CN101327325A - 眼科冲洗液及方法 - Google Patents

眼科冲洗液及方法 Download PDF

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Publication number
CN101327325A
CN101327325A CNA2008101376172A CN200810137617A CN101327325A CN 101327325 A CN101327325 A CN 101327325A CN A2008101376172 A CNA2008101376172 A CN A2008101376172A CN 200810137617 A CN200810137617 A CN 200810137617A CN 101327325 A CN101327325 A CN 101327325A
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China
Prior art keywords
solution
medicine
select
analgesic
iop
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CNA2008101376172A
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Chinese (zh)
Inventor
G·A·德莫普洛斯
P·P·帕尔默
J·M·赫尔茨
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Omeros Corp
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Omeros Medical Systems Inc
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Application filed by Omeros Medical Systems Inc filed Critical Omeros Medical Systems Inc
Publication of CN101327325A publication Critical patent/CN101327325A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
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    • A61P27/08—Mydriatics or cycloplegics
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CNA2008101376172A 2002-07-30 2003-07-30 眼科冲洗液及方法 Pending CN101327325A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39989902P 2002-07-30 2002-07-30
US60/399899 2002-07-30

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN038233452A Division CN1684701B (zh) 2002-07-30 2003-07-30 眼科冲洗液及方法

Publications (1)

Publication Number Publication Date
CN101327325A true CN101327325A (zh) 2008-12-24

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ID=31188639

Family Applications (3)

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CNA2008101376172A Pending CN101327325A (zh) 2002-07-30 2003-07-30 眼科冲洗液及方法
CN2012103206331A Pending CN103143022A (zh) 2002-07-30 2003-07-30 眼科冲洗液及方法
CN038233452A Expired - Lifetime CN1684701B (zh) 2002-07-30 2003-07-30 眼科冲洗液及方法

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CN2012103206331A Pending CN103143022A (zh) 2002-07-30 2003-07-30 眼科冲洗液及方法
CN038233452A Expired - Lifetime CN1684701B (zh) 2002-07-30 2003-07-30 眼科冲洗液及方法

Country Status (17)

Country Link
US (10) US20040072809A1 (enExample)
EP (1) EP1534313B1 (enExample)
JP (11) JP2006504661A (enExample)
CN (3) CN101327325A (enExample)
AU (2) AU2003261304A1 (enExample)
BE (1) BE2015C078I2 (enExample)
CA (2) CA2866848C (enExample)
CY (1) CY2015055I1 (enExample)
DK (1) DK1534313T3 (enExample)
ES (1) ES2397574T3 (enExample)
FR (1) FR15C0090I2 (enExample)
HU (1) HUS1500069I1 (enExample)
LU (1) LU92923I2 (enExample)
NL (1) NL300784I2 (enExample)
PT (1) PT1534313E (enExample)
SI (1) SI1534313T1 (enExample)
WO (1) WO2004010894A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104822265A (zh) * 2012-10-24 2015-08-05 奥默罗斯公司 稳定的不含防腐剂的瞳孔散大剂和用于注射的抗炎溶液
CN104856990A (zh) * 2015-05-07 2015-08-26 武汉武药科技有限公司 去氧肾上腺素酮咯酸溶液及制备方法
US11234965B2 (en) 2014-12-01 2022-02-01 Omeros Corporation Anti-inflammatory and mydriatic intracameral solutions for inhibition of postoperative ocular inflammatory conditions

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US8748402B2 (en) 2004-06-07 2014-06-10 Bausch & Lomb Pharma Holdings Corp. Ophthalmic formulations and uses thereof
US7919094B2 (en) 2004-06-10 2011-04-05 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
CA2847677C (en) 2004-06-10 2018-05-01 Omeros Corporation Methods for treating conditions associated with masp-2 dependent complement activation
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US20070048389A1 (en) * 2005-08-26 2007-03-01 Fu-Pao Tsao Stabilized and preserved ketotifen ophthalmic compositions
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WO2008077712A1 (en) * 2006-12-22 2008-07-03 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Gel useful for the delivery of ophthalmic drugs
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CN101347620B (zh) * 2007-07-20 2012-04-25 天津药业研究院有限公司 一种药物组合物及其在制备治疗青光眼的药物中的应用
CN102196819B (zh) 2008-10-30 2013-01-30 国立大学法人冈山大学 局部麻醉用组合物
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KR20220044616A (ko) 2011-04-08 2022-04-08 유니버시티 오브 레스터 Ｍａｓｐ-2 의존적 보체 활성화와 관련된 질병을 치료하는 방법
US9644035B2 (en) 2011-04-08 2017-05-09 Omeros Corporation Methods for treating conditions associated with MASP-2 dependent complement activation
US9504691B2 (en) * 2012-12-06 2016-11-29 Alcon Research, Ltd. Finafloxacin suspension compositions
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CN105213418B (zh) * 2015-11-11 2019-01-22 中国人民解放军第四军医大学 一种眼科术前用复方滴眼液及其制备方法
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JP7123932B2 (ja) * 2016-09-02 2022-08-23 クリストファー ジェイ． ソアレス 神経保護及び神経疾患におけるｃｇｒｐ受容体アンタゴニストの使用
US20180318319A1 (en) 2017-05-04 2018-11-08 Ocular Science, Inc. Compositions and Methods for Treating Eyes and Methods of Preparation
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KR20200018580A (ko) * 2017-06-08 2020-02-19 아이 쎄러피스 엘엘씨 저용량 브리모니딘 조합 및 그의 용도
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