CN101322555A - Tibetan medicine Aili yuan-invigorating capsules - Google Patents

Tibetan medicine Aili yuan-invigorating capsules Download PDF

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CN101322555A
CN101322555A CNA2008101286392A CN200810128639A CN101322555A CN 101322555 A CN101322555 A CN 101322555A CN A2008101286392 A CNA2008101286392 A CN A2008101286392A CN 200810128639 A CN200810128639 A CN 200810128639A CN 101322555 A CN101322555 A CN 101322555A
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CN101322555B (en
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苟春虎
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Qinghai Technology Development Co Ltd Connaught Blue Qi
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Abstract

The invention belongs to the filed of health care foods, in particular to a hard capsule which is prepared by Tibetan caterpillar fungus extract, Tibetan lamb placenta, Tibetan wolfberry extract, Tibetan sea royal jelly extract, Tibetan songaria cynomorium herb extract, Tibetan rhizome extract, Tibetan membranous milkvetch root extract, Tibetan deer-horn gelatin extract, puncturevine caltrop fruit extract, yohimbine, ginkgo biloba extract, arginine and other raw materials, the production process of the capsule is as follows: an official product is prepared by preparing, mixing, stirring, capsule filling, capsule sealing, inspection and packaging, and the product contains Tibetan caterpillar fungus extract, Tibetan lamb placenta, Tibetan wolfberry extract, Tibetan sea royal jelly extract, Tibetan songaria cynomorium herb extract, Tibetan rhizome extract, Tibetan membranous milkvetch root extract, Tibetan deer-horn gelatin extract, puncturevine caltrop fruit extract, yohimbine, ginkgo biloba extract, arginine and other raw materials. The hard capsule has the effects of preventing and treating erectile dysfunction, sexual dysfunction and lacking in sexual interest, etc.

Description

Tibetan medicine Aili yuan-invigorating capsules
One, technical field:
The invention belongs to health food, relate in particular to health food to hide raw materials such as Cordyceps, Tibet sheep placenta, Tibetan wolfberry fruit extract, Qinghai royal jelly extract, Tibetan Herba Cynomorii extract, Tibetan Rhizoma Polygonati extract, Tibetan Astragalus Root P.E, Tibetan Colla cornus cervi extract, Yohimbine, ginkgo biloba extract, tribulus fruit extract, arginine, to take advanced technologies to process.
Two, background technology:
The present invention is to hide Cordyceps, Tibet sheep placenta, Tibetan wolfberry fruit extract, Qinghai royal jelly extract, hide Herba Cynomorii extract, hide Rhizoma Polygonati extract, hide Astragalus Root P.E, to hide the hard shell capsules that raw materials such as Colla cornus cervi extract, Yohimbine, ginkgo biloba extract, tribulus fruit extract, arginine are made, effective, there is not any peculiar smell, taking convenience has effects such as the impotence of control, sex dysfunction, frigidity.
Three, summary of the invention:
Male sexual disfunction is the common disease of adult male, and along with accelerating development of society, people's live and work pressure strengthens, and its virile diesae also presents ascendant trend.In the whole nation more than 300,000,000 among the male sex adult, there are 8,000 ten thousand male sex nearly to suffer from various degree sex dysfunction, 40-50 year crowd and being engaged in mental work for a long time especially, nerve is in the middle age of anxiety, is the high risk group family of sex dysfunction.This product aims at a kind of Tibetan medicine health food of this high risk group development.This series products is not also in the market developed this product and be can be and provide a kind of novel healthy food to impotence, sex dysfunction, sexless patient.
Four, composition of raw materials: hide Cordyceps 1-5 kilogram, Tibet sheep placenta 4-8 kilogram, hide wolfberry fruit extract 5-10 kilogram, Qinghai royal jelly extract 2-5 kilogram is hidden Herba Cynomorii extract 3-6 kilogram, hide Rhizoma Polygonati extract 1-4 kilogram, hide Astragalus Root P.E 1-4 kilogram, hide Colla cornus cervi extract 1-3 kilogram, Yohimbine 0.3-0.6 kilogram, ginkgo biloba extract 0.6-1 kilogram, tribulus fruit extract, arginine 10-15 kilogram.
Five, technical scheme:
(1), hide Cordyceps extract (Chinese caterpillar fungus): being to be grown in a kind of microorganism (fungus body) under the Qinghai-Tibet 3500-4500 rice particular surroundings, is that China's Tibetan medicine is protected the medicinal material of Chinese medicine simply in the storehouse.In global Chinese, there is widely U.S.A transcribe, Chinese caterpillar fungus is always regarded as the panacea of treatment weakness by common people, be (Chinese caterpillar fungus, pilose antler, genseng) first of the Chinese herbal medicine " three mend ", enjoy the good name of " the east legend are very precious " in the world and be described as disease-resistant anti-cancer to good Chinese medicine, bring the world health by the expert.
Chinese caterpillar fungus is an ergot composite family fungi Cordyceps Militaris, colonizes in the stroma on the Hepialidae insect larvae and the complex of larva corpse.Warm in nature, the flavor sweet, return kidney, lung channel.Have nourishing lung and kidney, mend smart marrow, Yin Yang balancing, hemostasis and phlegm, the function of delaying senility of giving birth to.To cancer-resisting, anaemia weakness, hepatitis B, raising immune function of human body work the effect of consolidating.
Chemical composition: Chinese caterpillar fungus contains saponins, cordycepic acid, Cordyceps sinensis polysaccharide, superoxide dismutase various active goods and materials such as (SOD), and amino acid, vitamin and trace element, selenium, calcium, potassium, manganese, zinc etc.
Pharmacological action: 1, regulate immunologic function: (1) is to the humidification of monokaryon one macrophage system function: Cordyceps Militaris water extract can obviously improve colloid carbon particle clearance degree in the mouse blood, to the mouse monokaryon phagocyte, peritoneal macrophage, phagocytic functions such as reticuloendothelial system have tangible activation.It is bright to engulf test card in the body, and this product can significantly improve the phagocytic function of Turnover of Mouse Peritoneal Macrophages.
(2) to the influence of body immunity: Cordyceps Militaris and Cordyceps sinensis polysaccharide can make mice serum 1gE content obviously increase, and have improved the serum hemolysin level, induce splenocyte to express the IL-2 acceptor.
(3) increase NK (NK) activity: studies show that the administration of Chinese caterpillar fungus alcohol extracting liquid can obviously strengthen the killing activity of the inside and outside NK pair cell of mouse body.
2, tonifying kidney and strengthening yang: Chinese caterpillar fungus can be regulated renal function, and tonifying yin is yang-tonifying again, and is not empty not high, reinvigoration, the strong kidney of help.But Chinese caterpillar fungus also has male sex hormone effect production of sperm, and to impotence and seminal emission, the disease of the insufficiency of the kidney yang of soreness of waist and knee joint is effective in cure.
3, adjusting sexual function: Chinese caterpillar fungus has certain androgen-like action, can make the weightening finish of castration male rat childhood seminal vesicle.Male mouse blood plasma cortisol content is increased for mouse stomach, the adrenal gland cholesterol is increased, the adrenal gland weightening finish has preventive and therapeutic effect to " deficiency of yang type " due to the oxidation cortisone, and sexual dysfunction is had the adjusting restitution.In addition, Chinese caterpillar fungus also has the synthetic and secretion that promotes and strengthen cortex hormone of aadrenaline.
4, anti-ageing: Chinese caterpillar fungus can alleviate the infringement to the body biochemical process that descends and cause thus owing to the old and feeble maincenter catecholamine levels that causes, and removes human body harmful's free radical, delays senility the effect of good health and a long life thereby play.Anti-ageing result of the test shows, the Cordyceps sinensis polysaccharide of separate sources all has in various degree prolongation effect to life span of drosophila melanogaster, thereby the proof Cordyceps sinensis polysaccharide has function in delaying senility.
5, anti-oxidant: Chinese caterpillar fungus can suppress lipid peroxidation and generate; Strengthen red blood cell hepatocuprein vigor.Cordyceps Militaris can suppress MDA in rat, the mouse brain.According to another report, TaiWan, China ancient Chinese name for Venus hospital carries out human trial to the nephrotic, finds to take Chinese caterpillar fungus after 1 month, and tangible anti-oxidant reaction is arranged in the blood.
6, beautifying face and moistering lotion: in present medical circle, in the confessed seven big class anti-aging beauty-care active components, Chinese caterpillar fungus just contains five big classes, is respectively polysaccharide, amino acid, polypeptide (protein), nucleic acid and vitamin (other two big flavonoids and soap class).Chinese caterpillar fungus also has the adjusting endocrine, and tangible calmness and syngignoscism are arranged, and has the beautifying face and moistering lotion effect.
