CN101766774B - Chinese medicine composite for treating duodenal ulcer and preparation method thereof - Google Patents

Chinese medicine composite for treating duodenal ulcer and preparation method thereof Download PDF

Info

Publication number
CN101766774B
CN101766774B CN2010101408594A CN201010140859A CN101766774B CN 101766774 B CN101766774 B CN 101766774B CN 2010101408594 A CN2010101408594 A CN 2010101408594A CN 201010140859 A CN201010140859 A CN 201010140859A CN 101766774 B CN101766774 B CN 101766774B
Authority
CN
China
Prior art keywords
parts
radix
chinese medicine
medicine composition
fructus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2010101408594A
Other languages
Chinese (zh)
Other versions
CN101766774A (en
Inventor
王峰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiyi Hepu Beijing Research Institute of Traditional Chinese Medicine Co Ltd
Original Assignee
Taiyi Hepu Beijing Research Institute of Traditional Chinese Medicine Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiyi Hepu Beijing Research Institute of Traditional Chinese Medicine Co Ltd filed Critical Taiyi Hepu Beijing Research Institute of Traditional Chinese Medicine Co Ltd
Priority to CN2010101408594A priority Critical patent/CN101766774B/en
Publication of CN101766774A publication Critical patent/CN101766774A/en
Application granted granted Critical
Publication of CN101766774B publication Critical patent/CN101766774B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

The invention discloses a new Chinese medicine composite for treating duodenal ulcer and a preparation method thereof. The Chinese medicine composite mainly comprises the following active pharmaceutical ingredients of stir-fried frankincense, stir-fried myrrh, semen coicis, lignum dalbergiae odoriferae, pericarpium citri reticulatae, fructus hordei germinatus, medicated leaven, radix trichosanthis, tuckahoe, rhizoma coptidis, baikal skullcap root, radix sophorae flavescentis, densefruit pittany root-bark, Chinese wolfberry root-bark, white flower patrinia herb, fructus amomi, lignum aquilariae resinatum, aspongopus, rhizoma corydalis, raw radix astragali, rhizoma dioscoreae, radix codonopsis and white peony root, and the like. The Chinese medicine composite can be prepared to be any common oral preparation according to the conventional Chinese medicine preparation method. The Chinese medicine composite can obviously improve epigastric pain, vague pain and complaint, hemorrhea, gastricperforation, obstruction and the like, which has definite clinical effect, obvious curative effect and fast desired effect. Due to the combination of the medicines both as food and medicine accordingto state-promulgated pharmacopoeia, the Chinese medicine composite of the invention has the advantages of low cost, basically no toxic side effect and the like.

Description

A kind of Chinese medicine composition for the treatment of duodenal ulcer and preparation method thereof
Technical field
[0001] the present invention relates to a kind of Chinese medicine composition for the treatment of duodenal ulcer.Relating in particular to a kind of is the Chinese medicine composition and preparation method thereof of the treatment duodenal ulcer of crude drug with the Chinese herbal medicine.
Background technology
Duodenal ulcer is meant the chronic ulcer disease that sees gastrointestinal tract and gastric juice contact site, is often caused by factors such as gastritis, gastric ulcer, heredity, bad habit and spiritual emotion and medicine irritations.Syndromes such as main clinical manifestation is an epigastrium pain, also can show as only dull pain discomfort when hunger, and primary disease control is improper massive hemorrhage, gastric perforation to occur, block.The Chang Fanfu outbreak, even medical history can reach several years more than ten years, outbreak has seasonality, how in autumn and winter or morbidity at the end of winter and the beginning of spring, the clinical onset rate has the trend of continuous rising in recent years.
Modern medicine is at clinical a certain symptom treatment, often fall flat, can not find suitable Therapeutic Method, in order to overcome above-mentioned defective, the present invention is based on the differential diagnosis of diseases and the dialectical principle that combines of Chinese traditional treatment duodenal ulcer, treating both the principal and secondary aspects of a disease, deficiency and excess is also controlled, inside and outside logical accent, emergency is taken in concurrently, filter out the natural plant of dispersing the stagnated liver-QI for regulating the stomach, softening the hard mass and change, relieving gastric hyperacidity to alleviate stomachache, the granulation promoting of regulating the flow of vital energy,, be prepared from according to certain weight proportion according to the theory of Chinese medical science prescription.A kind of Chinese medicine composition of evident in efficacy, with low cost, treatment duodenal ulcer that toxic and side effects is minimum is provided.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage forms, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be: pill, capsule, tablet, powder, granule or oral liquid etc.
Summary of the invention
Technical problem to be solved by this invention is assorted to overcome above-described shortcoming, and a kind of Chinese medicine composition of treatment duodenal ulcer of evident in efficacy, with low cost, almost non-toxic side effect is provided.
The technical problem of the desired solution of the present invention realizes by following technological approaches.
A kind of Chinese medicine composition for the treatment of duodenal ulcer of the present invention, the component of main following weight portion is formed:
1~50 part of Olibanum (processed), 1~50 part of Myrrha (processed), 1~150 part of Semen Coicis, 1~100 part of Lignum Dalbergiae Odoriferae, 1~120 part of Pericarpium Citri Reticulatae, 1~100 part of Fructus Aurantii Immaturus, 1~100 part of Massa Medicata Fermentata, 1~120 part in Poria, 1~100 part in Fructus Hordei Germinatus, 1~100 part of Semen Arecae Prepareta, 1~100 part of Fructus Setariae Germinatus, 1~120 part of Radix Trichosanthis, 1~50 part of Fructus Gardeniae, 1~120 part of Rhizoma Coptidis, 1~120 part of Radix Scutellariae, 1~100 part of Radix Sophorae Flavescentis, 1~100 part of Cortex Fraxini, 1~100 part of Cortex Dictamni, 1~100 part of Radix Scrophulariae, 1~100 part of Radix Paeoniae Rubra, 1~100 part of the Radix Paeoniae Alba, 1~100 part of Eupolyphaga Seu Steleophaga, 1~100 part of Lignum Sappan, 1~50 part of Sanguis Draxonis, 1~50 part in catechu, 1~50 part of Herba Artemisiae Anomalae, 1~300 part of Radix Astragali, 1~150 part of Rhizoma Dioscoreae, 1~100 part in Radix Glycyrrhizae, 1~100 part of the Rhizoma Atractylodis Macrocephalae, 1~120 part of Radix Codonopsis, 1~120 part of Radix Rehmanniae Preparata, 1~150 part of Radix Angelicae Sinensis, 1~50 part of Semen Myristicae, 1~50 part of Semen Euryales, 1~100 part of Limonitum.
Be preferably:
15 parts of Olibanum (processed), 15 parts of Myrrha (processed)s, 30 parts of Semen Coiciss, 10 parts of Lignum Dalbergiae Odoriferaes, 50 parts of Pericarpium Citri Reticulataes, 30 parts of Fructus Aurantii Immaturuss, 30 parts of Massa Medicata Fermentata, 40 parts in Poria, 30 parts in Fructus Hordei Germinatus, 10 parts of Semen Arecae Preparetas, 20 parts of Fructus Setariae Germinatuss, 30 parts of Radix Trichosanthis, 10 parts of Fructus Gardeniaes, 10 parts of Rhizoma Coptidis, 20 parts of Radix Scutellariaes, 15 parts of Radix Sophorae Flavescentiss, 15 parts of Cortex Fraxinis, 15 parts of Cortex Dictamni, 20 parts of Radix Scrophulariaes, 15 parts of Radix Paeoniae Rubra, 30 parts of the Radix Paeoniae Albas, 10 parts of Eupolyphaga Seu Steleophagas, 20 parts of Lignum Sappans, 10 parts of Sanguis Draxonis, 10 parts in catechu, 15 parts of Herba Artemisiae Anomalaes, 100 parts of Radix Astragali, 30 parts of Rhizoma Dioscoreaes, 10 parts in Radix Glycyrrhizae, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Radix Codonopsis, 20 parts of Radix Rehmanniae Preparata, 30 parts of Radix Angelicae Sinensis, 15 parts of Semen Myristicaes, 15 parts of Semen Euryaless, 20 parts of Limonitum.
The weight portion consumption of each component of Chinese medicine composition of the present invention can also be:
1~100 part of Radix Arnebiae (Radix Lithospermi), 1~120 part of Flos Lonicerae, 1~100 part of Herba Violae, 1~100 part of Fructus Forsythiae, 1~120 part of Herba Taraxaci, 1~50 part of Flos Chrysanthemi Indici, 1~120 part of Herba Houttuyniae, 1~120 part of Herba Patriniae, 1~120 part of Radix Sophorae Tonkinensis, 1~60 part of Herba Lobeliae Chinensis, 1~50 part of Pseudobulbus Cremastrae Seu Pleiones, 1~120 part of Cortex Lycii, 1~100 part of Aloe, 1~100 part of Radix Et Rhizoma Rhei, 1~100 part of Rhizoma Atractylodis, 1~100 part of Cortex Magnoliae Officinalis, 1~100 part of Herba Eupatorii, 1~100 part of Fructus Amomi, 1~50 part of Lignum Aquilariae Resinatum, 1~120 part of the Radix Linderae, 1~100 part of Bulbus Allii Macrostemonis, 1~50 part of Aspongopus, 1~50 part of Endothelium Corneum Gigeriae Galli, 1~120 part of Rhizoma Corydalis, 1~100 part in Rhizoma Curcumae Longae, 1~120 part of Radix Polygoni Multiflori.
