CN101678059A - 含大麻素的植物提取物的新用途 - Google Patents

含大麻素的植物提取物的新用途 Download PDF

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Publication number
CN101678059A
CN101678059A CN200880016574A CN200880016574A CN101678059A CN 101678059 A CN101678059 A CN 101678059A CN 200880016574 A CN200880016574 A CN 200880016574A CN 200880016574 A CN200880016574 A CN 200880016574A CN 101678059 A CN101678059 A CN 101678059A
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Prior art keywords
cannabinoid
containing plant
channel
channels
cancer
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Chinese (zh)
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V·迪马佐
L·德佩特洛切利斯
A·夏诺莫里洛
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GW Pharma Ltd
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GW Pharma Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/348Cannabaceae
    • A61K36/3482Cannabis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
CN200880016574A 2007-04-19 2008-04-17 含大麻素的植物提取物的新用途 Pending CN101678059A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0707610.2 2007-04-19
GB0707610A GB2448535A (en) 2007-04-19 2007-04-19 New use for cannabinoid-containing plant extracts
PCT/GB2008/001359 WO2008129258A1 (en) 2007-04-19 2008-04-17 New use for cannabinoid-containing plant extracts

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CN101678059A true CN101678059A (zh) 2010-03-24

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CN200880016574A Pending CN101678059A (zh) 2007-04-19 2008-04-17 含大麻素的植物提取物的新用途

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US (1) US20100249223A1 (enExample)
EP (1) EP2146731B1 (enExample)
JP (1) JP5775300B2 (enExample)
CN (1) CN101678059A (enExample)
CA (1) CA2684562A1 (enExample)
ES (1) ES2717839T3 (enExample)
GB (1) GB2448535A (enExample)
WO (1) WO2008129258A1 (enExample)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102869356A (zh) * 2010-03-12 2013-01-09 Gw药品有限公司 治疗癌症中的植物大麻素
CN103533930A (zh) * 2011-05-20 2014-01-22 Gw药品有限公司 用于治疗神经性疼痛的大麻素类化合物
CN102083430B (zh) * 2008-06-04 2015-10-07 Gw药品有限公司 大麻类化合物组合物在制备治疗脑部肿瘤药物中的用途
CN105477635A (zh) * 2014-09-15 2016-04-13 中国人民解放军第二军医大学 一种治疗持续性慢性疼痛的靶点和药物
TWI577373B (zh) * 2011-09-29 2017-04-11 Gw伐瑪有限公司 包括植物大麻素次大麻二酚(cbdv)及大麻二酚(cbd)之藥學組成物
CN107846936A (zh) * 2015-07-22 2018-03-27 芙图法尔马国际有限公司 蜜蜂可摄取组成物及使用其生产蜂蜜的方法与由此生产的蜂蜜
CN108697665A (zh) * 2015-09-30 2018-10-23 乔治·爱德华·霍格 局部镇痛性疼痛缓解制剂、其制备和使用方法
CN109641022A (zh) * 2016-06-15 2019-04-16 奥海能量公益公司 用于减少氧化应激的方法和组合物
CN109939014A (zh) * 2017-12-20 2019-06-28 汉义生物科技(北京)有限公司 一种含有大麻素的口气清新剂
CN110913839A (zh) * 2017-05-22 2020-03-24 Gbs全球生物制药公司 靶向trpv1的含月桂烯和大麻素的组合物
CN112543633A (zh) * 2018-05-22 2021-03-23 Gbs全球生物制药公司 Trpv1调节中使用的大麻素和/或萜烯
CN115887440A (zh) * 2016-10-11 2023-04-04 Gbs全球生物制药公司 用于治疗神经退行性疾病的含有大麻素的复合混合物
CN119912407A (zh) * 2023-10-31 2025-05-02 北京红惠新医药科技有限公司 大麻二酚环氧化物的制备方法及应用

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008013861A2 (en) 2006-07-27 2008-01-31 Redpoint Bio Corporation Screening assay for inhibitors of trpa1 activation by a lower alkyl phenol
US9084771B2 (en) 2007-05-17 2015-07-21 Sutter West Bay Hospitals Methods and compositions for treating cancer
KR101063352B1 (ko) 2008-11-28 2011-09-07 고려대학교 산학협력단 Trpa1 활성 억제 약물 및 이의 활용
DE102010002558A1 (de) 2009-11-20 2011-06-01 Symrise Ag Verwendung physiologischer Kühlwirkstoffe und Mittel enthaltend solche Wirkstoffe
TWI583374B (zh) 2010-03-30 2017-05-21 Gw伐瑪有限公司 使用植物大麻素次大麻二酚(cbdv)來治療癲癇之用途
US8445034B1 (en) 2010-11-02 2013-05-21 Albert L Coles, Jr. Systems and methods for producing organic cannabis tincture
GB2487712B (en) 2011-01-04 2015-10-28 Otsuka Pharma Co Ltd Use of the phytocannabinoid cannabidiol (CBD) in combination with a standard anti-epileptic drug (SAED) in the treatment of epilepsy
JP6061448B2 (ja) * 2011-03-10 2017-01-18 株式会社マンダム 被験物質の評価方法
KR20120111125A (ko) * 2011-03-31 2012-10-10 주식회사한국전통의학연구소 마자인 추출물을 포함하는 신장암 치료용 조성물 및 건강 기능성 식품
GB2494461A (en) 2011-09-12 2013-03-13 Gw Pharma Ltd Phytocannabinoids for use in the treatment of invasive cancers or metastases
GB201117956D0 (en) * 2011-10-18 2011-11-30 Otsuka Pharma Co Ltd Phytocannabinoids for use in the treatment of breast cancer
US9776014B2 (en) 2012-05-03 2017-10-03 Magdent Ltd. Bone enhancement device and method
NL2009671C2 (en) * 2012-10-19 2014-04-23 Fytagoras B V New antiviral use for acidic cannabinoids.
GB2516814B (en) 2013-06-19 2016-08-31 Otsuka Pharma Co Ltd Use of phytocannabinoids for increasing radiosensitivity in the treatment of cancer
US10774288B2 (en) 2013-09-18 2020-09-15 The Werc Shop, LLC Terpene-based compositions, processes, methodologies for creation and products thereby
US9220294B2 (en) 2014-02-11 2015-12-29 Timothy McCullough Methods and devices using cannabis vapors
US10821240B2 (en) 2014-02-11 2020-11-03 Vapor Cartridge Technology Llc Methods and drug delivery devices using cannabis
US9380813B2 (en) 2014-02-11 2016-07-05 Timothy McCullough Drug delivery system and method
JP6673895B2 (ja) 2014-03-21 2020-03-25 エスティー アンド ティー インターナショナル,インコーポレイティド アサ属抽出方法及び組成物
US9044390B1 (en) 2014-04-17 2015-06-02 Gary J. Speier Pharmaceutical composition and method of manufacturing
US9186386B2 (en) 2014-04-17 2015-11-17 Gary J. Speier Pharmaceutical composition and method of manufacturing
GB2530001B (en) 2014-06-17 2019-01-16 Gw Pharma Ltd Use of cannabidiol in the reduction of convulsive seizure frequency in treatment-resistant epilepsy
GB2527599A (en) 2014-06-27 2015-12-30 Gw Pharma Ltd Use of 7-OH-Cannabidiol (7-OH-CBD) and/or 7-OH-Cannabidivarin (7-OH-CBDV) in the treatment of epilepsy
GB2527590A (en) * 2014-06-27 2015-12-30 Otsuka Pharma Co Ltd Active pharmaceutical ingredient (API) comprising cannabinoids for use in the treatment of cancer
GB2531282A (en) 2014-10-14 2016-04-20 Gw Pharma Ltd Use of cannabinoids in the treatment of epilepsy
GB2531278A (en) 2014-10-14 2016-04-20 Gw Pharma Ltd Use of cannabidiol in the treatment of intractable epilepsy
GB2531281A (en) 2014-10-14 2016-04-20 Gw Pharma Ltd Use of cannabidiol in the treatment of intractable epilepsy
BR122021018502B1 (pt) 2014-10-21 2022-05-03 United Cannabis Corp Formulação de canabinoide líquida
WO2016123475A1 (en) 2015-01-31 2016-08-04 Constance Therapeutics, Inc. Methods for preparation of cannabis oil extracts and compositions
US10238745B2 (en) 2015-01-31 2019-03-26 Constance Therapeutics, Inc. Cannabinoid composition and products including α-tocopherol
MX2017010872A (es) 2015-02-27 2018-05-07 Ebbu Llc Composiciones que comprenden combinaciones de cannabinoides purificados, con al menos uno de flavonoides, terpenos o minerales.
US10960035B2 (en) 2015-04-01 2021-03-30 The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Voleaui Center) Erodium crassifolium L'Her plant extracts and uses thereof
US12303541B2 (en) 2015-04-01 2025-05-20 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Erodium crassifolium L'Her plant extracts and uses thereof
GB2539472A (en) 2015-06-17 2016-12-21 Gw Res Ltd Use of cannabinoids in the treatment of epilepsy
GB2541191A (en) 2015-08-10 2017-02-15 Gw Pharma Ltd Use of cannabinoids in the treatment of epilepsy
