CN101605768A - 螯合剂 - Google Patents

螯合剂 Download PDF

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Publication number
CN101605768A
CN101605768A CNA2007800452581A CN200780045258A CN101605768A CN 101605768 A CN101605768 A CN 101605768A CN A2007800452581 A CNA2007800452581 A CN A2007800452581A CN 200780045258 A CN200780045258 A CN 200780045258A CN 101605768 A CN101605768 A CN 101605768A
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CN
China
Prior art keywords
group
compound
methyl
compound according
carbonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2007800452581A
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English (en)
Chinese (zh)
Inventor
塞巴斯蒂安·诺尔
阿明·莫德林格
汉斯-于尔根·韦斯特
霍斯特·凯斯勒
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Technische Universitaet Muenchen
Original Assignee
Technische Universitaet Muenchen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technische Universitaet Muenchen filed Critical Technische Universitaet Muenchen
Publication of CN101605768A publication Critical patent/CN101605768A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CNA2007800452581A 2006-12-08 2007-12-10 螯合剂 Pending CN101605768A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0624587.2A GB0624587D0 (en) 2006-12-08 2006-12-08 Chelating agent
GB0624587.2 2006-12-08

Publications (1)

Publication Number Publication Date
CN101605768A true CN101605768A (zh) 2009-12-16

Family

ID=37711827

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2007800452581A Pending CN101605768A (zh) 2006-12-08 2007-12-10 螯合剂

Country Status (8)

Country Link
US (1) US20100081799A1 (enExample)
EP (1) EP2099776B1 (enExample)
JP (2) JP5705434B2 (enExample)
CN (1) CN101605768A (enExample)
CA (1) CA2671788A1 (enExample)
GB (1) GB0624587D0 (enExample)
IN (1) IN2009CN02681A (enExample)
WO (1) WO2008068516A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102898392A (zh) * 2012-09-06 2013-01-30 中国工程物理研究院核物理与化学研究所 N-乙酰氧苯基-3-[三叔丁氧甲酰基-四氮杂环十二烷基]中间体及其制备方法
CN104230832B (zh) * 2014-08-25 2018-07-27 曲靖师范学院 一种4，4’，4”，4”’-(1，4，7，10-四氮杂环十二烷-1，4，7，10-四基)四亚甲基四苯甲醛的合成方法

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0624587D0 (en) * 2006-12-08 2007-01-17 Univ Muenchen Tech Chelating agent
CN104307495A (zh) * 2014-10-14 2015-01-28 常州大学 一种含有四氮杂环的新型螯合树脂及其制备方法
EP4458418A3 (en) 2017-03-30 2024-11-13 Cornell University Macrocyclic complexes of alpha-emitting radionuclides and their use in targeted radiotherapy of cancer
BR112019023249A8 (pt) * 2017-05-05 2021-02-23 Centre For Probe Dev And Commercialization anticorpos monoclonais igf-1r e usos dos mesmos
US10093741B1 (en) 2017-05-05 2018-10-09 Fusion Pharmaceuticals Inc. IGF-1R monoclonal antibodies and uses thereof
IL270453B2 (en) 2017-05-05 2025-05-01 Fusion Pharmaceuticals Inc Pharmacokinetic enhancements of bifunctional chelates and uses thereof
KR102152939B1 (ko) * 2019-04-30 2020-09-07 한국화학연구원 공유결합성 트리아졸로 연결된 가시광선 흡수 광촉매, 이의 제조방법 및 이를 이용한 아자이드-알카인 고리화 첨가반응으로 트리아졸 유도체를 제조하는 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA894792B (en) * 1988-06-24 1991-04-24 Dow Chemical Co Macrocyclic bifunctional chelants,complexes thereof and their antibody conjugates
HU219485B (hu) * 1988-06-24 2001-04-28 Dow Chemical Co. Eljárás 1,4,7,10-tetraaza-ciklododekán-származékok, ezek komplexei, valamint antitestekkel képzett konjugátumai, és ilyeneket tartalmazó gyógyszerkészítmények előállítására és a komplexeket, illetve konjugátumokat tartalmazó diagnosztikai készítmények
US6093382A (en) * 1998-05-16 2000-07-25 Bracco Research Usa Inc. Metal complexes derivatized with folate for use in diagnostic and therapeutic applications
SI1603598T1 (sl) * 2003-03-19 2009-02-28 Universitaetsspital Basel Radiooznačeni konjugati na osnovi substance P innjihove uporabe
US20060155120A1 (en) * 2003-05-23 2006-07-13 Amedio John C Optically pure and enriched isomers of chelating ligands and contrast agents
CA2603847A1 (en) * 2005-04-08 2006-10-19 Cytogen Corporation Conjugated anti-psma antibodies
GB0624587D0 (en) * 2006-12-08 2007-01-17 Univ Muenchen Tech Chelating agent

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102898392A (zh) * 2012-09-06 2013-01-30 中国工程物理研究院核物理与化学研究所 N-乙酰氧苯基-3-[三叔丁氧甲酰基-四氮杂环十二烷基]中间体及其制备方法
CN102898392B (zh) * 2012-09-06 2015-08-12 中国工程物理研究院核物理与化学研究所 N-乙酰氧苄基-3-[-三叔丁氧甲酰基-四氮杂环十二烷基]中间体及其制备方法
CN104230832B (zh) * 2014-08-25 2018-07-27 曲靖师范学院 一种4，4’，4”，4”’-(1，4，7，10-四氮杂环十二烷-1，4，7，10-四基)四亚甲基四苯甲醛的合成方法

Also Published As

Publication number Publication date
GB0624587D0 (en) 2007-01-17
WO2008068516A1 (en) 2008-06-12
CA2671788A1 (en) 2008-06-12
JP5705434B2 (ja) 2015-04-22
US20100081799A1 (en) 2010-04-01
EP2099776A1 (en) 2009-09-16
JP2010511687A (ja) 2010-04-15
IN2009CN02681A (enExample) 2015-08-07
EP2099776B1 (en) 2015-10-07
JP2015155407A (ja) 2015-08-27

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Open date: 20091216