CN101744092B - 一种羊血红蛋白多肽粉及其制备方法 - Google Patents
一种羊血红蛋白多肽粉及其制备方法 Download PDFInfo
- Publication number
- CN101744092B CN101744092B CN2010100009370A CN201010000937A CN101744092B CN 101744092 B CN101744092 B CN 101744092B CN 2010100009370 A CN2010100009370 A CN 2010100009370A CN 201010000937 A CN201010000937 A CN 201010000937A CN 101744092 B CN101744092 B CN 101744092B
- Authority
- CN
- China
- Prior art keywords
- sheep
- sheep hemoglobin
- polypeptide powder
- hemoglobin
- rcf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 241001494479 Pecora Species 0.000 title claims abstract description 112
- 102000001554 Hemoglobins Human genes 0.000 title claims abstract description 88
- 108010054147 Hemoglobins Proteins 0.000 title claims abstract description 88
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 44
- 102000004196 processed proteins & peptides Human genes 0.000 title claims abstract description 43
- 229920001184 polypeptide Polymers 0.000 title claims abstract description 42
- 239000000843 powder Substances 0.000 title claims abstract description 40
- 238000002360 preparation method Methods 0.000 title claims abstract description 24
- 210000004369 blood Anatomy 0.000 claims abstract description 23
- 239000008280 blood Substances 0.000 claims abstract description 23
- 108090000526 Papain Proteins 0.000 claims abstract description 15
- 239000004365 Protease Substances 0.000 claims abstract description 15
- 229940055729 papain Drugs 0.000 claims abstract description 15
- 235000019834 papain Nutrition 0.000 claims abstract description 15
- 239000012528 membrane Substances 0.000 claims abstract description 8
- 238000000108 ultra-filtration Methods 0.000 claims abstract description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 238000000034 method Methods 0.000 claims abstract description 5
- 239000001509 sodium citrate Substances 0.000 claims abstract description 5
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 claims abstract description 5
- 229940038773 trisodium citrate Drugs 0.000 claims abstract description 5
- 239000000243 solution Substances 0.000 claims description 51
- 239000012530 fluid Substances 0.000 claims description 14
- 239000000413 hydrolysate Substances 0.000 claims description 14
- 102000004506 Blood Proteins Human genes 0.000 claims description 7
- 108010017384 Blood Proteins Proteins 0.000 claims description 7
- 210000002381 plasma Anatomy 0.000 claims description 7
- 239000012460 protein solution Substances 0.000 claims description 7
- 230000001105 regulatory effect Effects 0.000 claims description 7
- 238000003756 stirring Methods 0.000 claims description 7
- 239000006228 supernatant Substances 0.000 claims description 7
- 238000009413 insulation Methods 0.000 claims description 4
- 230000003064 anti-oxidating effect Effects 0.000 abstract description 2
- 239000000203 mixture Substances 0.000 abstract description 2
- 231100000957 no side effect Toxicity 0.000 abstract description 2
- 235000016709 nutrition Nutrition 0.000 abstract description 2
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 abstract 2
- 230000036772 blood pressure Effects 0.000 abstract 1
- 238000005119 centrifugation Methods 0.000 abstract 1
- 238000007865 diluting Methods 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000002778 food additive Substances 0.000 abstract 1
- 235000013373 food additive Nutrition 0.000 abstract 1
- 230000007365 immunoregulation Effects 0.000 abstract 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 9
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
- 235000013376 functional food Nutrition 0.000 description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 238000004108 freeze drying Methods 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 229910052708 sodium Inorganic materials 0.000 description 3
- 239000011734 sodium Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- CDAWCLOXVUBKRW-UHFFFAOYSA-N 2-aminophenol Chemical compound NC1=CC=CC=C1O CDAWCLOXVUBKRW-UHFFFAOYSA-N 0.000 description 1
- 102400000967 Bradykinin Human genes 0.000 description 1
- 101800004538 Bradykinin Proteins 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- QXZGBUJJYSLZLT-UHFFFAOYSA-N H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH Natural products NC(N)=NCCCC(N)C(=O)N1CCCC1C(=O)N1C(C(=O)NCC(=O)NC(CC=2C=CC=CC=2)C(=O)NC(CO)C(=O)N2C(CCC2)C(=O)NC(CC=2C=CC=CC=2)C(=O)NC(CCCN=C(N)N)C(O)=O)CCC1 QXZGBUJJYSLZLT-UHFFFAOYSA-N 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 208000001953 Hypotension Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 239000008896 Opium Substances 0.000 description 1
- 238000009098 adjuvant therapy Methods 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- QXZGBUJJYSLZLT-FDISYFBBSA-N bradykinin Chemical compound NC(=N)NCCC[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1[C@H](C(=O)NCC(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CO)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)CCC1 QXZGBUJJYSLZLT-FDISYFBBSA-N 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000007872 degassing Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 229940088598 enzyme Drugs 0.000 description 1
- 235000020776 essential amino acid Nutrition 0.000 description 1
- 239000003797 essential amino acid Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 230000001631 hypertensive effect Effects 0.000 description 1
