CN101410120A - 抗炎的膦酸酯化合物 - Google Patents

Info

Publication number

CN101410120A

CN101410120A CN2004800145255A CN200480014525A CN101410120A CN 101410120 A CN101410120 A CN 101410120A CN 2004800145255 A CN2004800145255 A CN 2004800145255A CN 200480014525 A CN200480014525 A CN 200480014525A CN 101410120 A CN101410120 A CN 101410120A

Authority

CN

China

Prior art keywords

conjugate

compound

general formula

groups

independently

Prior art date

2003-04-25

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

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• UEZVMMHDMIWARA-UHFFFAOYSA-M phosphonate Chemical group [O-]P(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-M 0.000 claims description 104
• 229910052757 nitrogen Inorganic materials 0.000 claims description 98
• 125000004432 carbon atom Chemical group C* 0.000 claims description 81
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• 239000004480 active ingredient Substances 0.000 claims description 47
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• 125000000623 heterocyclic group Chemical group 0.000 claims description 37
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• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 28
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• 125000000041 C6-C10 aryl group Chemical group 0.000 claims description 2
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• 125000004104 aryloxy group Chemical group 0.000 claims description 2
• 125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 claims description 2
• 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 2
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• ISIJQEHRDSCQIU-UHFFFAOYSA-N tert-butyl 2,7-diazaspiro[4.5]decane-7-carboxylate Chemical compound C1N(C(=O)OC(C)(C)C)CCCC11CNCC1 ISIJQEHRDSCQIU-UHFFFAOYSA-N 0.000 claims description 2
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• CKLJMWTZIZZHCS-UWTATZPHSA-N D-aspartic acid Chemical compound OC(=O)[C@H](N)CC(O)=O CKLJMWTZIZZHCS-UWTATZPHSA-N 0.000 claims 1
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