CN101389656A - 抗骨膜素的抗体和含有该抗体的用于预防或治疗骨膜素相关疾病的药物组合物 - Google Patents
抗骨膜素的抗体和含有该抗体的用于预防或治疗骨膜素相关疾病的药物组合物 Download PDFInfo
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- CN101389656A CN101389656A CNA2006800533635A CN200680053363A CN101389656A CN 101389656 A CN101389656 A CN 101389656A CN A2006800533635 A CNA2006800533635 A CN A2006800533635A CN 200680053363 A CN200680053363 A CN 200680053363A CN 101389656 A CN101389656 A CN 101389656A
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cardiology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Microbiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Neurology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
Abstract
Description
No. | OD值 |
12345678910 | 0.410.370.680.240.330.320.330.320.120.3 |
Claims (34)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005380009 | 2005-12-28 | ||
JP380009/2005 | 2005-12-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN101389656A true CN101389656A (zh) | 2009-03-18 |
Family
ID=38228283
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNA2006800533635A Pending CN101389656A (zh) | 2005-12-28 | 2006-12-28 | 抗骨膜素的抗体和含有该抗体的用于预防或治疗骨膜素相关疾病的药物组合物 |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1978034B2 (zh) |
JP (1) | JP5019464B2 (zh) |
KR (1) | KR101363695B1 (zh) |
CN (1) | CN101389656A (zh) |
AU (1) | AU2006334029B2 (zh) |
BR (1) | BRPI0620747A2 (zh) |
CA (1) | CA2635849C (zh) |
RU (1) | RU2008130898A (zh) |
WO (1) | WO2007077934A1 (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103688171A (zh) * | 2010-12-16 | 2014-03-26 | 弗·哈夫曼-拉罗切有限公司 | 与th2抑制相关的诊断和治疗 |
CN114364400A (zh) * | 2019-09-11 | 2022-04-15 | 勃林格殷格翰国际加拿大公司 | 使用pd-1轴抑制剂及抗骨膜蛋白抗体治疗癌症的方法 |
WO2023036305A1 (zh) * | 2021-09-13 | 2023-03-16 | 沈阳眼产业技术研究院有限公司 | 抗periostin人源化单克隆抗体及其制备方法与应用 |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8017119B2 (en) | 2005-12-28 | 2011-09-13 | Daiichi Sankyo Company, Ltd. | Antibody against periostin, and a pharmaceutical composition comprising it for preventing or treating a disease in which periostin is involved |
CN101888855A (zh) * | 2007-06-27 | 2010-11-17 | 阿斯比奥制药株式会社 | 含有由抗骨膜素的外显子-17编码的肽的抗体的癌症治疗剂 |
EP2295599B1 (en) * | 2008-06-05 | 2013-07-31 | Saga University | Method for detection of idiopathic interstitial pneumonia |
WO2010096713A2 (en) * | 2009-02-20 | 2010-08-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Method for the diagnosis of age-associated vascular disorders |
SG10201408247SA (en) * | 2009-02-24 | 2015-02-27 | Esbatech Alcon Biomed Res Unit | Methods for identifying immunobinders of cell-surface antigens |
JP5555940B2 (ja) * | 2010-04-14 | 2014-07-23 | 国立大学法人佐賀大学 | 増殖糖尿病網膜症の検出方法および予防・治療剤のスクリーニング方法 |
WO2013035799A1 (ja) | 2011-09-06 | 2013-03-14 | 株式会社シノテスト | ペリオスチンの特定領域に結合する抗体及びこれを用いたペリオスチンの測定方法 |
WO2013038696A1 (ja) | 2011-09-15 | 2013-03-21 | 国立大学法人名古屋大学 | 胸膜中皮腫患者の早期発見のための分子マーカー及びその発現解析方法 |
FR2992221A1 (fr) * | 2012-06-22 | 2013-12-27 | Centre Nat Rech Scient | Modification des effets immunomodulateurs des cellules |
EP2875049B1 (en) | 2012-07-18 | 2018-12-26 | Institut National de la Sante et de la Recherche Medicale (INSERM) | Methods for preventing and treating chronic kidney disease (ckd) |
WO2014136910A1 (ja) | 2013-03-08 | 2014-09-12 | 国立大学法人大阪大学 | ペリオスチンのExon-21部位によりコードされるペプチドに対する抗体及び該抗体を含む炎症関連疾患の予防又は治療用医薬組成物 |
RU2016135417A (ru) * | 2014-02-07 | 2018-03-12 | МЕДИММЬЮН, ЭлЭлСи | Новый анализ для детектирования периостина человека |
