CN101523217B - 基于ip-10的免疫学监测 - Google Patents

基于ip-10的免疫学监测 Download PDF

Info

Publication number
CN101523217B
CN101523217B CN200780032976.5A CN200780032976A CN101523217B CN 101523217 B CN101523217 B CN 101523217B CN 200780032976 A CN200780032976 A CN 200780032976A CN 101523217 B CN101523217 B CN 101523217B
Authority
CN
China
Prior art keywords
antigen
level
sample
test
infection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN200780032976.5A
Other languages
English (en)
Chinese (zh)
Other versions
CN101523217A (zh
Inventor
莫滕·鲁瓦尔德
佩妮莱·拉文
耶斯珀·欧金-奥尔森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Statens Serum Institut SSI
Original Assignee
Hvidovre Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hvidovre Hospital filed Critical Hvidovre Hospital
Publication of CN101523217A publication Critical patent/CN101523217A/zh
Application granted granted Critical
Publication of CN101523217B publication Critical patent/CN101523217B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56927—Chlamydia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/32—Mycobacterium
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01—DNA viruses
    • G01N2333/02—Hepadnaviridae, e.g. hepatitis B virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
    • G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
    • G01N2333/16—HIV-1, HIV-2
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/295—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Chlamydiales (o)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/35—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Mycobacteriaceae (F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/44—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from protozoa
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN200780032976.5A 2006-09-05 2007-09-05 基于ip-10的免疫学监测 Active CN101523217B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200601145 2006-09-05
DKPA200601145 2006-09-05
DKPA200700262 2007-02-20
DKPA200700262 2007-02-20
PCT/DK2007/000399 WO2008028489A2 (en) 2006-09-05 2007-09-05 Ip-i0 based immunological monitoring

Publications (2)

Publication Number Publication Date
CN101523217A CN101523217A (zh) 2009-09-02
CN101523217B true CN101523217B (zh) 2014-03-19

Family

ID=38716188

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200780032976.5A Active CN101523217B (zh) 2006-09-05 2007-09-05 基于ip-10的免疫学监测

Country Status (17)

