CN101631543B - 表面两性聚合物和低聚物的眼耳科组合物及其用途 - Google Patents

表面两性聚合物和低聚物的眼耳科组合物及其用途 Download PDF

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CN101631543B
CN101631543B CN2007800519191A CN200780051919A CN101631543B CN 101631543 B CN101631543 B CN 101631543B CN 2007800519191 A CN2007800519191 A CN 2007800519191A CN 200780051919 A CN200780051919 A CN 200780051919A CN 101631543 B CN101631543 B CN 101631543B
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polar
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CN101631543A (zh
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理查德·W·斯科特
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Polymedix Inc
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
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    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
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    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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CN2007800519191A 2006-12-29 2007-12-28 表面两性聚合物和低聚物的眼耳科组合物及其用途 Expired - Fee Related CN101631543B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88280006P 2006-12-29 2006-12-29
US60/882,800 2006-12-29
PCT/US2007/089001 WO2008083256A2 (en) 2006-12-29 2007-12-28 Ophthalmic and otic compositions of facially amphiphilic polymers and oligomers and uses thereof

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN2011103047415A Division CN102342941A (zh) 2006-12-29 2007-12-28 表面两性聚合物和低聚物的眼耳科组合物
CN201110305158.6A Division CN102600163B (zh) 2006-12-29 2007-12-28 表面两性聚合物和低聚物的眼耳科组合物

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CN101631543A CN101631543A (zh) 2010-01-20
CN101631543B true CN101631543B (zh) 2011-12-07

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CN2007800519191A Expired - Fee Related CN101631543B (zh) 2006-12-29 2007-12-28 表面两性聚合物和低聚物的眼耳科组合物及其用途
CN201110305158.6A Expired - Fee Related CN102600163B (zh) 2006-12-29 2007-12-28 表面两性聚合物和低聚物的眼耳科组合物
CN2011103047415A Pending CN102342941A (zh) 2006-12-29 2007-12-28 表面两性聚合物和低聚物的眼耳科组合物

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CN201110305158.6A Expired - Fee Related CN102600163B (zh) 2006-12-29 2007-12-28 表面两性聚合物和低聚物的眼耳科组合物
CN2011103047415A Pending CN102342941A (zh) 2006-12-29 2007-12-28 表面两性聚合物和低聚物的眼耳科组合物

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US (5) US20090092574A1 (https=)
EP (1) EP2114395B1 (https=)
JP (2) JP5512279B2 (https=)
CN (3) CN101631543B (https=)
AU (1) AU2007339790B2 (https=)
CA (1) CA2674080C (https=)
DK (1) DK2114395T3 (https=)
ES (1) ES2538479T3 (https=)
HU (1) HUE025868T2 (https=)
PL (1) PL2114395T3 (https=)
PT (1) PT2114395E (https=)
WO (1) WO2008083256A2 (https=)

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