JP7261482B2 (ja) | 2018-01-25 | 2023-04-20 | 国立大学法人大阪大学 | ペリオスチンの発現量増加またはスプライシングバリアントの変化を伴う疾患の治療用医薬組成物 |
JP7475584B2 (ja) * | 2019-05-10 | 2024-04-30 | 株式会社シノテスト | 免疫グロブリンaに結合しているペリオスチン並びに免疫グロブリンaに結合しているペリオスチンに結合する抗体、ペリオスチンの測定方法、ペリオスチンの測定試薬及びペリオスチン測定の正確性の改善方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0710719B1 (en) | 1990-01-12 | 2007-03-14 | Amgen Fremont Inc. | Generation of xenogeneic antibodies |
WO1994025585A1 (en) | 1993-04-26 | 1994-11-10 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
DE69133476T2 (de) | 1990-08-29 | 2006-01-05 | GenPharm International, Inc., Palo Alto | Transgene Mäuse fähig zur Produktion heterologer Antikörper |
JPH05268982A (ja) | 1992-03-27 | 1993-10-19 | Hoechst Japan Ltd | 骨形成作用を有する新規な蛋白質およびその製造法 |
JP4534092B2 (ja) | 2000-09-08 | 2010-09-01 | 第一三共株式会社 | 心不全治療剤 |
JP2007504842A (ja) * | 2003-05-29 | 2007-03-08 | ミレニアム ファーマシューティカルズ, インコーポレイテッド | 乳癌の同定、評価、予防、および治療のための組成物、キットおよび方法 |
WO2005019471A2 (en) * | 2003-08-13 | 2005-03-03 | Temple University Of The Commonwealth System Of Higher Education | Periostin-like factor: compositions and methods for making and using the same |
-
2006
- 2006-12-28 RU RU2008130898/13A patent/RU2008130898A/ru not_active Application Discontinuation
- 2006-12-28 AU AU2006334029A patent/AU2006334029B2/en active Active
- 2006-12-28 EP EP06843658.3A patent/EP1978034B2/en active Active
- 2006-12-28 BR BRPI0620747-2A patent/BRPI0620747A2/pt not_active IP Right Cessation
- 2006-12-28 JP JP2007552991A patent/JP5019464B2/ja active Active
- 2006-12-28 CN CNA2006800533635A patent/CN101389656A/zh active Pending
- 2006-12-28 CA CA2635849A patent/CA2635849C/en active Active
- 2006-12-28 WO PCT/JP2006/326280 patent/WO2007077934A1/ja active Application Filing
- 2006-12-28 KR KR1020087018312A patent/KR101363695B1/ko active Active
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103688171A (zh) * | 2010-12-16 | 2014-03-26 | 弗·哈夫曼-拉罗切有限公司 | 与th2抑制相关的诊断和治疗 |
CN105169390A (zh) * | 2010-12-16 | 2015-12-23 | 弗·哈夫曼-拉罗切有限公司 | 与th2抑制相关的诊断和治疗 |
CN112168962A (zh) * | 2010-12-16 | 2021-01-05 | 弗·哈夫曼-拉罗切有限公司 | 与th2抑制相关的诊断和治疗 |
CN114364400A (zh) * | 2019-09-11 | 2022-04-15 | 勃林格殷格翰国际加拿大公司 | 使用pd-1轴抑制剂及抗骨膜蛋白抗体治疗癌症的方法 |
WO2023036305A1 (zh) * | 2021-09-13 | 2023-03-16 | 沈阳眼产业技术研究院有限公司 | 抗periostin人源化单克隆抗体及其制备方法与应用 |
Also Published As
Publication number | Publication date |
---|---|
WO2007077934A1 (ja) | 2007-07-12 |
JPWO2007077934A1 (ja) | 2009-06-11 |
EP1978034A4 (en) | 2010-09-01 |
KR20080099248A (ko) | 2008-11-12 |
JP5019464B2 (ja) | 2012-09-05 |
RU2008130898A (ru) | 2010-02-10 |
EP1978034B2 (en) | 2018-05-16 |
AU2006334029B2 (en) | 2013-01-31 |
EP1978034B1 (en) | 2014-09-17 |
CA2635849A1 (en) | 2007-07-12 |
BRPI0620747A2 (pt) | 2011-11-22 |
AU2006334029A1 (en) | 2007-07-12 |
EP1978034A1 (en) | 2008-10-08 |
CA2635849C (en) | 2017-05-09 |
KR101363695B1 (ko) | 2014-02-14 |
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Owner name: SANKYO CO. Free format text: FORMER OWNER: ASUBIO PHARMA CO., LTD. Effective date: 20100907 |
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Effective date of registration: 20100907 Address after: Tokyo, Japan Applicant after: Sankyo Co. Co-applicant after: National University Corporation Osaka University Address before: Tokyo, Japan Applicant before: Asubio Pharma Co., Ltd. Co-applicant before: National University Corporation Osaka University |
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Application publication date: 20090318 |