CN101573120B - 10-[(3r)-1-氮杂双环[2.2.2]辛烷-3-基甲基]-10h-吩噻嗪在制备选择性抑制m1、m2和m3型毒蕈碱受体的药物中的用途 - Google Patents

10-[(3r)-1-氮杂双环[2.2.2]辛烷-3-基甲基]-10h-吩噻嗪在制备选择性抑制m1、m2和m3型毒蕈碱受体的药物中的用途 Download PDF

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Publication number
CN101573120B
CN101573120B CN2007800467680A CN200780046768A CN101573120B CN 101573120 B CN101573120 B CN 101573120B CN 2007800467680 A CN2007800467680 A CN 2007800467680A CN 200780046768 A CN200780046768 A CN 200780046768A CN 101573120 B CN101573120 B CN 101573120B
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CN
China
Prior art keywords
incontinence
azabicyclo
phenothiazine
ylmethyl
purposes according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN2007800467680A
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English (en)
Chinese (zh)
Other versions
CN101573120A (zh
Inventor
T·克莱尔
J·蒂内-凡尔赛
C·普日贝尔斯基
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
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Pierre Fabre Medicament SA
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Publication date
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CN2007800467680A 2006-12-28 2007-12-26 10-[(3r)-1-氮杂双环[2.2.2]辛烷-3-基甲基]-10h-吩噻嗪在制备选择性抑制m1、m2和m3型毒蕈碱受体的药物中的用途 Expired - Fee Related CN101573120B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0656002 2006-12-28
FR0656002A FR2910814B1 (fr) 2006-12-28 2006-12-28 Utilisation du 10-°(r3)-1-azabicyclo°2.2.2!oct-3-ylmethyl!-10h- phenothiazine pour la preparation d'un medicament exercant une inhibition selective des recepteurs muscariniques m1,2,3
PCT/EP2007/064553 WO2008080924A1 (fr) 2006-12-28 2007-12-26 Utilisation du 10-[(3r)-1-azabicyclo[2.2.2]oct-3-ylméthyl]-10h-phénothiazine pour la préparation d'un médicament exerçant une inhibition sélective des récepteurs muscariniques m1, m2 et m3

Publications (2)

Publication Number Publication Date
CN101573120A CN101573120A (zh) 2009-11-04
CN101573120B true CN101573120B (zh) 2011-11-23

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN2007800467680A Expired - Fee Related CN101573120B (zh) 2006-12-28 2007-12-26 10-[(3r)-1-氮杂双环[2.2.2]辛烷-3-基甲基]-10h-吩噻嗪在制备选择性抑制m1、m2和m3型毒蕈碱受体的药物中的用途

Country Status (21)

Country Link
US (1) US8143245B2 (enExample)
EP (1) EP2124956A1 (enExample)
JP (1) JP5564263B2 (enExample)
KR (1) KR101465277B1 (enExample)
CN (1) CN101573120B (enExample)
AR (1) AR064714A1 (enExample)
AU (1) AU2007341274B2 (enExample)
BR (1) BRPI0720591A2 (enExample)
CA (1) CA2674162A1 (enExample)
FR (2) FR2910814B1 (enExample)
IL (1) IL199557A (enExample)
MA (1) MA31026B1 (enExample)
MX (1) MX2009006950A (enExample)
NO (1) NO20092654L (enExample)
NZ (1) NZ577915A (enExample)
RU (1) RU2449794C2 (enExample)
TN (1) TN2009000257A1 (enExample)
TW (1) TWI423806B (enExample)
UA (1) UA98131C2 (enExample)
WO (1) WO2008080924A1 (enExample)
ZA (1) ZA200904304B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015133989A (ja) * 2015-04-28 2015-07-27 重泉 達志 健康食品
KR101969263B1 (ko) 2018-07-16 2019-04-15 이상호 산소 챔버용 산소 공급 장치

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1173445B (it) * 1984-03-16 1987-06-24 Guidotti & C Spa Labor Agenti ad attivita' antibroncospastica e composizioni farmaceutiche che li contengono
IT1251161B (it) * 1991-08-07 1995-05-04 Derivati ammonio quaternari di (-) e (+)-3-(10 h-fenotiazin-10-ilmetil)-l-azabiciclo (2.2.2.)ottano e composizioni farmaceutiche che li contengono
AU6686700A (en) 1999-08-23 2001-03-19 H. Lundbeck A/S Treatment of urinary incontinence
AU2002366800B2 (en) * 2001-12-20 2006-08-03 Femmepharma Holding Company, Inc. Vaginal delivery of drugs

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Stanton T,et al.Antagonism of the five cloned human muscarinic cholinergic receptors expressed in CHO-K1 cells by antidepressants and antihistaminics.《Biochemical Pharmacology1993》.1993,第45卷(第11期),2352-2354. *

Also Published As

Publication number Publication date
US8143245B2 (en) 2012-03-27
JP2010514730A (ja) 2010-05-06
KR101465277B1 (ko) 2014-11-27
MX2009006950A (es) 2009-07-14
AR064714A1 (es) 2009-04-22
AU2007341274A1 (en) 2008-07-10
RU2009128326A (ru) 2011-02-10
JP5564263B2 (ja) 2014-07-30
RU2449794C2 (ru) 2012-05-10
FR2953721A1 (fr) 2011-06-17
AU2007341274B2 (en) 2012-09-20
HK1133207A1 (en) 2010-03-19
BRPI0720591A2 (pt) 2014-02-25
NZ577915A (en) 2011-12-22
CN101573120A (zh) 2009-11-04
TWI423806B (zh) 2014-01-21
UA98131C2 (ru) 2012-04-25
KR20090103887A (ko) 2009-10-01
TN2009000257A1 (fr) 2010-10-18
WO2008080924A1 (fr) 2008-07-10
NO20092654L (no) 2009-09-28
EP2124956A1 (fr) 2009-12-02
FR2910814B1 (fr) 2011-06-17
TW200833331A (en) 2008-08-16
FR2910814A1 (fr) 2008-07-04
ZA200904304B (en) 2010-06-30
CA2674162A1 (fr) 2008-07-10
US20100063276A1 (en) 2010-03-11
MA31026B1 (fr) 2009-12-01
IL199557A (en) 2014-09-30

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