Country Link
US (2) US8026076B2 (https=)
EP (4) EP2059816A2 (https=)
JP (1) JP5805368B2 (https=)
KR (1) KR101248491B1 (https=)
CN (1) CN101523217B (https=)
AT (1) ATE504000T1 (https=)
AU (1) AU2007294293B2 (https=)
BR (1) BRPI0714744B8 (https=)
CA (1) CA2662429C (https=)
DE (1) DE602007013620D1 (https=)
DK (2) DK2128612T3 (https=)
EA (1) EA020412B1 (https=)
IN (1) IN2015DN03125A (https=)
PL (1) PL2128612T3 (https=)
PT (1) PT2128612E (https=)
WO (1) WO2008028489A2 (https=)
ZA (1) ZA200902297B (https=)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0722105D0 (en) 2007-11-10 2007-12-19 Sec Dep For Environment Food A Antigens
WO2009158521A2 (en) * 2008-06-25 2009-12-30 Baylor Research Institute Blood transcriptional signature of mycobacterium tuberculosis infection
CN102105786B (zh) * 2008-07-25 2014-10-29 赛乐思迪斯有限公司 诊断方法
WO2010070581A1 (en) * 2008-12-15 2010-06-24 University Of Cape Town Method and device for diagnosing tuberculosis
GB0906215D0 (en) 2009-04-09 2009-05-20 Lalvani Ajit Diagnostic test
ES2413437T3 (es) * 2010-03-10 2013-07-16 Institut Pasteur HMGB1 y anticuerpos anti-HMGB1 en pacientes infectados por VIH especialmente con trastornos neurológicos
RU2012148779A (ru) * 2010-05-04 2014-06-10 Видоуре Хоспитал Увеличиваемое при помощи in vitro гипертермии иммунное распознавание
US20140087363A1 (en) * 2010-12-09 2014-03-27 Hvidovre Hospital Method for generating, storing, transporting, eluting and detecting clinical relevant information in plasma using filter paper
WO2012139591A1 (en) 2011-04-13 2012-10-18 Hvidovre Hospital Monitoring liver fibrosis in a hepatitis c infected patient
CN103619880A (zh) * 2011-04-29 2014-03-05 百时美施贵宝公司 Ip-10抗体剂量递增方法
CN103122033B (zh) * 2011-11-21 2015-08-19 厦门大学 一种嵌合重组抗原及其用途
EP2791679A1 (en) * 2011-12-15 2014-10-22 INSERM - Institut National de la Santé et de la Recherche Médicale Methods and kits for diagnosing latent tuberculosis infection
CN108802385B (zh) 2012-02-09 2022-02-08 米密德诊断学有限公司 用于诊断感染的标记和决定因素和其使用方法
WO2013168876A1 (ko) 2012-05-11 2013-11-14 가톨릭대학교 산학협력단 이식 후 면역 상태를 모니터링 하는 키트 및 이를 이용한 면역 상태의 모니터링 방법
JP6102438B2 (ja) 2012-05-30 2017-03-29 三菱化学株式会社 軸受部材、端部部材、感光体ドラムユニット、プロセスカートリッジ、及び軸受部材の製造方法
JP6020237B2 (ja) 2013-02-15 2016-11-02 三菱化学株式会社 軸受部材、端部部材、感光体ドラムユニット、及び軸受部材の製造方法
CA2923822A1 (en) 2013-09-10 2015-03-19 Immusant, Inc. Dosage of a gluten peptide composition
KR101542510B1 (ko) 2014-01-15 2015-08-18 대한민국 초기 hiv-1 감염자에서 급속한 aids 질환 진행을 예측하기 위한 ip-10의 용도
WO2015128830A1 (en) * 2014-02-26 2015-09-03 Stellenbosch University Method for diagnosing tuberculosis
KR101590324B1 (ko) * 2014-04-24 2016-02-01 연세대학교 산학협력단 향상된 결핵 진단 방법
AU2015249592A1 (en) * 2014-04-24 2016-12-15 Immusant, Inc. Use of Interleukin-2 for diagnosis of Celiac disease
BR112017002884A2 (pt) 2014-08-14 2018-01-30 Memed Diagnostics Ltd ?análise computacional de dados biológicos por meio do uso de variedade e hiperplano?
KR101748296B1 (ko) 2014-09-04 2017-06-19 연세대학교 산학협력단 마이코박테리움 압세수스 복합체 감염 폐질환 진단용 바이오마커 조성물
CA2962933A1 (en) 2014-09-29 2016-04-07 Immusant, Inc. Use of hla genetic status to assess or select treatment of celiac disease
AU2015349728A1 (en) 2014-11-21 2017-07-13 Immusant, Inc. Peptides for use in treatment and diagnosis of type 1 diabetes
CN107209184B (zh) 2014-12-11 2020-04-24 米密德诊断学有限公司 用于诊断多种感染的标记组合及其使用方法
CN104897893A (zh) * 2015-06-10 2015-09-09 复旦大学附属华山医院 一种基于结核特异性il-31检测的诊断结核分枝杆菌感染的试剂盒
EP3423590A4 (en) 2016-03-03 2020-02-26 Memed Diagnostics Ltd. DETERMINANTS OF RNA TO DIFFERENTIATE BACTERIAL VIRAL INFECTIONS
IL294121B2 (en) 2016-03-03 2023-09-01 Memed Diagnostics Ltd An RNA test to diagnose the type of infection
WO2018011796A1 (en) 2016-07-10 2018-01-18 Memed Diagnostics Ltd. Early diagnosis of infections
CA3027341A1 (en) 2016-07-10 2018-01-18 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
US11385241B2 (en) 2016-09-29 2022-07-12 Memed Diagnostics Ltd. Methods of prognosis and treatment
WO2018060999A1 (en) 2016-09-29 2018-04-05 Memed Diagnostics Ltd. Methods of risk assessment and disease classification
CN108548917B (zh) * 2018-03-01 2021-07-06 广州市雷德生物科技有限公司 一种记忆性免疫细胞的检测体系及其应用
US20220056528A1 (en) 2018-12-20 2022-02-24 Mikrogen Gmbh Method of detecting infection with pathogens causing tuberculosis
US20240026450A1 (en) 2020-06-19 2024-01-25 Mikrogen Gmbh Method of detecting infection with pathogens causing tuberculosis
WO2022169842A1 (en) * 2021-02-02 2022-08-11 Revelation Biosciences, Inc. Rapid detection kits and methods for diagnosing infections of the respiratory tract
WO2022240887A1 (en) * 2021-05-10 2022-11-17 Icahn School Of Medicine At Mount Sinai Methods for detecting and staging cellular viral immune responses