7, treatment cardiovascular disease, strengthen cardio and vascular function: Chinese caterpillar fungus has the adjusting cardio and vascular function, has hypotensive, reducing blood lipid and reduction MCO improve cardiac muscle and cerebral anoxia, anti-arrhythmia, antifatigue and the anti-ageing effect of waiting for a long time make the running of cardiovascular and cerebrovascular normal health.
8, antitumor: Chinese caterpillar fungus has the synthetic function of human activin DNA, can strengthen autoimmunity, and leucocyte is engulfed the oncocyte encirclement of the bad sex change of human body and produced normal cell, oncocyte is reduced or disappearance, and tumour also can slowly be contracted to disappearance.The Chinese caterpillar fungus water decoction has certain inhibitory action to mouse S180.Antitumous effect to Ismipur has humidification, and the growth of mouse subcutaneous transplanting lung knurl is had the obvious suppression effect.According to another report, Chinese caterpillar fungus mouse entity S180 knurl etc. is had inhibitory action, intravenous effect is 100%.The average inhibitory rate 45.71% of report is also arranged.
Cordyceps sinensis polysaccharide: have anticancer and immunosuppressive action: with lotus knurl BALB/C is that model is observed Cordyceps sinensis polysaccharide and can obviously be suppressed tumor growth. studies show that, Cordyceps sinensis polysaccharide can activate phagocytic function and DTH reaction, directly or indirectly discharge the cytotoxic factor killing tumor cell, suppress tumor growth, prove that Cordyceps sinensis polysaccharide has obvious antineoplastic.
9, protect the liver: Chinese caterpillar fungus has improves the effect that chronic type b, viral hepatitis type C symptom have the virus removed.Surface antigen is turned out cloudy; make liver function recovery normal; reach the effect for the treatment of both principal and secondary aspect of disease; according to another report; cordyceps sinensis polysaccharide liposome (CPL) can significantly reduce the activity of ALT and AST in the hepatic injury mice serum; murine liver tissue, pathological section show, the CPL of senior middle school's agent has protective effect to the CPL that the mouse liver injury due to amino half sugar of D-and middle agent are to the hepatic injury due to four carbonoxides.The prompting Chinese caterpillar fungus has function for protecting liver and reducing enzyme activity.Chinese caterpillar fungus has certain preventive and therapeutic effect to hepatitis B in addition.
10, strengthen the cardiac pulse ability, cordyceps mycelia extract 100ug/ml can obviously strengthen the active contraction intensity of rat in the atrium, prolongs ST.
11, antifatigue, high temperature resistant, anti-anoxic: with cordyceps mycelia extract 100-200mg/kg mouse swimming test, the result proves that swimming time prolongs, and has the resistivity that strengthens under muscle power and the stressed condition.Chinese caterpillar fungus group mouse stomach has the high temperature resistant effect of obvious anti-fatigue.The lumbar injection Chinese caterpillar fungus has the increase resisting oxygen lack.
It is reported that the double-blind trial of Medical School of Peking University confirms, Chinese caterpillar fungus far surpasses genseng in the lifting of physical efficiency and explosive force, the Chinese female player who in 1993 and Olympic Games Women's 1000m in 1994 race, wins the title, to make finish the full distance in 42 seconds of whole world motion circle shock with breaking a record. its reason is that the sportsman takes Cordyceps for a long time, to promote explosive force, so the health effect of Chinese caterpillar fungus is subjected to attracting attention of west biochemical medicine circle.
12, hypotensive, reducing blood lipid: the factor that causes angiocardiopathy is a lot, but mainly is that blood fat increases and causes artery sclerosis to cause, therefore controlling hyperlipemia disease just becomes the key of preventing and treating angiocardiopathy.Chinese caterpillar fungus confirms through the clinical observation of strictness, and serum total cholesterol (CT) concentration, serum triglyceride (TG) concentration are significantly descended, have significantly hypotensive, the effect of reducing blood lipid.
13, hypoglycemic: the CHWC polysaccharide in the Chinese caterpillar fungus thalline, lumbar injection 50mg/kg has significant hypoglycemic activity, onset in 3 hours.To the alloxan diabetes model mice, the obvious functions of blood sugar effect is arranged, descend about 40% than control group.
14, antiasthmatic-antitussive has better curative effect to pulmonary emphysema, tracheitis: be the common respiratory tract infection of respiratory disease spring, pulmonary infection, disease such as chronic cough, asthma, because its clinical shape is to influenza and for similar, a lot of people do not attract great attention, thus delay treatment.Clearing lung-heat good medicine Chinese caterpillar fungus is discharged by the guiding fester, removes outmoded phlegm piece, nourishes lung tissue, the activate immunity function is removed respiratory disorder, will effect a permanent cure, consolidates, nourish and combine, fundamentally improve lung functions, recover the mucous membrane activity, improve immunologic function.
The also expansible bronchial smooth muscle of Chinese caterpillar fungus strengthens adrenaline, and to the lung qi loss, the lung power consumption hinders that void is breathed heavily, the disease of phthisical cough phlegm blood has a significant effect.It is relevant with deficiency of both the lung and kidney that the traditional Chinese medical science thinks that old-slow-bronchial tube is sent out the people repeatedly.Chinese caterpillar fungus is warm in nature, mends the lean marrow, nourishing lung and kidney, and this thing is protected lung qi." from the new compilation of materia medica " record, Chinese caterpillar fungus protects the lung kidney-nourishing, and hemostasis and phlegm ends the phthisical cough effect.Its nature and flavor, sweet, warm, go into lung, kidney channel.But it is bright to go into the lung tonifying lung, and following kidney is qi-restoratives the moon then, has beneficial lung and protects lung, relieving cough and reducing sputum, and the hemostasis qi-restoratives decreases, effects such as strong vital essence.Be usually used in treating that chronic cough void is breathed heavily, phthisical cough spitting of blood, the moon are withered, seminal emission, soreness of waist and knee joint etc.The chronic cough void that the treatment old-slow-bronchial tube causes is breathed heavily.
15, qi-restoratives, the postoperative rehabilitation effect, Chinese caterpillar fungus has anticancer, antiviral special efficacy, Cordyceps sinensis polysaccharide has strengthening the body resistance to consolidate the constitution, improves the effect of immunologic function, contains abundant vitamin and selenium element in the Chinese caterpillar fungus; Can both strengthen body immune system, build up resistance.Patient has consumed a large amount of nutriments during sick, take the nutritional labeling that Chinese caterpillar fungus just in time can be replenished the various urgent needs of body this moment, recovers patient's muscle power, and is very favourable to physical rehabilitation.Postoperative patient has a delicate constitution, and resists the virus attack ability and obviously reduces, and nutrition goods and materials such as a large amount of protein and vitamin also are badly in need of in wound healing.Protein content is repaired damaged tissues in the Chinese caterpillar fungus up to 27.81% pair, and recovering physique has tangible effect.
16, strengthen memory: contained nucleic acid bioactive ingredients in the Chinese caterpillar fungus, edible back is found, the increase of hemoglobin and oxygen affinity helps supplying with cerebral tissue, the cell oxygen carrying content increases, thereby eliminate the tired and raising ability of learning and memory that brain is not enough because of oxygen supply and shortage nutrition causes.According to another report, Japanology finds that nucleotide pair ischemic nerve cell has protective effect.The mouse brain cell mortality that found that diet nucleotides is fewer.Experiment showed, edible nucleotide pair ischemic, nerve cell has protective effect, takes nucleotides and shows in zoopery and can prevention of brain block.
(2), Tibet sheep placenta (sheep ' s), (sheep placenta extracts).Be conceived 3-5 month sheep embryo of tibetan sheep, utilize biotechnology to extract biological activity.China's tradition traditional Chinese medicine is to animal placenta application history for a long time.According to Compendium of Materia Medica record, sheep placenta disposition temperature, sweet-salty.Effect with kidney tonifying, replenishing essence, benefiting qi and nourishing blood.The clinical men and women's of being used for consumptive disease, neurasthenia, qi-blood deficiency, spiritlessness and weakness, prolonged illness loss, spontaneous sweating, sexual disorder and endocrinopathy are caused a disease all effective in cure.The traditional Chinese medical science is thought tonifying Qi, nourish blood, replenishing vital essence function.Be used for impotence, seminal emission, women's insufficiency of vital energy and blood and infertile, few breast etc.Modern medicine study, the sheep placenta element is a kind of polypeptide protein material or perhaps the living cells thing that extracts from conceived sheep placenta dish, but this material activating human body skin and tracheae function, effectively promote body metabolism, strengthen immunity of organisms, promote human tissue cell's division, strengthen cytoactive, strengthen the Skin Cell power of regeneration, removing beverage, wrinkle-chasing, enhancing skin elasticity and gloss, delay youth, skin whitening, anti-ageing, relieving mental strain and helping sleep, improve memory, eliminate fatigue etc.
Chemical analysis: 1, steroid hormone: have that multiple steroid is bright, an androsterone, estradiol, estriol, oestrone.2, placental hormone: promoting sexual gland hormone A, promoting sexual gland hormone B, lactogen, thyrotropic hormone, human chorionic gonadtropin, corticotropin etc.3, enzyme: kininase oxytocinase, lysozyme, ball egg folding enzyme, hyaluronidase etc. are arranged.Contain DNA and nucleic acid, polypeptide protein, ten several amino acids, glutinous polysaccharide, lecithin, B.Family vitamin etc.Can produce various adjusting peptides, growth factor, cell factor, nucleic acid etc. rapidly according to external report sheep placenta element, and the active factors with superpower dna replication dna ability.
Pharmacological action: 1, anti-oxidant: the sheep placenta element was to 20 months healthy geriatric rat 150mg/kg every day body weight, 300mg/kg, 600mg/kg per os award the sheep placenta cellulose solution, after 80 days, measure respectively and respectively organize superoxide dismutase (SOD), MDA (MDA), monoamine oxidase (MAO) in rat red blood cell and the tissue.The sheep placenta element SOD content in the old rats red blood cell that can obviously raise reduces MAD content in serum and the hepatic tissue, and reduces brain tissue MAO vigor, so the sheep placenta element has antioxidation to old rats as a result.
It is reported that the foreign study experiment shows that (1) fruit bat average life span increases by 17.7%, human body is taken 15 days experimenter's lipid peroxides and is descended, and superoxide dismutase (SOD) value rises, and illustrating has positive effect to human body MDA (MDA), SOD.(2) rat blood serum and liver MDA descend 15%, and lipid oxide is had inhibitory action.(3) rat blood serum SOD raises 9.63%, and the manganese antioxidase raises 33.13%.
2, anti-ageing: the sheep placenta element has the irritation cell power of regeneration, delays senility.It is reported, sheep placenta is plain and umbilical cord contains embryonic stem cell and adult stem cell, these active components have face nourishing antidebilitation and act on always.
3, strengthen immunity; Studies show that, the sheep placenta element compares mouse nospecific immunity and specific immune function index analysis, the phagocytic function of thymus gland, index and spleen index and the mononuclear macrophage of the plain high dose group of sheep placenta, low dose group all obviously improves, the conversion reaction of SPL strengthens, serum hemolysin generation value also increases, so think that the sheep placenta element has the effect that improves the mouse body's immunity.
4, regulate endocrine: the sheep placenta element has obvious effects to regulating the hormone secretion function, can improve human body hormone secretion level, the aging of delaying female ovary, changes the ovary function, prevents climacteric obstacle, physiological change.
5, beautifying face and moistering lotion: studies show that, contain a series of micromolecule polypeptides such as peculiar superpower biologically active SF and BF in the sheep placenta element, its relative molecular weight is 3800-5000, it can activate Skin Cell regeneration, make it to breed degree of progress speed, activation skin surface tissue, removing also stops harmful oxide to be accumulated and melanocyte formation melanosome, color spot can't be formed, keep skin-whitening, promote elastin laminin cell proliferation, make the skin reticular fiber structure become closely flexible, keep moisture of skin to be difficult for running off and replenish skin-nourishing comprehensively, the balance skin metabolism is eliminated pachylosis, dry and cracked phenomenon makes skin become tender and lovely.Therefore the sheep placenta element has just enjoyed the women to welcome since coming out.
6, smooth away wrinkles: the sheep placenta element can promote elastin laminin cell proliferation, makes the skin reticular fiber structure become closely flexible, makes moisture be difficult for running off, and replenishes skin-nourishing comprehensively.According to another report, the loose wrinkling reason of the skin influence that is free radical.The sheep placenta element has the effect of oxidation and removing free radicals, can dispel facial wrinkles.In addition sheep placenta have nourish blood, invigorate blood circulation, regulating menoxenias such as cool blood and blood, can make blood engorgement skin, be that skin obtains enough nutrition, can effectively dispel wrinkle and delay wrinkle and produce too early.
7, promote hematopoiesis, improve anaemia: research thinks, sheep placenta is plain can hematopoietic stimulation tissue, and promotion hematopoiesis has tangible anti-anaemia effect, and the effect of rising red blood cell significantly promotes the marrow hemopoiesis function, improves the asthenia universalis symptom.
8, gonadotropic Effect: the sheep placenta element can promote the growth of women's secondary sex characters, promotes that endometrial hyperplasia is beneficial to embryo nidation and growth.According to another report, sheep placenta is plain gives lactation young rabbit injection, has the effect that promotes its growth, can significantly promote the growth of thymus gland, spleen, uterus, vagina, mammary gland; Thyroid gland, testis also there is the growth of promotion effect.
(3), hide matrimony vine (LyciUm barbarnm extraat), the fruit of Chinese wolfberry is the sub-ripening fruits of matrimony vine of solanaceae plant.The property flat, flavor is sweet.Have by the liver kidney, promoting vital essence and blood genernation makes eye bright, moistening lung, beauty treatment, functions such as fat-reducing.
Chemical composition: fruit of Chinese wolfberry main component has polysaccharide, amino acid, sweet theophylline, carrotene, vitamin B1, vitamin B2, various trace elements such as multivitamin such as vitamin C, nicotinic acid and manganese, chromium, zinc, copper, magnesium, calcium, germanium, cobalt, iron.
Pharmacological action: 1, protection birth-death system it is reported research of HSPH of Wuhan University
Achievement shows that LBP-X can produce protective effect to the reproductive system that is damaged by effect " HPG " this axis.
Experiment shows that LBP-X promotes hypophysis secretion gonadal hormone by the gonadotropic hormone effect, and " HPG " this axis is produced the multilayer regulating action, impels the production of sperm process unimpeded normal with the growth of testis reproduction cell.
2, improve sexual function: the fruit of Chinese wolfberry has filling liver kidney, promoting vital essence and blood genernation, supporing yang function.No matter be that kidney-yang deficiency, kidney-yin deficiency all have certain effect, Fructus lycii P.E also has the effect of short gonad function, and plasma testosterone level is significantly raise, and property kinetic energy is gone down, and impotence plays an important role.
3, strengthen immunity: the fruit of Chinese wolfberry is a medicine-food two-purpose food, and fruit of Chinese wolfberry polysaccharide has enhancing immunity, and antitumor action can strengthen the cell anti-cancer function selectively.LBP-X can strengthen natural killer cell and lymphocyte vigor, promotes interleukin to generate, and strengthens monocytic immune vigor.Fruit of Chinese wolfberry polysaccharide also has antimutagenic effect, when mutagenesis produces genetic damage and cell mutation, can repair damaged cell and recover its normal function.
4, anti-ageing: the fruit of Chinese wolfberry has the rejuvenation effect, and showing as to stimulate sexual gland and endocrine, strengthens hormonal secretion, strengthens the physiological function of brain function and nerve cell.The toxin phenomenon occurs accumulating in the blood though can avoid people's age growth, thereby keep the normal function of in-vivo tissue.But fruit of Chinese wolfberry polysaccharide antagonism free radical peroxidase activity strengthen superoxide dismutase and glutathione peroxidase vigor, thereby the damage that alleviates the radical pair body has anti-ageing effect.
5, the plant of a kind of indomitable vitality of the fruit of Chinese wolfberry, the traditional Chinese medical science think that taking the fruit of Chinese wolfberry can help human body to strengthen energy, nourishing liver and kidney, benefiting shrewd head, the increase immunity that nourishes blood, and the effect that the fruit of Chinese wolfberry adapts to most is exactly an antifatigue.Antifatigue: matrimony vine can be improved hydroxyproline concentration, thereby improves muscular strength, and fatigue capability is strengthened.
Six, protection liver: Fructus lycii P.E has certain effect to protecting liver and fatty liver.Reason is that matrimony vine contains a kind of active ingredient one sweet theophylline, and it is effective to the treatment liver.Pharmacological research shows that sweet theophylline has the fat of inhibition to deposit, and promotes the effect of liver cell regeneration in liver cell.Concerning the liver patient, the sweet theophylline in the fruit of Chinese wolfberry can prevent that fattiness stores in the liver, and lipotropic effect is arranged, and contained chlorophyll helps the liver detoxification effect in the matrimony vine, can also increase and improve liver function simultaneously.Chronic hepatitis patients, especially fatty liver patient.
