CN101496575A - Special nutrient foodstuffs formula containing small peptide and probiotics - Google Patents
Special nutrient foodstuffs formula containing small peptide and probiotics Download PDFInfo
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- CN101496575A CN101496575A CNA2008100066022A CN200810006602A CN101496575A CN 101496575 A CN101496575 A CN 101496575A CN A2008100066022 A CNA2008100066022 A CN A2008100066022A CN 200810006602 A CN200810006602 A CN 200810006602A CN 101496575 A CN101496575 A CN 101496575A
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- small peptide
- bifidobacterium
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Abstract
The invention provides a special nutrition food formulation containing short peptide and probiotic. The food formulation uses food-originated short peptide as a raw material which is added with the probiotic and functional oligosaccharide to form a compound formulation. With the formulation, dry powder foods can be prepared and are taken with cooled water. The foods prepared according to the formulation can improve the nutritional status of organism proteins, optimize the micro-ecological environment in intestines, regulate the functions of intestinal tracts, prevent constipation, diarrhea and colon cancer, enhance the immunity, whiten skins, and strengthen the physique comprehensively.
Description
Technical field:
The present invention relates to a kind of food formula, especially relate to and a kind ofly can replenish protein, can improve the body protein nutrition condition, regulate the gut flora balance, keep the special nutrient foodstuffs formula of enteron aisle normal function.
Background technology:
Guarantee needed by human nutrition, keep intestinal health, be the basis of health, and be subjected to extensive concern and attention.The function of intestinal canal disorder as constipation, diarrhoea, not only causes the discomfort of health, also can cause other more disease.With the constipation is example, and on medical science, constipation is obstructed, or ight soil overstays in enteron aisle (above 48 hours), causes fecal water content obviously to reduce, and excrement matter is stiff, and often 3～5 days or the longer time row phenomenon of stool once are constipation.Constipation for a long time causes the gut flora disorder, produces harmful substances such as a large amount of indoles, ammonia, formaldehyde, hydrogen sulfide in the body, causes dry skin, gloomy on the one hand, and skin of face is president's acne, living sore also, blackspot, freckle, age mark occur, influences aesthetic feeling; These refuses are absorbed into blood in a large number on the other hand, have not only increased the metabolism burden of liver, also can influence the normal thinking activities of brain, moreover also can bring out the outbreak of diseases such as angina pectoris, miocardial infarction, cerebral hemorrhage because of defecation firmly.In addition, because the harmful intestinal tract material that constipation produces is easy to cause cell carcinogenesis to the long pessimal stimulation of intestines wall mucomembranous cell, form colon cancer.Therefore, normal function of intestinal canal is the prerequisite of health.Have healthy enteron aisle, also just had health.
The function of intestinal canal of human body is subjected to the influence of micro-ecological environment in the enteron aisle to a great extent.Microbe species in the enteron aisle is a lot, but can be divided into two classes substantially.One class is probio such as Bifidobacterium, the lactobacillus acidophilus etc. that are of value to health, and another kind of is to produce the spoilage organisms of various harmful substances such as Escherichia coli etc.Spoilage organisms increases, and harmful substances such as the indoles of generation, ammonia, formaldehyde, hydrogen sulfide increase, and can cause function of intestinal canal inharmonious, can cause the body discomfort.Probio is to keep important organic factor healthy in the intestines.Scientific research confirms, increases quantity and the ratio of probio in the intestines, can effectively suppress the growth of spoilage organisms, improves function of intestinal canal, improves health.
The growth of probio also is subjected to influence of various factors with breeding in the intestines.Functional oligose class material is important beneficial bacteria factor, can effectively promote probio propagation, promotes intestines wall wriggling, is the important substance of improving function of intestinal canal.
Along with the development of biological enzymolysis engineering, find middle the catabolite of protein---eat source property small peptide, be not only and be easy to the nitrogenous source that utilized by body, also have multiple physiological regulation function, obviously be better than complete protein.In addition, food source property small peptide also has material impact to probio growth and breeding in the intestines.
Improving aspect the function of intestinal canal, have in the market and utilize compound sugar (as xylo-oligosaccharide, FOS) development product merely, the product that utilizes probio (as lactic acid bacteria, Bifidobacterium) preparation is merely arranged, also have utilize probio, compound sugar, again in conjunction with the report (patent No. 200710099425.2 " a kind of nutrition albumen powder that contains profitable probliotics ") of complete protein (as lactalbumin) development.But patent documentation and non-patent literature there is no identical with claim of the present invention with food source property small peptide be primary raw material, simultaneously add probio and compound sugar, be used to improve the record of the food of special nutrients of function of intestinal canal.
