CN102551067B - Formula of oral solution for regulating immunity and preparation method thereof - Google Patents
Formula of oral solution for regulating immunity and preparation method thereof Download PDFInfo
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- CN102551067B CN102551067B CN 201110414046 CN201110414046A CN102551067B CN 102551067 B CN102551067 B CN 102551067B CN 201110414046 CN201110414046 CN 201110414046 CN 201110414046 A CN201110414046 A CN 201110414046A CN 102551067 B CN102551067 B CN 102551067B
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Abstract
The invention discloses a formula of an oral solution for regulating immunity. The oral solution is prepared from the following raw materials in part by weight: 10 to 20 parts of pseudo-ginseng, 15 to 25 parts of white paeony root, 10 to 30 parts of dwarf lilyturf tuber, 10 to 30 parts of Szechuan lovage rhizome, 10 to 20 parts of coastal glehnia root, 20 to 30 parts of donkey-hide glue, 10 to 15 parts of astragalus, 20 to 30 parts of Chinese date, 20 to 30 parts of fructus amomi, 0.5 to 1.5 parts of zinc, 0.08 to 1.2 parts of chromium yeast extracting solution, 1.5 to 4.5 parts of sorbic acid and 10 to 30 parts of yam, medlar and lily extracting solution. The oral solution can resist anoxia, cold, fatigue and microwave radiation, various Chinese medicines with tonifying effects are combined, the formula is reasonable, a preparation process is simple and feasible, and a health care effect is obvious; and the oral solution is good in mouthfeel and convenient to take, and can achieve the effects of fully regulating internal secretion and enhancing immunity.
Description
Technical field
The present invention relates to a kind of oral liquid prescription of regulating immunity, belong to the health food technology field.
Background technology
Along with the raising of economic construction, science and technology development and living standards of the people, people are deep day by day with healthy understanding of importance to the value of life, more and more pay attention to.Meanwhile, various be intended to the nutritional health food that human body plays immunoregulation effect is developed develop, for people's public health work with improve the quality of living and make positive contribution.Yet, in miscellaneous health food, also mix the category inferior that does not much at all have health-care effect is arranged, the some of them Ricipe for health care food is unreasonable, yang-tonifying does not know to educate the moon, enrich blood and do not know strong gas, benefit property is inclined to one side one, and side effect is big, for example, Chinese cassia tree, monkshood are partial to supporing yang and are lit a fire, genseng, wilsonii excitability are strong excessively, can cause constipation again, all can not obey for a long time, the development of some health foods, the producer do not add consideration or inconsiderate to this, thereby can not get desirable health-care effect after edible.
Summary of the invention
The objective of the invention is to: provide a kind of have unique pharmacological action, prescription rationally, can effectively strengthen the immunological regulating oral liquid of body immunity, thereby can effectively solve above-mentioned problems of the prior art.
The object of the invention realizes by following technical proposals: a kind of oral liquid of regulating immunity, and its composition of raw materials is prepared with following weight ratio:
Pseudo-ginseng 10-20, root of herbaceous peony 15-25, the tuber of dwarf lilyturf 10-30, Ligusticum wallichii 10-30, radix glehniae 10-20, donkey-hide gelatin 20-30, Radix Astragali 10-15, date 20-30, fructus amomi 20-30, zinc 0.5-1.5, chromium yeast extract 0.08-1.2, sorbic acid 1.5-4.5 and Chinese yam, the fruit of Chinese wolfberry, lily extract 10-30.
As a kind of optimal way, the composition of raw materials of described oral liquid is prepared with following weight ratio:
Pseudo-ginseng 12, the root of herbaceous peony 15, the tuber of dwarf lilyturf 15, Ligusticum wallichii 15, radix glehniae 15, donkey-hide gelatin 20, the Radix Astragali 11, date 24, fructus amomi 24, zinc 0.8, chromium yeast extract 0.09, sorbic acid 1.8 and Chinese yam, the fruit of Chinese wolfberry, lily extract 15.
As a kind of optimal way, the composition of raw materials of described oral liquid is prepared with following weight ratio:
Pseudo-ginseng 16, the root of herbaceous peony 18, the tuber of dwarf lilyturf 18, Ligusticum wallichii 20, radix glehniae 18, donkey-hide gelatin 22, the Radix Astragali 13, date 25, fructus amomi 25, zinc 0.8, chromium yeast extract 1.2, sorbic acid 4.5 and Chinese yam, the fruit of Chinese wolfberry, lily extract 30.