7, reducing blood lipid: Fructus lycii P.E can reduce the rat cholesterol, and the cholesterol that can obviously suppress high cholesterol and the caused rabbit anteserum of lard feed increases.
8, hypoglycemic: wolfberry fruit extract can reduce rat blood sugar significantly enduringly, improves sugar tolerance.
9, control age-related macular degeneration: the fruit of Chinese wolfberry has the easypro liver effect that makes eye bright.To chronic hepatitis, central retinitis, optic atrophies etc. are evident in efficacy.Ageing disorders such as old organ senescence had very strong improvement effect.Discover that the fruit of Chinese wolfberry helps to reduce the generation of old degeneration maculopathy.
10, anti-apoptotic: Apoptosis is called apoptosis again.Interrelated data shows that brain normally has 10 nerve cell deaths every day approximately, and the human body new nerve cell of can not regenerating.When the fast a large amount of apoptosis of cell, early ageing, weak, film attenuation and atrophy can appear in the people, skin kraurosis, and with a haggard face, memory and thinking ability descend, even it is slow-witted old disease to occur.
Apoptosis except with occur outside the Pass pathology and inherent cause have, a large amount of apoptosis fast and two factors are closely-related; First free radical is made the oxidation reaction of use free radical with old and feeble closely related, causes that the free radical of cellular oxidation all can cause Apoptosis.Studies confirm that, " cerebroside ester, " that the fruit of Chinese wolfberry contains is that compound sugar combines formed glycosides with the ceramide terminal hydroxyl, owing to cerebroside ester is combined into by hydrophilic glycosyl and lipophilic ceramide, be one of important component of cell membrane, can keep cyto-architectural integrality.Simultaneously, cerebroside ester can form hydrogen bond network widely in biomembrane polarity and nonpolar interface.This is to constitute the constitutionally stable key factor of biomembrane stratiform.
According to another report, Ca2+ extensively raises in the thymocyte that LBP DEX capable of blocking induces, and suppresses the dna segmentization that DEX induces, and inhibitory action has dose dependent, its mechanism of action may pass through to reduce the wide concentration of cell C for LBP, suppresses the endonuclease enzyme activation, thus the blocking-up Apoptosis.
11, antitumor: the LBP-X combination with radiotherapeutic has certain radiosensitizing effect to acute weary oxygen tumour cell.LBP-X has in the non-specific antitumor and specificity antineoplastic process macrophage certain activation is all arranged.With S180 lotus knurl Bal6/C mouse is model, discover, LBP-X can recover and improve mice with tumor spleens cell number and activating T cell multiplication capacity, promotes the active and TNF secretion level of NK, and the prompting LBP-X can strengthen cellular immune function makes it suppress the dominant mechanism of tumor effect.
12, beauty treatment is preserved youthful looks: so the anti-ageing lipid that can suppress deposits in liver cell, promote liver cell new life's effect.Matrimony vine contains carotene, and compositions such as thiamine, riboflavin, Yan acid have moist skin, and the look of preserving youthful looks is the good merchantable brand of beauty treatment.The fruit of Chinese wolfberry can improve the ability to take oxygen of skin, can play the effect of skin whitening.
It is reported that Britain, French medical science man discover that the fruit of Chinese wolfberry contains a kind of vitamin of not meeting, and is named as " vitamin ", is also referred to as the vitamin of preserving youthful looks.So Fructus lycii P.E has extremely strong skin maintenance effect.
(4), hide royal jelly extract (LacRehis Apic), this product is the milky jelly and the formulated liquid of honey of the worker bee glandulae pharyngeae secretion of Apidae insect honeybee etc.The property flat, flavor is sweet, sour.
Chemical analysis: the fatty acids of royal jelly, sterols, protein, 18 seed amino acids, vitamin A, vitamin C, vitamin E, B family vitamin, folic acid, pantothenic acid, inositol, nicotinic acid, adenine nucleotides acid and adenosine, uridine, guanosine; Acid p'tase and alkaline phosphatase, enzymes such as cholinesterase.
Pharmacological action: 1, strengthen immunologic function: discover that edible royal jelly has three big functions to immune system: the one, balancing human body is regulated endocrine, thereby is stablized immune system.The 2nd, there is nature to remove function, can remove harmful substance in the human body, the protection immune system.Three provide comprehensive special nutrient, nutrition immune system.Therefore edible royal jelly can stimulate body to produce a large amount of antibody, significantly strengthens cellular immune function and humoral immune function, and marrow and lymphoid tissue and whole immune system are produced useful influence.Strengthen body's immunity.
2, delay senility: studies show that, royal jelly is by generally acknowledged " life longevity factor ", and it contains a large amount of protein of needed by human, and the haemocyanin that particularly plays an important role accounts for 2/3, globulin is about 1/3, and haemocyanin, globulin in this and the blood of human body are in similar proportion; The globulin that is contained is a kind of mixture of Y one globulin, has antibiotic, antiviral, function in delaying senility; 21 seed amino acids that contain; 8 kinds of essential amino acids wherein; The vitamin more than 16 kinds that the activity that contains is very strong, wherein the abundant acetylcholine of content can not only strengthen memory, and can delay senility.Also contain phosphate cpd in addition, various trace elements, enzyme, micro-hormone, peptide growth factor, these materials can promote cellular metabolism more all sidedly, division and regeneration.Old and feeble cell is upgraded, thereby make people's longevity.The agent of royal jelly nutritive composition is complete, can carry out comprehensive nutrition to human body, makes whole machine body obtain upgrading, thus delaying human body caducity.
3, enhancing sexual function: contain promoting sexual gland hormone in the royal jelly, can make the effect that the sexual centre youth is everlasting.Hypogona dism at first is that aging takes place sexual centre, influences reproductive organs, produces various sex dysfunction.Royal jelly can be had an effect at sexual centre, plays the effect that prevents sexual disorder and strengthen its function.Experiment is proof also, and royal jelly can also directly stimulate genitals and relevant organ to strengthen its function.Royal jelly has more significant effect aspect recovering and strengthening women's sexual function.Experimental result proves that royal jelly can improve sperm motility, and this is the cause that atriphos (ATP) and sugar have offered the sperm motility energy.
The foreign scholar once experimentized with the back 21 days mouse of birth in zoopery, find that royal jelly is accelerated its follicle maturity, and the promoting sexual gland hormone effect was proportional with injection royal jelly dosage.
According to another report, Japan medical science is discovered, contains a large amount of vegetalitas reproduction cell pollen in the royal jelly, and it is made up of a kind of and the similar plant hormone of the pituitrin people.The plant characteristic that significantly enlivens sexual gland is arranged.And the sugar of honey is very useful to the formation of seminal fluid very easily by blood absorption.The asparatate that contains in the royal jelly is the main matter of " helping property ", and it also has the growth of promotion, improves sexual function, stimulates fecundity.Strengthen Abwehrkraft des Koepers,, anti-senility active ingredient neural with hematopoiesis function and adjusting enhance metabolism.Because of weak, old hypogona dism person, can adhere to taking royal jelly.
4, anti-oxidant: modern study shows that royal jelly contains abundant superoxide dismutase (SOD), the co-factor of antioxidant reductases such as peroxidase antioxidases such as (CAT) and zinc, copper, manganese, and royal jelly also can significantly improve the SOD activity.Antioxidants such as the vitamin A that royal jelly also contains, C, E, B and trace elements of selenium have good antioxidation, avoid the infringement of free radical with the protection human body cell.
5, brain tonic and intelligence development: studies have shown that edible royal jelly can make brain obtain prescribing adequate nutrition, improve people's computing capability, thinking ability and tap intellectual resources.Particularly the academic dress before the examination with royal jelly after, feel that all the clever order of ear is intelligent, quick-minded, energetic, hypermnesia, biotonus also obviously relaxes.In a word, the royal jelly nutritive composition is comprehensive, balanced proportion, and the effect of its brain tonic and intelligence development not only is its distinctive composition, but the comprehensive function of its comprehensive nutrition.Often taking royal jelly can not only have good health and a long life, and brain tonic and intelligence development also is of great benefit to, and is the nutrition brain, improves the good merchantable brand of intelligence.
6, skin maintenance: royal jelly is a kind of natural high tonic, and it not only has medicinal health care function, also has skin care, and nutrition beautifies skin and prevention, treats dermopathic cosmetic result.By adjusting nursing skin from inside to outside, reach the effect of skin maintenance to the nourishing of whole body with to the inside of human body.
