CN102526655A - Stomach-invigorating and parasite-expelling medicine for animals - Google Patents
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Abstract
The invention discloses a stomach-invigorating and parasite-expelling medicine for animals. Various oral preparations are prepared from Tibetan medicine areca-nut, gypsum rubrum, liquorice, atractylodes lancea, dried ginger, Tibet inula, pomegranate, hawthorn, medicated leaven and pterocephalus hookeri by the conventional preparation process for veterinary medicines. The clinical test result shows that the stomach-invigorating and parasite-expelling medicine has the effects of promoting digestion, eliminating stasis, warming middle energizer, dispelling cold, regulating vital energy, invigorating stomach, killing various intestinal parasites of the animals and the like, can be used for treating digestive diseases of the animals caused by various reasons and gastrointestinal type cold and expelling the intestinal parasites in the animals and the like. Under the disease-free condition, the stomach-invigorating and parasite-expelling medicine has the effects of resisting bacterial, promoting growth and the like, can be used for enhancing fat maintenance, fattening and weight increment of flocks and herds in spring and autumn, contributes to increase of slaughter rate and has great significance for reducing grassland pressure, preventing grassland deterioration, relieving grass demand contradiction, maintaining ecological balance of the grassland and promoting virtuous cycle of grassland animal husbandry.
Description
Technical field
The invention belongs to field of veterinary, relate to a kind of animal anthelmintic medicine that is good for the stomach that is used for, be mainly used in the digestive disease that the treatment animal causes because of a variety of causes, common cold of gastrointestinal type and drive diseases such as controlling the intravital Enterozoa of animal.
Background technology
Animal husbandry is the pillar industry specialty industries of China Tibetan area, and the sound development of animal husbandry is directly connected to the Tibetan area social stability and the masses of farmers and herdsmen's living standard.Production high-quality, the farming and pastoral area of the also timely supply of medicine for animals efficiently; Can improve the veterinary medicament situation of bringing because of factors such as the Tibetan area are remote, traffic is less-developed in short supply effectively; Make veterinary medicament in time treat livestock disease; Reduce the Died Of Disease rate, promote the Tibetan area Developing of Animal Industry, strengthen peasants and herdsmen's income.In recent years, along with the production-scale continuous expansion of aquaculture, the number of animals raised of domestic animal surge.Livestock products receive for a long time that medicine is residual to be shown with the residual pollution defective of epidemic disease day by day, have become the significant obstacle that influenced the Tibetan area animal husbandry development.
In Alpine-arctic Pastoral, usually because of season and temperature Change, the domestic animal gastrointestinal tract happens occasionally, and the spy is that spring and summer replaces season fully, because of after domestic animal eats into the frost feedstuff, not only causes gastrointestinal disease, and the secondary other diseases, causes the domestic animal mortality.Epidemiological study shows, the grow up sickness rate of yak of Tibetan area is 23.5%, and mortality rate is 12.5%, and it is slow that disease symptom mainly is glandular stomach, and grainsick, and the secondary other diseases causes dead aggravation, appears at spring and summer, the time when autumn turns into winter mostly is in the cold weather.The mortality rate of yak calf is 15.48%, and mostly disease symptom is ascites, appears at mostly after the calf wean.This shows that gastroenteropathy is one of principal element that influences the growth of animal cub, growth and adults health.In addition; The infection of multiple Enterozoas such as cestode and ascarid, ancylostome also is a common disease the most in the herds; It is seriously influencing normal growth and the health of animal; Therefore, developing a kind of safe, inexpensive and curative effect anthelmintic drug that is good for the stomach preferably, is the technical barrier that needs to be resolved hurrily in the present animal husbandry development.
Summary of the invention
The purpose of this invention is to provide a kind of animal anthelmintic medicine that is good for the stomach that is used for.
The present invention is a kind of to be used for the animal anthelmintic medicine that is good for the stomach, and is to be crude drug with Tibetan medicine Semen Arecae, Mirabilitum crystallina, Radix Glycyrrhizae, Rhizoma Atractylodis, Rhizoma Zingiberis, Radix Inulae, Punica granatum L., Fructus Crataegi, Massa Medicata Fermentata, Herba pterocephali ten flavors, the various oral preparations of processing by the conventional preparation technology of veterinary drug.
In the pharmaceutical formulation of the present invention, Semen Arecae (hiding the ancient territory of name), nature and flavor are bitter; Hot; Temperature.Return stomach; Large intestine channel.Effect: expelling intestinal worms and removing food stagnancy; Promoting the circulation of QI to induce diuresis; Cure mainly: 1. anthelmintic: multiple Enterozoas such as main expelling tenia and ascarid, ancylostome.2. circulation of qi promoting removing food stagnancy: kind stagnation of QI due to dyspepsia distension and the stagnant dysentery stomachache controlled.3. inducing diuresis to remove edema: be suitable for the edema excess syndrome.
Mirabilitum crystallina (hiding the name monarch has a rest), nature and flavor: hot, salty, cold.Gui Jing: the heart, stomach, kidney channel.Effect: resolving heat and reducing pathogenic fire, sharp key, detumescence.Has the effect of toxicity, the strong and property of medicine of being in harmonious proportion.Cure mainly: row calentura when controlling, long-pending hot excessive thirst, vomiting and diarrhoea, edema, urine retention, bleeding from the gum, erysipelas, scald.
Radix Glycyrrhizae (hiding the fragrant A Er of name), nature and flavor: sweet, flat.Gui Jing: GUIXIN, lung, spleen, stomach warp.Effect: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the mediation property of medicine.Cure mainly: be used for weakness of the spleen and stomach, laryngopharynx swelling and pain, the extremity contraction is anxious, too fat to move sore, cushion and alimentary toxicosis.
Fructus Crataegi (hiding name office day), nature and flavor: sour in the mouth, sweet, nontoxic, slightly warm in nature.Gui Jing: go into spleen, stomach warp.Effect: appetite-stimulating indigestion-relieving, change stagnant removing food stagnancy, promoting blood circulation to remove blood stasis, the circulation of qi promoting of reducing phlegm.Cure mainly: be used for retention of food and drink, long-pending abdominal mass is gathered, the resistance of abdominal distention feeling of fullness, the stasis of blood stomachache, phlegm retention, have loose bowels, discharging fresh blood stool, lochiorrhea antibacterially waits effect.
Rhizoma Atractylodis (hiding the name west), nature and flavor: hot, bitter, temperature.Gui Jing: return spleen, stomach, Liver Channel.Effect: drying damp and strengthening spleen, dispel the wind, cold expelling, make eye bright.Cure mainly: be used for distension and fullness in the abdomen, have loose bowels, edema, rheumatic arthralgia, anemofrigid cold, nyctalopia nyctalopia.
Radix Inulae (hiding name Ma Na), nature and flavor: hot, bitter, temperature.Gui Jing: return spleen, stomach, gallbladder, tri-jiao channel.Effect: circulation of qi promoting, pain relieving, relieving distension.Cure mainly: be used for the tripe abdomen pain of stagnation of QI in spleen and stomach, inappetence, abdominal swelling, stomachache, dysentery tenesmus.
Rhizoma Zingiberis (hiding the name loud, high-pitched sound adds), nature and flavor: suffering, heat.Gui Jing: return spleen, stomach, kidney, the heart, lung meridian.Effect: warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, the dampness expectorant.Cure mainly: hinder the water-cooled pain, vomiting is had loose bowels, the cold extremities faint pulse, and phlegm retention is breathed with cough.
Punica granatum L. (hiding name match folding), nature and flavor: sour in the mouth is puckery, warm in nature, nontoxic.Gui Jing: stomach, large intestine channel.Effect: deficiency and coldness chronic diarrhea, the relieving dyspepsia of promoting the production of body fluid.Cure mainly: enteritis, have blood in stool, proctoptosis, detoxifcation, taeniasis, cooling etc.