As a kind of optimal way, the zinc in the described oral liquid is provided by zinc preparation, and described zinc preparation can adopt zinc sulfate, zinc carbonate, zinc lactate, zinc chloride, zinc acetate, glycine zine, zinc gluconate etc.
As a kind of optimal way, the chromium content in the described chromium yeast extract is 25-50 μ g/ml.Chromium content in the described chromium yeast extract is adjusted by chromic salts, and described chromic salts can adopt chromium picolinate, chromium chloride, emulsification chromium or various amino acid chromiums etc.
Compared with prior art, beneficial effect of the present invention: oral liquid provided by the invention can play anti-anoxic, cold resistance, antifatigue, anti-microwave radiation, compatibility has the Chinese medicine of multiple benefiting action, prescription rationally, preparation is simple, and health-care effect is obvious, and this oral liquid mouthfeel is good, taking convenience can play the effect of abundant adjusting endocrine, enhancing immunity.
The specific embodiment
In order to make purpose of the present invention, technical scheme and advantage clearer,, the present invention is further elaborated below in conjunction with embodiment.Should be appreciated that specific embodiment described herein only in order to explanation the present invention, and be not used in qualification the present invention.
Disclosed all features in this specification, or the step in disclosed all methods or the process, except the speciality and/or step of mutual repulsion, all can make up by any way, unless special narration all can be replaced by other equivalences or the alternative features with similar purpose, promptly, unless special narration, an embodiment in a series of equivalences of each feature or the similar characteristics.
A kind of oral liquid prescription of regulating immunity, its composition of raw materials is prepared with following weight ratio: pseudo-ginseng 10-20, root of herbaceous peony 15-25, the tuber of dwarf lilyturf 10-30, Ligusticum wallichii 10-30, radix glehniae 10-20, donkey-hide gelatin 20-30, Radix Astragali 10-15, date 20-30, fructus amomi 20-30, zinc 0.5-1.5, chromium yeast extract 0.08-1.2, sorbic acid 1.5-4.5 and Chinese yam, the fruit of Chinese wolfberry, lily extract 10-30.
Wherein: zinc preparation can adopt zinc sulfate, zinc carbonate, zinc lactate, zinc chloride, zinc acetate, glycine zine, zinc gluconate etc.
Zinc is the constituent of insulin, contains two zinc atoms in each insulin molecule.Zinc can assist glucose to turn round on cell membrane, plays a part very important to the conversion of carbohydrate.So zinc deficiency can make pancreas islet α, the β cell number descends, and glicentin and insulin secretion all reduce, and make abnormal carbohydrate metabolism.
Trivalent chromium can form the organic matter of biologically active, becomes GTF (GTF), and it is a kind of " collaborative hormone " of insulin and strengthen the effect of insulin.GTF participates in forming insulin ternary compound and membrane receptor, makes insulin function stable, suppresses insulinase, can keep the amount of insulin, and enhancing and insulin binding.Scarce chromium can cause surrounding tissue, and internally exogenous insulin sensitiveness descends.Then cause that sugar tolerance reduces.
Embodiment 1
A kind of oral liquid prescription of regulating immunity, its composition of raw materials is prepared with following weight ratio:
Pseudo-ginseng 12, the root of herbaceous peony 15, the tuber of dwarf lilyturf 15, Ligusticum wallichii 15, radix glehniae 15, donkey-hide gelatin 20, the Radix Astragali 11, date 24, fructus amomi 24, zinc 0.8, chromium yeast extract 0.09, sorbic acid 1.8 and Chinese yam, the fruit of Chinese wolfberry, lily extract 15.
