CN101463376A - Neutralization sampling solution for medical object surface - Google Patents
Neutralization sampling solution for medical object surface Download PDFInfo
- Publication number
- CN101463376A CN101463376A CNA2007101157306A CN200710115730A CN101463376A CN 101463376 A CN101463376 A CN 101463376A CN A2007101157306 A CNA2007101157306 A CN A2007101157306A CN 200710115730 A CN200710115730 A CN 200710115730A CN 101463376 A CN101463376 A CN 101463376A
- Authority
- CN
- China
- Prior art keywords
- object surface
- medical object
- histidine
- effect
- sampling liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Abstract
The invention relates to a medical object surface neutralization sampling liquid. The main components comprise tween-80, histidine, cysteine and bouillon which are mixed into a mixture in proportion. The tween-80, the histidine, the cysteine and the bouillon can take chemical reaction with residual disinfection solution in the medical object surface to generate a neutralizing product which does not have the effect of killing or restraining the growth of experimental microorganism, does not damage culture component and does not affect physical physical properties. The medical object surface neutralization sampling liquid has practical and reliable neutralizing effect on the corresponding medical object surface disinfection solution. The medical object surface neutralization sampling liquid is suitable for evaluating the disinfection effect of the medical object surface. The medical object surface neutralization sampling liquid has the advantages as follows: the medical object surface neutralization sampling liquid has practical and reliable neutralizing effect on the corresponding medical object surface disinfection solution; a neutralizing agent or a product produced in the reaction of the neutralizing agent and the medial object surface neutralization sampling liquid does not have effect of killing or restraining the growth of the experimental microorganism; and the medical object surface neutralization sampling liquid does not damage the culture component and also does not affect the physical properties.
Description
Technical field the present invention relates in a kind of medical object surface and sample solution, and its main component is that tween-80, Histidine, halfcystine, meat soup are mixed in proportion into mixture.The key problem of disinfection experiment is to estimate the sterilization and the bacteriostatic action of medical object surface disinfection factor.Estimate the disinfection of medical object surface, must strictly grasp action time.Thimerosal and microorganism touch after the preset time, must remove its effect immediately, so just can accurately obtain the data of medical object surface thimerosal action effect; Simultaneously must not contain remaining thimerosal in the sample after taking to sterilize.To prevent that in recover cultivating microorganism from continuing to be subjected to the effect of thimerosal.Therefore, the experiment that any one estimates medical object surface all must have the reliable method of removing remaining thimerosal.Do not adopt the experiment of removing remaining thimerosal measure, should think serious mistake in design, the result who draws according to such experiment is insecure.The chemistry neutralisation is the thimerosal method of at present the most frequently used removal remnants, and its advantage is that method is simple, and is easy to use, reliable for effect.Can be used for estimating the disinfection of medical treatment in the medical object surface with sample solution.Existing thimerosal neutralizing agent kind is a lot, and common have acid, alkali, absorption, dilution, centrifugal a, filtration etc.The above-mentioned screening of all passing through strictness also can't not determined its working concentration; Corresponding thimerosal do not had solid neutralizing effect; Neutralizing agent itself or with the product of thimerosal reaction the experiment microorganism is had killing or suppress the effect of its growth; To cultivating composition destruction is arranged, also influence its physical behavior.Along with the sterilization progress of research, both at home and abroad to the research of neutralizing agent also in continuous development.The disinfection person wishes to have always and a kind ofly can overcome in the insufficient medical object surface of above-mentioned neutralizing agent and sample solution.
Background technology the object of the present invention is to provide and a kind ofly can overcome in the insufficient medical object surface of existing sterilization neutralizing agent and sample solution, compares with other class neutralizing agent to possess following characteristics: corresponding medical object surface thimerosal is had solid neutralizing effect; Neutralizing agent itself or with medical object surface in and the product of sample solution reaction the experiment microorganism is not had killing or suppresses the effect of its growth; Do not have destruction to cultivating composition, also do not influence its physical behavior.
Summary of the invention main points of the present invention are to select suitable component, and rationally are mixed, through heat, dissolve, technology such as mixing, cooling, packing, high-temperature sterilization forms in a kind of medical object surface and sample solution.
The prescription following (component and weight percent % thereof) that the present invention selects: tween-80 (1.0-3.0); Histidine (1.0-3.0); Halfcystine (0.1-0.3); Meat soup (1.0-5.0); Purified water adds to 100.
Tween-80, Histidine, halfcystine, meat soup can with thimerosal generation chemical reaction in the medical object surface of remnants, generate to the experiment microorganism do not kill or suppress its growth effect, do not have destruction to cultivating composition, physical behavior not have the neutralized reaction product that influences.Corresponding medical object surface thimerosal had solid neutralizing effect.
The preparation method of product of the present invention is:
1), tween-80, meat soup are heated in proportion, dissolved.
2), Histidine, halfcystine are dissolved in the pure water 54 ℃ of heating in proportion, cooling.
