CN101370553B - 用于单针体内电穿孔的装置和方法 - Google Patents

用于单针体内电穿孔的装置和方法 Download PDF

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Publication number
CN101370553B
CN101370553B CN2007800023139A CN200780002313A CN101370553B CN 101370553 B CN101370553 B CN 101370553B CN 2007800023139 A CN2007800023139 A CN 2007800023139A CN 200780002313 A CN200780002313 A CN 200780002313A CN 101370553 B CN101370553 B CN 101370553B
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China
Prior art keywords
needle
tissue
electrode
electroporation
electrodes
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Chinese (zh)
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CN101370553A (zh
Inventor
鲁内·谢肯
雅各布·马蒂森
托伦·伊丽莎白·谢尔勒
乔治·麦克休
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Inovio Pharmaceuticals Inc
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Genetronics Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Electrotherapy Devices (AREA)
  • Finger-Pressure Massage (AREA)
CN2007800023139A 2006-02-11 2007-02-09 用于单针体内电穿孔的装置和方法 Active CN101370553B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77225506P 2006-02-11 2006-02-11
US60/772,255 2006-02-11
PCT/US2007/003615 WO2007095140A2 (en) 2006-02-11 2007-02-09 Device and method for single-needle in vivo electroporation

Publications (2)

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CN101370553A CN101370553A (zh) 2009-02-18
CN101370553B true CN101370553B (zh) 2013-04-10

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CN2007800023139A Active CN101370553B (zh) 2006-02-11 2007-02-09 用于单针体内电穿孔的装置和方法

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US (3) US10369359B2 (https=)
EP (1) EP1981581B1 (https=)
JP (1) JP5059786B2 (https=)
KR (1) KR101385865B1 (https=)
CN (1) CN101370553B (https=)
AU (1) AU2007215263B2 (https=)
CA (2) CA3063263C (https=)
EA (1) EA200870252A1 (https=)
NO (1) NO340500B1 (https=)
WO (1) WO2007095140A2 (https=)

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Also Published As

Publication number Publication date
EP1981581A4 (en) 2011-05-25
US11331479B2 (en) 2022-05-17
US20070287950A1 (en) 2007-12-13
JP5059786B2 (ja) 2012-10-31
CA2635437A1 (en) 2007-08-23
CA2635437C (en) 2020-01-28
KR20080110988A (ko) 2008-12-22
US10369359B2 (en) 2019-08-06
WO2007095140A2 (en) 2007-08-23
CN101370553A (zh) 2009-02-18
NO340500B1 (no) 2017-05-02
US20230001190A1 (en) 2023-01-05
CA3063263A1 (en) 2007-08-23
AU2007215263B2 (en) 2011-07-07
WO2007095140A3 (en) 2008-01-10
EP1981581A2 (en) 2008-10-22
CA3063263C (en) 2024-01-16
EP1981581B1 (en) 2016-04-13
US20200001076A1 (en) 2020-01-02
JP2009525829A (ja) 2009-07-16
KR101385865B1 (ko) 2014-04-17
NO20083811L (no) 2008-09-05
EA200870252A1 (ru) 2009-02-27
AU2007215263A1 (en) 2007-08-23

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Effective date of registration: 20181218

Address after: American Pennsylvania

Patentee after: INOVIO PHARMACEUTICALS, Inc.

Address before: California, USA

Patentee before: GENETRONICS, Inc.

EE01 Entry into force of recordation of patent licensing contract
EE01 Entry into force of recordation of patent licensing contract

Application publication date: 20090218

Assignee: Beijing Apollo Saturn Biomedical Technology Co.,Ltd.

Assignor: INOVIO PHARMACEUTICALS, Inc.

Contract record no.: X2022990000903

Denomination of invention: Apparatus and method for single needle body electroporation

Granted publication date: 20130410

License type: Exclusive License

Record date: 20221108