DE69333489D1 - Heterocyclische Verbindungen und ihre Verwendung als Angiotensin II Antagonisten - Google Patents

Heterocyclische Verbindungen und ihre Verwendung als Angiotensin II Antagonisten

Info

Publication number
DE69333489D1
DE69333489D1 DE69333489T DE69333489T DE69333489D1 DE 69333489 D1 DE69333489 D1 DE 69333489D1 DE 69333489 T DE69333489 T DE 69333489T DE 69333489 T DE69333489 T DE 69333489T DE 69333489 D1 DE69333489 D1 DE 69333489D1
Authority
DE
Germany
Prior art keywords
angiotensin
action
antagonists
heterocyclic compounds
diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69333489T
Other languages
English (en)
Other versions
DE69333489T2 (de
Inventor
Keiji Kubo
Yoshiyuki Inada
Takehiko Naka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE69333489D1 publication Critical patent/DE69333489D1/de
Publication of DE69333489T2 publication Critical patent/DE69333489T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69333489T 1992-09-14 1993-09-14 Heterocyclische Verbindungen und ihre Verwendung als Angiotensin II Antagonisten Expired - Fee Related DE69333489T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP24530892 1992-09-14
JP24530892 1992-09-14
JP34385592 1992-12-24
JP34385592 1992-12-24

Publications (2)

Publication Number Publication Date
DE69333489D1 true DE69333489D1 (de) 2004-05-19
DE69333489T2 DE69333489T2 (de) 2005-04-14

Family

ID=26537163

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69333489T Expired - Fee Related DE69333489T2 (de) 1992-09-14 1993-09-14 Heterocyclische Verbindungen und ihre Verwendung als Angiotensin II Antagonisten
DE69319391T Expired - Fee Related DE69319391T2 (de) 1992-09-14 1993-09-14 1,2,4-Oxadiazolyl oder 1,2,4-Thiadiazolyl-Derivate als Angiotensin II Antagonisten

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69319391T Expired - Fee Related DE69319391T2 (de) 1992-09-14 1993-09-14 1,2,4-Oxadiazolyl oder 1,2,4-Thiadiazolyl-Derivate als Angiotensin II Antagonisten

Country Status (5)

Country Link
US (1) US5500427A (de)
EP (2) EP0588299B1 (de)
AT (2) ATE264323T1 (de)
CA (1) CA2106135A1 (de)
DE (2) DE69333489T2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2115985A1 (en) * 1993-02-25 1994-08-26 Kohei Nishikawa Vascular hypertrophy suppressor
JP3810020B2 (ja) 1993-04-22 2006-08-16 武田薬品工業株式会社 腎疾患の予防または治療剤
CZ154994A3 (en) * 1993-07-02 1995-09-13 Senju Pharma Co Visual hypotensive agent
GB9514160D0 (en) * 1994-07-25 1995-09-13 Zeneca Ltd Aromatic compounds
JPH10203981A (ja) * 1997-01-21 1998-08-04 Kureha Chem Ind Co Ltd 心疾患改善剤
CA2466659A1 (en) 2001-11-13 2003-05-22 Takeda Chemical Industries, Ltd. Anticancer agents
US7232828B2 (en) 2002-08-10 2007-06-19 Bethesda Pharmaceuticals, Inc. PPAR Ligands that do not cause fluid retention, edema or congestive heart failure
ATE472543T1 (de) * 2005-01-07 2010-07-15 Pfizer Prod Inc Heteroaromatische chinolinverbindungen und deren verwendung als pde10-inhibitoren
US7700595B2 (en) 2005-03-01 2010-04-20 Wyeth Llc Cinnoline compounds
CN101522614B (zh) 2006-08-09 2014-06-25 史密丝克莱恩比彻姆公司 作为阿片样物质受体的拮抗剂或反向激动剂的化合物
TW200823204A (en) * 2006-10-17 2008-06-01 Arena Pharm Inc Biphenyl sulfonyl and phenyl-heteroaryl sulfonyl modulators of the histamine H3-receptor useful for the treatment of disorders related thereto
US7803940B2 (en) * 2006-11-24 2010-09-28 Takeda Pharmaceutical Company Limited Heteromonocyclic compound or a salt thereof having strong antihypertensive action, insulin sensitizing activity and the like production thereof and use thereof for prophylaxis or treatment of cardiovascular diseases, metabolic diseases and/or central nervous system diseases
AU2007322608A1 (en) 2006-11-24 2008-05-29 Takeda Pharmaceutical Company Limited Heteromonocyclic compound and use thereof
DE102017115778A1 (de) 2017-07-13 2019-01-17 Karl Storz Se & Co. Kg Medizinisches Instrument zum Abtragen von Gewebe
CN110143955B (zh) * 2018-02-11 2023-01-20 中国科学院上海药物研究所 含杂环侧链的噁二唑衍生物、合成方法及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5104891A (en) * 1989-12-11 1992-04-14 G. D. Searle & Co. Cycloheptimidazolone compounds as angiotensin ii antagonists for control of hypertension
EP0434038A1 (de) * 1989-12-22 1991-06-26 Takeda Chemical Industries, Ltd. Kondensierte Imidazolderivate, ihre Herstellung und Verwendung
IL99246A0 (en) * 1990-09-10 1992-07-15 Abbott Lab Angiotensin ii receptor antagonists and pharmaceutical compositions containing them
FR2673427B1 (fr) * 1991-03-01 1993-06-18 Sanofi Elf Derives heterocycliques diazotes n-substitues par un groupement biphenylmethyle, leur preparation, les compositions pharmaceutiques en contenant.
TW274551B (de) * 1991-04-16 1996-04-21 Takeda Pharm Industry Co Ltd
IL102183A (en) * 1991-06-27 1999-11-30 Takeda Chemical Industries Ltd The heterocyclic compounds are converted into biphenyl groups, their production and the pharmaceutical compositions containing them

Also Published As

Publication number Publication date
US5500427A (en) 1996-03-19
EP0829479A1 (de) 1998-03-18
DE69319391T2 (de) 1998-10-29
DE69333489T2 (de) 2005-04-14
EP0588299A2 (de) 1994-03-23
EP0588299B1 (de) 1998-07-01
EP0829479B1 (de) 2004-04-14
EP0588299A3 (en) 1994-06-01
CA2106135A1 (en) 1994-03-15
ATE167861T1 (de) 1998-07-15
ATE264323T1 (de) 2004-04-15
DE69319391D1 (de) 1998-08-06

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: TAKEDA PHARMACEUTICAL CO. LTD., OSAKA, JP

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee