CN101432279A - 吡啶基甲基哌嗪和吡啶基甲基哌啶衍生物的n-氧化物 - Google Patents

吡啶基甲基哌嗪和吡啶基甲基哌啶衍生物的n-氧化物 Download PDF

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Publication number
CN101432279A
CN101432279A CNA2007800157788A CN200780015778A CN101432279A CN 101432279 A CN101432279 A CN 101432279A CN A2007800157788 A CNA2007800157788 A CN A2007800157788A CN 200780015778 A CN200780015778 A CN 200780015778A CN 101432279 A CN101432279 A CN 101432279A
Authority
CN
China
Prior art keywords
compound
nitrogen atom
oxides
fluorophenyl
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2007800157788A
Other languages
English (en)
Chinese (zh)
Inventor
M·P·M·范艾尔
P·H·范埃姆斯特达姆
G·A·巴福
J·A·巴克尔
C·丹柏司腾
A·H·J·赫尔曼斯
J·卓格达格尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Healthcare Products BV
Original Assignee
Solvay Pharmaceuticals BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37198739&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN101432279(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Solvay Pharmaceuticals BV filed Critical Solvay Pharmaceuticals BV
Publication of CN101432279A publication Critical patent/CN101432279A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNA2007800157788A 2006-05-02 2007-04-25 吡啶基甲基哌嗪和吡啶基甲基哌啶衍生物的n-氧化物 Pending CN101432279A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60/796,551 2006-05-02
EP06113393.0 2006-05-02
EP06113393 2006-05-02

Publications (1)

Publication Number Publication Date
CN101432279A true CN101432279A (zh) 2009-05-13

Family

ID=37198739

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2007800157788A Pending CN101432279A (zh) 2006-05-02 2007-04-25 吡啶基甲基哌嗪和吡啶基甲基哌啶衍生物的n-氧化物

Country Status (16)

Country Link
EP (1) EP2024363B1 (enExample)
JP (1) JP2009535374A (enExample)
CN (1) CN101432279A (enExample)
AR (1) AR060832A1 (enExample)
AU (1) AU2007247251B2 (enExample)
BR (1) BRPI0710792A2 (enExample)
CA (1) CA2649479A1 (enExample)
CL (1) CL2007001245A1 (enExample)
EA (1) EA200870492A1 (enExample)
MX (1) MX2008013887A (enExample)
PE (1) PE20080064A1 (enExample)
SA (1) SA07280218B1 (enExample)
TW (1) TW200811150A (enExample)
UA (1) UA96756C2 (enExample)
WO (1) WO2007128694A1 (enExample)
ZA (1) ZA200809112B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2009011020A (es) 2007-04-12 2009-10-30 Nsab Af Neurosearch Sweden Ab Derivados de n-oxido y/o di-n-oxido de los estabilizadores/modulad ores del receptor de dopamina que exhiben perfiles mejorados de los efectos secundarios cardiovasculares.
EP2787997A4 (en) 2011-12-08 2015-05-27 Ivax Int Gmbh HYDROBROMIDE SALT OF PRIDOPIDINE
BR112014024672A8 (pt) 2012-04-04 2018-04-03 Ivax Int Gmbh Composições farmacêuticas para terapia de combinação
GB201801128D0 (en) 2018-01-24 2018-03-07 Univ Oxford Innovation Ltd Compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE81975T1 (de) 1984-12-21 1992-11-15 Duphar Int Res Arzneimittel mit psychotroper wirkung.
TW530054B (en) 1997-09-24 2003-05-01 Duphar Int Res New piperazine and piperidine compounds

Also Published As

Publication number Publication date
AR060832A1 (es) 2008-07-16
MX2008013887A (es) 2009-01-29
SA07280218B1 (ar) 2010-10-03
AU2007247251A1 (en) 2007-11-15
CA2649479A1 (en) 2007-11-15
UA96756C2 (en) 2011-12-12
EP2024363A1 (en) 2009-02-18
JP2009535374A (ja) 2009-10-01
EP2024363B1 (en) 2012-08-01
TW200811150A (en) 2008-03-01
AU2007247251B2 (en) 2011-11-03
ZA200809112B (en) 2009-07-29
PE20080064A1 (es) 2008-03-19
WO2007128694A1 (en) 2007-11-15
CL2007001245A1 (es) 2008-05-30
BRPI0710792A2 (pt) 2011-06-21
EA200870492A1 (ru) 2009-04-28

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