Massa Medicata Fermentata (have another name called: Massa Medicata Fermentata, hide name five agates), nature and flavor: sweetness, little be with pungent, warm partially.Gui Jing: go into spleen, stomach warp.Effect: insufficiency of the spleenly do not change promoting digestion and removing stagnation.Cure mainly: the stomachache, diarrhoea, inappetence, the abdominal part that cause because of insufficiency of the spleen dyspepsia are vexed bloated.
Herba pterocephali (hide the name prescription protects more), nature and flavor: hardship, cold, slightly poisonous.Gui Jing: return stomach, kidney channel.Effect: detoxifcation removes pestilence, clearing away heat to cure dysentery, and blood stasis dispelling dispels the wind.Cure mainly: be used to treat pestilent toxicity, new and old epidemic febrile disease, dirty onychonosus, pyretic arthralgia disease, dysentery, rheumatic arthritis, intestinal colic etc.
The present invention makes up above-mentioned ten flavors; The drug effect of each crude drug is played altogether; Work in coordination with and realize its dyspepsia and intestinal stasis relieving, regulating qi-flowing for strengthening spleen, warming middle-JIAO to dispel cold, the wide intestinal of dispelling the stagnated QI, drive the effect of controlling the gastrointestinal tract nematicide; Thereby reach the digestive disease that causes because of a variety of causes of treatment animal, common cold of gastrointestinal type and drive diseases such as controlling the intravital Enterozoa of animal.
Experiment showed, that in a large number in the medicine of the present invention, each crude drug is filled a prescription in following scope, all can reach dyspepsia and intestinal stasis relieving, warming middle-JIAO to dispel cold, regulating qi-flowing for strengthening spleen, multiple parasitic effect in the animal repelling body:
15～50 parts of Semen Arecaes, 10～35 parts of Mirabilitum crystallinas, 5～35 parts in Radix Glycyrrhizae, 10～35 parts of Rhizoma Atractylodis, 10～50 parts of Rhizoma Zingiberiss, 10～35 parts of Radix Inulae, 10～50 parts of Punica granatum L.s, 15～50 parts of Fructus Crataegis, 9～30 parts of Massa Medicata Fermentata, 13～50 parts of Herba pterocephali.
Optimum ratio is: 20～30 parts of Semen Arecaes, 20～30 parts of Mirabilitum crystallinas, 15～25 parts in Radix Glycyrrhizae, 20～25 parts of Rhizoma Atractylodis, 20～40 parts of Rhizoma Zingiberiss, 20～30 parts of Radix Inulae, 20～40 parts of Punica granatum L.s, 20～35 parts of Fructus Crataegis, 15～20 parts of Massa Medicata Fermentata, 20～35 parts of Herba pterocephali.
Best proportioning is: 30 parts of Semen Arecaes, 15 parts of Mirabilitum crystallinas, 15 parts in Radix Glycyrrhizae, 20 parts of Rhizoma Atractylodis, 20 parts of Rhizoma Zingiberiss, 20 parts of Radix Inulae, 15 parts of Punica granatum L.s, 30 parts of Fructus Crataegis, 20 parts of Massa Medicata Fermentata, 30 parts of Herba pterocephali.
Said ratio is weight portion meter all.
Usage: eliminating cold for resuscitation water is irritated clothes.
Consumption: horse cattle: 105 ~ 250g; Pig sheep: 30 ~ 60g.
Describe through the effect of clinical observation below drug-treated animals dyspepsia and intestinal stasis relieving of the present invention, warming middle-JIAO to dispel cold and animal repelling endoparasite.Be clinical observation on the therapeutic effect statistics below to the Tibetan area yak:
1. supply laboratory animal and experimental drug
1.1 the selection of model household
Select 9 tame raisers' each 40 of adult yak (3 years old mean age) and the yak calves at 6 monthly ages, totally 80 as model household, carries out the clinical pharmacology effect observation.
1.2 test drug
Powder agent medicine (hiding name: Sai Aijixia ties) by formulation of the present invention.