GB2542797A (en) * 2015-09-29 2017-04-05 Gw Pharma Ltd Use of cannabinoids in the treatment of inflammatory skin diseases
WO2017091764A1 (en) 2015-11-24 2017-06-01 Constance Therapeutics, Inc. Cannabis oil compositions and methods for preparation thereof
GB2548873B (en) 2016-03-31 2020-12-02 Gw Res Ltd Use of Cannabidiol in the Treatment of SturgeWeber Syndrome
US10499584B2 (en) 2016-05-27 2019-12-10 New West Genetics Industrial hemp Cannabis cultivars and seeds with stable cannabinoid profiles
US10143706B2 (en) 2016-06-29 2018-12-04 Cannscience Innovations, Inc. Decarboxylated cannabis resins, uses thereof and methods of making same
GB2551987A (en) 2016-07-01 2018-01-10 Gw Res Ltd Oral cannabinoid formulations
GB2551986A (en) 2016-07-01 2018-01-10 Gw Res Ltd Parenteral formulations
GB2553139A (en) 2016-08-25 2018-02-28 Gw Res Ltd Use of cannabinoids in the treatment of multiple myeloma
US12485129B2 (en) 2016-08-29 2025-12-02 Canopy Growth Corporation Water soluble compositions comprising purified cannabinoids
CN110177543A (zh) 2016-08-29 2019-08-27 凯诺比生长公司 包含纯化大麻素的水溶性组合物
US10239808B1 (en) 2016-12-07 2019-03-26 Canopy Holdings, LLC Cannabis extracts
GB2557921A (en) 2016-12-16 2018-07-04 Gw Res Ltd Use of cannabinoids in the treatment of angelman syndrome
GB2559774B (en) 2017-02-17 2021-09-29 Gw Res Ltd Oral cannabinoid formulations
GB2560019A (en) 2017-02-27 2018-08-29 Gw Res Ltd Use of cannabinoids in the treatment of leukaemia
IL269158B2 (en) 2017-03-05 2024-04-01 The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization Aro Vo Cannabis compositions enriched in thca and their use in treating inflammatory diseases
GB2564383B (en) 2017-06-23 2021-04-21 Gw Res Ltd Use of cannabidiol in the treatment of tumours assoicated with Tuberous Sclerosis Complex
EP3675809B1 (de) 2017-08-31 2023-09-27 Basf Se Verwendung physiologischer kühlwirkstoffe und mittel enthaltend solche wirkstoffe
GB2568929A (en) 2017-12-01 2019-06-05 Gw Res Ltd Use of cannabinoids in the treatment of epilepsy
GB2569961B (en) 2018-01-03 2021-12-22 Gw Res Ltd Pharmaceutical
EP3745884A1 (en) 2018-01-31 2020-12-09 Canopy Holdings, Llc Hemp powder
JP2021521277A (ja) 2018-04-09 2021-08-26 エレヴェット・サイエンシズ 動物における疼痛の処置のためのアサ抽出物
WO2019222459A1 (en) * 2018-05-18 2019-11-21 Diverse Biotech, Inc. Cannabinoid preparations and therapeutic uses
CA3104795A1 (en) * 2018-06-28 2020-01-02 Canopy Growth Corporation Compositions and methods for agonizing the cb2 receptor
US11040932B2 (en) 2018-10-10 2021-06-22 Treehouse Biotech, Inc. Synthesis of cannabigerol
EP3968970A4 (en) * 2019-05-16 2023-01-25 Buzzelet Development And Technologies Ltd Local anesthetic comprising a trp channel modulator
WO2021055079A1 (en) 2019-09-16 2021-03-25 Vapor Cartridge Technology Llc Drug delivery system with stackable substrates
CN112569220B (zh) * 2019-09-30 2023-03-07 云南汉盟制药有限公司 四氢次大麻酚在制备用于治疗肺动脉高压药物中的应用及含有四氢次大麻酚的药物组合物
US12409131B2 (en) 2019-10-03 2025-09-09 Pike Therapeutics Usa, Inc. Transdermal delivery of dronabinol
US20210100737A1 (en) 2019-10-03 2021-04-08 Starton Therapeutics, Inc. Transdermal delivery of dronabinol
US12016829B2 (en) 2019-10-11 2024-06-25 Pike Therapeutics Inc. Pharmaceutical composition and method for treating seizure disorders
WO2021070120A1 (en) 2019-10-11 2021-04-15 Pike Therapeutics, Inc., 1219014 B.C. Ltd. Transdermal compositions comprising cannabidiol (cbd) for use in the treatment of seizure disorders
US12121617B2 (en) 2019-10-14 2024-10-22 Pike Therapeutics Inc. Transdermal delivery of cannabidiol
JP2022551730A (ja) 2019-10-14 2022-12-13 パイク セラピューティクス,インコーポレイテッド カンナビジオールの経皮送達
GB202002754D0 (en) 2020-02-27 2020-04-15 Gw Res Ltd Methods of treating tuberous sclerosis complex with cannabidiol and everolimus
WO2021188983A1 (en) * 2020-03-20 2021-09-23 The Queen's Medical Center Cannabinoid compositions
IL297546A (en) * 2020-04-24 2022-12-01 Zyus Life Sciences Inc Cannabichromene formulation for pain management
KR102433007B1 (ko) * 2020-07-28 2022-08-16 동의대학교 산학협력단 산골취 추출물을 포함하는 신경병증성 통증 예방 및 개선용 조성물
US11160757B1 (en) 2020-10-12 2021-11-02 GW Research Limited pH dependent release coated microparticle cannabinoid formulations
US12440454B2 (en) 2022-02-01 2025-10-14 Portland Technology Holdings Llc Pharmaceutical compositions containing hemp extract for administration to felines and related methods

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837228A (en) * 1979-05-31 1989-06-06 The University Of Mississippi Antiinflammatory and antimicrobial compounds and compositions
JPH0426622A (ja) * 1990-05-18 1992-01-29 Tsumura & Co 制癌剤
US5939429A (en) * 1997-09-30 1999-08-17 Virginia Commonwealth University Cardiovascular uses of cannabinoid compounds
GB9807639D0 (en) * 1998-04-14 1998-06-10 Kennedy Rheumatology Inst Anti-inflammatory agents
US6403126B1 (en) * 1999-05-26 2002-06-11 Websar Innovations Inc. Cannabinoid extraction method
US6949582B1 (en) * 1999-05-27 2005-09-27 Wallace Walter H Method of relieving analgesia and reducing inflamation using a cannabinoid delivery topical liniment
EP2298284A3 (en) * 2001-02-14 2013-12-18 GW Pharma Limited Mucoadhesive pharmaceutical formulations
US7025992B2 (en) * 2001-02-14 2006-04-11 Gw Pharma Limited Pharmaceutical formulations
GB2377633A (en) * 2001-05-11 2003-01-22 Gw Pharmaceuticals Ltd Pharmaceutical compositions comprising the cannabinoids THC and CBD
CH695661A5 (de) * 2001-03-06 2006-07-31 Forsch Hiscia Ver Fuer Krebsfo Pharmazeutische Zusammensetzung.
EP1497328A2 (en) * 2002-04-16 2005-01-19 Bayer HealthCare AG Regulation of human transient receptor potential channel
GB2394894B (en) * 2002-11-04 2005-08-31 G W Pharma Ltd New use for pharmaceutical composition
GB2414933B (en) * 2004-06-08 2009-07-15 Gw Pharma Ltd Cannabinoid compositions for the treatment of disease and/or symptoms in arthritis
GB2418612A (en) * 2004-10-01 2006-04-05 Gw Pharma Ltd Inhibition of tumour cell migration with cannabinoids
US7597910B2 (en) * 2005-08-20 2009-10-06 Slgm Medical Research Institute Compositions and methods for treating prostate disorders
JP2009513159A (ja) * 2005-10-31 2009-04-02 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Trpv2のモジュレーターを同定するための組成物および方法
GB2432312A (en) * 2005-11-01 2007-05-23 Gw Pharma Ltd Pharmaceutical compositions for the treatment of pain

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NAPLES, ITALY: "《www.cannabidiol.info》", 1 June 2006 *

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102083430B (zh) * 2008-06-04 2015-10-07 Gw药品有限公司 大麻类化合物组合物在制备治疗脑部肿瘤药物中的用途
CN102869356A (zh) * 2010-03-12 2013-01-09 Gw药品有限公司 治疗癌症中的植物大麻素
CN103533930A (zh) * 2011-05-20 2014-01-22 Gw药品有限公司 用于治疗神经性疼痛的大麻素类化合物
TWI577373B (zh) * 2011-09-29 2017-04-11 Gw伐瑪有限公司 包括植物大麻素次大麻二酚(cbdv)及大麻二酚(cbd)之藥學組成物
CN105477635A (zh) * 2014-09-15 2016-04-13 中国人民解放军第二军医大学 一种治疗持续性慢性疼痛的靶点和药物
US11426434B2 (en) 2015-07-22 2022-08-30 Phytopharma International Ltd. Bee-ingestible compositions, methods of using same for producing honey and honey produced thereby
CN107846936B (zh) * 2015-07-22 2021-06-01 芙图法尔马国际有限公司 蜜蜂可摄取组成物及使用其生产蜂蜜的方法与由此生产的蜂蜜
CN107846936A (zh) * 2015-07-22 2018-03-27 芙图法尔马国际有限公司 蜜蜂可摄取组成物及使用其生产蜂蜜的方法与由此生产的蜂蜜
CN108697665A (zh) * 2015-09-30 2018-10-23 乔治·爱德华·霍格 局部镇痛性疼痛缓解制剂、其制备和使用方法
CN109641022A (zh) * 2016-06-15 2019-04-16 奥海能量公益公司 用于减少氧化应激的方法和组合物
CN115887440A (zh) * 2016-10-11 2023-04-04 Gbs全球生物制药公司 用于治疗神经退行性疾病的含有大麻素的复合混合物
CN110913839A (zh) * 2017-05-22 2020-03-24 Gbs全球生物制药公司 靶向trpv1的含月桂烯和大麻素的组合物
US11944593B2 (en) 2017-05-22 2024-04-02 Gbs Global Biopharma, Inc. Myrcene-containing complex mixtures targeting TRPV1
CN109939014A (zh) * 2017-12-20 2019-06-28 汉义生物科技(北京)有限公司 一种含有大麻素的口气清新剂
CN112543633A (zh) * 2018-05-22 2021-03-23 Gbs全球生物制药公司 Trpv1调节中使用的大麻素和/或萜烯
CN119912407A (zh) * 2023-10-31 2025-05-02 北京红惠新医药科技有限公司 大麻二酚环氧化物的制备方法及应用

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Publication number Publication date
GB2448535A (en) 2008-10-22
ES2717839T3 (es) 2019-06-25
JP5775300B2 (ja) 2015-09-09
EP2146731A1 (en) 2010-01-27
GB0707610D0 (en) 2007-05-30
EP2146731B1 (en) 2019-01-16
CA2684562A1 (en) 2008-10-30
JP2010524912A (ja) 2010-07-22
US20100249223A1 (en) 2010-09-30
WO2008129258A1 (en) 2008-10-30

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