Why royal jelly can have the beautification function of mystery like this, theory of traditional Chinese medical science according to " in elegant outer must the supporting ", the analysis showed that, the protein that contains needed by human in the royal jelly, amino acid, vitamin, trace element, enzyme, lipid, carbohydrate, hormone, phosphate cpd etc., also have some unknown compositions, these abundant nutritions have the effect of beauty treatment, as contained peptide growth factor, can promote cellular metabolism, division and regeneration more all sidedly, making old and feeble cell is to replace in the new cell successive dynasties.In a word, the royal jelly nutritive composition is complete, easily is absorbed by the body, and regulates body metabolism, builds up health, and promotes longevity, and can promote and strengthen the vitality of epidermal cell, improves the metabolism of cell, prevents the effect of skin disease and skin maintenance.
7, protect liver: experiment showed, that royal jelly has liver protection functions such as the hepatocyte growth of promotion, ribonucleic acid suppresses cell liver protection functions such as " suicides ", and its function and HGF (HGF) are suitable.
8, promote hematopoiesis: oral or injection royal jelly, erythrocytic diameter is increased, and amount of hemoglobin and desmacyte number are increased, find that also the patient takes in the royal jelly 24 hours, iron content significantly increases in the blood.Studies have shown that this is owing to the result who stimulates Railway transportation to fail, and red blood cell and hemoglobin increase obviously all, the blood platelet a few days also increases.When experiment showed, to the oral royal jelly of mouse, can prolong the life span of mouse, the control group mice mean survival time is 6.5 days, and the royal jelly group mouse mean survival time then is 13.9 days.Latter's life span prolongs 1 times than the former.And royal jelly can also alleviate the inhibitory action of 6-MP to marrow, shows that royal jelly has protective effect to myeloid tissue, can excited hemopoietic function of bone marrow.
9, anticancer: a large amount of evidences, royal jelly have certain antitumaous effect.Zoopery proves, the inhibitory rate 75.83% of royal jelly, and the body weight gain of mouse is very fast in experimentation, begins a little less than the inhibition to tumour in several days, to inhibitory action enhancing in mid-term.By inference, may be to take royal jelly after a period of time, improve body's immunity, thereby suppressed the growth of tumour cell.It is reported the Jiangsu Inst. of Traditional Chinese Medicine researcher,, found that generally reflection takes back improvement person's 1279 examples, account for 93.7% with royal jelly freeze-dried powder (LRP) treatment 1365 routine malignant tumours; Appetite enhancer 1174 examples account for 86%, merge the side effect that the chemotherapy and radiation person can alleviate chemicotherapy, are that the patient can adhere to finishing the course of treatment.
In addition, royal jelly also has antimicrobial antiphlogistic, and the Radiological Defense heart is hypotensive, and the reducing blood lipid hypoglycemic promotes regeneration, improves effects such as sports achievement.
(5) hide cynomorium songaricum (HerbaCynmor ") is the parasitic Cynomoriaceae plant drying of perennial meat sliced meat stems. warm in nature, flavor is sweet.Return spleen, kidney, large intestine channel.Have tonify the kidney and support yang, benefiting essence-blood, ease constipation road just, clinical impotence, the soreness and weakness of waist and knees of being used for, the dry constipation of intestines, antifatigue, effects such as anti-anoxic.
Chemistry success: mainly contain triterpene substance: cynomorium songaricum terpene, ursolic acid, acetyl ursolic acid, volatile oil, palmitic acid, Sitosterolum, daucosterol, catechin, former catechin, amino acid, inorganic elements.
Pharmacological action: 1, strengthen immunity; Cynomorium songaricum alcohol extract 0.5g/kg mouse stomach can improve the ability of engulfing chicken red blood cell after 7 days; Can strengthen the empty class of mouse spleen haemolysis number in 2g/kgl0 days; Give deficiency of yang mouse gavaging 2g/kg7 days, can propose the conversion of product spleen lymphocyte and draw energy.The mouse gavaging water extract can increase the heavy and neutrophil leucocyte number of mice spleen in 10g/kgl9 days, increased the mice serum grain and counted hemolysin and hemagglutinin value, had the promotion humoral immune function.
2, anti-oxidant: experiment shows in the body, and Herba Cynomorii extract can stop ethanol to reduce the active and assorted high LPO of SOD.Experiment in vitro shows the effect that can directly remove hydroxy radical.In addition gavage mouse, anti-anoxic, antifatigue, high temperature resistance, stress ability such as cold-resistant are arranged with water decoction.
3, strengthen endocrine function: cynomorium songaricum alcohol extract 2g/kg give childhood rat oral gavage 15 days, can significantly increase the testosterone concentration in the male juvenile mouse blood plasma.Testosterone can promote cell growth, differentiation, maturation, strengthens muscle and quickens sick and wounded recovery, all exists in the masculinity and femininity body.It is reported: water decoction 10g/kg irritated stomach 9 days for male deficiency of yang mouse (intramuscular injection hydrocortisone), and the concentration of the serum glucocorticoid that can obviously raise makes it to return to normal level.The cynomorium songaricum water extract can make hypothalamus-hypophysis, and-adrenal cortex axle is suppressed the mice serum cortisol and obviously raises.
4, antifatigue: the cynomorium songaricum water decoction is given mouse stomach, and the mouse swimming time is prolonged, and the assorted high-amplitude of SCK reduces behind the load exercise, the general hyperplasia of motion back mitochondria, loose not damaged, explanation can realize its antifatigue effect on constitutional basis.Promote the animality maturation: test shows that Herba Cynomorii extract has the sexually matured effect of the animal of promotion, also can resist the mouse sexual behaviour that factor such as long-term anxiety causes and reduce.
5, anti-anoxic, experimental result shows, the cynomorium songaricum water decoction gavages can the significant prolongation time-to-live of mouse under anaerobic condition, has apparent normal pressure resisting oxygen lack, and cynomorium songaricum polysaccharide, total glucoside and total steroidal class all can prolong the anti-anoxic of mouse normal pressure, IS0 increases oxygen consumption and causes the anoxic time-to-live; Make the prolonged survival period of mouse mainline air.
6, improve brain function: feed cynomorium songaricum after 45 days, can improve the decline of dementia rat model memory, make by labyrinth time shortening 39.74%, prominent axle caudacoria dense matter thickness obviously increases.
7, remove free radical: methods such as employing ESR show the removing free radical effect experimental result of cynomorium songaricum, cynomorium songaricum can stop in vivo that serum that liquor damage causes and Intramitochondrial hepatocuprein are active to be reduced and lipid peroxide raises, and prove that cynomorium songaricum contains the removing free radical is had tangible action component.
8, relax bowel: experiment shows that cynomorium songaricum solution is the excited intestinal tube of energy under finite concentration, increases enterocinesia, has functions of loosening bowel relieving constipation.The mechanism that cynomorium songaricum relaxes bowel forms known saline cathartic such as Na2 with the water-soluble inorganic ion that contains in the intestinal mucosa, Mg S04, Na3 (P0) etc. are relevant.
9, anti-gastric-ulcer: the cynomorium songaricum decoction that experiment showed, hypodermic injection or oral DCS50% all has significant antiulcer action.The antiulcer action of DCS is relevant with PGE2 content increase in the stomach lining, and PGE2 can gastric acid inhibitory secretion and anti-gastric-ulcer effect.
10, antitumor: cynomorium songaricum all has inhibitory action to reverse transcriptase (RT) and people DAD polymerase a, has report to think that the oleic acid that cynomorium songaricum contains has the control function of tumor.
11, platelet aggregation-against: the rat platelet aggregation that cynomorium songaricum total reducing sugar, total glucoside, total steroidal class are induced adenosine diphosphate (ADP) all shows as inhibitory action.And be good dose-effect relationship.
(6) hide sealwort: (Huang jing), for my year living Liliaceae is planted the dry rhizome of taxi.The property do, flavor is sweet, return spleen, lung, kidney are strong.Effect with tonifying spleen yin-nourishing, invigorating the spleen moistening lung, kidney tonifying.Be used for empty weak, the mouthfeel food of weakness of the spleen and the stomach, body less, the dry larynx of the deficiency syndrome of the lung.Be longer than tonifying middle-Jiao and Qi, benefit support taste, sick body void, weakness of the spleen and the stomach, dry food less, asthenia of essence and blood.Compendium of Material Medica record: sealwort benefit controlled atmosphere essence, gentle, the muscle sufficiency of the five internal organs.Have not old for many years, the blackening of turning white, dedentition and give birth to effect.Modern pharmacological research, sealwort can effectively hypotensively can increase the symptom blood flow volume completely with blood sugar, plays and reduces blood fat and delay arteriosclerotic effect.
Chemical composition: mainly contain Siberian solomonseal rhizome polysaccharide class, steroid saponin, flavones, several amino acids, alkaloid, sweet mellow wine, lymphatic temperament, flower quinones etc.
Pharmacological action: 1, improve immunity: discover that sealwort has the effect that strengthens the human T cell.Can strengthen immune function of human body, promote the synthetic of DNA, RNA and protein.Lymphocyte transformation to the immunologic hypofunction patient has excitation.Compound can make mouse chest arteries and veins weight show to be increased, and can improve the humoral immunity level of thin chest sum of animal splenic T and external source thymus-dependent antigen, strengthens cellular immune function.Mouse is wrongly taken coarse solomon's seal polysaccharide 400mg/kg, and 7, can obviously strengthen thymus gland and spleen weight after day, obviously strengthen wind shape endothelium and do not unite the phagocytic activity of india ink.
2, anti-oxidant: sealwort can be caught high free radical ability.The sealwort decoction can obviously improve the content that superoxide dismutase activity in mouse red blood cell and the liver reduces cured brown matter in mouse cardiac muscle and the brain tissue.The sealwort oral liquid can significantly reduce the heart, liver lipid oxidation thing (LPO) generates, and increases superoxide dismutase, and the paddy Guang is peptide peroxidase (GSH-P) vigor and the super oxidation synthase of blood vigor.Show that sealwort can obviously improve body Green Tea Extract ability, to suppressing the effect that LPO generates the tool uniqueness.Coarse solomon's seal polysaccharide can reduce the carbon tetrachloride poisoning Mouse Liver: mda content in the tissue has anti-matter and refers to peroxidation.
3, anti-ageing: wrongly took decoction 27 days to mouse, can obviously reduce myocardium lipofuscin content and improve the liver SOD activity, the lipid peroxidation that the protection free radical causes has anti-aging effects to the infringement that biofilm structure and function cause.Wrongly take sealwort 6g/kg to mouse, the activity of 10 days red blood cell Na+ that can raise, K+-ATP enzyme.Siberian solomonseal rhizome polysaccharide promotes mouse lymphocyte conversion ratio, red blood cell, crystal nuclear, lens cortex superoxide dismutase SOD activity.Water decoction 2.59g/kgd, 3g/kgd can make skin hydroxyl dried meat amino acid content increase by 6.6% in 1 month for the mouse gastric lavage, significantly improved lactic acid dehydrogenase activity and brain homogenate catalase activity in cardiac muscle and the brain tissue, can obviously improve the mouse hypoxia-bearing capability.The telomerase activation of old and feeble rat brain, the gonadal tissue of can significantly raising.
4, antipathogen: experiment in vitro shows that the sealwort water decoction is to typhoid bacillus, and golden yellow or the like coccus, acid-fast bacilli and adenovirus and cancer virus have inhibitory action.Tuberculosis is had notable therapeutic effect, and curative effect is carried nearly isoniazid.In addition multiple fungi also there is inhibitory action.
5, improve adrenal cortex function: sealwort has the effect that suppresses adrenal cortex function, and caused fat, neat random the having some improvement of glycometabolism are advanced by adrenal cortex unit.
6, protection liver: coarse solomon's seal polysaccharide can obviously reduce the mda content in the CCl4 poisoning mice hepatic tissue, has lipoid peroxidization resistant.
7, antifatigue: the sealwort water decoction is wrongly taken mouse and is carried out the swimming test result and show, mouse prolongs at the frozen water swimming time, can strong mouse muscle power and to stressed condition down opposing can, have remarkable antifatigue effect, it is relevant that the many low thighs of this effect cause kinases (CK).Sealwort also has good anti-tubercle bacillus to do in addition, thereby is fabulous help anti-fatigue product.
8, anti-anoxic: experiment shows, the sealwort water decoction is wrongly taken and can be improved mouse and survive under anoxia condition and utilize ability, to increase often anti-sound when scarce.Significantly improve lactic acid dehydrogenase activity and brain homogenate catalase activity in cardiac muscle and the brain tissue, can obviously improve the mouse hypoxia-bearing capability.
9, radioresistance: Siberian solomonseal rhizome polysaccharide can obviously resist the minimizing of 6 ℃ of gamma ray induced mice peripheral leukocytes and total number of blood platelet, can obviously improve irradiation mouse peripheral red blood cells C3b receptor rosette rate and immune complex rosette rate.
10, coronary artery dilating, anti-scheming ischemic: experiment showed, that sealwort can make rat heart thigh convergent force obviously strengthen, the coronary disease mistake flow that exsomatizes is obviously increased.Intravenous injection have the antagonism pituitrin due to the effect of acute heart thigh ischemic.
11, anti-leucocyte reduces: Siberian solomonseal rhizome polysaccharide can the cruel amine of bright antagonism ring phosphorus institute reduce to locating the mouse PBL, the mouse spleen weight of immunocompromised is increased, its leukogenic effect may be the hyperplasia by the spleen interstitial cell, and performance compensatory marrow is made its function outward.
12, reducing blood lipid: exempt to take 100% decoction 10ml/d to hyperlipemia, 30 days, can obviously reduce trigalloyl oil-beta lipoprotein, cholesterol (TC), alleviate aorta wall patch and crown artery sclerosis.Exempt to take Siberian solomonseal rhizome polysaccharide 1.6ml/gkd to hyperlipemia, can obviously reduce serum LDL-C, LP (a), TC concentration and minimizing, the aortic tunica intima foam cells forms.
13, hypoglycemic: Siberian solomonseal rhizome polysaccharide 500/kg, can significantly reduce adrenaline, model mice blood sugar and liver CAMP content.Medicinal extract and methanolic extract can suppress the glycogen alcoholysis, and adrenal gland, chain urea toxin are brought out mouse that blood sugar raises, exempt from that the obvious functions of blood sugar effect is all arranged.
14, resistive connection nuclear: water decoction is external to have the obvious suppression effect to tubercle bacillus.
(7) hide the Radix Astragali (Mikvetch), be the root of the legume astragalus mongolicus or the Radix Astragali.Warm in nature, the flavor sweet.Go into spleen, lung channel.Have effects such as invigorating qi for strengthening superficies, nourishing blood and promoting granulation, diuresis, holder poison.
Chemical analysis: mainly contain Radix Astragali triterpene soap class, polysaccharide, saponin, flavones, 19 seed amino acids, compositions such as protein, trace element.
Pharmacological action in: 1, strengthen immunity: astragalus polyose can obviously increase mouse spleen, the thymus gland quality, to spleen due to the loose dragon is arranged by force, the thymus gland quality alleviates that tangible antagonism is arranged.Can make T cell number increase in mouse thymus and the spleen in addition, promote the generation of 1gG.Can strengthen the activation of human lymphocyte Turnover of Mouse Peritoneal Macrophages and neutrophil leucocyte.Complement after cobratoxin is handled is descended, and the cavy that phagocytic rate descends has the reparation of the complement of promotion, promote neutrophil cell raising and restore funcitons such as to engulf.Astragalus decoction can improve the regulating power of macrophage, T lymphocyte, bone-marrow-derived lymphocyte etc.And can obviously improve and specific immune function, humoral immunity, cellular immunity etc. is all had promote and humidification that EVAC is had tangible spread effect, have and self induce, promote to induce and active volatilization.
2, anti-oxidant: the generation of oxygen radical when astragalus flavonid 10mg/kS can reduce the rat heart muscle ischemic.Astragalus root total saponin 37.54g/ml adds the heart thigh that exsomatizes and preserves in the liquid, heart function and coronary flow are obviously strengthened. according to another report, flavones in the Radix Astragali has anti-radical action, and free radical is one of tumorigenesis disease factors such as mutagenesis, and the researcher falls the interior free yl level with flavones.Make its metabolism environment that destroys people's struma, reduce the accretion rate of tumour and suppress the swollen cell speed of growth.
3, delay senility: with A PS200mg/kg lumbar injection, mouse spleen is enlarged markedly, the increase of RND content reaches about 18%, can prolong cell survival, strengthens cellular metabolism, postpones aging.Astragalus polyose has direct removing MDA (LPO), improves the SOD activity, and the rabbit aortic smooth muscle cells (SMC) of in vitro culture is had good protective action because of the damage that free radical causes, effect such as aging and sclerosis of control arteries.With fibrocyte in the human embryo lung (HEL) dliploid of in vitro culture is the experiment die body, measure cell survival, the strong ability SOD content of training, test group can be grown for 77 generations as a result, and control group was only lived for 52 generations, the same generation ability of cell proliferation in age, SOD content and generation time-to-live all are higher than control group.Astragalus polyose can make in the old rats cell SOD contain obvious rising (150mg/kgP＜0.01) the anti-old and feeble effect of prolonging has been described.Astragalus polyose can obviously reduce the reason that contains of lipid peroxide in the rat plasma, and the deposition of lipofuscin is to cause aging organ balance to be decreased a kind of factor, and it and age are linear increase sexual intercourse.
