CN101418340B - B-raf激酶抑制剂易感性的诊断检测 - Google Patents

B-raf激酶抑制剂易感性的诊断检测 Download PDF

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CN101418340B
CN101418340B CN200810173745.2A CN200810173745A CN101418340B CN 101418340 B CN101418340 B CN 101418340B CN 200810173745 A CN200810173745 A CN 200810173745A CN 101418340 B CN101418340 B CN 101418340B
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seq
probe
braf
mutation
raf
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CN101418340A (zh
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R·兰兰德
T·夏普
S·威尔
L·吴
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F Hoffmann La Roche AG
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Health & Medical Sciences (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN200810173745.2A 2007-09-11 2008-09-10 B-raf激酶抑制剂易感性的诊断检测 Active CN101418340B (zh)

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US99339107P 2007-09-11 2007-09-11
US60/993,391 2007-09-11
US60/993391 2007-09-11

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CN102816851A (zh) * 2012-08-29 2012-12-12 苏州旷远生物分子技术有限公司 用于检测braf基因v600e突变的引物、探针、试剂盒及方法
CN106148497A (zh) * 2015-04-09 2016-11-23 上海济远生物科技有限公司 Braf基因突变检测试剂盒及其应用
KR101775356B1 (ko) 2015-07-06 2017-09-06 재단법인 아산사회복지재단 Parp 및 탄키라제 동시 저해제에 대한 감수성 결정 방법
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Publication number Publication date
PT2036990E (pt) 2014-06-12
CN101418340A (zh) 2009-04-29
JP6787651B2 (ja) 2020-11-18
JP2015198659A (ja) 2015-11-12
DK2036990T3 (da) 2014-06-30
CA2639416A1 (en) 2009-03-11
JP2009077712A (ja) 2009-04-16
PL2036990T3 (pl) 2014-09-30
CA2639416C (en) 2019-12-31
HRP20140608T1 (hr) 2014-08-15
EP2036990A1 (en) 2009-03-18
ES2471097T3 (es) 2014-06-25
SI2036990T1 (sl) 2014-07-31
EP2036990B1 (en) 2014-04-02

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