Summary of the invention:
The objective of the invention is to develop a kind of prescription that adopts the food of special nutrients that contains small peptide and probio that food source property small peptide, probio, compound sugar be mixed and processed.This invention prescription passes through the mentioned component organic assembling, can be that body replenishes the protein that very easily absorbs and utilize, and optimizes micro-ecological environment in the intestines, keeps health in the intestines, the improvement of invigorating health effectively.
The food of special nutrients that the present invention proposes is to be primary raw material with the small peptide, adds probio, compound sugar again, the compound prescription that is combined into.
The main component of the present invention's prescription is:
Food source property small peptide:
Food source property small peptide also claims oligopeptide, is meant the small protein that utilizes biological enzymolysis technology separation and Extraction from animal/vegetable protein.It is to be made of 2～6 amino acid basically, and molecular weight is below 1000Dalton.Food source property small peptide is soluble in water, can directly absorb without digestion, has very high bioavailability, all is better than amino acid and complete protein in absorption and utilization, can be applicable in the protein supplement, and be the nitrogenous source of human body high-quality.
Food source property small peptide has the important physical function in body:
1) trophism.Food source property small peptide molecular weight is little, can directly absorb without digestion, and the absorption process power consumption is low, speed is fast, and warfare and height when not existing free amino acid to absorb ooze phenomenon.Simultaneously, the food source property small peptide in multiple source cooperatively interacts and is easier to realize the balance of essential amino acid, is easier to improve the bioavailability of body.Therefore, from the angle of nutrition, small peptide is better than free amino acid.
2) improve intestinal absorption ability.Zoopery shows, food source property small peptide can promote the growth and the differentiation of intestinal epithelial cell, increase the protein content of mucous membrane of small intestine, increase the activity of aminopeptidase, can increase the height and the surface area of intestinal villi, deepen the degree of depth of crypts, stimulate the growth of intestinal glands, improve the digestion and the absorption function of small intestine.
3) absorption of mineral matters such as promotion calcium, iron, zinc.Food source property small peptide can form chelate with calcium, iron, zinc etc., changes mineral matter element with the form of carrier and shifts by mucous membrane of small intestine, has improved the absorptivity of mineral matter.
5) improve immunity.There are some researches show, the carbon that small peptide can improve mouse cleans up ability, improve mouse macrophage engulfs the chicken red blood cell phagocytic rate, improves mouse macrophage and engulf the chicken red blood cell phagocytic index, improve mouse the delayed allergy ability, strengthen the mouse lymphocyte conversion capability that ConA induces.Can improve the immunity of body, improve the resistance level of body.
6) anti-oxidant, radiation-resisting functional.Zoopery and human experimentation all confirm, food source property small peptide can increase the activity of serum superoxide dismutases (SOD), glutathione peroxidase (GSH-PX), catalase (CAT), reduce the concentration of serum lipid peroxide MDA (MDA), has tangible anti-oxidation function, can remove interior free yl, simultaneously, food source property small peptide has stronger radioresistance activity, can delaying skin and the aging of other tissue.
7) regulate functions such as blood sugar, blood fat, blood pressure.Food source property small peptide can auxiliary hyperglycemic, auxiliary antilipemic, aided blood pressure-lowering, and under higher dosage, time situation more of a specified duration, effect more obviously.
8) food source property small peptide is easy to be utilized by life entity, can effectively promote the growth and the propagation of beneficial bacteria of intestinal tract.
Small peptide of the present invention is meant marine collagen peptide, Soyprotein peptide, whey protein peptide, wherein a kind of, several or whole mixing of ovalbumin peptide.
Marine collagen peptide of the present invention is meant that the fish-skin with deep-sea fish (as salmon etc.) is a raw material, utilizes biological enzymolysis technology, the small protein of extraction, and its mean molecule quantity is lower than 1000Dalton.
Sea bone peptide of the present invention is meant that the fish-bone with deep-sea fish (as cod, anglerfish etc.) is a raw material, utilizes biological enzymolysis technology, the small protein of extraction, and its mean molecule quantity is lower than 1000Dalton.
It is raw material that Soyprotein peptide of the present invention is meant with the soybean protein, utilizes biological enzymolysis technology, the small protein of extraction, and its mean molecule quantity is lower than 1000Dalton.
