AU2007247251B2 - N-oxides of pyridylmethylpiperazine and -piperidine derivatives - Google Patents

N-oxides of pyridylmethylpiperazine and -piperidine derivatives Download PDF

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Publication number
AU2007247251B2
AU2007247251B2 AU2007247251A AU2007247251A AU2007247251B2 AU 2007247251 B2 AU2007247251 B2 AU 2007247251B2 AU 2007247251 A AU2007247251 A AU 2007247251A AU 2007247251 A AU2007247251 A AU 2007247251A AU 2007247251 B2 AU2007247251 B2 AU 2007247251B2
Authority
AU
Australia
Prior art keywords
oxide
piperazine
compound
dihydro
oxides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2007247251A
Other languages
English (en)
Other versions
AU2007247251A1 (en
Inventor
Johan Antoine Bakker
Gerrit A. Barf
Cathaline Den Besten
Arnoldus H.J. Herremans
Marcel P.M. Van Aar
Peter H. Van Amsterdam
Jan Zorgdrager
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Healthcare Products BV
Original Assignee
Solvay Pharmaceuticals BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37198739&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2007247251(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Solvay Pharmaceuticals BV filed Critical Solvay Pharmaceuticals BV
Publication of AU2007247251A1 publication Critical patent/AU2007247251A1/en
Application granted granted Critical
Publication of AU2007247251B2 publication Critical patent/AU2007247251B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2007247251A 2006-05-02 2007-04-25 N-oxides of pyridylmethylpiperazine and -piperidine derivatives Ceased AU2007247251B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US79655106P 2006-05-02 2006-05-02
EP06113393 2006-05-02
US60/796,551 2006-05-02
EP06113393.0 2006-05-02
PCT/EP2007/054048 WO2007128694A1 (en) 2006-05-02 2007-04-25 N-oxides of pyridylmethylpiperazine and -piperidine derivatives

Publications (2)

Publication Number Publication Date
AU2007247251A1 AU2007247251A1 (en) 2007-11-15
AU2007247251B2 true AU2007247251B2 (en) 2011-11-03

Family

ID=37198739

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007247251A Ceased AU2007247251B2 (en) 2006-05-02 2007-04-25 N-oxides of pyridylmethylpiperazine and -piperidine derivatives

Country Status (16)

Country Link
EP (1) EP2024363B1 (enExample)
JP (1) JP2009535374A (enExample)
CN (1) CN101432279A (enExample)
AR (1) AR060832A1 (enExample)
AU (1) AU2007247251B2 (enExample)
BR (1) BRPI0710792A2 (enExample)
CA (1) CA2649479A1 (enExample)
CL (1) CL2007001245A1 (enExample)
EA (1) EA200870492A1 (enExample)
MX (1) MX2008013887A (enExample)
PE (1) PE20080064A1 (enExample)
SA (1) SA07280218B1 (enExample)
TW (1) TW200811150A (enExample)
UA (1) UA96756C2 (enExample)
WO (1) WO2007128694A1 (enExample)
ZA (1) ZA200809112B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101711236B (zh) * 2007-04-12 2012-10-31 Nsab神经研究瑞典公司分公司 表现出改善的心血管副作用特性的多巴胺受体稳定剂/调节剂的n-氧化物和/或二-n-氧化物衍生物
MX347209B (es) 2011-12-08 2017-04-19 Teva Pharmaceuticals Int Gmbh La sal de bromhidrato de pridopidina.
AU2013243461A1 (en) 2012-04-04 2014-11-06 Teva Pharmaceuticals International Gmbh Pharmaceutical compositions for combination therapy
GB201801128D0 (en) 2018-01-24 2018-03-07 Univ Oxford Innovation Ltd Compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3586794T2 (de) 1984-12-21 1993-05-27 Duphar Int Res Arzneimittel mit psychotroper wirkung.
TW530054B (en) 1997-09-24 2003-05-01 Duphar Int Res New piperazine and piperidine compounds

Also Published As

Publication number Publication date
JP2009535374A (ja) 2009-10-01
UA96756C2 (en) 2011-12-12
AR060832A1 (es) 2008-07-16
CA2649479A1 (en) 2007-11-15
MX2008013887A (es) 2009-01-29
AU2007247251A1 (en) 2007-11-15
TW200811150A (en) 2008-03-01
BRPI0710792A2 (pt) 2011-06-21
EP2024363B1 (en) 2012-08-01
EA200870492A1 (ru) 2009-04-28
ZA200809112B (en) 2009-07-29
WO2007128694A1 (en) 2007-11-15
CL2007001245A1 (es) 2008-05-30
SA07280218B1 (ar) 2010-10-03
EP2024363A1 (en) 2009-02-18
PE20080064A1 (es) 2008-03-19
CN101432279A (zh) 2009-05-13

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired