CN101756216B - Yeast nutritious food and preparation method thereof - Google Patents
Yeast nutritious food and preparation method thereof Download PDFInfo
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- CN101756216B CN101756216B CN2008101866665A CN200810186666A CN101756216B CN 101756216 B CN101756216 B CN 101756216B CN 2008101866665 A CN2008101866665 A CN 2008101866665A CN 200810186666 A CN200810186666 A CN 200810186666A CN 101756216 B CN101756216 B CN 101756216B
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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Abstract
The invention discloses yeast nutritious food and a preparation method thereof. The yeast nutritious food adopts yeasts as a main raw material, comprises milk powder, maltodextrin , lactose, non-dairy creamer, calcium carbonate, starch, white granulated sugar, flavoring agent and essence and also comprises folic acid, B vitamins, vitamin A, vitamin C, selenium-rich yeast, zinc-rich yeast, chromium-rich yeast, iron-rich yeast, other trace elements-rich yeast, calcium carbonate, dehydrated onion slice, microcrystalline cellulose, starch, cocoa powder, fruit and vegetable powder, sesame, milk tea powder, soy-bean milk powder and oat flakes. The invention adopts multiple raw auxiliary materials, and can be used for preparing yeast nutritious food in such forms as powder, flakes and tablets through various preparation processes, so as to develop nutritious food with tastes applicable to various groups. Moreover, multiple raw auxiliary materials can be added. Compared with the existing yeast nutritious food, the yeast nutritious food of the invention has the function of significantly improving the immunity of the user.
Description
Technical field
The present invention relates to a kind of yeast nutrition food and preparation method thereof.
Background technology
The yeast thalline is unicellular eukaryotic microorganisms, belongs to Homonemeae food with mushroom, auricularia auriculajudae etc., wherein contains multiple nutritional components such as more rich protein and vitamin, carbohydrate, fat, mineral matter, nucleic acid.Contain 18 seed amino acids in the saccharomycete; And the amino acid that contains needed by human; The less lysine of content in corn gluten protein particularly; Content is higher in the yeast thalline, and amino acid whose ratio is near the comparatively ideal amino acid composition value of FAO (Food and Agriculture Organization of the United Nation) (FAO) recommendation, so its nutritive value is higher.Along with the quick growth of world population, deprivation of food is remarkable day by day, and especially shortage appears in protein food.The production of traditional plant animal protein food receives agricultural technology, and the restriction of all kinds of envirment factors, increasess slowly, and is difficult to satisfy the demand of human protein's consumption.The frontier of obtaining protein has been opened up in the appearance of this single cell protein of yeast.
In addition, contain abundant vitamin, mineral matter and polysaccharide in the saccharomycete, can more balanced nutrition be provided for human body.And fat content is very low in the yeast, does not contain cholesterol, is healthy food low in calories, high nutrition.
Because yeast contains so abundant nutrition, thereby make that preparing nutritious and healthy food with yeast becomes possibility.At present, in the prior art be that the nutraceutical of primary raw material only comprises a few raw material with the yeast, yeast then only adopts dusty yeast, and preparation technology is single.Patent " a kind of nutritious yeast foodstuff and preparation method thereof " (200510015005.2) for example; The nutritious yeast foodstuff that it disclosed only comprises nutrient yeast powder, whole milk powder, beta-schardinger dextrin-, sweetener, vegetable fat powder and other additives, only adopts tablet manufacturing technology and prepare this food.Therefore, prepare comprise multiple nutritional components, have different dosage form, yeast nutrition food that mouthfeel is fit to various crowds becomes the direction that people pay close attention to.
Summary of the invention
In order to solve in the prior art, problem such as yeast nutrition food formula limitation, preparation technology are single the invention provides a kind of yeast nutrition food and preparation method thereof.
One aspect of the present invention; A kind of yeast nutrition food is provided, and this yeast nutrition food is primary raw material with the yeast; Comprise milk powder, maltodextrin, lactose, vegetable fat powder, calcium carbonate, starch, white granulated sugar and flavouring, essence; It is characterized in that said yeast nutrition food also comprises B family vitamin and the yeast that is rich in trace element, said component has following weight portion:
Yeast 5-97,
Milk powder 1-20,
Vegetable fat powder 1-50,
Calcium carbonate 0.1-50,
Starch 1-50,
Maltodextrin 0-50,
Lactose 0-50,
White granulated sugar 0-70,
Folic acid 0-1,
Cobastab
120-1
Cobastab
10-10,
Cobastab
20-10,
Vitamin A 0-10,
Vitamin C 0-20,
Se-enriched yeast 0-10,
Zinc-rich saccharomyces cerevisiae 0-40,
Ferrum-rich saccharomyces cerevisiae 0-10,
Cr-enriched yeast 0-10,
Microcrystalline cellulose 0-20.