Whey protein peptide of the present invention is meant that the lactalbumin with cow's milk is a raw material, utilizes biological enzymolysis technology, the small protein of extraction, and its mean molecule quantity is lower than 1000Dalton.
Ovalbumin peptide of the present invention is meant that with egg protein (as egg albumen) be raw material, utilizes biological enzymolysis technology, the small protein of extraction, and its mean molecule quantity is lower than 1000Dalton.
Probio:
Probio of the present invention is meant the microorganism of the work that is present in occurring in nature, when taking in liberal quantity, by improving the gut flora balance human body is produced wholesome effect.Probio reduces with advancing age gradually in the human body intestinal canal, thereby causes disorderly or other physiological change of function of intestinal canal.
The present invention by probiotic supplemented and promote probio growth and breeding can, to realize following physiological function:
1) suppresses the spoilage organisms growth.Bifidobacterium increases in the intestines, can produce a large amount of rudimentary organic acids, and the acid-base value of enteron aisle is reduced, and effectively suppresses the growth and breeding of spoilage organisms (as enterobacteria, clostridium etc.) in the intestines.Reduce the generation of intestines intracellular metabolite refuse such as ammonia, phenol, hydrogen sulfide, indoles etc. thus.
2) form microbial barrier.The propagation of Bifidobacterium can form the isolation strip at intestinal contents between colon wall, can effectively stop contacting of intestinal toxic material and intestines wall, reduces the absorption of harmful substance.
3) synthetic vitamin and amino acid improve immunity.Bifidobacterium is synthesized multiple B family vitamin (B
1, B
2, B
6, nicotinic acid, folic acid etc.) and vitamin K etc., the bifidobacterium cells that every gram is done contains Cobastab
1100mg, Cobastab
22.5mg.This is that human body absorbs in food the external source vitamin, mainly rely on Bifidobacterium synthetic provide vitamin.Bifidobacterium can also suppress to decompose the growth of thiamine bacillus, prevents Cobastab
1Loss.But it also synthesizing amino acids material utilized by intestinal absorption, improve immunity.Bifidobacterium can also strengthen the generation of igA antibody, and the activating macrophage activate the phagocytic capacity improves the body resistance infection, prevention, inhibition and kill tumor cell.
4) anti-cancer and anticancer, protection liver.Ight soil holdup time in intestines is long, and there are certain carcinogenesis in spoilage organisms generation corrupt substance such as ammonia, hydrogen sulfide, indoles, nitrosamine, endotoxin in the intestines, bring out colon cancer easily.After these materials are entered blood by the body absorption simultaneously, need detoxify, increase burden of liver by liver.Untimely if detoxify, can cause dizziness, weak, insomnia, pigment deposition, bring out diseases such as senile dementia, endanger healthy.
The probio of adding in the present invention's prescription comprises a kind of, several or whole mixing wherein of lactobacillus acidophilus, Lactobacillus casei, Lactobacillus Jensenii, Raman lactobacillus, bifidobacterium longum, bifidobacterium breve, avette Bifidobacterium, bifidobacterium thermophilum, bifidobacterium lactis.
Compound sugar:
Compound sugar claims oligosaccharides again, is meant the low polymerization sugar of the straight or branched that is connected to form by glycosidic bond by 2～10 monose.Functional oligose is not absorbed by human consumption, is not utilized by most enteron aisle spoilage organisms yet, but can promote beneficial bacteria---the growth and breeding of Bifidobacterium in the human body, suppresses the spoilage organisms growth, helps to improve and keep the enteron aisle normal function.Compound sugar can also stimulate intestines wall wriggling, quickens the discharge of swill in the intestines, the prevention constipation.Long-term edible can delay senility, defaecation, raising immunity, alleviate burden of liver, improve the nutrient absorption rate, particularly can improve the absorption of body calcium, iron, zinc ion.
Compound sugar of the present invention is a kind of, several or whole mixing wherein of oligoisomaltose, FOS, soyabean oligosaccharides, xylo-oligosaccharide.
Above-mentioned various batch mixes is even, through super-dry, makes powdered food; Or, make granule state food through specific embedding process.
The technological merit of the present invention's prescription:
The present invention will eat source property small peptide, probio, compound sugar and cooperate prescription, can effectively bring into play the effect of various compositions, and help utilizing the synergy between each composition, effectively improve body protein nutrition condition and function of intestinal canal.
