CN101683530A - 不会引起液体潴流、水肿或充血性心力衰竭的新ppar配体 - Google Patents

不会引起液体潴流、水肿或充血性心力衰竭的新ppar配体 Download PDF

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Publication number
CN101683530A
CN101683530A CN200910163754A CN200910163754A CN101683530A CN 101683530 A CN101683530 A CN 101683530A CN 200910163754 A CN200910163754 A CN 200910163754A CN 200910163754 A CN200910163754 A CN 200910163754A CN 101683530 A CN101683530 A CN 101683530A
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ppar
disease
chemical compound
receptor
treatment
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CN200910163754A
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Chinese (zh)
Inventor
哈里哈·A·珀沙德辛
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Bethesda Pharmaceuticals Inc
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Bethesda Pharmaceuticals Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31721501&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN101683530(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bethesda Pharmaceuticals Inc filed Critical Bethesda Pharmaceuticals Inc
Publication of CN101683530A publication Critical patent/CN101683530A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Lubricants (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Materials For Medical Uses (AREA)
CN200910163754A 2002-08-10 2003-08-08 不会引起液体潴流、水肿或充血性心力衰竭的新ppar配体 Pending CN101683530A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US40242502P 2002-08-10 2002-08-10
US60/402,425 2002-08-10
US45521103P 2003-03-15 2003-03-15
US60/455,211 2003-03-15
US10/627,372 US7232828B2 (en) 2002-08-10 2003-07-24 PPAR Ligands that do not cause fluid retention, edema or congestive heart failure
US10/627,372 2003-07-24

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNB038240513A Division CN100548293C (zh) 2002-08-10 2003-08-08 不会引起液体潴流、水肿或充血性心力衰竭的新ppar配体

Publications (1)

Publication Number Publication Date
CN101683530A true CN101683530A (zh) 2010-03-31

Family

ID=31721501

Family Applications (6)

Application Number Title Priority Date Filing Date
CN200910163751A Pending CN101683528A (zh) 2002-08-10 2003-08-08 不会引起液体潴流、水肿或充血性心力衰竭的新ppar配体
CN200910163752A Pending CN101683529A (zh) 2002-08-10 2003-08-08 不会引起液体潴流、水肿或充血性心力衰竭的新ppar配体
CN200910163754A Pending CN101683530A (zh) 2002-08-10 2003-08-08 不会引起液体潴流、水肿或充血性心力衰竭的新ppar配体
CN200910163755A Pending CN101683531A (zh) 2002-08-10 2003-08-08 不会引起液体潴流、水肿或充血性心力衰竭的新ppar配体
CN200910163753A Pending CN101683335A (zh) 2002-08-10 2003-08-08 不会引起液体潴流、水肿或充血性心力衰竭的新ppar配体
CNB038240513A Expired - Lifetime CN100548293C (zh) 2002-08-10 2003-08-08 不会引起液体潴流、水肿或充血性心力衰竭的新ppar配体

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CN200910163751A Pending CN101683528A (zh) 2002-08-10 2003-08-08 不会引起液体潴流、水肿或充血性心力衰竭的新ppar配体
CN200910163752A Pending CN101683529A (zh) 2002-08-10 2003-08-08 不会引起液体潴流、水肿或充血性心力衰竭的新ppar配体

Family Applications After (3)

Application Number Title Priority Date Filing Date
CN200910163755A Pending CN101683531A (zh) 2002-08-10 2003-08-08 不会引起液体潴流、水肿或充血性心力衰竭的新ppar配体
CN200910163753A Pending CN101683335A (zh) 2002-08-10 2003-08-08 不会引起液体潴流、水肿或充血性心力衰竭的新ppar配体
CNB038240513A Expired - Lifetime CN100548293C (zh) 2002-08-10 2003-08-08 不会引起液体潴流、水肿或充血性心力衰竭的新ppar配体

Country Status (15)

Country Link
US (8) US7232828B2 (US07812046-20101012-C00002.png)
EP (6) EP1886683B1 (US07812046-20101012-C00002.png)
JP (3) JP4669285B2 (US07812046-20101012-C00002.png)
KR (4) KR100830861B1 (US07812046-20101012-C00002.png)
CN (6) CN101683528A (US07812046-20101012-C00002.png)
AT (3) ATE536183T1 (US07812046-20101012-C00002.png)
AU (2) AU2003259081B2 (US07812046-20101012-C00002.png)
CA (1) CA2494909C (US07812046-20101012-C00002.png)
DE (2) DE60334942D1 (US07812046-20101012-C00002.png)
DK (2) DK1886683T3 (US07812046-20101012-C00002.png)
ES (2) ES2288631T3 (US07812046-20101012-C00002.png)
HK (2) HK1078021A1 (US07812046-20101012-C00002.png)
MX (1) MXPA05001543A (US07812046-20101012-C00002.png)
PL (1) PL375189A1 (US07812046-20101012-C00002.png)
WO (1) WO2004014308A2 (US07812046-20101012-C00002.png)

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