2 test methods
Supply examination composition year yak and yak calf to be divided into four groups, supply each 20 of examination groups, each 20 of matched groups.Supply the examination group to irritate clothes, not medication of matched group.One day twice, one time 150～250 gram of cattle of growing up, one time 30～60 gram of yak calf, for three days on end.The yak that grows up is irritated clothes October, and 6 monthly ages of yak calf are irritated clothes, before irritating clothes, measures body weight simultaneously, and irritate clothes and measured body weight in back 2 months again, and statistics yak body weight situation and survival rate.
3 result of the tests: table 1,2 is seen in the statistical result of yak body weight situation and survival rate.
Table 1 yak calf body weight gain situation statistical table unit: kilogram)
The table 2 yak body weight gain situation statistical table of growing up: (unit: kilogram)
The statistics of table 1 and table 2 shows, the yak that grows up supplies the examination group to many weightening finish 5.14 kg than matched group, and the yak calf supplies the examination group to many weightening finish 7.35 kg than matched group.Through t check significant difference (P＜0.05).Supply the adult yak of examination composition year yak and matched group to measure the situation of body weight the same period at December; Supply the examination group obvious because of efficiency of feed utilization improves 20%～30% average weight gain effect, some individuality of matched group has the phenomenon of losing flesh, because of December is in hay season; Efficiency of feed utilization is poor, causes to lose flesh.
Table 3,4 is respectively the statistics that the sheep effect is put in yak calf and adult yak field in a suitable place to breed: test drug and test method are the same.
Statistical effect is put in table 3 yak calf field in a suitable place to breed
Statistical effect is put in the adult yak field of table 4 in a suitable place to breed
Table 3,4 statistics show, supplies the examination group to take the present invention and be good for the stomach behind the anthelmintic drug, greatly reduces the generation of gastroenteropathy, thereby greatly reduce the mortality rate of the yak that grows up, improved the survival rate of yak calf.
In sum; The anthelmintic drug that is good for the stomach of the present invention have dyspepsia and intestinal stasis relieving, warming middle-JIAO dispel cold, regulate the flow of vital energy be good for the stomach and the kill animals intestinal in effect such as multiple parasite; Can be used for treating the digestive disease that animal causes because of a variety of causes, common cold of gastrointestinal type and drive diseases such as controlling the intravital Enterozoa of animal.Under anosis situation, have effects such as antibiotic guarantor's growth promotion, can be used to strengthen the spring and autumn cattle and sheep the bodyguard, fatten, increase weight; Help increasing the number of heads of livestock for sale; To alleviating grassland pressure, prevent deterioration of grasslands, alleviating grass needs contradiction; Keep the grassland ecological balance, the benign cycle that promotes grassland agriculture has crucial meaning.In addition, crude drug of the present invention relies on abundant Tibetan medicine aptitude source, Tibetan area, its cheapness, high-quality, safety, reliable, and stable curative effect has very big development potentiality.
The specific embodiment
Further specify through the preparation of specific embodiment below medicine of the present invention.
The preparation of embodiment 1, powder agent medicine
Prescription: in weight portion
30 parts of Semen Arecaes, 15 parts of Mirabilitum crystallinas, 15 parts in Radix Glycyrrhizae, 20 parts of Rhizoma Atractylodis, 20 parts of Rhizoma Zingiberiss, 20 parts of Radix Inulae, 15 parts of Punica granatum L.s, 30 parts of Fructus Crataegis, 20 parts of Massa Medicata Fermentata, 30 parts of Herba pterocephali.
Technology: by the common process preparation of preparation animal powder agent medicine.
The preparation of embodiment 2, granules medicine
Prescription: in weight portion
15 parts of Semen Arecaes, 10 parts of Mirabilitum crystallinas, 5 parts in Radix Glycyrrhizae, 10 parts of Rhizoma Atractylodis, 10 parts of Rhizoma Zingiberiss, 35 parts of Radix Inulae, 50 parts of Punica granatum L.s, 50 parts of Fructus Crataegis, 30 parts of Massa Medicata Fermentata, 50 parts of Herba pterocephali.
Technology: by the common process preparation of preparation animal granules medicine.