Be preferably:
20 parts of Radix Arnebiae (Radix Lithospermi)s, 20 parts of Flos Loniceraes, 15 parts of Herba Violaes, 15 parts of Fructus Forsythiaes, 20 parts of Herba Taraxaci, 15 parts of Flos Chrysanthemi Indicis, 15 parts of Herba Houttuyniae, 15 parts of Herba Patriniae, 20 parts of Radix Sophorae Tonkinensiss, 15 parts of Herba Lobeliae Chinensis, 15 parts of Pseudobulbus Cremastrae Seu Pleioness, 20 parts of Cortex Lycii, 15 parts of Aloes, 15 parts of Radix Et Rhizoma Rhei, 10 parts of Rhizoma Atractylodis, 30 parts of Cortex Magnoliae Officinalis, 10 parts of Herba Eupatoriis, 15 parts of Fructus Amomis, 10 parts of Lignum Aquilariae Resinatum, 20 parts of the Radixs Linderae, 15 parts of Bulbus Allii Macrostemonis, 15 parts of Aspongopuss, 15 parts of Endothelium Corneum Gigeriae Galli, 30 parts of Rhizoma Corydalis, 10 parts in Rhizoma Curcumae Longae, 20 parts of Radix Polygoni Multiflori.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage form, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be pill, capsule, tablet, powder, granule or oral liquid etc.
Chinese medicine composition of the present invention is opened one's minds based on traditional Chinese medical science the five internal organs differentiation of syndromes of YIN and YANG guiding principle, in conjunction with safe one and Pu innovation theory system " ten thousand diseases ascent theory ", " the five internal organs differentiation of syndromes of YIN and YANG guiding principle ", " three-dimensional conservation regulation and control rule " and clinical treatment " pairing principle " are as instructing, take place in conjunction with disease, development and the rule that changes, classify according to the original new drug system, formation is monarch with " the five internal organs basic function is adjusted; equilibrium between yin and yang coordination side ", " the main pathogenesis of the five internal organs adjustment side " is minister, " therapy of serious disease side " is assistant, " clinical fundamental symptoms symptomatic treatment side " Chinese medicine patent medicine " original new drug system " for making.
The used herbal raw material medicine of the present invention all can be buied from the Chinese medicine shop, and its specification meets national medical standard.
Usage and dosage: dosage of the present invention depends on concrete dosage form, factors such as patient age, body weight, health status.As guidance: for oral administration: 1) capsule: obey 2~5 every day three times at every turn, every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2~4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.5) powder: every day three times, each 2~4 grams, warm water takes.
The treatment that the present invention is directed to duodenal ulcer patients is very effective, various crude drug are coordinated mutually can play together and are at utmost brought into play drug effect, can effectively improve the self-coordination ability of patient's body, significantly improve function and clinical subjective symptoms, have advantage such as have no side effect, expense is lower in addition.
The specific embodiment
Further describe the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never are limited to the present invention.
The preparation of [embodiment 1] capsule
Take by weighing each raw material by following weight portion: 15 parts of Olibanum (processed), 15 parts of Myrrha (processed)s, 30 parts of Semen Coiciss, 10 parts of Lignum Dalbergiae Odoriferaes, 50 parts of Pericarpium Citri Reticulataes, 30 parts of Fructus Aurantii Immaturuss, 30 parts of Massa Medicata Fermentata, 40 parts in Poria, 30 parts in Fructus Hordei Germinatus, 10 parts of Rhizoma Coptidis, 20 parts of Radix Scutellariaes, 15 parts of Radix Sophorae Flavescentiss, 15 parts of Cortex Fraxinis, 15 parts of Cortex Dictamni, 30 parts of the Radix Paeoniae Albas, 10 parts of Eupolyphaga Seu Steleophagas, 20 parts of Lignum Sappans, 10 parts of Sanguis Draxonis, 10 parts in catechu, 15 parts of Herba Artemisiae Anomalaes, 100 parts of Radix Astragali, 30 parts of Rhizoma Dioscoreaes, 10 parts in Radix Glycyrrhizae, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Radix Codonopsis, 20 parts of Radix Rehmanniae Preparata, 30 parts of Radix Angelicae Sinensis, 15 parts of Semen Myristicaes, 15 parts of Semen Euryaless, 20 parts of Limonitum, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 20 parts of Flos Loniceraes, 15 parts of Herba Violaes, 15 parts of Fructus Forsythiaes, 20 parts of Herba Taraxaci, 15 parts of Herba Patriniae, 30 parts of Cortex Magnoliae Officinalis, 15 parts of Fructus Amomis, 10 parts of Lignum Aquilariae Resinatum.
Grind into after each component mixing with above-mentioned weight and incapsulate promptly after fine powder is crossed 1500 mesh sieves.
The preparation of [embodiment 2] granule
Take by weighing each raw material by following weight portion: 15 parts of Olibanum (processed), 15 parts of Myrrha (processed)s, 30 parts of Semen Coiciss, 10 parts of Lignum Dalbergiae Odoriferaes, 50 parts of Pericarpium Citri Reticulataes, 30 parts of Fructus Aurantii Immaturuss, 30 parts of Massa Medicata Fermentata, 40 parts in Poria, 30 parts in Fructus Hordei Germinatus, 10 parts of Rhizoma Coptidis, 20 parts of Radix Scutellariaes, 15 parts of Radix Sophorae Flavescentiss, 15 parts of Cortex Fraxinis, 15 parts of Cortex Dictamni, 30 parts of the Radix Paeoniae Albas, 10 parts of Eupolyphaga Seu Steleophagas, 20 parts of Lignum Sappans, 10 parts of Sanguis Draxonis, 10 parts in catechu, 15 parts of Herba Artemisiae Anomalaes, 100 parts of Radix Astragali, 30 parts of Rhizoma Dioscoreaes, 10 parts in Radix Glycyrrhizae, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Radix Codonopsis, 20 parts of Radix Rehmanniae Preparata, 30 parts of Radix Angelicae Sinensis, 15 parts of Semen Myristicaes, 15 parts of Semen Euryaless, 20 parts of Limonitum, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 20 parts of Flos Loniceraes, 15 parts of Herba Violaes, 15 parts of Fructus Forsythiaes, 20 parts of Herba Taraxaci, 15 parts of Herba Patriniae, 30 parts of Cortex Magnoliae Officinalis, 15 parts of Fructus Amomis, 10 parts of Lignum Aquilariae Resinatum.