According to yeast nutrition food of the present invention, wherein, further comprise having following components in part by weight:
White granulated sugar 1-70,
Folic acid 0.00001-1,
Cobastab
120.00001-1,
Cobastab
10.0001-10,
Cobastab
20.0001-10,
Vitamin A 0.0001-10,
Vitamin C 0.0001-20,
Se-enriched yeast 0.0001-10,
Zinc-rich saccharomyces cerevisiae 1-40,
Ferrum-rich saccharomyces cerevisiae 1-10,
Cr-enriched yeast 0.0001-10,
Microcrystalline cellulose 1-20.
According to yeast nutrition food of the present invention, wherein, also comprise the component of following weight portion:
Air-dried onion in slice 1-10,
Cocoa power 1-20,
Fruits and vegetables powder 1-20,
Sesame 1-50,
Milk tea powder 1-20,
Soymilk powder 1-20,
Oatmeal 1-20.
According to yeast nutrition food of the present invention, wherein, the primary raw material yeast can be dusty yeast or yeast milk.
According to yeast nutrition food of the present invention, wherein, this yeast nutrition food also comprises ferrum-rich saccharomyces cerevisiae and Cr-enriched yeast.
According to yeast nutrition food of the present invention, wherein, ferrum-rich saccharomyces cerevisiae can be by being ferrous gluconate, amino acid chelated iron, ferrous sulfate, ferrous fumarate, ferrous lactate or their mixture replacements arbitrarily; Zinc-rich saccharomyces cerevisiae can be by zinc sulfate, zinc gluconate, zinc lactate, zinc citrate, zinc-amino acid chelate or their mixture replacements arbitrarily; Se-enriched yeast can be replaced by sodium selenite; Flavouring is citric acid, malic acid.
In a specific embodiment of yeast nutrition food of the present invention; Wherein, yeast nutrition food comprises the component of following weight portion: yeast 5-97, milk powder 1-20, vegetable fat powder 1-50, calcium carbonate 0.1-50, starch 1-50, vitamin C 0.1-0.3, white granulated sugar 20-70, cocoa power 1-20.
In a specific embodiment of yeast nutrition food of the present invention, wherein, yeast nutrition food comprises the component of following weight portion: yeast 5-97, milk powder 1-20, vegetable fat powder 1-50, calcium carbonate 0.1-50, starch 1-50, microcrystalline cellulose 1-20.
In a specific embodiment of yeast nutrition food of the present invention; Wherein, yeast nutrition food comprises the component of following weight portion: yeast 5-95, milk powder 1-20, vegetable fat powder 1-50, calcium carbonate 0.1-50, starch 1-50, sesame 1-20, white granulated sugar 1-20, maltodextrin 10-50.
In a specific embodiment of yeast nutrition food of the present invention; Wherein, yeast nutrition food comprises the component of following weight portion: yeast 5-95, milk powder 1-20, vegetable fat powder 1-50, calcium carbonate 0.1-50, starch 1-50, white granulated sugar 20-70, fruits and vegetables powder 1-20, flavouring 1-20.
In a specific embodiment of yeast nutrition food of the present invention, wherein, yeast nutrition food comprises the component of following weight portion: yeast 5-95, milk powder 1-20, vegetable fat powder 1-50, calcium carbonate 0.1-50, starch 1-50, air-dried onion in slice 1-10.
In a specific embodiment of yeast nutrition food of the present invention; Wherein, yeast nutrition food comprises the component of following weight portion: yeast 5-95, milk powder 1-20, vegetable fat powder 1-50, calcium carbonate 0.1-50, starch 1-50, folic acid 0.05-0.1, cobalamin 0.0002, vitamin A 0.1-0.3, vitamin C 0.1-0.3, ferrum-rich saccharomyces cerevisiae 1-10.