3), dissolved tween-80, meat soup are joined in cooling back Histidine, the halfcystine solution mixing, cooling by proportioning
After carry out packing, 105 ℃ the sterilization 15 minutes.Check, warehousing after passing.
The present invention has the following advantages: corresponding medical object surface thimerosal is had solid neutralizing effect; Neutralizing agent itself or with medical object surface in and the product of sample solution reaction the experiment microorganism is not had killing or suppresses the effect of its growth; Do not have destruction to cultivating composition, also do not influence its physical behavior.
The present invention is described in further detail below in conjunction with embodiment for embodiment:
Be configured according to following table institute column data (weight percent %) and described step thereof:
Prescription one:
Tween-80 1.0-3.0
Histidine 1.0-3.0
Halfcystine 0.1-0.3
Meat soup 1.0-5.0
Purified water adds to 100
Prescription two:
Tween-80 1.5-3.0
Histidine 1.5-3.0
Halfcystine 0.15-0.3
Meat soup 2.0-5.0
Purified water adds to 100
Prescription three:
Tween-80 1.0-2.0
Histidine 1.0-2.0
Halfcystine 0.1-0.25
Meat soup 1.0-4.0
Purified water adds to 100
Prescription four:
Tween-80 1.5-2.0
Histidine 1.5-2.0
Halfcystine 0.15-0.25
Meat soup 2.0-4.0
Purified water adds to 100.
Claims (2)
1, the present invention relates in a kind of medical object surface and sample solution, its main component is that tween-80, Histidine, halfcystine, meat soup are mixed in proportion into mixture; It is characterized in that having following prescription (component and weight percent % thereof): tween-80 (1.0-3.0); Histidine (1.0-3.0); Halfcystine (0.1-0.3); Meat soup (1.0-5.0); Purified water adds to 100.
2, in the described medical object surface of a kind of claim 1 and the preparation method of sample solution, it is characterized in that having following step:
1), tween-80, meat soup are heated in proportion, dissolved;
2), Histidine, halfcystine are dissolved in the pure water 54 ℃ of heating in proportion, cooling;
3), dissolved tween-80, meat soup are joined in cooling back Histidine, the halfcystine solution by proportioning, mix, carry out packing after the cooling, 105 ℃ of sterilizations 15 minutes, check, warehousing after passing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101157306A CN101463376A (en) | 2007-12-18 | 2007-12-18 | Neutralization sampling solution for medical object surface |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101157306A CN101463376A (en) | 2007-12-18 | 2007-12-18 | Neutralization sampling solution for medical object surface |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101463376A true CN101463376A (en) | 2009-06-24 |
Family
ID=40804166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007101157306A Pending CN101463376A (en) | 2007-12-18 | 2007-12-18 | Neutralization sampling solution for medical object surface |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101463376A (en) |
-
2007
- 2007-12-18 CN CNA2007101157306A patent/CN101463376A/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Reddy et al. | Sterilization methods in orthodontics-A Review | |
| CN103636674A (en) | Peracetic acid disinfectant and preparation method thereof | |
| CN101463385A (en) | Medical institution personnel hand neutralization sampling solution | |
| Bocci et al. | Ozonation of human HIV-infected plasmas for producing a global vaccine: How HIV-patients may help fight the HIV pandemia | |
| CN101463376A (en) | Neutralization sampling solution for medical object surface | |
| CN101698878A (en) | Neutralization sampling liquid for phenolic disinfectant | |
| CN101698867A (en) | Neutralizing and sampling solution for guanidine disinfectant | |
| CN101698865A (en) | Neutralizing elution sample solution for chloral disinfection | |
| CN1639575A (en) | In vitro model for priocidal activity | |
| CN101698868A (en) | Cysteine neutralizing and sampling liquid of plant disinfectant | |
| CN103131749A (en) | Biological enzyme neutralizer | |
| CN102302039B (en) | Dication quaternary ammonium complex iodine disinfectant, and application thereof | |
| CN101463377A (en) | Biological enzyme neutralization agent | |
| Smith et al. | In vitro evaluation of cleaning efficacy of detergents recommended for use on dental instruments | |
| CN101698877A (en) | Sampling solution for neutralizing marine organism disinfecting solution | |
| CN101698864A (en) | Air sampling neutralization culture medium in public sanitary place | |
| CN101027981A (en) | Plant disinfectant neutralizer | |
| CN101698863A (en) | Sample solution for neutralizing disinfection solution containing quaternary ammonium salt | |
| CN101565727A (en) | Complex neutralizer for disinfectant | |
| CN101027982A (en) | Phenolic disinfectant neutralizer | |
| CN101027983A (en) | Compound disinfectant neutralizer | |
| CN101027980A (en) | Marine biological disinfectant neutralizer | |
| CN101697778A (en) | Nutrient broth for neutralizing iodine-containing decontaminant | |
| Oral et al. | Vaporized H2O2 decontamination against surrogate viruses for the reuse of N95 respirators in the COVID-19 emergency | |
| CN103194526A (en) | Childcare institution disinfection effect supervision and sampling neutralizing liquid |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20090624 |