JP2001224330A - Food comprising lactobacillus symbiotic culture product and medicinal plant and method for producing the same - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a health food exerting synergistic effect and health maintenance effect each afforded by lactobacillus symbiotic culture products and root stocks, leaves or flowers of medicinal plants such as turmeric, Orthosiphon stamineus, hibiscus, guava, ginkgo and loquat. SOLUTION: This health food comprises at least one kind of medicinal plants such as turmeric, Orthosiphon stamineus, hibiscus, guava, ginkgo, Peucedanum japonicum Thumb, Houttuynia cordata and loquat leaves.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD [0001] The present invention relates to a health food for promoting and maintaining health, comprising a combination of a lactic acid bacteria co-cultivation culture with turmeric and other herbs.

[0002]

2. Description of the Related Art Normally, when it comes to health from the viewpoint of living body health, it is easy to think of ingesting nutrient-rich foods immediately, but each organ of the digestive system, such as the stomach and intestines, is nourished. If you lose the normal and healthy ability to digest and absorb the food, the food you take in is unnecessary for the body, ie, spoilage bacteria (welsh bacteria), amines, indole, mercaptan, ammonia, hydrogen sulfide, etc. Changes to harmful substances such as toxic gases. Therefore, this harmful substance accumulates in the body and damages normal cells. As a result, the function of tissues and organs is adversely affected, thereby causing an aging phenomenon. Therefore, in order to maintain and promote health, it is indispensable to suppress the aging phenomenon of the living body as much as possible, to vitalize all cells in the body, and to make the digestive organs of the stomach and intestines healthy and normal.

As lactic acid bacteria-related foods, living lactic acid bacteria such as yogurt, that is, foods using live bacteria are mostly used. For example, Bulgaria bacteria and yogurt bacteria belonging to the genus Lactobacillus are used as live cells and live cells. It was a conventional usage. However, it has been pointed out that the Bulgarian bacterium is ineffective in maintaining intestinal health because it has been found that it does not inhabit the intestine. Lactic acid bacteria, in addition to consuming large amounts of carbohydrates, are necessary for fermenting lactose.
It has been confirmed to be present in animal tissues. Thus, a bacterium that produces an acid or lactic acid by the action of lactose is a lactic acid bacterium.

[0004] Lactic acid bacteria are said to be non-pathogenic except for a few species of Streptococcus that generally grow on animal parasites or adhere to plants. Such lactic acid bacteria are microorganisms that strongly act on sugar during lactic acid fermentation and lactic acid ferment the sugar, so they are known as beneficial bacteria together with yeast, and health foods and cheese made from these live bacteria are used as raw materials. Lactic beverages such as butter, yogurt, etc. are being developed. However, foods using such live cells,
It is said that even if ingested by humans, the fungi contained therein are killed before reaching the intestine due to bile and stomach acid, etc., and therefore, it is said that health effects cannot be expected. On the other hand, it is known that the intracellular components and extracellular secretions of lactic acid bacteria completely reach the intestine because they are not live bacteria. For example, Lactobacillus
It is known that cell components of lactic acid bacteria such as casei are absorbed from the digestive organs, and as a result, exert an effect on blood pressure and stroke. For example, it has been recognized that yeast cell components such as Saccharomyces cerevisiae are also absorbed from the digestive tract, and are known to be extremely effective for maintaining health and providing nutrition. In particular, according to the Japanese Pharmacopoeia Law, it is stated that the medicinal properties of nucleic acids contained in these bacterial cell components, that is, they are effective in nutritional supplementation, metabolic function promotion, appetite enhancement, intestinal regulation, etc. . This includes, as mentioned earlier,
Servisier belongs to cocci, and casei belongs to bacilli. In principle, it is strongly resistant to acids having a pH of 3-4. For this reason, it has an effect of suppressing the growth of other harmful microorganisms, so that it is used not only for producing milk and lactic acid in foods but also as an intestinal medicine.