According to yeast nutrition food of the present invention, wherein, the B family vitamin is to be selected from the group that vitamin B1, vitamin B2, cobalamin, pantothenic acid, nicotinic acid form any.
In a specific embodiment of yeast nutrition food of the present invention; Wherein, yeast nutrition food comprises the component of following weight portion: yeast 5-95, milk powder 1-20, vegetable fat powder 1-50, calcium carbonate 0.1-50, starch 1-50, Zinc-rich saccharomyces cerevisiae 1-10, Se-enriched yeast 1-10, Cr-enriched yeast 1-10, ferrum-rich saccharomyces cerevisiae 1-10.
In a specific embodiment of yeast nutrition food of the present invention; Wherein, Yeast nutrition food comprises the component of following weight portion: yeast 5-95, milk powder 1-20, vegetable fat powder 1-50, calcium carbonate 0.1-50, starch 1-50, milk tea powder, soymilk powder and oatmeal totally 60.
According to yeast nutrition food of the present invention, be fit to any formulation in powdery, snowflake shape, the tablet.
Another aspect of the present invention provides the preparation method according to yeast nutrition food of the present invention.
According to the method that is used to prepare yeast nutrition food of the present invention, comprising: yeast and other raw materials are mixed and add water stir according to prescription, then spray-drying and packing to obtain the yeast nutrition food of powdery.
According to the method that is used to prepare yeast nutrition food of the present invention; Comprise: yeast is added water stir, carry out drying with roller drier then, wherein baking temperature is controlled at 180 ℃; Collect and use screen filtration after the drying; Add said other supplementary materials again and mix, pack at last, thereby obtain the yeast nutrition food of snowflake shape.
According to the method that is used to prepare yeast nutrition food of the present invention, comprising: yeast and other raw materials are mixed according to prescription, process tablet through steps such as granulation, drying, compressing tablets then, obtain the yeast nutrition food of tablet at last through packing.
Compared with prior art; Yeast nutrition food of the present invention is in prior art the existing raw material; Multiple materials such as vitamin A, B family vitamin, vitamin C, ferrum-rich saccharomyces cerevisiae, Zinc-rich saccharomyces cerevisiae, Se-enriched yeast, Cr-enriched yeast have also been added; Improved the trophism of Yeast food, satisfied the demand of eater simultaneously the multiple nutrients material; In addition, the present invention adopts kinds of processes to carry out the preparation of yeast nutrition food, can obtain the yeast nutrition food of different dosage forms such as powdery, snowflake shape, tablet, develops mouthfeel and is fit to the nutraceutical that different crowd is taken.
The specific embodiment
Hereinafter will be enumerated the specific embodiment of yeast nutrition food of the present invention.Those skilled in the art should understand, and cited specific embodiment only is for illustrative purpose, but not in order to limit scope of the present invention.
Embodiment 1
In embodiments of the invention 1, yeast nutrition food comprises the component of following weight portion: yeast 90, milk powder 18, vegetable fat powder 45, calcium carbonate 5.3, starch 50, Se-enriched yeast 2, Zinc-rich saccharomyces cerevisiae 2, Cr-enriched yeast 2, folic acid 0.1, Cobastab
10.1, Cobastab
20.1, Cobastab
120.001, ferrum-rich saccharomyces cerevisiae 2.
Embodiment 2
In embodiments of the invention 2, yeast nutrition food comprises the component of following weight portion: yeast 10, milk powder 10, vegetable fat powder 10, calcium carbonate 10, starch 17.6, Se-enriched yeast 8, Zinc-rich saccharomyces cerevisiae 8, Cr-enriched yeast 8, ferrum-rich saccharomyces cerevisiae 8, Cobastab
10.002, Cobastab
20.002, Cobastab
120.00005, white granulated sugar 20, cocoa power 10, maltodextrin 10.
Embodiment 3
In embodiments of the invention 3, yeast nutrition food comprises the component of following weight portion: yeast 50, milk powder 5, vegetable fat powder 20, calcium carbonate 40, starch 30, Se-enriched yeast 5, Zinc-rich saccharomyces cerevisiae 10, Cr-enriched yeast 5, folic acid 0.05, Cobastab
15, Cobastab
25, Cobastab
120.001, white granulated sugar 4.95.
Yeast nutrition food of the present invention is fit to comprise the different dosage form of powdery, snowflake shape, tablet, thereby to different dosage forms, and the method that the present invention is used to prepare yeast nutrition food can comprise following three kinds:
Be used to prepare the method for dusty yeast nutraceutical, comprise: yeast and other raw materials are mixed and add water stir according to prescription, then spray-drying and packing to obtain the dusty yeast nutraceutical.
Be used to prepare the method for snowflake shape yeast nutrition food; Comprise: yeast is added water stir, carry out drying with roller drier then, wherein baking temperature is controlled at 180 ℃; Collect and use screen filtration after the drying; Add said other supplementary materials again and mix, pack at last, thereby obtain snowflake shape yeast nutrition food.
Be used to prepare the method for tablet yeast nutrition food, comprise: yeast and other raw materials are mixed according to prescription, process tablet through steps such as granulation, drying, compressing tablets then, obtain tablet yeast nutrition food through packing at last.The preparation of tablet can adopt wet granulation, one-step-granulating method to granulate or direct compression process.
Prove that through functional experiment the present invention has the function of significant enhance immunity power, and its effect increases than like product, concrete experimental data is following:
1 material and method
1.1 tried thing: the yeast nutrition food (hereinafter to be referred as yeast nutrition food B, filling a prescription is: nutrient yeast powder 18g, whole milk powder 44g, vegetable fat powder 15g, sucrose 9g, fructose 7.5g, beta-schardinger dextrin-2g cocoa power 1.05g coffee powder 0.05g, cocoa powder essence 3.4g) of the yeast nutrition food embodiment 1,2,3 (hereinafter to be referred as yeast nutrition food A1, A2, A3) of this patent invention, patent " a kind of nutritious yeast foodstuff and preparation method thereof " (200510015005.2) invention.Adult's recommended amounts is 10g/d.By adult 60kg batheroom scale, i.e. 0.17g/kg.bw.Be mixed with different solutions by desired concn and irritate stomach.
1.2 experimental animal: cleaning level BALB/c mouse, male, 200,18-22g (Animal Experimental Study center, Hubei Province)
1.3 grouping, administration: mouse is divided into 5 groups at random: normal control group, the A1 that adds yeast nutrition food, A2, A3 organize, add yeast nutrition food B group.Organize and add yeast nutrition food B group by 30 times of human intaking amounts (5.0g/kg.bw) filling stomach, irritate the long-pending 0.2ml/10g.bw of being of body of stomach for three that add yeast nutrition food A1-A3.
1.4 key instrument and reagent: 5mm diameter card punch, microscope, Microhemagglutination breadboard, centrifuge, ELIASA, 96 well culture plates, 5%CO2 incubator, injection prepared Chinese ink, concanavalin A (ConA), MTT, DNFB, physiological saline, chicken red blood cell, Giemsa dye liquor, YAC-1 cell, Hanks liquid, RPMI1640 complete culture solution, lithium lactate, p-Iodonitrotetrazolium violet (INT), azophenlyene dimethyl ester sulfate (PMS), NAD, Tris-HCl buffer solution
1.5 experimental technique
1.5.1 carbon is cleaned up experiment and internal organs/weight ratio pH-value determination pH: test latter stage; After mouse is weighed, inject the india ink (100mg/kg) of dilution from mouse tail vein, inject behind the prepared Chinese ink 2,10min by body weight; Get blood 20 μ l from the angular vein clump respectively, existing side by side, soon it is added to 2ml0.1%Na
2CO
3In the solution.With 721 spectrophotometers at 600nm place photometry density value (OD), with Na
2CO
3Solution is done blank.Mouse is put to death, dissect animal, take out liver, spleen and thymus gland, weigh after blotting bloodstain with filter paper.
1.5.2 delayed allergy (DTH): mouse continuous irrigation stomach is after 30 days, and every mouse skin of abdomen is with the hair remover processing of losing hair or feathers, the about 3cm * 3cm of scope, and sensitization is evenly smeared with DNFB solution 50 μ l in the back; After 5 days, evenly be applied in the mouse right ear two sides with DNFB solution 10 μ l again, attack; After 24 hours, mouse is put to death in the cervical vertebra dislocation, and two ears about cutting take off the auricle of diameter 5mm and weigh with card punch.