Oral liquid is prepared with following step:
1) cleaning, drying: with pseudo-ginseng, the root of herbaceous peony, the tuber of dwarf lilyturf, Ligusticum wallichii, radix glehniae, donkey-hide gelatin, the Radix Astragali, date, fructus amomi selected after, cleaning, drying;
2) distillation: pseudo-ginseng, radix glehniae, Ligusticum wallichii, fructus amomi are extracted its volatile oil with the way of distillation, the device harvesting in addition of the aqueous solution after the distillation;
3) diacolation: the dregs of a decoction after pseudo-ginseng, Ligusticum wallichii, the fructus amomi distillation and the root of herbaceous peony, the tuber of dwarf lilyturf, the Radix Astragali are made solvent by percolation (2000 editions " Chinese pharmacopoeia appendix 10) with 70% ethanol, flood after 24 hours, with the speed diacolation of per minute 1-3 milliliter, the liquid of will filtering is then collected; Simultaneously ethanol is reclaimed, standby;
4) extraction of yeast chromium: the brewer's yeast mechanical breaking-wall method that chrome content is approximately 30-60 μ g/g adds water (30 ℃) constant temperature by 1: 2 (W/W) and soaked 1-2 hour, press chromium yeast weight about 1: 1 (W/W) and add ethanolic solution, (ethanol content is 95%) filtered after lixiviate 0.5-1 hour, obtained the yeast chromium extract.Chrome content is 10-15 μ g/ml.
With chromium picolinate or chromium chloride, Chromic lactate, amino acid chromium are adjusted to 25 μ g-50 μ g/ml with the chromium content of chromium yeast extract, add an amount of thickener, stir evenly standby.
5) preparation of Chinese yam, the fruit of Chinese wolfberry, lily extract: selected Chinese yam, the fruit of Chinese wolfberry, lily dry product, impurity elimination was soaked 2 hours in 1: 2.8 (W/W) ratio, decocted 0.5 hour, and filtered, filter residue is added the water of commercial weight, decocted 30 minutes, and filtered, merge twice filtrate promptly.
6) decoct: said medicine and date boiling secondary, collecting decoction leaches standby;
7) molten: donkey-hide gelatin is added in the rustless steel container, and it is an amount of to add water, heats to 80 ℃, treat its molten after, other usefulness of purchasing;
8) concentrate: above-mentioned percolate, decoction liquor, molten liquid are mixed and slowly stirring, it is fully mixed, leave standstill, filter, filtrate concentrates;
9) adjust: described concentrate is mixed with volatile oil in the above-mentioned steps 2, add an amount of anticorrisive agent, flavouring, adjust pH value, regulate total amount, promptly get stoste;
10) sterilization: under low temperature (≤40 ℃), handled 50 minutes with ultrasonic wave;
11) packing: with above-mentioned sterilized solution according to the every pouch packing of 15g.
In order to replenish the zinc and the chromium of needed by human body, recommended amounts in conjunction with U.S. NRC standard and China NI, suitably increased magnitude of recruitment, particularly in recent years, nutritive value to chromium has carried out fruitful research both at home and abroad, find that chromium not only plays an important role in glycometabolism, and also bringing into play very important effect in fat metabolism and protein metabolism process.Mend chromium and have reliable theoretical foundation and significant effect.
Embodiment 2
A kind of oral liquid prescription of regulating immunity, its composition of raw materials is prepared with following weight ratio: pseudo-ginseng 16, the root of herbaceous peony 18, the tuber of dwarf lilyturf 18, Ligusticum wallichii 20, radix glehniae 18, donkey-hide gelatin 22, the Radix Astragali 13, date 25, fructus amomi 25, zinc 0.8, chromium yeast extract 1.2, sorbic acid 4.5 and Chinese yam, the fruit of Chinese wolfberry, lily extract 30.
Embodiment 3
A kind of oral liquid prescription of regulating immunity, its composition of raw materials is prepared with following weight ratio: pseudo-ginseng 10, the root of herbaceous peony 21, the tuber of dwarf lilyturf 25.5, Ligusticum wallichii 16, radix glehniae 17, donkey-hide gelatin 21, the Radix Astragali 13, date 25, fructus amomi 25, zinc 0.7, chromium yeast extract 0.08, sorbic acid 1.8 and Chinese yam, the fruit of Chinese wolfberry, lily extract 25.
The above only is preferred embodiment of the present invention, not in order to restriction the present invention, all any modifications of being done within the spirit and principles in the present invention, is equal to and replaces and improvement etc., all should be included within protection scope of the present invention.