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005012907A1 (en) * 2003-08-01 2005-02-10 Renovar, Inc. Systems and methods for characterizing kidney diseases
CN1854287A (zh) * 2003-12-09 2006-11-01 亚洲基因科技股份有限公司 用于微生物检测分析系统、套组及方法
CN1866023A (zh) * 2006-05-25 2006-11-22 上海市肺科医院 一种同步检测多种结核杆菌特异性分泌抗原的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4777130A (en) * 1984-12-05 1988-10-11 Andra Biologicals Isolation of mycobacterial a 60 antigen for diagnostic purposes
JP5010079B2 (ja) * 1999-07-13 2012-08-29 スタテンズ セーラム インスティテュート マイコバクテリウム・ツベルクローシスｅｓａｔ−６遺伝子ファミリーベースの結核ワクチン及び診断法
AU2002214608A1 (en) * 2000-10-18 2002-04-29 The Government Of The United States Of America, As Represented By The Secretary Of The Navy A novel assay for detecting immune responses involving antigen specific cytokineand/or antigen specific cytokine secreting t-cells
US20040038201A1 (en) 2002-01-22 2004-02-26 Whitehead Institute For Biomedical Research Diagnostic and therapeutic applications for biomarkers of infection
WO2003063759A2 (en) * 2002-01-31 2003-08-07 Peptor Ltd. Hsp peptides and analogs for modulation of immune responses via antigen presenting cells
AU2002952548A0 (en) 2002-11-08 2002-11-21 Cellestis Limited Diagnostic assay
GB2427471B (en) 2004-03-04 2009-07-22 Laura Manuelidis Pre-symptomatic markers for diseases associated with transmissable spongiform encephalopaties
EP2253956A3 (en) * 2004-05-24 2011-07-06 Baylor Research Institute Immune response assessment method
US7332294B2 (en) * 2004-08-17 2008-02-19 University Health Network CXCL10-based diagnosis and treatment of respiratory illnesses
CA2478138A1 (en) 2004-08-17 2006-02-17 University Health Network Cxcl10-based diagnosis and treatment of respiratory illnesses
AU2006244151B2 (en) * 2005-05-05 2012-05-17 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods and compositions for detecting immune responses
EP1767937A1 (en) * 2005-09-27 2007-03-28 Institut National De La Sante Et De La Recherche Medicale (Inserm) Method of diagnosis of tuberculosis related immune restoration syndrome (IRS)
EP2441469A1 (en) * 2006-03-14 2012-04-18 Oregon Health and Science University Methods for producing an immune response to tuberculosis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005012907A1 (en) * 2003-08-01 2005-02-10 Renovar, Inc. Systems and methods for characterizing kidney diseases
CN1854287A (zh) * 2003-12-09 2006-11-01 亚洲基因科技股份有限公司 用于微生物检测分析系统、套组及方法
CN1866023A (zh) * 2006-05-25 2006-11-22 上海市肺科医院 一种同步检测多种结核杆菌特异性分泌抗原的方法

Also Published As

Publication number Publication date
WO2008028489A2 (en) 2008-03-13
EP2128612B1 (en) 2011-03-30
US20120015386A1 (en) 2012-01-19
US8026076B2 (en) 2011-09-27
EA200970246A1 (ru) 2009-10-30
CA2662429C (en) 2016-06-28
US20100086950A1 (en) 2010-04-08
CA2662429A1 (en) 2008-03-13
DK2128612T3 (da) 2011-07-18
BRPI0714744A8 (pt) 2016-04-05
EA020412B1 (ru) 2014-11-28
EP2228651A1 (en) 2010-09-15
EP2059816A2 (en) 2009-05-20
PT2128612E (pt) 2011-07-06
EP2261658A3 (en) 2011-05-11
IN2015DN03125A (https=) 2015-10-02
ATE504000T1 (de) 2011-04-15
KR101248491B1 (ko) 2013-04-03
DE602007013620D1 (de) 2011-05-12
CN101523217A (zh) 2009-09-02
PL2128612T3 (pl) 2011-09-30
EP2128612A2 (en) 2009-12-02
BRPI0714744A2 (pt) 2013-05-07
EP2261658B1 (en) 2015-01-28
DK2261658T3 (en) 2015-04-27
EP2128612A3 (en) 2009-12-09
KR20090074026A (ko) 2009-07-03
WO2008028489A3 (en) 2008-05-15
BRPI0714744B1 (pt) 2018-10-16
JP5805368B2 (ja) 2015-11-04
AU2007294293B2 (en) 2013-06-27
EP2261658A2 (en) 2010-12-15
BRPI0714744B8 (pt) 2021-07-27
ZA200902297B (en) 2015-10-28
JP2010502200A (ja) 2010-01-28
AU2007294293A1 (en) 2008-03-13

Similar Documents

Publication Publication Date Title
CN101523217B (zh) 基于ip-10的免疫学监测
Laing et al. A dynamic COVID-19 immune signature includes associations with poor prognosis
Goletti et al. Can we predict tuberculosis cure? What tools are available?
Al-Omari et al. Cytomegalovirus infection in immunocompetent critically ill adults: literature review
Corstjens et al. Multi-center evaluation of a user-friendly lateral flow assay to determine IP-10 and CCL4 levels in blood of TB and non-TB cases in Africa
AU2012244350B2 (en) Ip-10 based immunological monitoring
Stanton et al. Acute phase protein expression during elephant endotheliotropic herpesvirus-1 viremia in Asian elephants (Elephas maximus)
Chirathaworn et al. Cytokine levels as biomarkers for leptospirosis patients
US12566176B2 (en) Flow cytometry system and methods for the diagnosis of infectious disease
CN102246040A (zh) 用于诊断结核病的方法和装置
Lindsay et al. Laboratory diagnostics for Lyme disease
Skogstrand et al. Antigen-induced cytokine and chemokine release test for tuberculosis infection using adsorption of stimulated whole blood on filter paper and multiplex analysis
WO2008052566A1 (en) Ccl8 based immunological monitoring
US20140087363A1 (en) Method for generating, storing, transporting, eluting and detecting clinical relevant information in plasma using filter paper
WO2012167307A1 (en) Diagnosis of mycobacterial infection
CN119301450A (zh) 用于快速确定免疫状态的功能测定
Coughlin et al. Potential diagnostic biomarkers for pulmonary tuberculosis in humans are not elevated in Mycobacterium tuberculosis culture–positive Asian elephants (Elephas maximus)
ES2364173T3 (es) Control inmunológico basado en ip-10.
Akhvlediani et al. Comparison of total antibody and interferon-γ T-cell responses in patients following infection with brucellosis in Georgia
Kotzé Characterization of the innate and adaptive immune systems during active TB disease and during treatment
Essone Ndong Development of immune-based TB tests suitable for resource limited settings
EP2567230A1 (en) Hyperthermia augmented in-vitro immune recognition

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
ASS Succession or assignment of patent right

Owner name: STATENS SERUMINSTITUT;STATENS SERUMINSTITUT

Free format text: FORMER OWNER: HVIDOVRE HOSPITAL

Effective date: 20150609

C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20150609

Address after: Copenhagen

Patentee after: Statens Seruminstitut

Address before: Dane Harvey Dev

Patentee before: Hvidovre Hospital