1.5.3 Turnover of Mouse Peritoneal Macrophages is engulfed chicken red blood cell experiment (half intracorporal method): mouse continuous irrigation stomach is after 30 days, every mouse lumbar injection 2% chicken erythrocyte suspension 1ml.Behind the 30min, animal is put to death in the cervical vertebra dislocation, faces upward the position and is fixed on the stencil plate; Abdominal skin is cut off in the center, injects physiological saline 2ml through the abdominal cavity, rotates mouse plate 1min; Sucking-off abdominal cavity washing lotion 1ml then; Average mark drips on 2 slides, puts into the enamel box that is lined with wet gauze, in 37 ℃ of incubator incubation 30min.Incubate completely, not paster cell is removed in rinsing in physiological saline.Dry, with the fixing 20min of 1: 1 acetone methanol solution, 4% (v/v) Giemsa-phosphate buffer dyeing 3min dries with the distilled water rinsing again, counts macrophage in microscopically.
1.5.4ConA mouse spleen lymphocyte transformation experiment of inducing and NK cells in mice determination of activity (lactate dehydrogenase L DH determination method): mouse continuous irrigation stomach is after 30 days, and the aseptic spleen of getting is put to death in the cervical vertebra dislocation; Place the little plate that fills an amount of aseptic Hanks liquid; Gently spleen is torn to shreds with tweezers, shine net filtration, process single cell suspension through 200 orders; Cell suspension is divided into two parts, is respectively applied for mouse spleen lymphocyte transformation experiment and NK cells in mice determination of activity that ConA induces.
1.5.4.1ConA the mouse spleen lymphocyte transformation experiment of inducing: with Hanks liquid washed cell suspension 2 times; Each centrifugal 10min (1000r/min); Then cell is suspended in the complete culture solution of 1ml; Trypan blue dyeing counting viable count (more than 95%), the adjustment cell concentration is 3 * 106/ml.Divide two holes to add in 24 well culture plates every part of cell suspension, every hole 1ml, a hole adds 75 μ lConA liquid, and another hole is put and is cultivated 72h in the incubator as contrast.Cultivate and finish preceding 4h, every hole is inhaled and is removed supernatant 0.7ml, adds the RPMI1640 nutrient solution that 0.7ml does not contain serum, adds MTT50 μ l/ hole simultaneously, continues to cultivate 4h.After cultivating end, every hole adds 1ml acid isopropyl alcohol, mixing, dissolving.Divide then to install to 96 well culture plates, 3 parallel holes are done in every hole, measure OD value with ELIASA with the 570nm wavelength.
NK cells in mice determination of activity (lactate dehydrogenase L DH determination method): test preceding 24 hours with the target cell cultivation of going down to posterity, wash 3 times with Hanks liquid before using, using the RPMI1640 complete culture solution to adjust cell concentration is 4 * 105/ml.With Hanks liquid washed cell suspension 2 times, each centrifugal 10min (1000r/min).Abandoning supernatant upsprings cytoplasm; Add 0.5ml aqua sterilisa 20s, add 2 times of Hanks liquid of 0.5ml and 8mlHanks liquid behind the cell lysis again, centrifugal 10min (1000r/min); Resuspended with the 1ml complete medium; With 1% glacial acetic acid dilution back counting, trypan blue dyeing counting viable count (more than 95%), the adjustment cell concentration is 2 * 107/ml.Get each 100 μ l of target cell and effector cell (imitating target), add in 96 well culture plates than 50: 1; Target cell nature release aperture adds each 100 μ l of target cell and nutrient solution, the maximum release aperture of target cell adds target cell and each 100 μ l of 1%NP40, and above-mentioned each item is all established three multiple holes, and cultivation is 4 hours in 37 ℃, 5%CO2 incubator; Then with culture plate centrifugal (1500r/min) 5min; Every hole is drawn supernatant 100 μ l and is put in 96 well culture plates, adds LDH matrix liquid 100 μ l simultaneously, reaction 3min; Every hole adds the HCl30 μ l of 1mol/L, measures OD value (OD) at ELIASA 490nm place.
The result
2.1 two yeast nutritious food are to the influence of mouse internal organs/weight ratio, the result sees table 1.
Table 1 liang yeast nutritious food is to the influence of mouse internal organs/weight ratio (x ± s)
*Compare P＜0.05 with control group
Two yeast nutritious food spleen/body weight ratio and control group compare, P＞0.05, no significant difference; Thymus gland/body weight ratio and control group compare, P＜0.05, and there were significant differences.
