ATE167861T1 - 1,2,4-oxadiazolyl oder 1,2,4-thiadiazolyl- derivate als angiotensin ii antagonisten - Google Patents

1,2,4-oxadiazolyl oder 1,2,4-thiadiazolyl- derivate als angiotensin ii antagonisten

Info

Publication number
ATE167861T1
ATE167861T1 AT93114754T AT93114754T ATE167861T1 AT E167861 T1 ATE167861 T1 AT E167861T1 AT 93114754 T AT93114754 T AT 93114754T AT 93114754 T AT93114754 T AT 93114754T AT E167861 T1 ATE167861 T1 AT E167861T1
Authority
AT
Austria
Prior art keywords
angiotensin
action
oxadiazolyl
antagonists
thiadiazolyl derivatives
Prior art date
Application number
AT93114754T
Other languages
English (en)
Inventor
Keiji Kubo
Yoshiyuki Inada
Takehiko Naka
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE167861T1 publication Critical patent/ATE167861T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT93114754T 1992-09-14 1993-09-14 1,2,4-oxadiazolyl oder 1,2,4-thiadiazolyl- derivate als angiotensin ii antagonisten ATE167861T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP24530892 1992-09-14
JP34385592 1992-12-24

Publications (1)

Publication Number Publication Date
ATE167861T1 true ATE167861T1 (de) 1998-07-15

Family

ID=26537163

Family Applications (2)

Application Number Title Priority Date Filing Date
AT93114754T ATE167861T1 (de) 1992-09-14 1993-09-14 1,2,4-oxadiazolyl oder 1,2,4-thiadiazolyl- derivate als angiotensin ii antagonisten
AT97120618T ATE264323T1 (de) 1992-09-14 1993-09-14 Heterocyclische verbindungen und ihre verwendung als angiotensin ii antagonisten

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT97120618T ATE264323T1 (de) 1992-09-14 1993-09-14 Heterocyclische verbindungen und ihre verwendung als angiotensin ii antagonisten

Country Status (5)

Country Link
US (1) US5500427A (de)
EP (2) EP0588299B1 (de)
AT (2) ATE167861T1 (de)
CA (1) CA2106135A1 (de)
DE (2) DE69319391T2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2115985A1 (en) * 1993-02-25 1994-08-26 Kohei Nishikawa Vascular hypertrophy suppressor
JP3810020B2 (ja) 1993-04-22 2006-08-16 武田薬品工業株式会社 腎疾患の予防または治療剤
CZ154994A3 (en) * 1993-07-02 1995-09-13 Senju Pharma Co Visual hypotensive agent
GB9514160D0 (en) * 1994-07-25 1995-09-13 Zeneca Ltd Aromatic compounds
JPH10203981A (ja) * 1997-01-21 1998-08-04 Kureha Chem Ind Co Ltd 心疾患改善剤
US7812044B2 (en) 2001-11-13 2010-10-12 Takeda Pharmaceutical Company Limited Anticancer agents
US7232828B2 (en) * 2002-08-10 2007-06-19 Bethesda Pharmaceuticals, Inc. PPAR Ligands that do not cause fluid retention, edema or congestive heart failure
DK1841757T3 (da) * 2005-01-07 2010-09-13 Pfizer Prod Inc Heteroaromatiske quinolin-forbindelser og deres anvendelse som PDE10-hæmmere
WO2006094034A1 (en) 2005-03-01 2006-09-08 Wyeth Cinnoline compounds and their use as liver x receptor modilators
US8633175B2 (en) 2006-08-09 2014-01-21 Glaxosmithkline Llc Compounds as antagonists or inverse agonists at opioid receptors
TW200823204A (en) * 2006-10-17 2008-06-01 Arena Pharm Inc Biphenyl sulfonyl and phenyl-heteroaryl sulfonyl modulators of the histamine H3-receptor useful for the treatment of disorders related thereto
US20080207654A1 (en) * 2006-11-24 2008-08-28 Takeda Pharmaceutical Company Limited Heteromonocyclic compound and use thereof
US7803940B2 (en) * 2006-11-24 2010-09-28 Takeda Pharmaceutical Company Limited Heteromonocyclic compound or a salt thereof having strong antihypertensive action, insulin sensitizing activity and the like production thereof and use thereof for prophylaxis or treatment of cardiovascular diseases, metabolic diseases and/or central nervous system diseases
DE102017115778A1 (de) 2017-07-13 2019-01-17 Karl Storz Se & Co. Kg Medizinisches Instrument zum Abtragen von Gewebe
CN110143955B (zh) * 2018-02-11 2023-01-20 中国科学院上海药物研究所 含杂环侧链的噁二唑衍生物、合成方法及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5104891A (en) * 1989-12-11 1992-04-14 G. D. Searle & Co. Cycloheptimidazolone compounds as angiotensin ii antagonists for control of hypertension
EP0434038A1 (de) * 1989-12-22 1991-06-26 Takeda Chemical Industries, Ltd. Kondensierte Imidazolderivate, ihre Herstellung und Verwendung
IL99246A0 (en) * 1990-09-10 1992-07-15 Abbott Lab Angiotensin ii receptor antagonists and pharmaceutical compositions containing them
FR2673427B1 (fr) * 1991-03-01 1993-06-18 Sanofi Elf Derives heterocycliques diazotes n-substitues par un groupement biphenylmethyle, leur preparation, les compositions pharmaceutiques en contenant.
TW274551B (de) * 1991-04-16 1996-04-21 Takeda Pharm Industry Co Ltd
IL102183A (en) * 1991-06-27 1999-11-30 Takeda Chemical Industries Ltd The heterocyclic compounds are converted into biphenyl groups, their production and the pharmaceutical compositions containing them

Also Published As

Publication number Publication date
ATE264323T1 (de) 2004-04-15
DE69333489D1 (de) 2004-05-19
DE69319391T2 (de) 1998-10-29
US5500427A (en) 1996-03-19
DE69319391D1 (de) 1998-08-06
EP0588299A3 (en) 1994-06-01
EP0829479A1 (de) 1998-03-18
DE69333489T2 (de) 2005-04-14
EP0588299A2 (de) 1994-03-23
EP0829479B1 (de) 2004-04-14
CA2106135A1 (en) 1994-03-15
EP0588299B1 (de) 1998-07-01

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties