CN101652067A - 腺苷a2a受体拮抗剂 - Google Patents
腺苷a2a受体拮抗剂 Download PDFInfo
- Publication number
- CN101652067A CN101652067A CN200880010845A CN200880010845A CN101652067A CN 101652067 A CN101652067 A CN 101652067A CN 200880010845 A CN200880010845 A CN 200880010845A CN 200880010845 A CN200880010845 A CN 200880010845A CN 101652067 A CN101652067 A CN 101652067A
- Authority
- CN
- China
- Prior art keywords
- pyrrolo
- triazol
- furans
- ethyl
- pyrimidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 title abstract description 64
- 239000002126 C01EB10 - Adenosine Substances 0.000 title abstract description 32
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103261202A (zh) * | 2010-09-24 | 2013-08-21 | 阿迪维纳斯疗法有限公司 | 作为腺苷受体拮抗剂的稠合三环化合物 |
| CN109641911A (zh) * | 2016-08-19 | 2019-04-16 | 百时美施贵宝公司 | seco-环丙吡咯并吲哚化合物和其抗体-药物缀合物以及制备和使用方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2008000743A2 (en) * | 2006-06-27 | 2008-01-03 | Biovitrum Ab (Publ) | Novel 2',3'-methylidene acetyl adenosine prodrugs for use as prodrugs for adenosine receptor agonists |
| JP5748659B2 (ja) | 2008-06-10 | 2015-07-15 | アッヴィ・インコーポレイテッド | 新規な三環式化合物 |
| WO2010065668A1 (en) * | 2008-12-03 | 2010-06-10 | Presidio Pharmaceuticals, Inc. | Inhibitors of hcv ns5a |
| JP5765239B2 (ja) | 2009-03-13 | 2015-08-19 | アドヴィナス・セラピューティックス・リミテッド | 置換縮合ピリミジン化合物 |
| KR20120102724A (ko) | 2009-12-01 | 2012-09-18 | 아보트 러보러터리즈 | 신규한 트리사이클릭 화합물 |
| PE20121336A1 (es) * | 2009-12-01 | 2012-11-03 | Abbvie Inc | Nuevos compuestos triciclicos |
| WO2011101861A1 (en) | 2010-01-29 | 2011-08-25 | Msn Laboratories Limited | Process for preparation of dpp-iv inhibitors |
| WO2012149280A2 (en) * | 2011-04-29 | 2012-11-01 | Abbott Laboratories | Novel tricyclic compounds |
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- 2008-03-28 CN CN200880010845A patent/CN101652067A/zh active Pending
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| CN109641911A (zh) * | 2016-08-19 | 2019-04-16 | 百时美施贵宝公司 | seco-环丙吡咯并吲哚化合物和其抗体-药物缀合物以及制备和使用方法 |
| CN109641911B (zh) * | 2016-08-19 | 2023-02-21 | 百时美施贵宝公司 | seco-环丙吡咯并吲哚化合物和其抗体-药物缀合物以及制备和使用方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2129220A4 (en) | 2010-12-29 |
| NZ578720A (en) | 2011-01-28 |
| JP2010523497A (ja) | 2010-07-15 |
| AU2008232690A2 (en) | 2009-12-10 |
| MX2009010223A (es) | 2009-10-26 |
| WO2008121748A3 (en) | 2009-09-11 |
| IL201234A0 (en) | 2010-05-31 |
| EP2129220A2 (en) | 2009-12-09 |
| US7691869B2 (en) | 2010-04-06 |
| KR20100014397A (ko) | 2010-02-10 |
| CA2680075A1 (en) | 2008-10-09 |
| US20080242673A1 (en) | 2008-10-02 |
| US7723343B2 (en) | 2010-05-25 |
| AU2008232690A1 (en) | 2008-10-09 |
| US20080242672A1 (en) | 2008-10-02 |
| BRPI0808438A2 (pt) | 2014-07-29 |
| WO2008121748A2 (en) | 2008-10-09 |
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