2.2 two yeast nutritious food are seen table 2. to the influence of mouse cell immunologic function (mouse spleen lymphocyte transformation experiment and mouse delayed allergy (DTH))
Table 2 liang yeast nutritious food is to mouse cell Immune Effects (x ± s)
(1) compares P＜0.01 with control group
(2) compare P＜0.05 with control group
(3) yeast nutrition food A1-A3 group is compared P＜0.05 with yeast nutrition food B group
The OD difference of yeast nutrition food A1-A3 group lymphocyte proliferation assay is compared P＜0.01 with control group, significant difference is arranged; The swollen degree of ear is compared also P＜0.01 with control group, significant difference is arranged, and yeast nutrition food A1-A3 group compares P＜0.05 with yeast nutrition food B group, and significant difference is arranged.
Two yeast nutritious food are seen table 3 to the influence of mouse monokaryon-macrophage function (mouse carbon is cleaned up experiment, Turnover of Mouse Peritoneal Macrophages is engulfed the chicken red blood cell ability).
Table 3 liang yeast nutritious food is to the influence of mouse monokaryon-macrophage function (x ± s)
(1) compares P＜0.01 with control group
(2) compare P＜0.05 with control group
(3) yeast nutrition food A1-A3 group is compared P＜0.05 with yeast nutrition food B group
Yeast nutrition food A1-A3 group mouse carbon is cleaned up the experiment phagocytic index and is compared with control group, and there is the utmost point significant difference P＜0.01; Phagocytic rate and control group that Turnover of Mouse Peritoneal Macrophages is engulfed chicken red blood cell compare, and there is the utmost point significant difference P＜0.01.And yeast nutrition food A1-A3 group is compared P＜0.05 with yeast nutrition food B group, and significant difference is arranged.
Two yeast nutritious food are seen table 4 to the active influence of NK cells in mice.
Table 4 liang yeast nutritious food is to the active influence of NK cells in mice (x ± s)
(1) compares P＜0.01 with control group
(2) compare P＜0.05 with control group
(3) yeast nutrition food A1-A3 group is compared P＜0.01 with yeast nutrition food B group
Yeast nutrition food A1-A3 group NK cells in mice is active compares with control group, and there is the utmost point significant difference P＜0.01.And yeast nutrition food A1-A3 group is compared P＜0.01 with yeast nutrition food B group, and significant difference is arranged.
Conclusion
The yeast nutrition food (yeast nutrition food B) of this experiment through inventing with yeast nutrition food of the present invention (yeast nutrition food A1-A3) and patent " a kind of nutritious yeast foodstuff and preparation method thereof " (200510015005.2) to the mouse filling, and carry out cellular immune function experiment (mouse spleen lymphocyte transformation experiment and mouse delayed allergy (DTH)), monokaryon-macrophage function experiment (mouse carbon is cleaned up experiment, Turnover of Mouse Peritoneal Macrophages is engulfed the chicken red blood cell ability), the experiment of NK cytoactive of mouse.Experimental result shows that yeast nutrition food A1-A3 of the present invention more can significantly improve each item immunologic function of mouse than yeast nutrition food B.
More than; Invention has been described on the basis of specific preferred implementation; But those skilled in the art should understand, and under the situation of the spirit and scope of the present invention that do not depart from accompanying claims and limited, can increase multiple variation and change.
Claims (9)
1. yeast nutrition food; With the yeast is primary raw material; Comprise milk powder, maltodextrin, lactose, vegetable fat powder, calcium carbonate, starch, white granulated sugar and flavouring, essence; It is characterized in that said yeast nutrition food also comprises B family vitamin and the yeast that is rich in trace element, said component has following weight portion:
Yeast 5-97,
Milk powder 1-20,
Vegetable fat powder 1-50,
Calcium carbonate 0.1-50,
Starch 1-50,
Maltodextrin 0-50,
Lactose 0-50,
White granulated sugar 0-70,
Folic acid 0-1,
Cobastab
120-1
Cobastab
10-10,
Cobastab
20-10,
Vitamin A 0-10,
Vitamin C 0-20,
Se-enriched yeast 0-10,
Zinc-rich saccharomyces cerevisiae 0-40,
Ferrum-rich saccharomyces cerevisiae 0-10,
Cr-enriched yeast 0-10,
Microcrystalline cellulose 0-20.
