CN101448818A - 用于抑制整联蛋白的新的杂环化合物及其应用 - Google Patents

用于抑制整联蛋白的新的杂环化合物及其应用 Download PDF

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Publication number
CN101448818A
CN101448818A CNA2007800171978A CN200780017197A CN101448818A CN 101448818 A CN101448818 A CN 101448818A CN A2007800171978 A CNA2007800171978 A CN A2007800171978A CN 200780017197 A CN200780017197 A CN 200780017197A CN 101448818 A CN101448818 A CN 101448818A
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ylamino
methyl
compound
phenyl
ethyl
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Chinese (zh)
Inventor
刚瑟·齐施勒斯凯
罗兰·斯特拉齐
法兰克·奥斯特坎普
德尔克·舒瓦恩
杰德·胡梅尔
霍格尔·卡赫夫
格特·察恩
朵瑞特·弗斯梅尔
克劳蒂亚·克利斯能-艾布雷特
优瑞奇·赖内克
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Jerini AG
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Jerini AG
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Publication of CN101448818A publication Critical patent/CN101448818A/zh
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
CNA2007800171978A 2006-05-12 2007-05-14 用于抑制整联蛋白的新的杂环化合物及其应用 Pending CN101448818A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06009872 2006-05-12
EP06009872.0 2006-05-12

Publications (1)

Publication Number Publication Date
CN101448818A true CN101448818A (zh) 2009-06-03

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CNA2007800171978A Pending CN101448818A (zh) 2006-05-12 2007-05-14 用于抑制整联蛋白的新的杂环化合物及其应用

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Country Link
US (1) US8309735B2 (https=)
EP (1) EP2024357A2 (https=)
JP (1) JP2009536961A (https=)
KR (1) KR20090017512A (https=)
CN (1) CN101448818A (https=)
AR (1) AR060901A1 (https=)
AU (1) AU2007251756A1 (https=)
BR (1) BRPI0711659A2 (https=)
CA (1) CA2652101A1 (https=)
IL (1) IL194946A0 (https=)
MX (1) MX2008014345A (https=)
RU (1) RU2008148943A (https=)
TW (1) TW200811164A (https=)
WO (1) WO2007131764A2 (https=)
ZA (1) ZA200809074B (https=)

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CN108794496A (zh) * 2018-04-28 2018-11-13 北京施安泰医药技术开发有限公司 一类cdk抑制剂、其药物组合物、制备方法及用途

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AR059224A1 (es) 2006-01-31 2008-03-19 Jerini Ag Compuestos para la inhibicion de integrinas y uso de estas
TW200811164A (en) 2006-05-12 2008-03-01 Jerini Ag New heterocyclic compounds for the inhibition of integrins and use thereof
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WO2010062829A1 (en) * 2008-11-28 2010-06-03 Lexicon Pharmaceuticals, Inc. Tryptophan hydroxylase inhibitors for treating osteoporosis
UA110924C2 (uk) * 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
CN102711749A (zh) * 2009-11-05 2012-10-03 莱西肯医药有限公司 用于癌症治疗的色氨酸羟化酶抑制剂
WO2015048819A1 (en) 2013-09-30 2015-04-02 The Regents Of The University Of California Anti-alphavbeta1 integrin compounds and methods
CN103588770B (zh) * 2013-11-27 2016-08-17 武汉尚赛光电科技有限公司 1，2，4-噻二唑衍生物及其作为电致发光材料的应用
WO2016145258A1 (en) 2015-03-10 2016-09-15 The Regents Of The University Of California Anti-alphavbeta1 integrin inhibitors and methods of use
JP7658578B2 (ja) 2019-02-28 2025-04-08 国立大学法人大阪大学 タンパク質及び／又はペプチド修飾用分子

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108794496A (zh) * 2018-04-28 2018-11-13 北京施安泰医药技术开发有限公司 一类cdk抑制剂、其药物组合物、制备方法及用途
CN108794496B (zh) * 2018-04-28 2020-04-24 北京施安泰医药技术开发有限公司 一类cdk抑制剂、其药物组合物、制备方法及用途

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TW200811164A (en) 2008-03-01
WO2007131764A2 (en) 2007-11-22
CA2652101A1 (en) 2007-11-22
RU2008148943A (ru) 2010-06-20
BRPI0711659A2 (pt) 2012-01-17
AU2007251756A1 (en) 2007-11-22
AR060901A1 (es) 2008-07-23
IL194946A0 (en) 2009-08-03
US20090203745A1 (en) 2009-08-13
MX2008014345A (es) 2008-11-27
KR20090017512A (ko) 2009-02-18
US8309735B2 (en) 2012-11-13
EP2024357A2 (en) 2009-02-18
JP2009536961A (ja) 2009-10-22
WO2007131764A3 (en) 2008-01-10
ZA200809074B (en) 2009-08-26

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