Claims (4)
1. oral liquid of regulating immunity, it is characterized in that: its composition of raw materials is prepared with following weight ratio:
Pseudo-ginseng 10-20, root of herbaceous peony 15-25, the tuber of dwarf lilyturf 10-30, Ligusticum wallichii 10-30, radix glehniae 10-20, donkey-hide gelatin 20-30, Radix Astragali 10-15, date 20-30, fructus amomi 20-30, zinc 0.5-1.5, chromium yeast extract 0.08-1.2, sorbic acid 1.5-4.5 and Chinese yam, the fruit of Chinese wolfberry, lily extract 10-30;
Described chromium yeast extract is to be the brewer's yeast mechanical breaking-wall method of 30-60 μ g/g with chrome content, added water soaked 1-2 hour at 30 ℃ of following constant temperature by weight 1: 2, adding ethanol content at 1: 1 by chromium yeast and ethanol weight ratio is 95% ethanolic solution, filter after lixiviate 0.5-1 hour, obtain the chromium yeast extract, chrome content is 10-15 μ g/ml;
With chromium picolinate or chromium chloride, Chromic lactate, amino acid chromium are adjusted to 25-50 μ g/ml, add an amount of thickener, stir evenly standby with the chromium content of chromium yeast extract;
The preparation of described Chinese yam, the fruit of Chinese wolfberry, lily extract: selected Chinese yam, the fruit of Chinese wolfberry, lily dry product, impurity elimination was soaked 2 hours by weight 1: 2.8 ratio, decocted 0.5 hour, and filtered, filter residue is added the water of commercial weight, decocted 30 minutes, and filtered, merge twice filtrate promptly.
2. the oral liquid of adjusting immunity as claimed in claim 1 is characterized in that: its composition of raw materials is prepared with following weight ratio:
Pseudo-ginseng 12, the root of herbaceous peony 15, the tuber of dwarf lilyturf 15, Ligusticum wallichii 15, radix glehniae 15, donkey-hide gelatin 20, the Radix Astragali 11, date 24, fructus amomi 24, zinc 0.8, chromium yeast extract 0.09, sorbic acid 1.8 and Chinese yam, the fruit of Chinese wolfberry, lily extract 15.
3. the oral liquid of adjusting immunity as claimed in claim 1 is characterized in that: its composition of raw materials is prepared with following weight ratio:
Pseudo-ginseng 16, the root of herbaceous peony 18, the tuber of dwarf lilyturf 18, Ligusticum wallichii 20, radix glehniae 18, donkey-hide gelatin 22, the Radix Astragali 13, date 25, fructus amomi 25, zinc 0.8, chromium yeast extract 1.2, sorbic acid 4.5 and Chinese yam, the fruit of Chinese wolfberry, lily extract 30.
4. the oral liquid of adjusting immunity as claimed in claim 1 is characterized in that: described zinc is provided by zinc preparation, and described zinc preparation is at least a in zinc sulfate, zinc carbonate, zinc lactate, zinc chloride, zinc acetate, glycine zine, the zinc gluconate.
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| Application Number | Priority Date | Filing Date | Title |
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| CN 201110414046 CN102551067B (en) | 2011-12-13 | 2011-12-13 | Formula of oral solution for regulating immunity and preparation method thereof |
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| CN 201110414046 CN102551067B (en) | 2011-12-13 | 2011-12-13 | Formula of oral solution for regulating immunity and preparation method thereof |
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| CN102551067A CN102551067A (en) | 2012-07-11 |
| CN102551067B true CN102551067B (en) | 2013-07-31 |
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| CN103800425A (en) * | 2012-11-12 | 2014-05-21 | 苏州市洋海电子有限公司 | Composition of organic zinc and astragalus extract |
| CN108066599B (en) * | 2017-12-28 | 2020-08-21 | 神威药业集团有限公司 | Composition for enhancing immunity and assisting in radiation resistance and preparation method and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101579364A (en) * | 2008-05-14 | 2009-11-18 | 北京和润创新医药科技发展有限公司 | Pharmaceutical composition and preparation method thereof |
| CN101756216A (en) * | 2008-12-16 | 2010-06-30 | 安琪酵母股份有限公司 | Yeast nutritious food and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101579364A (en) * | 2008-05-14 | 2009-11-18 | 北京和润创新医药科技发展有限公司 | Pharmaceutical composition and preparation method thereof |
| CN101756216A (en) * | 2008-12-16 | 2010-06-30 | 安琪酵母股份有限公司 | Yeast nutritious food and preparation method thereof |
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