Each raw material of above-mentioned weight fraction is mixed, after grinding into fine powder and crossing 1500 mesh sieves, add ethanol and make adhesive, add starch and do filler, be pressed into granule.
The preparation of [embodiment 3] tablet
Take by weighing each raw material by following weight portion: 15 parts of Olibanum (processed), 15 parts of Myrrha (processed)s, 30 parts of Semen Coiciss, 10 parts of Lignum Dalbergiae Odoriferaes, 50 parts of Pericarpium Citri Reticulataes, 30 parts of Fructus Aurantii Immaturuss, 30 parts of Massa Medicata Fermentata, 40 parts in Poria, 30 parts in Fructus Hordei Germinatus, 10 parts of Rhizoma Coptidis, 20 parts of Radix Scutellariaes, 15 parts of Radix Sophorae Flavescentiss, 15 parts of Cortex Fraxinis, 15 parts of Cortex Dictamni, 30 parts of the Radix Paeoniae Albas, 10 parts of Eupolyphaga Seu Steleophagas, 20 parts of Lignum Sappans, 10 parts of Sanguis Draxonis, 10 parts in catechu, 15 parts of Herba Artemisiae Anomalaes, 100 parts of Radix Astragali, 30 parts of Rhizoma Dioscoreaes, 10 parts in Radix Glycyrrhizae, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Radix Codonopsis, 20 parts of Radix Rehmanniae Preparata, 30 parts of Radix Angelicae Sinensis, 15 parts of Semen Myristicaes, 15 parts of Semen Euryaless, 20 parts of Limonitum, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 20 parts of Flos Loniceraes, 15 parts of Herba Violaes, 15 parts of Fructus Forsythiaes, 20 parts of Herba Taraxaci, 15 parts of Herba Patriniae, 30 parts of Cortex Magnoliae Officinalis, 15 parts of Fructus Amomis, 10 parts of Lignum Aquilariae Resinatum.
Each raw material of above-mentioned weight portion is mixed, after grinding into fine powder and crossing 800~1200 order dusting covers, make tablet promptly.
The preparation of [embodiment 4] pill
Take by weighing each raw material by following weight portion: 15 parts of Olibanum (processed), 15 parts of Myrrha (processed)s, 30 parts of Semen Coiciss, 10 parts of Lignum Dalbergiae Odoriferaes, 50 parts of Pericarpium Citri Reticulataes, 30 parts of Fructus Aurantii Immaturuss, 30 parts of Massa Medicata Fermentata, 40 parts in Poria, 30 parts in Fructus Hordei Germinatus, 10 parts of Rhizoma Coptidis, 20 parts of Radix Scutellariaes, 15 parts of Radix Sophorae Flavescentiss, 15 parts of Cortex Fraxinis, 15 parts of Cortex Dictamni, 30 parts of the Radix Paeoniae Albas, 10 parts of Eupolyphaga Seu Steleophagas, 20 parts of Lignum Sappans, 10 parts of Sanguis Draxonis, 10 parts in catechu, 15 parts of Herba Artemisiae Anomalaes, 100 parts of Radix Astragali, 30 parts of Rhizoma Dioscoreaes, 10 parts in Radix Glycyrrhizae, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Radix Codonopsis, 20 parts of Radix Rehmanniae Preparata, 30 parts of Radix Angelicae Sinensis, 15 parts of Semen Myristicaes, 15 parts of Semen Euryaless, 20 parts of Limonitum, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 20 parts of Flos Loniceraes, 15 parts of Herba Violaes, 15 parts of Fructus Forsythiaes, 20 parts of Herba Taraxaci, 15 parts of Herba Patriniae, 30 parts of Cortex Magnoliae Officinalis, 15 parts of Fructus Amomis, 10 parts of Lignum Aquilariae Resinatum.
Each raw material of above-mentioned weight is mixed, grind into cross 600~1000 mesh sieves behind the fine powder after, make pill promptly.
The preparation of [embodiment 5] oral liquid
Take by weighing each raw material by following weight portion: 15 parts of Olibanum (processed), 15 parts of Myrrha (processed)s, 30 parts of Semen Coiciss, 10 parts of Lignum Dalbergiae Odoriferaes, 50 parts of Pericarpium Citri Reticulataes, 30 parts of Fructus Aurantii Immaturuss, 30 parts of Massa Medicata Fermentata, 40 parts in Poria, 30 parts in Fructus Hordei Germinatus, 10 parts of Rhizoma Coptidis, 20 parts of Radix Scutellariaes, 15 parts of Radix Sophorae Flavescentiss, 15 parts of Cortex Fraxinis, 15 parts of Cortex Dictamni, 30 parts of the Radix Paeoniae Albas, 10 parts of Eupolyphaga Seu Steleophagas, 20 parts of Lignum Sappans, 10 parts of Sanguis Draxonis, 10 parts in catechu, 15 parts of Herba Artemisiae Anomalaes, 100 parts of Radix Astragali, 30 parts of Rhizoma Dioscoreaes, 10 parts in Radix Glycyrrhizae, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Radix Codonopsis, 20 parts of Radix Rehmanniae Preparata, 30 parts of Radix Angelicae Sinensis, 15 parts of Semen Myristicaes, 15 parts of Semen Euryaless, 20 parts of Limonitum, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 20 parts of Flos Loniceraes, 15 parts of Herba Violaes, 15 parts of Fructus Forsythiaes, 20 parts of Herba Taraxaci, 15 parts of Herba Patriniae, 30 parts of Cortex Magnoliae Officinalis, 15 parts of Fructus Amomis, 10 parts of Lignum Aquilariae Resinatum.
Each raw material of above-mentioned weight is mixed, after three decoctions, three filtrates are mixed, filter, be concentrated into rule
Fixed concentration, put cold, the stock solution embedding, irradiation sterilization, after the check, packed products is made oral liquid promptly.
The clinical observation on the therapeutic effect experiment of [experimental example] traditional Chinese medicine composition for treating duodenal ulcer patients of the present invention
One, the physical data of experimental subject: adopt Chinese medicine composition of the present invention to treat 55 routine patients altogether, wherein male 34 examples, women 21 examples; The oldest person 78 years old, the age reckling has only 16 years old.
Two, Therapeutic Method:
Usage and dosage: adopt the prepared medicament of the embodiment of the invention, its usage and consumption are as follows: 1) capsule: obey 2~5 every day three times at every turn, and every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2~4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.5) powder: every day three times, each 2~4 grams, warm water takes.
The course of treatment: one month is a course of treatment, treats for 6 courses of treatment altogether.
Three, therapeutic evaluation standard
Cure: sign and symptom are improved fully, and diet, stool are normal, and weight increase is in high spirits.
Produce effects: sign and symptom are significantly improved, diet, the stool normal substantially, weight increase, spirit fine.
Effectively: sign and symptom change, and diet, stool are improved, and random thoughts have discomfort slightly, but can accept.
Invalid: sign does not have change, symptom such as preceding.
Four, model case:
1, Zhao, man, 38 years old, doctor.
Beginning epigastrium pain before more than 20 year, obvious during with hunger, the companion returns acid, belch, and stool blood (+) is checked to examine to be duodenal ulcer sometimes.Do not have produce effects through western medicines in treatment, how in the time when autumn turns into winter and at the end of spring and the beginning of summer annual outbreak, or shows effect during improper diet for several times.The normal upper abdomen severe pain suddenly of recent patient, and emit to shoulder, pain increases the weight of during breathing, separates pitch sample stool, and unable, the companion vomits, and vomitus is a food, pale complexion during outbreak, dripping sweat.
Took Chinese medicine composition of the present invention 5, upper abdomen severe pain obviously alleviates.Continue and obeyed Chinese medicine composition of the present invention 15, pain is further alleviated, and vomiting alleviates, and stool blood ends.Continue and obeyed Chinese medicine composition of the present invention 2 months, the accidental work of pain, degree alleviates, and vomiting ends, and spirit is gradually shaken.It is surplus March to obey Chinese medicine composition of the present invention again, and all diseases are removed entirely, follows up a case by regular visits to so far not recurrence.
2, Liu, man, 46 years old, manager.
The diet of making business before 3 years is irregular, hungry after a full meal, epigastrium dull pain increases the weight of after the meal, with abdominal distention, have the hiccups, inappetence, lose weight, defecate shapeless, symptom such as gloomy and dyspepsia of complexion.It is ineffective to go over various big hospital.Ultrasonic and gastroscope is diagnosed: duodenal bulbar ulcer.
Took Chinese medicine composition of the present invention 15, upper abdominal pain, abdominal distention are alleviated.Continue and obeyed Chinese medicine composition of the present invention 20, symptom obviously alleviates, and appetite strengthens, 2 jin of weight increase.Continue and obeyed Chinese medicine composition of the present invention 3 months, main suit's transference cure, stool is normal, is after treatment.It is surplus January to obey Chinese medicine composition of the present invention again, and weight increase is had rosy cheeks for 10 jin, cures so far not recurrence.
3, Lee so-and-so, man, 35 years old, cadre.
The intermittent dull pain of patient's epigastrium 1 year increased the weight of one month, intermittent dull pain under beginning xiphoid-process the first half of the year, with nauseating belch acid regurgitation water, pain is the acupuncture sample, on an empty stomach for very, the alleviation of feed back, the pain relieved by pressing desire for hot drinks, the poor appetite loose stool, the time be with black.In local certain hospital, barium meal is diagnosed " duodenal bulbar ulcer ", hospitalization before half a year.Nearly two weeks comes, and the state of an illness is control not, increases the weight of on the contrary.Patient's bitter taste poor appetite, malaise, it is relatively poor to sleep, and expression is painful, tongue body obesity, white and greasy fur, deep-thready pulse.
Took Chinese medicine composition of the present invention 15, state of an illness basic controlling.Continue and obeyed Chinese medicine composition of the present invention 20, symptom is further alleviated, and diet increases, and spirit takes a turn for the better, and gastroscope check duodenal bulbar ulcer face reduces.Continue and obeyed Chinese medicine composition of the present invention 1 month, pain disappears substantially, and it is gradually normal to defecate, and spirit continues to take a turn for the better, and gastroscope check duodenal bulbar ulcer face continues to reduce.It is surplus March to obey Chinese medicine composition of the present invention again, and symptom all disappears, and gastroscope check duodenal bulbar ulcer has formed mucosa and concentrated (healing), looks like the normal person.The patient fully recovers, and phone is followed up a case by regular visits to, and does not see recurrence.
4, Chen, woman, 36 years old, teacher.
Do 1 year during epigastrium pain, increased the weight of 3 months.The patient sends out epigastrium pain over 1 year the time, increased the weight of in nearly three months, and whenever in aggravation about 2 hours after meal, general sometimes acid regurgitation water, bitter taste xerostomia, constipation with dry stool, gastroscope report: duodenal bulbar ulcer, HP:+++.Red tongue, yellow and thin fur, wiry and frequent pulse.
Took Chinese medicine composition of the present invention 7, the epigastrium pain relief is more than half, and acid regurgitation water reduces.Continue and obeyed Chinese medicine composition of the present invention 20, symptom is further alleviated, and diet increases, and spirit takes a turn for the better, and gastroscope check duodenal bulbar ulcer face reduces HP:++.Continue and obeyed Chinese medicine composition of the present invention 1 month, epigastrium pain disappears substantially, does not have general acid regurgitation water, the xerostomia sx, and no bitter taste, it is more smooth to defecate.It is surplus February to obey Chinese medicine composition of the present invention again, transference cure, and the check gastroscope: duodenal bulbar ulcer heals, and HP:-followed up a case by regular visits to 2 years, not recurrence.
5, Shen, man, 48 years old, workman.