Although turmeric or turmeric tea is generally widely used, turmeric alone improves hepatic function regardless of pathological symptoms of various organs and organs of the digestive system or gastrointestinal symptoms. It is the fact that they are drinking for this purpose. Turmeric has traditionally been used as a bile medicine in folk medicine, but has also been used in the medical field to promote blood flow. It was necessary to improve whether the components contained in turmeric itself were sufficiently absorbed in terms of effect and utility. By the way, as for the method of using turmeric, the combination of turmeric and a lactic acid bacteria co-culture was overlooked because the pharmacological effects and the range of use of turmeric were limited depending on each purpose. In addition, does turmeric depend on cornstarch or other binders, excipients, calcium stearate, lubricants such as talc, and solids mixed with disintegrants, which are the main components alone? It was usual to drink the rhizome after decoction. From such a viewpoint, a combination of a medicinal plant such as turmeric and a lactic acid bacteria coexisting culture extract, turmeric, mugwort, strawberry, moloheiya, and other medicinal plant powdered jelly or pudding, agar and lactic acid bacteria coexisting culture extract It is necessary to consume health supplements, which are various health foods in combination.

Therefore, the present inventor has focused on the development of health foods that can maintain and promote health and sufficiently exert health effects, and has selected 12 types of compatible lactic acid bacteria from various effective bacteria. Products obtained by co-cultivating soybeans with oligosaccharides, dietary fiber such as loquat, mulberry, sasa leaves, ginkgo leaves, etc. It has successfully developed an excellent health food consisting of a combination of various herbs. Under these circumstances, the inventor of the present application has noticed that there is no functional or supplemental health food that is nutritious, easy to digest and easy to absorb from digestive tracts such as the small intestine,
As a result of paying attention to foods combining many herbs used as folk remedies such as turmeric with lactic acid bacteria co-cultivation culture, the present invention was successfully developed.

[0007]

DISCLOSURE OF THE INVENTION The present invention provides turmeric containing a lactic acid bacteria coexisting culture extract, which is a combination of a lactic acid bacteria coexisting culture extract and a medicinal plant such as turmeric, which has many effects, and other health foods of medicinal plants. The purpose is to:

[0008]

Means for Solving the Invention The present invention relates to a co-cultured culture of lactic acid bacteria and yeast, and one or several species selected from turmeric, hibiscus, guava, ginkgo, bilberry, strawberry, moloheiya, mugwort, and strawberry And foods mixed with turmeric, hibiscus, cumistin, and guava are preferred, and foods mixed with turmeric are particularly preferred. In the present invention, the term "culture" refers to a culture, a culture obtained by removing a raw material bacterium from the culture, a culture obtained by extracting an active ingredient from a culture with a solvent, or a concentrate thereof.

[0009]

BEST MODE FOR CARRYING OUT THE INVENTION The lactic acid bacteria of the present invention include Streptococcus thermophilus, Streptococcus cremoris, Streptococcus faecalis, Streptococcus lactis, Streptococcus sp.
Bulgaricus, Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus delbrueckii, Lactobacillus arabinose, Lactobacillus
Lactobacillus lactis, Lactobacillus leishmani, Lactobacillus muscicus, Lactobacillus thermophilus, Lactobacillus plantarum, Leuconostoc mesenteroides, Lactobacillus pentoaceticus, Lactobacillus eukritii, Lactobacillus bulgaricus, Streptococcus lactis, Lactobacillus acidophilus, Lactobacillus helieticus, Lactobacillus
Fermentum, Lactobacillus bifidum, Lactobacillus pentoaceticus, Lactobacillus eukriti, Lactobacillus bulgaricus, Micrococcus lactis, Lactobacillus kornchen are preferred, and at least Lactobacillus bulgaricus, Lactobacillus casei, Lactobacillus are preferred. It is particularly preferred to include pentoacetylics, Streptococcus lactis, Lactobacillus lactis.

[0010] The yeasts are Saccharomyces serivizier, Saccharomyces pastorianus, Saccharomyces intermedius, Saccharomyces validous, Saccharomyces saccharomyces ellipsisoidus, Saccharomyces marilislar, Saccharomyces manschricas, Saccharomyces saccharomyces, Saccharomyces Siassing, Saccharomyces biliformis, Saccharomyces anamensis, Saccharomyces cartilaginose, Saccharomyces awamori, Saccharomyces patatae, Saccharomyces
Coreanus, Saccharomyces robustous, Saccharomyces carlsbergensis, Saccharomyces monacensis, Saccharomyces marxianus,
Saccharomyces lactis, Saccharomyces mayor, Saccharomyces luxii, Hansenula anomala are preferred, and it is particularly preferred that they contain at least Saccharomyces cerviziger, Saccharomyces biliformis, Saccharomyces awamori and Saccharomyces lactis.

The culture medium for co-cultivation is preferably soybean, peptone, a medium containing peptone, or milk, and particularly preferably soybean. It is preferable to add oligosaccharides, dietary fibers such as loquat, mulberry, sasa leaves, and ginkgo leaves to this medium.

The coexisting culture extract is a coexisting culture of lactic acid bacteria and yeast, particularly preferably at least 5 types of lactic acid bacteria as described above and at least 4 types of yeast such as yeasts as described above. Products and secretions obtained by co-cultivating microorganisms, containing more than 20 types of amino acids, various vitamins, various minerals, and nucleic acids and other trace bioelements. Published natural medicine clinical prevention research report). Further, the effects of the products or secretions of lactic acid bacteria for each component are disclosed as follows.

Amino acids, one of the components, are one of the three major nutrients in living organisms, and are proteins that make up about 2
0 amino acids, specifically, arginine, lysine,
Histidine, phenylalanine, tyrosine, leucine, isoleucine, methionine, valine, alanine, glycine, proline, glutamic acid, serine, threonine, aspartic acid, tryptophan and cystine;
[Glutamine, asparagine] have been clarified from the analysis results. Next, nucleic acids will be described. Important nucleic acid components that transmit gene information and give instructions, such as deoxyribonucleic acid (DNA) and messenger ribonucleic acid (RNA) that determines the type of protein, coexist with the lactic acid bacteria used in the present invention. The culture is abundant. And this nucleic acid activates normal division of human body cells, prevents aging by increasing energy consumption, prevents obesity, prevents infectious diseases by improving immunity, prevents diabetes by improving hormonal balance, and improves intestinal beneficial bacteria. It has been demonstrated to be effective in increasing and activating nerve cells.

Insufficient nucleic acid, which is said to be the source of life, in the body has a very bad effect on cell production and proliferation.
It is necessary to constantly take this extract into the body. Further, specifically describing one of the components, minerals and vitamins, in addition to phosphorus, calcium, magnesium, sodium and potassium, examples of the vitamin group include biotin, folic acid, pantothenic acid and niacin. Furthermore, as fatty acids, butyric acid, acetic acid,
It contains propionic acid and lactic acid. In addition, in addition to the above-mentioned components, the presence of sugar chains themselves and amino sugars in the lactic acid bacteria co-cultured culture or extract thereof used in the present invention was confirmed by analysis. I have.

[0015] The above-mentioned lactic acid bacteria co-cultivation culture contains components necessary and important for maintaining the life of the living body, so that it has weak constitution, irregular menstruation, burns, stiff shoulders, herpes, toothache, atopic dermatitis, cataract, Effective for skin diseases, spots, freckles, hair loss prevention, coldness, constipation, bronchitis, hay fever, gastric ulcer, osteomyelitis, diabetes, high blood pressure, liver dysfunction, heart disease, stomach cancer, breast cancer, lung cancer, etc. , Is also medically recognized.

As described above, if a coexisting culture extract that exerts an effect on many diseases and pathological symptoms is consumed in a daily diet, expensive fish and meat are eaten in order to promote health maintenance and enhance natural healing power. It is possible to obtain a high-quality protein source containing a large amount of essential amino acids that cannot be synthesized very easily in the body without performing the same.

In the present invention, the effects of the bacterial cell components including the above-mentioned components can be utilized as they are in the present invention. In other words, the products and extracts stimulate the cells themselves and activate the cells, thereby activating various organs, muscles, nerves and skin in the body, which are aggregates of cells, and exhibiting an effect of preventing aging. I do. As a result, active fresh cell formation takes place in the body, and the skin and the youthfulness of the skin are constantly
Maintained by cell activation. In addition, according to the symbiotic culture extract, the activation of toxic and harmful bacteria in the intestine and the suppression of their growth are suppressed, so that the intestinal environment is purified and adjusted normally, preventing abnormal fermentation in the intestine. it can.

Further, regarding the intestinal environment, harmful fungi such as Escherichia coli and Welsh bacteria proliferate in the body, and harmful toxins such as ammonia, amines, nitrosamines, hydrogen sulfide, phenol, and tryptophan are introduced into the body or intestines. When exhaled or released, they are absorbed into the blood and travel throughout the body. As a result, the normal flow of lymph and blood is obstructed, so that the presence of harmful bacteria and toxins lowers the immune function and causes biological abnormalities and diseases. However, the lactic acid bacteria-cocultivated culture can suppress the growth of harmful bacteria and prevent the release and accumulation of endotoxins in advance, so that the main functions are not hindered.

