CN101595084B - 用于调整激酶级联的二芳基组合物和方法 - Google Patents

用于调整激酶级联的二芳基组合物和方法 Download PDF

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CN101595084B
CN101595084B CN200780031980XA CN200780031980A CN101595084B CN 101595084 B CN101595084 B CN 101595084B CN 200780031980X A CN200780031980X A CN 200780031980XA CN 200780031980 A CN200780031980 A CN 200780031980A CN 101595084 B CN101595084 B CN 101595084B
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alkyl
compound
compounds
aryl
kinase
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CN101595084A (zh
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小戴维·G·汉格尔
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Anzix Special Purpose Co ltd
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Kinex Pharmaceuticals LLC
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CN200780031980XA 2006-06-29 2007-06-29 用于调整激酶级联的二芳基组合物和方法 Active CN101595084B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11/480,174 US7968574B2 (en) 2004-12-28 2006-06-29 Biaryl compositions and methods for modulating a kinase cascade
US11/480,174 2006-06-29
US92349607P 2007-04-13 2007-04-13
US60/923,496 2007-04-13
PCT/US2007/015273 WO2008002676A2 (en) 2006-06-29 2007-06-29 Biaryl compositions and methods for modulating a kinase cascade

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CN101595084A CN101595084A (zh) 2009-12-02
CN101595084B true CN101595084B (zh) 2013-01-02

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US (3) US10196357B2 (enExample)
EP (1) EP2041071B1 (enExample)
JP (1) JP5564251B2 (enExample)
CN (1) CN101595084B (enExample)
AU (1) AU2007265373B2 (enExample)
CA (1) CA2656564C (enExample)
IL (1) IL196168A (enExample)
WO (1) WO2008127728A1 (enExample)

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US20100249130A1 (en) 2010-09-30
AU2007265373A1 (en) 2008-01-03
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IL196168A (en) 2015-11-30
US20190367456A1 (en) 2019-12-05
EP2041071B1 (en) 2014-06-18
EP2041071A2 (en) 2009-04-01
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