The main suit: the duodenal ulcer postoperative, gastral cavilty distending pain 10 years is surplus.History of present illness: the patient before 10 years because of the capable gastric resection of duodenal ulcer, postoperative gastral cavilty place stationarity distending pain endlessly, poor appetite, the xerostomia hardship is seen stomach anastomotic stoma inflammation, yellow and greasy fur, stringy and rolling pulse under the constipation with dry stool, gastroscope.
Took Chinese medicine composition of the present invention 15, flatulence subtracts, and still has a pain, and receives not increase, and stool owes smooth.Continue and obeyed Chinese medicine composition of the present invention 1 month, distending pain, xerostomia hardship all subtract, and stool day separates.Obeyed Chinese medicine composition of the present invention again 2 months, symptom disappears substantially, does not have discomfort, receives to increase, and is just smooth, after treatment.Obey Chinese medicine composition of the present invention 1 month again and consolidate, patient's recovery from illness follows up a case by regular visits to that the patient is normal so far.
6, stone, man, 30 years old, driver.
Patient's readme discontinuity epigastrium dull pain 3 years is surplus, whenever in autumn and winter season the state of an illness increase the weight of.Existing epigastrium dull pain, pain very must be eaten alleviation of pain when hungry, the sore spot desire for warm and being pressed, the abdominal distention belch, body is tired weak, the hands and feet being not warm, shallow complexion, emaciated physique, stool is the pitch shape, and every day 2~4 times, pale tongue is dark, white and thin fur, corpulent tongue is big, and indentation is seen on the limit, deep-thready pulse.Gastroscopy prompting: duodenal bulbar ulcer.
Took Chinese medicine composition of the present invention 15, epigastrium pain, abdominal distention obviously alleviate, and tarry stool disappears, but stool is still half congealed thin, day row 2~3 times.Continue and obeyed Chinese medicine composition of the present invention 1 month, transference cures such as epigastrium pain, abdominal distention, belch, stool is normal, is after treatment.Obeyed Chinese medicine composition of the present invention again 2 months, spirit, diet is all good, and two is just normal, and no significant discomfort sense point out through gastroscopy: duodenal bulbar ulcer heals, and does not follow up a case by regular visits to after 1 year and recurs.
7, Zheng, man, 37 years old, technician.
It is tired that the patient is set forth in cause overwork in 4 years certainly, and eating and drinking without temperance is hungry full inappropriate in addition, likes raw and cold, greasy, the pungent product of food again, causes epigastrium pain, and health is become thin gradually.Though take the treatment of multiple Chinese and western drugs for a long time, heavy when light during the state of an illness, outbreak is repeatedly cured eventually.Before 1 week again because of drink ice beer cause the stomachache increase the weight of, point out through gastroscopy: duodenal bulbar ulcer.Disease is seen when examining: the epigastrium twinge, and sore spot is fixing not to be moved, abdominal distention, poor appetite, belch, body is tired weak, and big loose stool is thin, day row 3~4 times, pale tongue is dark, and fat big, ecchymosis is seen on the limit, and tongue is greasy in vain, deep and hesitant pulse.
Took Chinese medicine composition of the present invention 15, remission.Continue and obeyed Chinese medicine composition of the present invention 20, epigastrium pain is not done, and abdominal distention, belch symptom subtract greatly, and health is more preceding strong, receives and eats more preceding increase, and still big loose stool is thin, day row 2~3 times.The clothes Chinese medicine composition of the present invention 20 days that continues, symptom disappears substantially, and spirit, muscle power, diet, stool are all normal, and it is ruddy that complexion is tending towards, and the more preceding increase of body weight, but raw and cold, the pungent product of taking food are whenever promptly felt in the stomach and being had a dull ache.Obeyed Chinese medicine composition of the present invention again 3 months, spirit, diet is all good, do not have special discomfort, and through the check gastroscope: the duodenal bulbar ulcer healing, disease obtains recovery from illness, follows up a case by regular visits to after half a year, does not feel special discomfort.
8, often so-and-so, man, 34 years old, workman.
The main suit: epigastrium pain 1 month, increased the weight of half.Medical history: the patient once felt sick suddenly before August, acid regurgitation, abdominal distention, and epigastrium paroxysmal is had a pain, and the food back is alleviated, and today is because of overexerting, back gastral cavity portion severe pain, hyperpyrexia and seeking medical advice.The patient has 4 years gastropathy histories.Gastroscopy prompting: duodenal ulcer.Body of the tongue is light red, and greasy fur is yellow does stringy and tense pulse.
Took Chinese medicine composition of the present invention 15, back gastral cavity portion severe pain subtracts greatly.Continue and obeyed Chinese medicine composition of the present invention 20, the epigastrium paroxysmal pain is not done, and abdominal distention subtracts greatly, continues and obeys Chinese medicine composition of the present invention 20, and abdominal distention continues to alleviate, and acid regurgitation and vomiting stop.Obeyed Chinese medicine composition of the present invention again 2 months, through checking gastroscope: the duodenal bulbar ulcer healing, the patient is healed, does not follow up a case by regular visits to recurrence after 2 years.
Five, therapeutic outcome:
In the 55 routine cases of being accepted for medical treatment,, wherein cure 27 examples through treatment in 6 months, produce effects 19 examples, effective 7 examples, invalid 2 examples, total effective rate reaches 96 %.The result shows that Chinese medicine composition of the present invention has extremely significant curative effect to the treatment duodenal ulcer patients.

Claims (4)

1. Chinese medicine composition for the treatment of duodenal ulcer, it is characterized in that: the weight portion of each crude drug is:
15 parts of Olibanum (processed), 15 parts of Myrrha (processed)s, 30 parts of Semen Coiciss, 10 parts of Lignum Dalbergiae Odoriferaes, 50 parts of Pericarpium Citri Reticulataes, 30 parts of Fructus Aurantii Immaturuss, 30 parts of Massa Medicata Fermentata, 40 parts in Poria, 30 parts in Fructus Hordei Germinatus, 10 parts of Rhizoma Coptidis, 20 parts of Radix Scutellariaes, 15 parts of Radix Sophorae Flavescentiss, 15 parts of Cortex Fraxinis, 15 parts of Cortex Dictamni, 30 parts of the Radix Paeoniae Albas, 10 parts of Eupolyphaga Seu Steleophagas, 20 parts of Lignum Sappans, 10 parts of Sanguis Draxonis, 10 parts in catechu, 15 parts of Herba Artemisiae Anomalaes, 100 parts of Radix Astragali, 30 parts of Rhizoma Dioscoreaes, 10 parts in Radix Glycyrrhizae, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Radix Codonopsis, 20 parts of Radix Rehmanniae Preparata, 30 parts of Radix Angelicae Sinensis, 15 parts of Semen Myristicaes, 15 parts of Semen Euryaless, 20 parts of Limonitum, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 20 parts of Flos Loniceraes, 15 parts of Herba Violaes, 15 parts of Fructus Forsythiaes, 20 parts of Herba Taraxaci, 15 parts of Herba Patriniae, 30 parts of Cortex Magnoliae Officinalis, 15 parts of Fructus Amomis, 10 parts of Lignum Aquilariae Resinatum.
2. according to the described Chinese medicine composition of claim 1, it is characterized in that: the method for Chinese medicinal according to routine is prepared into any oral formulations commonly used.
3. according to the described Chinese medicine composition of claim 2, it is characterized in that: described oral formulations is pill, capsule, tablet, powder, granule or oral liquid.
4. the application of any described Chinese medicine composition of claim 1~3 in preparation treatment duodenal ulcer medicine.
CN2010101408594A 2010-04-07 2010-04-07 Chinese medicine composite for treating duodenal ulcer and preparation method thereof Expired - Fee Related CN101766774B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2010101408594A CN101766774B (en) 2010-04-07 2010-04-07 Chinese medicine composite for treating duodenal ulcer and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2010101408594A CN101766774B (en) 2010-04-07 2010-04-07 Chinese medicine composite for treating duodenal ulcer and preparation method thereof