- 208000021822 hypotensive Diseases 0.000 description 1
- 230000001077 hypotensive effect Effects 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 229960001027 opium Drugs 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 239000010865 sewage Substances 0.000 description 1
Landscapes
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
Claims (8)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2010100009370A CN101744092B (zh) | 2010-01-21 | 2010-01-21 | 一种羊血红蛋白多肽粉及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2010100009370A CN101744092B (zh) | 2010-01-21 | 2010-01-21 | 一种羊血红蛋白多肽粉及其制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101744092A CN101744092A (zh) | 2010-06-23 |
CN101744092B true CN101744092B (zh) | 2012-02-15 |
Family
ID=42472170
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2010100009370A Expired - Fee Related CN101744092B (zh) | 2010-01-21 | 2010-01-21 | 一种羊血红蛋白多肽粉及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN101744092B (zh) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105249479A (zh) * | 2015-09-08 | 2016-01-20 | 浙江海洋学院 | 金枪鱼血为原料的抗氧化保健食品的制备方法 |
CN105838764A (zh) * | 2016-05-05 | 2016-08-10 | 青海大学 | 一种酶法制备藏羊血多肽的方法 |
CN106191188B (zh) * | 2016-08-09 | 2020-01-07 | 广东海洋大学 | 一种鲎血浆蛋白的水解方法 |
CN108148881A (zh) * | 2017-12-29 | 2018-06-12 | 浦江县美泽生物科技有限公司 | 血红蛋白多肽粉的制备方法 |
CN108056271A (zh) * | 2017-12-29 | 2018-05-22 | 浦江县协盈动物饲料技术开发有限公司 | 提高幼猪成活率的饲料的制备方法 |
-
2010
- 2010-01-21 CN CN2010100009370A patent/CN101744092B/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN101744092A (zh) | 2010-06-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102048022B (zh) | 一种无水解味、无苦味的大豆多肽及其制备方法与应用 | |
CN104004813B (zh) | 一种香菇生物活性肽的制备 | |
CN101744092B (zh) | 一种羊血红蛋白多肽粉及其制备方法 | |
CN101766251A (zh) | 从猪血中提取改性血浆蛋白粉、补血活性肽的方法 | |
CN102648724B (zh) | 一种藤茶的制备方法 | |
CN101643767A (zh) | 一种从杏仁粕中制备杏仁肽的方法 | |
CN104996715B (zh) | 一种复合发酵法制备小麦胚芽多肽的工艺 | |
CN107164447A (zh) | 一种利用鳕鱼加工副产物制备抗氧化肽的方法 | |
CN102477004A (zh) | 一种利用超滤技术从牡蛎中提取天然牛磺酸的方法 | |
CN101715916A (zh) | 富含食用菌营养成分的全麦食品制作方法 | |
CN106666484B (zh) | 鲟鱼复合粉、鲟鱼骨酒及应用 | |
CN110862433A (zh) | 一种火麻肽的制备工艺方法 | |
CN104256828A (zh) | 一种小麦胚芽多肽饮料的制备方法 | |
CN105077169B (zh) | 一种富含大豆多糖保健酱油及其制备方法 | |
CN111165708A (zh) | 一种蛤蜊肽舒缓固体饮料的制备方法 | |
CN105063144A (zh) | 一种利用猪血红蛋白制取抗菌肽的方法 | |
CN109234345A (zh) | 一种酶解猪皮制备抗氧化肽的方法 | |
CN107988299A (zh) | 一种利用松花粉粕制备抗氧化松花粉肽的方法 | |
CN106173186A (zh) | 一种高值化综合利用小麦胚芽制备多肽的新方法 | |
CN116445460B (zh) | 一种降血压和抗氧化肽粉制备及其在奶粉中的应用 | |
CN101755997B (zh) | 一种羊血红素肽及制备方法 | |
CN103014106B (zh) | 广昌白莲中抗氧化多肽的提取方法 | |
Skrzypczak et al. | Effects of probiotic fermentation of selected milk and whey protein preparations on bioactive and technological properties | |
CN102586115A (zh) | 一种利用四环素菌渣好氧生产酵母浸膏的方法 | |
CN105685753A (zh) | 固体饮料及其制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Sheep hemoglobin polypeptide powder and preparation method thereof Effective date of registration: 20120917 Granted publication date: 20120215 Pledgee: Jilin credit guarantee investment Co., Ltd. Pledgor: Liaoyuan Qiming Biotechnology Development Co., Ltd. Registration number: 2012990000531 |
|
PLDC | Enforcement, change and cancellation of contracts on pledge of patent right or utility model | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20130912 Granted publication date: 20120215 Pledgee: Jilin credit guarantee investment Co., Ltd. Pledgor: Liaoyuan Qiming Biotechnology Development Co., Ltd. Registration number: 2012990000531 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Sheep hemoglobin polypeptide powder and preparation method thereof Effective date of registration: 20130913 Granted publication date: 20120215 Pledgee: Jilin credit guarantee investment Co., Ltd. Pledgor: Liaoyuan Qiming Biotechnology Development Co., Ltd. Registration number: 2013990000675 |
|
PLDC | Enforcement, change and cancellation of contracts on pledge of patent right or utility model | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20140922 Granted publication date: 20120215 Pledgee: Jilin credit guarantee Investment Group Co., Ltd. Pledgor: Liaoyuan Qiming Biotechnology Development Co., Ltd. Registration number: 2013990000675 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Sheep hemoglobin polypeptide powder and preparation method thereof Effective date of registration: 20140923 Granted publication date: 20120215 Pledgee: Jilin credit guarantee Investment Group Co., Ltd. Pledgor: Liaoyuan Qiming Biotechnology Development Co., Ltd. Registration number: 2014990000784 |
|
PLDC | Enforcement, change and cancellation of contracts on pledge of patent right or utility model | ||
PM01 | Change of the registration of the contract for pledge of patent right |
Change date: 20140922 Registration number: 2013990000675 Pledgee after: Jilin credit guarantee Investment Group Co., Ltd. Pledgee before: Jilin credit guarantee investment Co., Ltd. |
|
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20150930 Granted publication date: 20120215 Pledgee: Jilin credit guarantee Investment Group Co., Ltd. Pledgor: Liaoyuan Qiming Biotechnology Development Co., Ltd. Registration number: 2014990000784 |
|
PLDC | Enforcement, change and cancellation of contracts on pledge of patent right or utility model | ||
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120215 Termination date: 20180121 |