CN101649354B - 核糖核苷酸标记核酸检测 - Google Patents

核糖核苷酸标记核酸检测 Download PDF

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Publication number
CN101649354B
CN101649354B CN200910203986.1A CN200910203986A CN101649354B CN 101649354 B CN101649354 B CN 101649354B CN 200910203986 A CN200910203986 A CN 200910203986A CN 101649354 B CN101649354 B CN 101649354B
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China
Prior art keywords
polynucleotide
nucleic acid
target nucleic
nucleotide
sequence
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English (en)
Chinese (zh)
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CN101649354A (zh
Inventor
K·A·鲍尔
D·H·盖尔芬德
I·G·古特
F·莫杰
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F Hoffmann La Roche AG
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
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F Hoffmann La Roche AG
Commissariat a lEnergie Atomique CEA
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN200910203986.1A 2008-04-21 2009-04-20 核糖核苷酸标记核酸检测 Active CN101649354B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US4672008P 2008-04-21 2008-04-21
US61/046720 2008-04-21
US12/421,188 US10150990B2 (en) 2008-04-21 2009-04-09 Ribonucleotide tag nucleic acid detection
US12/421188 2009-04-09

Publications (2)

Publication Number Publication Date
CN101649354A CN101649354A (zh) 2010-02-17
CN101649354B true CN101649354B (zh) 2015-04-29

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Family Applications (1)

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CN200910203986.1A Active CN101649354B (zh) 2008-04-21 2009-04-20 核糖核苷酸标记核酸检测

Country Status (6)

Country Link
US (2) US10150990B2 (https=)
EP (1) EP2112230B1 (https=)
JP (1) JP5483403B2 (https=)
CN (1) CN101649354B (https=)
CA (1) CA2663302C (https=)
ES (1) ES2392783T3 (https=)

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DE112013004650T5 (de) * 2012-09-24 2015-06-18 Cb Biotechnologies, Inc. Multiplexpyrosequenzierung unter Verwendung nichtinterferierender, rauschbeendender Polynukleotididentifikationstags
US10106842B2 (en) 2013-03-15 2018-10-23 Roche Molecular Systems, Inc. Nucleic acid target identification by structure based probe cleavage
US9828629B2 (en) 2013-03-15 2017-11-28 Roche Molecular Systems, Inc. Nucleic acid target identification by structure based probe cleavage
US9637791B2 (en) 2013-12-20 2017-05-02 Roche Molecular Systems, Inc. Multiplexed nucleic acid target identification by strucutre based probe cleavage
WO2016041591A1 (en) * 2014-09-17 2016-03-24 Roche Diagnostics Gmbh Nucleic acid target identification by structure based probe cleavage
US11034997B2 (en) 2016-09-15 2021-06-15 Roche Molecular Systems, Inc. Methods for performing multiplexed real-time PCR
WO2023212662A2 (en) * 2022-04-28 2023-11-02 Oregon Health & Science University Compositions and methods for modulating antigen binding activity

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Also Published As

Publication number Publication date
US20090263813A1 (en) 2009-10-22
EP2112230A3 (en) 2009-12-30
ES2392783T3 (es) 2012-12-13
CN101649354A (zh) 2010-02-17
US10150990B2 (en) 2018-12-11
US20130096027A1 (en) 2013-04-18
JP2009261392A (ja) 2009-11-12
EP2112230A2 (en) 2009-10-28
CA2663302C (en) 2014-09-09
EP2112230B1 (en) 2012-08-22
JP5483403B2 (ja) 2014-05-07
CA2663302A1 (en) 2009-10-21
HK1141559A1 (en) 2010-11-12

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