Publications (2)

Publication Number Publication Date
CN101766774A CN101766774A (en) 2010-07-07
CN101766774B true CN101766774B (en) 2011-06-15

Family

ID=42499976

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010101408594A Expired - Fee Related CN101766774B (en) 2010-04-07 2010-04-07 Chinese medicine composite for treating duodenal ulcer and preparation method thereof

Country Status (1)

Country Link
CN (1) CN101766774B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102416158B (en) * 2011-12-10 2013-04-03 许从玉 Chinese medicinal composition for preventing or treating duodenal ulcer

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101991756B (en) * 2010-10-27 2012-05-23 通城县人民医院 Use of longstamen onion bulb as medicament for preventing intestinal adhesion
CN102178811B (en) * 2011-04-28 2012-11-21 上海市中医医院 Medicament for treating skin ulcer and preparation method thereof
CN102228597B (en) * 2011-06-13 2013-02-27 武汉理工大学 Medicament for treating oral ulcer and preparation method
CN102727816B (en) * 2012-06-19 2013-10-30 刘文生 Traditional Chinese medicine composition used for treating ulcerative colitis
CN102895280A (en) * 2012-09-17 2013-01-30 刘增智 Cancer cell inhibiting medicament
CN103041365B (en) * 2013-01-06 2014-08-27 刘艳芳 Medicament for treating gastric ulcer
CN103212008B (en) * 2013-03-27 2014-09-24 林艳 Traditional Chinese medicine composition used for treating stomach carbuncle
CN103251682A (en) * 2013-05-31 2013-08-21 颜文超 Medical wine for treating various stomachaches
CN103386024B (en) * 2013-06-19 2014-10-22 孙伟 Traditional Chinese medicine preparation for treating pancreas cancer and preparation method thereof
CN103656140A (en) * 2013-12-07 2014-03-26 库里米拉·赛力克 Traditional Kazakh medicinal composition for treating duodenal ulcer and preparation method of composition
CN104758780A (en) * 2015-03-17 2015-07-08 覃慧璇 Traditional Chinese medicine composition for treating gastroduodenal ulcer in the type of dyspepsia in gastral cavity
CN104888095A (en) * 2015-05-04 2015-09-09 淄博齐鼎立专利信息咨询有限公司 Traditional Chinese medicinal composition for treating duodenal ulcer
CN105833170A (en) * 2016-03-30 2016-08-10 杨海林 Medicine composition for clinically nursing peptic ulcer

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101537156A (en) * 2009-01-22 2009-09-23 曹莹莹 Chinese herbal medicine composite capable of curing stomach illness and duodenal ulcer disease
CN101642539A (en) * 2009-09-01 2010-02-10 廖国新 Medicine composition for treating peptic ulcer and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101537156A (en) * 2009-01-22 2009-09-23 曹莹莹 Chinese herbal medicine composite capable of curing stomach illness and duodenal ulcer disease
CN101642539A (en) * 2009-09-01 2010-02-10 廖国新 Medicine composition for treating peptic ulcer and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
苏荣立等.中药治疗胃及十二指肠溃疡62例.《辽宁中医学院学报》.2003,第5卷(第3期),247. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102416158B (en) * 2011-12-10 2013-04-03 许从玉 Chinese medicinal composition for preventing or treating duodenal ulcer

Also Published As

Publication number Publication date
CN101766774A (en) 2010-07-07

Similar Documents

Publication Publication Date Title
CN101766774B (en) Chinese medicine composite for treating duodenal ulcer and preparation method thereof
CN101773633B (en) Chinese medicine composition for treating gastric ulcer
CN101766782B (en) Chinese medicine composite for treating chronic gastritis and preparation method thereof
CN101785844B (en) Traditional Chinese medicine combination and preparation method thereof for dysentery treatment
CN101766790B (en) Chinese medicine composite for treating chronic atrophic gastritis and preparation method thereof
CN101961464B (en) Chinese medicinal composition for treating jaundice and preparation method thereof
CN101757542B (en) Traditional Chinese medicine composition for treating colonitis and preparation method
CN101766802B (en) Chinese medicine composite for treatment of acute gastroenteritis and preparation method thereof
CN101804173B (en) Traditional Chinese medicine composition for treating dyspepsia and preparation method thereof
CN101693102A (en) Traditional Chinese medicine compound for treating diseases of incoordination between the spleen and the stomach and abdominal fullness and distention and preparation method thereof
CN101757509B (en) Traditional Chinese medicine composition for treating icterohepatitis and preparation method thereof
CN101785835A (en) Traditional Chinese medicine combination and preparation method thereof for chronic enteritis treatment
CN101766803B (en) Chinese medicine composite for treating epigastric pain and preparation method thereof
CN101804172A (en) Traditional Chinese medicine composition for treating anorexia and preparation method thereof
CN101773634A (en) Chinese medicine composition for treating abdominal distention and fullness and preparation method thereof
CN101829294B (en) Traditional Chinese medicine composite for treating pyretic pulmonary disease and preparation method thereof
CN101961480A (en) Traditional Chinese medicinal composition for treating hematochezia and preparation method thereof
CN101837112B (en) Chinese medicinal composition for curing irregular menstrual period and preparation method thereof
CN101816772B (en) Chinese medicament for treating globus hystericuss and preparation method thereof
CN101773647B (en) Chinese medicine composition for treating duodenal carcinoma and preparation method thereof
CN101757602B (en) Traditional Chinese medicine composition for treating cardiac carcinoma and preparation method thereof
CN101874894B (en) Chinese medicinal composition for treating vomit and preparation method thereof
CN101757500A (en) Traditional Chinese medicine composition for treating typhitis and preparation method thereof
CN102949685A (en) Traditional Chinese medicine composition for treating chronic gastritis
CN101810836A (en) Chinese medicinal composition for treating belching and preparation method thereof

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20110615

Termination date: 20130407