The characteristic of this formula food and the effect of body mainly shown the following aspects:
1. replenish small peptide, realize nutrition improvement.Be to be that body replenishes protein with small peptide in the present invention prescription, be easy to absorb as nitrogenous source.Small peptide helps keeping the integrality and the normal function of intestines wall mucous membrane, improves the absorption function of small intestine, and small peptide can promote the transhipment and the absorption of mineral matter, therefore, helps the improvement of body nutrition condition.
2. improve micro-ecological environment in the intestines.The present invention fills a prescription and directly replenishes the probio useful to body, and promote growth and the breeding of probio by compound sugar and small peptide, and increase the absolute quantity of beneficial bacteria of intestinal tract, suppress the growth and breeding of spoilage organisms, optimize micro-ecological environment in the intestines, keep normal function of intestinal canal.
3. prevention constipation.Formula food of the present invention can stimulate intestines peristalsis, promotes that refuse is discharged in the intestines, improves the constipation situation.
4. protection liver, pre-anti-cancer.Formula food of the present invention promotes the discharge of harmful substance by reducing the generation of poisonous and harmful substance, has reduced the absorption of harmful substance.And then effectively alleviating burden of liver, the prevention colon cancer takes place.
5. enhancing immunity.By the double action of probio and small peptide, improve the immune level of body, strengthen resistance against diseases.
6. skin whitening.Long-term edible, help strengthening skin elasticity, keep moisture of skin, reach cosmetic result.
7. long-term edible, can help body anti-oxidant, delay senility, realize regulating action to blood sugar, blood pressure, blood fat etc.
The specific embodiment:
The invention will be further described by the following examples.
Embodiment 1 preparation is for the edible peptide benefit bacterium powder food (powdery) of constipation patient
Present embodiment is selected marine collagen peptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide, bifidobacterium lactis, lactobacillus acidophilus, isomalto-oligosaccharide, the xylo-oligosaccharide of powdery, fills a prescription by following raw material and consumption thereof.
Marine collagen peptide 2.0g sea bone peptide 0.5g Soyprotein peptide 0.5g whey protein peptide 1.0g ovalbumin peptide 0.5g
Bifidobacterium lactis 0.2g lactobacillus acidophilus 0.1g
Isomalto-oligosaccharide 2.0g xylo-oligosaccharide 0.2g
Above-mentioned raw materials is mixed, drying, sealing promptly can be made into.Take after mixing it with water with a certain amount of cold water.
Embodiment 2 preparation beauty foods-peptide benefit bacterium powder food (powdery)
Present embodiment is selected marine collagen peptide, lactobacillus acidophilus and the isomalto-oligosaccharide of powdery, fills a prescription by following raw material and consumption thereof.
Marine collagen peptide 4.0g
Lactobacillus acidophilus 0.5g
Isomalto-oligosaccharide 3.5g
Above-mentioned raw materials is mixed, drying, sealing promptly can be made into.Take after mixing it with water with a certain amount of cold water.
Claims (5)
1. a special nutrient foodstuffs formula that contains small peptide and probio is characterized in that with the small peptide being primary raw material, adds probio, functional oligose again, forms compound prescription.
2. the special nutrient foodstuffs formula that contains small peptide and probio according to claim 1, it is characterized in that described small peptide is oligopeptide, be meant a kind of, several or whole mixing wherein of marine collagen peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide.
3. the special nutrient foodstuffs formula that contains small peptide and probio according to claim 1 is characterized in that described probio is meant a kind of, several or whole mixing wherein of lactobacillus acidophilus, Lactobacillus casei, Lactobacillus Jensenii, Raman lactobacillus, bifidobacterium longum, bifidobacterium breve, avette Bifidobacterium, bifidobacterium thermophilum, bifidobacterium lactis.
4. the special nutrient foodstuffs formula that contains small peptide and probio according to claim 1 is characterized in that described functional oligose is a kind of, several or whole mixing wherein of oligoisomaltose, FOS, soyabean oligosaccharides, xylo-oligosaccharide.
5. the special nutrient foodstuffs formula that contains small peptide and probio according to claim 1 is characterized in that being mixed with powdering or granule state food according to described prescription.
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Address after: 100015 Beijing, Jiuxianqiao Middle Road, building 24, No., building 6 Patentee after: China National Academy of Food & Fermentation Industries Patentee after: Sino Peptide (Beijing) Healthy Technology Co., Ltd. Address before: 100027 Beijing city Chaoyang District Xiaoyun Road No. 32 Patentee before: China National Academy of Food & Fermentation Industries Patentee before: Sino Peptide (Beijing) Healthy Technology Co., Ltd. |