2023003756A (en) * 2021-06-24 2023-01-17 広東省中医院 Herbal composition for improving gastrointestinal nutrient absorption, method for manufacturing the same and use thereof
JP7394811B2 (en) 2021-06-24 2023-12-08 広東省中医院 Chinese herbal medicine composition for improving nutrient absorption in the gastrointestinal tract, its production method and use

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