The turmeric combined with the lactic acid bacteria coexisting culture and extract in the present invention is a commonly used kind, and is a perennial plant of the ginger family such as spring turmeric, autumn turmeric, purple turmeric (gajutsu) or white turmeric. It is a plant.
It is grown in Okinawa, India, southern China, Taiwan, Thailand, Java, Vietnam, Cambodia and Yakushima. In the present invention, spring turmeric is mainly used. However, the present invention is not limited to this, and all turmeric can be used to obtain the effect as turmeric. As described above, the rhizome contains curcumin, which has an anti-reactive oxygen effect, in addition to irritating bitter components, essential oil components such as gingiberone and turmerone.

Since such essential oil components are contained,
Among plants, it has not only helped to maintain and promote health, but also has pharmacological effects, such as promoting secretion of gastric juice, saliva and bile, inotropic action such as dikitalis, and preventing the growth of necrotic cells. I have. Minerals and other components contained in 100 g of spring turmeric are 2.8% water, 9.9% protein, 4.3% lipids, 5.2% fiber, 6.2% ash.
%, Carbohydrate 70.7%, phosphorus 295 mg, iron 106 mg,
169 mg of calcium, 1.75% of potassium, 268 mg of magnesium <0.89% of tannin. further,
According to the analysis results of the Japan Food Research Laboratories, curcumol, α-curcumene, flavonoids, azulene, cineol, dietary fiber, and the like have been confirmed as components contained in turmeric in addition to the components described above. Similar to the effects of turmeric, lactic acid bacteria-coexisting cultures also have a blood purification effect, and thus exhibit an interaction in combination with turmeric.

[0021] The lactic acid bacteria co-culture of the present invention,
Foods with medicinal plants, for example, after adding the rhizome of finely divided dried turmeric to the liquid lactic acid bacteria co-cultivation culture and mixing, adding cornstarch and calcium stearate to this mixture and stirring to granulate , And the resulting granules are sieved through an appropriate sieve and dried. After drying, a lubricant is added, and the mixture is sieved again, and then potato powder is added and mixed as a disintegrant. Finally, the mixture is tabletted to obtain a tablet product of food.

The food of the present invention is not particularly limited to granules, tablets and the like, but tablets are particularly preferable from the viewpoint of convenience of use and ease of ingestion.

The food of the present invention may be used as it is, or may be processed using miso, salt, vinegar, sugar, agar, or the like. Examples of processed foods include pickles, jellies, yokan, ice cream, castella, buns, and soft drinks. Further, the food of the present invention is liquid, colloidal, powdery, granular, uncoated tablets,
It can be of any shape, such as a coated tablet. For example, when producing powders or tablets, excipients, binders, disintegrants, anti-caking agents, lubricants and the like are used as necessary, and examples thereof are as follows. Usable excipients include, but are not limited to, for example, starch, lactose, sucrose, glucose, microcrystalline cellulose, calcium phosphate, magnesium carbonate, kaolin, hydrotalcite, magnesium aluminate metasilicate, aluminum hydroxide Used such as magnesium. As the binding material, ordinary materials are used, for example, agar,
As sodium alginate, dextrin, gelatin, glucose, gum arabic, tragacanth, lactose starch, sugar solution, sucrose, HPMC, HPC, vinyl acetate, and disintegrants, conventional ones are used, for example, starch, alginic acid, agar, Silicic anhydride, CM
C, HPS, etc. are used. As the anti-caking material, a usual one is used. For example, synthetic calcium silicate or the like is used.
As the lubricating agent, ordinary ones are used. For example, stearic acid, calcium stearate, magnesium stearate, talc, corn starch, lactose, mannitol, wax and the like are used.
As the coating agent, those conventionally used are used. For example, resins, saccharides and the like are used, and shellac, sugar solution and the like are used.

[0024]

EXAMPLES Example 1 Fine-grained dried turmeric rhizomes were added to a liquid lactic acid bacteria-coexisting culture and mixed, and then a mixture obtained by adding corn starch and calcium stearate was stirred and granulated. The resulting granules are sieved through a sieve of a suitable diameter and dried. After being dried, a lubricant is added, and the mixture is sieved again. Then, potato powder is added as a disintegrant, mixed and tableted to obtain a target tablet product.