2. yeast nutrition food according to claim 1 wherein, comprises the said component with following weight portion:
White granulated sugar 1-70,
Folic acid 0.00001-1,
Cobastab
120.00001-1
Cobastab
10.0001-10,
Cobastab
20.0001-10,
Vitamin A 0.0001-10,
Vitamin C 0.0001-20,
Se-enriched yeast 0.0001-10,
Zinc-rich saccharomyces cerevisiae 1-40,
Ferrum-rich saccharomyces cerevisiae 1-10,
Cr-enriched yeast 0.0001-10,
Microcrystalline cellulose 1-20.
3. yeast nutrition food according to claim 1, wherein, said yeast nutrition food further comprises one or more in the following components in part by weight:
Air-dried onion in slice 1-10,
Cocoa power 1-20,
Fruits and vegetables powder 1-20,
Sesame 1-50,
Milk tea powder 1-20,
Soymilk powder 1-20,
Oatmeal 1-20.
4. yeast nutrition food according to claim 1, wherein, said primary raw material yeast is dusty yeast or yeast milk.
5. according to each described yeast nutrition food among the claim 1-4, wherein, said ferrum-rich saccharomyces cerevisiae is by ferrous gluconate, amino acid chelated iron, ferrous sulfate, ferrous fumarate, ferrous lactate or their mixture replacements arbitrarily; Said Zinc-rich saccharomyces cerevisiae is by zinc sulfate, zinc gluconate, zinc lactate, zinc citrate, zinc-amino acid chelate or their mixture replacements arbitrarily; Said Se-enriched yeast is replaced by sodium selenite; Said flavouring is citric acid, malic acid.
6. be used for preparing the method for each described yeast nutrition food of claim 1-5; It is characterized in that; Said method comprises that said yeast and other raw materials are mixed and add water to stir according to prescription, then spray-drying and packing to obtain the yeast nutrition food of powdery.
7. be used for preparing the method for each described yeast nutrition food of claim 1-5; It is characterized in that said method comprises that said yeast is added water to stir, and carries out drying with roller drier then; Wherein baking temperature is controlled at 180 ℃; Collect and use screen filtration after the drying, add said other supplementary materials again and mix, pack at last to obtain the yeast nutrition food of snowflake shape.
8. be used for preparing the method for each described yeast nutrition food of claim 1-5; It is characterized in that; Said method comprises mixes said yeast and other raw materials according to prescription; Process tablet through steps such as granulation, drying, compressing tablets then, then through being packaged to be the yeast nutrition food of tablet.
9. be used for strengthening the application of the medicine of object cellular immune function in preparation according to each described yeast nutrition food among the claim 1-5.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101866665A CN101756216B (en) | 2008-12-16 | 2008-12-16 | Yeast nutritious food and preparation method thereof |
| JP2011522375A JP5433003B2 (en) | 2008-12-16 | 2009-09-23 | Yeast nutritional food and method for producing the same |
| PCT/CN2009/074142 WO2010069191A1 (en) | 2008-12-16 | 2009-09-23 | Nutritional yeast food and method preparing thereof |
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| CN2008101866665A CN101756216B (en) | 2008-12-16 | 2008-12-16 | Yeast nutritious food and preparation method thereof |
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| JP (1) | JP5433003B2 (en) |
| CN (1) | CN101756216B (en) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102551067B (en) * | 2011-12-13 | 2013-07-31 | 张荣斌 | Formula of oral solution for regulating immunity and preparation method thereof |
| CN102793163A (en) * | 2012-07-20 | 2012-11-28 | 惠州市鑫福来实业发展有限公司 | Calcium-iron-zinc-selenium multivitamin chewable tablet and preparation method thereof |
| CN103584072A (en) * | 2012-08-15 | 2014-02-19 | 安琪酵母股份有限公司 | Fatigue-alleviating composition, preparation method and application thereof |
