CN101511861B - 抗炎和抗过敏的环肽 - Google Patents

抗炎和抗过敏的环肽 Download PDF

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Publication number
CN101511861B
CN101511861B CN2007800318987A CN200780031898A CN101511861B CN 101511861 B CN101511861 B CN 101511861B CN 2007800318987 A CN2007800318987 A CN 2007800318987A CN 200780031898 A CN200780031898 A CN 200780031898A CN 101511861 B CN101511861 B CN 101511861B
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CN
China
Prior art keywords
cys
lys
pro
ile
arg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2007800318987A
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English (en)
Chinese (zh)
Other versions
CN101511861A (zh
Inventor
莫尼卡·费雷拉
卡拉·希尔瓦
丹尼尔·皮曼塔
费尔南达·普尔塔罗
卡迪亚·康塞西奥
马里利恩·德马斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cristalia Produtos Quimicos e Farmaceuticos Ltda
Fundacao de Amparo a Pesquisa do Estado de Sao Paulo FAPESP
Original Assignee
Cristalia Produtos Quimicos e Farmaceuticos Ltda
Fundacao de Amparo a Pesquisa do Estado de Sao Paulo FAPESP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BRPI0703175A external-priority patent/BRPI0703175B8/pt
Application filed by Cristalia Produtos Quimicos e Farmaceuticos Ltda, Fundacao de Amparo a Pesquisa do Estado de Sao Paulo FAPESP filed Critical Cristalia Produtos Quimicos e Farmaceuticos Ltda
Priority claimed from PCT/BR2007/000186 external-priority patent/WO2008009085A1/en
Publication of CN101511861A publication Critical patent/CN101511861A/zh
Application granted granted Critical
Publication of CN101511861B publication Critical patent/CN101511861B/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/461—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from fish
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN2007800318987A 2006-07-21 2007-07-19 抗炎和抗过敏的环肽 Expired - Fee Related CN101511861B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
BRPI06028853 2006-07-21
BRPI0602885-3 2006-07-21
BRPI0602885 2006-07-21
BRPI0703175A BRPI0703175B8 (pt) 2007-07-04 2007-07-04 peptídeos cíclicos antiinflamatórios e antialérgicos
BRPI0703175-0 2007-07-04
BRPI07031750 2007-07-04
PCT/BR2007/000186 WO2008009085A1 (en) 2006-07-21 2007-07-19 Anti-inflammatory and antiallergic cyclic peptides

Publications (2)

Publication Number Publication Date
CN101511861A CN101511861A (zh) 2009-08-19
CN101511861B true CN101511861B (zh) 2013-04-24

Family

ID=41559284

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2007800318987A Expired - Fee Related CN101511861B (zh) 2006-07-21 2007-07-19 抗炎和抗过敏的环肽

Country Status (4)

Country Link
EP (1) EP2046815B1 (enExample)
JP (1) JP5635771B2 (enExample)
CN (1) CN101511861B (enExample)
MX (1) MX2009000800A (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102120755B (zh) * 2010-04-23 2013-04-03 江苏省人民医院 一种棕色脂肪组织靶向性多肽及其应用
JP5847418B2 (ja) 2011-03-30 2016-01-20 富士フイルム株式会社 細胞接着性タンパク質
CN117106028B (zh) * 2023-09-18 2024-02-13 首都医科大学附属北京朝阳医院 一种蛋白酶激活肽及其在制备预防和/或治疗心肌缺血/再灌注损伤的药物中的应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002016409A2 (en) * 2000-08-22 2002-02-28 Glaxosmithkline Biologicals S.A. Vaccine immunogens comprising disulphide bridged cyclised peptide and use thereof in the treatment of allergies
CA2487351A1 (en) * 2002-05-24 2003-12-04 Applied Nanosystems B.V. Export and modification of (poly)peptides in the lantibiotic way

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002016409A2 (en) * 2000-08-22 2002-02-28 Glaxosmithkline Biologicals S.A. Vaccine immunogens comprising disulphide bridged cyclised peptide and use thereof in the treatment of allergies
CA2487351A1 (en) * 2002-05-24 2003-12-04 Applied Nanosystems B.V. Export and modification of (poly)peptides in the lantibiotic way

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
G.S.Magalhāes et al.Natterins, a new class of proteins with kininogenase activity characterized from Thalassophryne nattereri fish venom.《Biochimie》.2005,第87卷第687-699页. *
G.S.Magalhāesetal.Natterins a new class of proteins with kininogenase activity characterized from Thalassophryne nattereri fish venom.《Biochimie》.2005

Also Published As

Publication number Publication date
MX2009000800A (es) 2009-04-16
CN101511861A (zh) 2009-08-19
JP2010503613A (ja) 2010-02-04
EP2046815A1 (en) 2009-04-15
EP2046815B1 (en) 2012-08-08
EP2046815A4 (en) 2010-09-22
JP5635771B2 (ja) 2014-12-03
HK1135406A1 (en) 2010-06-04

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