Example 2 Powdered hibiscus flowers were added to a liquid culture of lactic acid bacteria coexisting and mixed, and then corn starch and magnesium stearate were added thereto. And the resulting granules are dried. After drying, adding a lubricant and sieving again, adding potato powder as a disintegrant, mixing and tableting,
Obtain the desired tablet product.

Example 3 After powdered dried Kumis Kectin leaves were added to a liquid lactic acid bacteria co-cultivation culture and mixed, corn starch and calcium stearate were added thereto, and the resulting mixture was stirred and granulated to obtain an appropriate diameter. And the resulting granules are dried. After drying, a lubricant is added, the mixture is sieved again, and then potato powder is added and mixed as a disintegrant, and the mixture is compressed into tablets to obtain the desired tablet.

Example 4 Finely divided guava leaves were mixed with a liquid culture of lactic acid bacteria, mixed with corn starch and magnesium stearate, and the resulting mixture was stirred and granulated. The granules obtained are sieved through a sieve and dried. After being dried, a lubricant is added, and the mixture is sieved again. Then, potato powder is added as a disintegrant, mixed and tableted to obtain a target tablet product.

Example 5 A mixed solution composed of a lactic acid bacteria co-cultivation culture, cumistin powder and water is added to a mixed powder consisting of dried turmeric powder, lactose and glucose, and kneaded. After drying the obtained kneaded material, the kneaded material is sized by a sizing machine into granules of a certain size. Next, a lubricant is added to the sized granules,
This is transferred to a tableting machine, and the obtained granules are coated with shellac and dried to obtain a desired final product.

Example 6 A mixed solution consisting of a lactic acid bacteria co-cultivation culture, a concentrated extract of cumistin and water is added to a mixed powder of dried turmeric powder, lactose, glucose and cellulose, and kneaded.
After drying the obtained kneaded material, the kneaded material is sized by a sizing machine into granules of a certain size. Next, a sugar ester is added as a lubricant to the sized granules, and the mixture is transferred to a tableting machine. The obtained granules are coated with shellac and dried to obtain a desired final product.

Example 7 Finely divided ginkgo leaves were added to a liquid lactic acid bacteria co-culture, mixed, and then cornstarch and magnesium stearate were added. The granules obtained are sieved through a sieve and dried. After being dried, a lubricant is added, and the mixture is sieved again. Then, potato powder is added as a disintegrant, mixed and tableted to obtain a target tablet product.

[0031]

According to the invention of the present application, a lactic acid bacteria-coexisting culture and turmeric, cumistin, hibiscus, guava,
By combining one or two or more medicinal plants such as ginkgo, long-lived grass, dokudami, loquat rhizome, leaves, flowers, etc., not only can the effect of the lactic acid bacteria co-cultivation culture alone and the effect of each medicinal herb be taken Thus, it is possible to obtain a health food exhibiting a synergistic effect and a health maintenance effect by a combination thereof.

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Claims (8)

[Claims] 1. A co-cultivation culture of lactic acid bacteria and yeast, turmeric, cumistin, hibiscus, guava, ginkgo,
A food comprising a mixture with one or several kinds of medicinal plants selected from loquat, mugwort, strawberry, long-lived grass, dokudami, and moroheiya. 2. The food product according to claim 1, wherein the lactic acid bacterium contains at least Lactobacillus bulgaricus, Lactobacillus casei, Lactobacillus pentoaceticus, Streptococcus lactis, and Lactobacillus lactis. 3. The method according to claim 2, wherein the yeast is at least Saccharomyces.
3. The food according to claim 1, wherein the food comprises Seribije, Saccharomyces biliformis, Saccharomyces awamori, and Saccharomyces lactis. 4. The food according to claim 1, wherein the culture medium for co-cultivation contains soybean. 5. The food according to claim 1, wherein the medicinal plant contains turmeric. 6. The food according to claim 1, wherein the medicinal plant contains turmeric and cumistin. 7. The food according to claim 1, wherein the food is a processed food obtained by processing on agar. 8. A co-cultivation culture of lactic acid bacteria and yeast, turmeric, cumistin, hibiscus, guava, ginkgo,
The method for producing a food according to any one of claims 1 to 7, wherein one or more kinds selected from loquat, mugwort, strawberry, long-lived grass, dokudami, and moroheiya are mixed.