The preparation of embodiment 3, capsule medicine
Prescription: in weight portion
50 parts of Semen Arecaes, 35 parts of Mirabilitum crystallinas, 35 parts in Radix Glycyrrhizae, 35 parts of Rhizoma Atractylodis, 50 parts of Rhizoma Zingiberiss, 10 parts of Radix Inulae, 10 parts of Punica granatum L.s, 15 parts of Fructus Crataegis, 9 parts of Massa Medicata Fermentata, 13 parts of Herba pterocephali.
Technology: by the common process preparation of preparation animal capsule medicine.
The preparation of embodiment 4, pill medicine
Prescription: in weight portion
15 parts of Semen Arecaes, 10 parts of Mirabilitum crystallinas, 5 parts in Radix Glycyrrhizae, 10 parts of Rhizoma Atractylodis, 10 parts of Rhizoma Zingiberiss, 10 parts of Radix Inulae, 10 parts of Punica granatum L.s, 15 parts of Fructus Crataegis, 9 parts of Massa Medicata Fermentata, 13 parts of Herba pterocephali.
Technology: by the common process preparation of preparation animal pill medicine.
The preparation of embodiment 5, oral solutions medicine
Prescription: in weight portion
50 parts of Semen Arecaes, 35 parts of Mirabilitum crystallinas, 35 parts in Radix Glycyrrhizae, 35 parts of Rhizoma Atractylodis, 50 parts of Rhizoma Zingiberiss, 35 parts of Radix Inulae, 50 parts of Punica granatum L.s, 50 parts of Fructus Crataegis, 30 parts of Massa Medicata Fermentata, 50 parts of Herba pterocephali.
Technology: by the common process preparation of preparation animal oral solutions medicine.
Claims (3)
1. one kind is used for the animal anthelmintic medicine that is good for the stomach, and is the oral preparations that is prepared from following bulk drugs:
15～50 parts of Semen Arecaes, 10～35 parts of Mirabilitum crystallinas, 5～35 parts in Radix Glycyrrhizae, 10～35 parts of Rhizoma Atractylodis, 10～50 parts of Rhizoma Zingiberiss, 10～35 parts of Radix Inulae, 10～50 parts of Punica granatum L.s, 15～50 parts of Fructus Crataegis, 9～30 parts of Massa Medicata Fermentata, 13～50 parts of Herba pterocephali.
2. be used for the animal anthelmintic medicine that is good for the stomach according to claim 1, it is characterized in that: the weight proportion of said each crude drug is:
20～30 parts of Semen Arecaes, 20～30 parts of Mirabilitum crystallinas, 15～25 parts in Radix Glycyrrhizae, 20～25 parts of Rhizoma Atractylodis, 20～40 parts of Rhizoma Zingiberiss, 20～30 parts of Radix Inulae, 20～40 parts of Punica granatum L.s, 20～35 parts of Fructus Crataegis, 15～20 parts of Massa Medicata Fermentata, 20～35 parts of Herba pterocephali.
3. be used for the animal anthelmintic medicine that is good for the stomach according to claim 1, it is characterized in that: the weight proportion of said each crude drug is:
30 parts of Semen Arecaes, 15 parts of Mirabilitum crystallinas, 15 parts in Radix Glycyrrhizae, 20 parts of Rhizoma Atractylodis, 20 parts of Rhizoma Zingiberiss, 20 parts of Radix Inulae, 15 parts of Punica granatum L.s, 30 parts of Fructus Crataegis, 20 parts of Massa Medicata Fermentata, 30 parts of Herba pterocephali.
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| CN105616808A (en) * | 2014-10-27 | 2016-06-01 | 河南惠通天下生物工程有限公司 | Traditional Chinese veterinary drug with effects of stomach invigorating and deworming, and preparation method thereof |
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| CN105616808A (en) * | 2014-10-27 | 2016-06-01 | 河南惠通天下生物工程有限公司 | Traditional Chinese veterinary drug with effects of stomach invigorating and deworming, and preparation method thereof |
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