| CN103053899B (en) * | 2012-08-22 | 2013-12-25 | 浙江省海洋开发研究院 | Kelp extractive nutrition enhancer and preparation method thereof |
| CN104026540B (en) * | 2013-03-05 | 2016-08-10 | 安琪酵母股份有限公司 | A kind of infant flavoring agent and preparation method thereof |
| CN103478576A (en) * | 2013-08-30 | 2014-01-01 | 兴化市联富食品有限公司 | Five-wheat seedlings series products and production method thereof |
| US20160326484A1 (en) | 2013-12-26 | 2016-11-10 | Hill's Pet Nutrition, Inc. | High nutrient yeast |
| CN104522628B (en) * | 2014-12-25 | 2017-04-19 | 平昌县欣旗食品有限公司 | Dried edible mushrooms and processing process thereof |
| CN104886567A (en) * | 2015-05-13 | 2015-09-09 | 宁波北仑戌鸿农业科技有限公司 | Selenium containing health-care food |
| CN105146666B (en) * | 2015-08-11 | 2018-01-19 | 广东江门生物技术开发中心有限公司 | A kind of solid beverage for supplementing B family vitamin and preparation method thereof |
| CN105942500B (en) * | 2016-05-03 | 2018-11-27 | 宣城柏维力生物工程有限公司 | Selenium-rich yeast tablet and preparation method thereof |
| CN106165893A (en) * | 2016-08-19 | 2016-11-30 | 江西中天医药生物有限公司 | A kind of supplementary human body chromium, selenium and ascorbic health food |
| CN107581253A (en) * | 2017-08-31 | 2018-01-16 | 广州富诺营养科技有限公司 | A kind of Zinc-rich saccharomyces cerevisiae solid beverage and preparation method thereof |
| CN110063501A (en) * | 2019-05-05 | 2019-07-30 | 上海交通大学 | A kind of Multifunctional flocculation yeast dry powder and its application |
| CN110692732A (en) * | 2019-11-05 | 2020-01-17 | 东北农业大学 | Preparation method of selenium-rich fermented soymilk |
| CN111771974A (en) * | 2020-07-23 | 2020-10-16 | 武汉生物工程学院 | Preparation method of set-type zinc-rich yogurt |
| CN115500504A (en) * | 2021-06-07 | 2022-12-23 | 安琪纽特股份有限公司 | Non-sticky instant yeast food and preparation method thereof |
| US20230218664A1 (en) * | 2022-01-10 | 2023-07-13 | Tian Yu Wang | Health food for promotion of quality of sleepy and metabolism |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1927006A (en) * | 2005-09-07 | 2007-03-14 | 天津天士力制药股份有限公司 | Nutritious yeast foodstuff and its preparing process |
| CN101822407A (en) * | 2009-03-04 | 2010-09-08 | 兰敬墨 | Compound protein beverage and production method thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1108478A (en) * | 1994-03-16 | 1995-09-20 | 黑龙江省林甸乳制品厂 | Selenium-intensified milk powder |
| CN1685888A (en) * | 2005-04-05 | 2005-10-26 | 苟春虎 | Kangshiming sour milk tablet |
| CN101258935A (en) * | 2007-03-07 | 2008-09-10 | 孙宪育 | Health-care spirulina food |
| CN101032515A (en) * | 2007-04-20 | 2007-09-12 | 张竟 | Healthy product for improving immunity |
| CN101361567B (en) * | 2007-08-07 | 2012-09-19 | 安琪酵母股份有限公司 | Multi-nutrient composite yeast powder |
| CN101156870A (en) * | 2007-09-25 | 2008-04-09 | 上海育生堂科技有限公司 | A composition for improving growth development and help in improving anamnesis as well as its preparation method |
-
2008
- 2008-12-16 CN CN2008101866665A patent/CN101756216B/en active Active
-
2009
- 2009-09-23 JP JP2011522375A patent/JP5433003B2/en active Active
- 2009-09-23 WO PCT/CN2009/074142 patent/WO2010069191A1/en active Application Filing
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1927006A (en) * | 2005-09-07 | 2007-03-14 | 天津天士力制药股份有限公司 | Nutritious yeast foodstuff and its preparing process |
| CN101822407A (en) * | 2009-03-04 | 2010-09-08 | 兰敬墨 | Compound protein beverage and production method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 刘秀河，艾连中，吴艳.益生菌AB奶片的研制.《现代食品科技》.2006,第22卷(第3期), * |
| 毛建兰.普通面包的加工工艺研究.《四川食品与发酵》.2008,第44卷(第3期), * |
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| Publication number | Publication date |
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| CN101756216A (en) | 2010-06-30 |
| JP2011530300A (en) | 2011-12-22 |
| JP5433003B2 (en) | 2014-03-05 |
| WO2010069191A1 (en) | 2010-06-24 |
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