4, prevent and treat angiocardiopathy: polysaccharide that extracts from Radix Astragali stem, leaf and saponin(e, through 17 of physiology, biochemical, morphology index consistent showing, to the heart of the acute myocardial infarction dog myocardial contraction that changes, dwindle; Myocardial infarction area, alleviate effect such as myocardial damage, and can further cause the rabbit ventricle to reduce heart throughput rate reducing, reduce MCO and protection ischemic myocardium.
5, improve sleep: astragalus saponin and water decoction irritate stomach or abdomen is annotated, and the mouse autonomic activities is reduced, and prolongs the lengths of one's sleep such as barbital, reduces fistfight.
6, increase bone density: decocting liquid 5g/kg gavaged the osteoporosis type rat to being caused by hydrocortisone in 60 days, can make the bone formation rate increase by 100%, the bone trabecula area increases by 37%, gavages in aqueous extract 5g/kgl2 week effectively to stop the bone loss of removal ovary rat.
7, antitumor: astragalus polyose is to the human lung adenocarcinoma of knurl, liver cancer, nude mouse in the mouse, the strain of human colon carcinoma dehydration oncocyte knurl all has the obvious suppression effect, suppressing ratio of outflow is 20%---51%, and to the mouse entity melanoma, effective tumour inhibiting rate of lung cancer is 20%--47%.According to another report, Radix Astragali water extract 100g/ml reaches 94.94%. to the inhibiting rate of human stomach cancer cell line AGS
8, skin makeup: the Radix Astragali can strengthen skin-nourishing and skin antibacterial ability, prevents skin aging, promotes hair growth, and is anti-loss.Contain the trace element of several amino acids and needed by human etc.Effect with skin nutrition promotes skin metabolism, improves skin resistance, makes skin delicacy, fitness.
9, control is dull-witted: it is reported, Japanology studies show that, the researcher raises the animal suffer from senile dementia with Astragalus Root P.E, found that and can significantly improve its cognitive ability, gives patients of senile dementia the oral obvious effects that obtained the capsule of heavy dose again subsequently.Studies show that this natural drug truly has smelting to treat the effect of degeneration cerebral diseased.
10, the influence of pair cell metabolism.The Radix Astragali can obviously delay human embryonic lung diploid fibroblast naturally-aged process, can prolong cell survival about 1/3; Healthy human lymphocyte silk division has inhibitory action in vitro culture in high concentration, and facilitation is then arranged during low concentration.
11, to the influence of nucleic acid metabolism.Astragalus polyose has the effect of antagonism mercurial, and the ribonic acid enzyme of body and inhibiting factor balance sysmte thereof are kept normally; To mouse peritoneal injection 200mg/kg the effect of remarkable inhibition liver, spleen alkalescence ribonucleic acid enzyme activity is arranged, but serum and acid core ribonuclease T. are not had obvious effect.
12, to the influence of protein.Astragalus decoction continuous irrigation stomach 10 days can significantly increase the speed that the 3H-leucine mixes serum, hepatic protein, and Protein content not had influence, thinks that the Radix Astragali can promote the renewal of mice serum and hepatic protein, and active ingredient may be polysaccharide; And astragalus saponin 1 also has similar effect.
13, anti-sudden change.Astragalus decoction raises significant inhibitory effect is arranged the lie prone bone marrow cell micronucleus permillage of the mouse active somatic cell that brings out and chromosome aberration percentage of aflatoxins, and along with increasing of dosage, more remarkable effect is situated between and also not exclusively suppresses the mutagenesis that aflatoxins is lain prone.The mechanism of action of the Radix Astragali anti-sudden change in living animal may be protected cell with its active ingredient, strengthens immunologic function and promotes DNA synthetic, and the wound repair effect of strengthening DNA is relevant.
14, beauty treatment.The main component of the Radix Astragali (be divided into polysaccharide, the liquor-saturated alcohol of-paddy steroid, trace element and choline, folic acid etc. though the merit of tonifying Qi is inferior to genseng, are sent out because of its this property of medicine is kind, walk table flesh, can be better with the Radix Astragali in beauty treatment side.Modern study shows that the Radix Astragali has enhancing and adds effects such as promoting organism metabolism.
15, to the influence of hematological system.Astragalus decoction causes the pressure drop of hemolytic deficiency of blood zooblast low to this hydrazine of acetyl, and the blood specific viscosity reduces, and the erythrocyte electrophoresis rate reduces, and electrophoresis time prolongation etc. all has the improvement effect.It is hematopoiesis function that the astragalus injection lumbar injection can strengthen the normal mouse grain, and making the single grain of marrow is that the CFU-GM number is apparently higher than control group; Caused by cyclophosphamide rat marrow hematopoiesis function there is obvious protective effect unusually, can stops the obvious minimizing of bone marrow nucleated cell number.Hairy Root of Astragalus membranaceus gavages, can improve red blood cell number, the reticulocyte counts of blood loss anemia mouse, increase red blood cell number, hemoglobin value, the packed cell volume value of hemolytic anemia mouse, can resist the decline of the leukocyte count and the bone marrow nucleated cell number of endoxan, X ray induced mice, the effect that promotes the hemopoietic system function is arranged.
16, protect kidney: the astragalus injection intravenous injection can make the seralbumin of rat MCN model obviously raise and can increase the blood fortune of glomerular capillary silk; To rabbit mesentery productive nephritis, can obviously reduce glomerular mesangium district IgG and C3 deposition.The Radix Astragali can significantly reduce the amount of albumen in the urine, alleviates the renal lesions degree.The mechanism of Radix Astragali treatment nephrotic syndrome is synthesized for promoting the protein of suffering from body, improves seralbumin concentration, thereby improves its clinical manifestation.
17, diuresis.The Radix Astragali has medium diuresis, human trial declines bright, this product can increase the urine amount and oxide is drained, give clinical dosage urine amount o.2g/kg and can increase by 64%, the diuresis duration of row's sodium amount increase 14.5%. Radix Astragali is longer, after giving rat skin lower injection, the generation that has no drug resistance after 7 days of sustainable 7 days of diuresis, successive administration.
18, antifatigue, astragalus polyose 250-500mg/kg lumbar injection, but the * deficiency of yang due to significant prolongation normal mouse and the hydrocortisone // mouse normal temperature swimming time, and increase mouse adrenal gland weight under the stress situation.
19, anti-anoxic.Astragalus oral liquid 20～50g/kg irritates stomach, astragalus polyose 280～500mg/kg lumbar injection all has remarkable antagonism to the mouse normal pressure of normal and isoprel processing and the cerebral anoxia due to decompression anoxic, cyanide poisoning anoxic and the ligation bilateral carotid, and can obviously prolong mouse has live time.
20, cold-resistant.The astragalus polyose lumbar injection can obviously strengthen low temperature resistant (5 ℃) ability that normal mouse, hungry mouse and oxidation cortisone are handled mouse, and its life span is obviously prolonged, but does not have obviously high temperature resistant (45 ℃) effect.
21, radioresistance.Astragalus polyose can impel the spleen tissue structure of the mouse damage behind the radiation exposure obviously to recover, and improves the super emblem structure of spleen endolymph cell, improves the activity of succinate dehydrogenase in the PBLC.And the mouse body weight due to right-60 ℃ of irradiations descends, leukocyte count falls now and the Ultrastructural change of liver all has obvious protective effect.
22, antiviral. astragalus decoction has direct inactivation of viruses effect, and can suppress the cytopathy behind the infective virus, can directly suppress varicella one herpes zoster virus, and the virus of duplicating is had the growth inhibitory action.Astragalus injection has certain blocking effect to the course of infection of epidemic hemorrhagic fever virus in the mouse suckling mouse body according to another report.The Radix Astragali has antivirus action or has the function that protection cardiac muscle cell rabbit is subjected to the virus infringement, and the experiment in vitro Radix Astragali comprises AIDS virus quite under the concentration inhibition virus function being arranged.
23, analgesia.Mouse writhing method and hot plate method experiment show that astragalus saponin 1 and sheep astragalin have obvious analgesic activity.
24, increasing intelligence. Radix Astragali decocting liquid drinks or irritates stomach to mouse, the effect of strengthening learning and memory of little mouse is arranged, and helps the storage of mouse brain to information.
25, antibiotic.To Shigella shigae, bacillus anthracis, a-Streptococcus hemolyticus, p-Streptococcus hemolyticus, corynebacterium diphtheriae, bacillus pseudodiphthericus, Diplococcus pneumopniae, staphylococcus aureus, Staphylococcus citreus, staphylococcus albus and hay bacillus etc. have antibacterial action to the Radix Astragali external.
26, anti-inflammatory.Astragalus saponin 1 irritates stomach or 5mg/kg intravenous injection for rat 50mg/kg all can be increased the rat capillary permeability that antihistamine and serotonin cause.25～100mg/kg irritates stomach, can significantly resist the rat paw edema that carrageenan causes, its inhibiting rate is linear in this dosage range.
27, hormone-like effect.Radix Astragali extractum, Radix Astragali lactone and Radix Astragali sterol are to rat. and weight such as the body weight of mouse, levator ani or kidney all do not have obvious influence, showing no anabolic hormone or the effect of male sex hormone sample. the Radix Astragali can make mouse obviously continue 10 estrus, and estrogenic promoting action is arranged.The bone that water extraction of astragalus membranaceus can suppress the removal ovary rat absorbs, and has function of resisting osteoporosis.
28, hemangiectasis: modern pharmacological research shows that Astragalus Root P.E has the effect of hemangiectasis coronary artery and whole body peripheral vessel.
(8), Colla cornus cervi extract: (Cervus elaphus Lin-naecie), deer horn glue are the jelly that ossified angle of animal in deer family and deer or Mei workerization deer or angle base are boiled into.Warm in nature, sweet, salty, the effects such as basin essence, warming kidney and enhancing yang of enriching blood of flavor.
Chemical composition: contain several amino acids.
Pharmacological action: 1, gonadotropic Effect: Colla cornus cervi extract is given rat oral gavage, can significantly shorten the latent excellent phase that the electric stimulus inducing adeagus erects, and mouse seminal fluid capsule great and mighty or powerful and prostate is had tangible effect of gain, and male mating ability is had humidification.
2, first blood: Colla cornus cervi extract is irritated stomach to anemia mice, can obviously increase content of hemoglobin, to red blood cell, leucocyte, blood not hematocrit in various degree raising effect is arranged.
3, antifatigue: Colla cornus cervi extract can significantly improve mouse and continue swimming time, and the obvious anti-fatigue effect is arranged.
(9), tribulus fruit extract (Puncturevine), this product is the fruit of zygophyllaceae plant puncture vine.The property flat, bitter, suffering, have that flat liver is separated strongly fragrant, promoting blood circulation by removing wind, antipruritic function makes eye bright.Dizzy, the distending pain in the chest and hypochondrium that is used to have a headache, breast close breast pain, hot eyes, and rubella is disturbed and itched etc.
Chemical composition: the sweet class of steroidal soap, flavonoids, alkaloid, peroxidase and volatilization wet goods composition.
Pharmacological action: 1, resist myocardial ischemia: the thick saponin(e preparation of puncture vine cauline leaf can strengthen cat and rabbit heart convergent force, and reducing heart rate expands strong coronary artery and peripheral vascular, has tangible function of resisting myocardial ischemia.
(10), Yohimbine (yohim bine), Yohimbine is the Apocynaceae devilpepper, a kind of natural plant composition-Yohimbine that extracts in the plants such as Rauvolfia yunnanensis.The treatment impotence is had unique effect, be to Yohimbine so far be that the most effective natural plant composition of impotence is treated in smelting.
Pharmacological action: the treatment impotence: Yohimbine is the alpha-2-adrenoceptor retarding agent, by blocking-up maincenter master-adrenocepter, makes the central sympathetic activation, and stimulates telotism.Yohimbine can also improve ball ketone level, excites sexual desires, and be telotism, it is reported to treating psychological erectile dysfunction more obvious.
According to external, Yohimbine (alpha-receptor blocking agent), telotism is to rely on cavernous body parteriole blood vessel, the main mechanism of action of Yohimbine is expansion penis parteriole blood vessel, increase the corpora cavernosa penis CBF, directly act on the cavernous body vascular smooth muscle, make telotism more lasting effectively, effect is approximate with U.S.'s " vigour ".With Yohimbine 43% erectile dysfunction there is significant curative effect according to external experiment is single.
(11), ginkgo biloba p.e (Ginkgo bilobalenf exatract) are Ginkgoaceae plant Ginkgo biloba leaf extract.The property flat, flavor is sweet, bitter, puckery.Functions such as having astringes the lung relievings asthma, dampness elimination, increase the blood vessels flow, improve microcirculation, hypotensive, reducing blood lipid, inhibition thrombosis, impel thrombolysis, and improve significantly memory disorders and well anti-ageing, antibiotic, enhancing sexual function.
Chemical composition: ginkgo mainly contains flavone compound, ginkgo lactones, polysaccharides from ginkgo biloba, terpene fat compound, bioactive ingredients such as various trace elements.
Pharmacological action: 1, enhancing sexual function, prevent and treat impotence: ginkgo biloba p.e contains flavone compound, can cause the guinea pig isolated heart coronary vasodilation, and can obviously expand the cerebrovascular of anesthetized cat, dog, increase the inhibitory action of cerebral blood flow (CBF), shrink the increase CBF thereby suppress parteriole.Other has the expansible corpora cavernosa penis smooth muscle of report Total Ginkgo Flavone-Glycoides parteriole, increases the penile blood flow amount, can obviously improve telotism kinetic energy, makes telotism, enhancing sexual function.Ginkgo can also be improved the blood circulation of body tissue's organ pipe in addition, comprising penis.It is reported that several all backs of administration 50% property kinetic energy impaired patients improves.Itself and Yohimbine, that nicotinic acid share effect is better.
2, reduce blood viscosity, accelerate VPV: ginkgo biloba extract can make the erythrocyte aggregation effect reduce, and VPV is accelerated, and the energy vasodilator, reduces blood viscosity.
3, strong smart effect: ginkgo biloba p.e has the effect of strong essence, because ginkgo has been rich in lysine, and lysine is the important component that forms sperm, also has the Spermatogenic action of tonifying the kidney and support yang.
4, anti-anoxic: ginkgo biloba p.e not only can change blood flowing characteristic, and can improve hypoxia-bearing capability.Energetic supersession was relevant when its mechanism of action may and be improved anoxic with the increase cerebral blood flow (CBF).
5, antianxiety: this product the treatment rat nervous with anxiety experiment in, present certain antianxiety activity, gingko lactones or ginkgo biloba p.e are the active ingredient of angst resistance effect.
6, delay senility: flavones base parent nucleus contains reproducibility hydroxyl functional group in the ginkgo leaf, can directly bring into play antioxidation, can remove free radical, regulate superoxide dismutase, the activity of antioxidases such as catalase, slow down the pathologic peroxidatic reaction of lipid, tangible anti peroxidation of lipid damaging action is arranged, therefore can delay senility.
7, improve memory: experimental result shows, ginkgo biloba p.e can obviously prolong the impaired mouse of memory and stop incubation period, heavy dose of alcohol extract can also shorten the incubation period of natrium nitrosum to the infringement model mice of memory, and its mechanism of action may be relevant with the cholinergic nerve that influences maincenter.According to another report, ginkgo leaf can increase second choline M2 acceptor, β one adrenaline, the density of acceptor and thyroxine releasing hormone receptor.Senile dementia patient and aged animal brain belong to acetylcholine M2 acceptor more then to be reduced.
8, protection brain tissue: ginkgo biloba p.e can increase cerebral blood flow (CBF), reduces resistance of blood flow, improves sleep, improves memory, and can prevent and treat and be afraid of golden gloomy disease, cerebral arteriovenous malformation and senile dementia etc.Ischemia apoplexy also there is therapeutic action preferably.Modern medicine study is found, connects the abnormal vascular disease that operation can't be handled, and ginko leaves flavone also can make its blood vessel dilatation.Western medicine the expert also think, the composition that ginkgo leaf extracted can shorten the degree that stroke patient convalescence alleviates apoplexy sequelae.Especially the people's ginkgo leaf to temporary disturbance of cerebral circulation has its unique effect, and the continuation disturbance of cerebral circulation is also had tangible curative effect.
9, remove free radical: studies show that ginkgo biloba p.e has the effect of removing free radical and superoxide anion.Human senescence is all relevant with a kind of harmful components free radical in the body with canceration.And antioxidants such as the flavonoids of ginkgo, terpene, vitamin C can effectively be removed free radical, also contain a kind of biocatalyst of more efficiently removing free radical in the ginkgo leaf.Ginkgo biloba p.e also has the effect of pre-anti-aging and variation in addition.
10, reducing blood lipid: the fat in ginkgo biloba p.e energy softening blood vessel, the removing blood, reduce serum cholesterol.Total Ginkgo Flavone-Glycoides has tangible reduction effect to serum triglyceride.Discover that further ginkgo leaf total flavonoid can obviously reduce apolipoprotein B and low-density lipoprotein.
11, prevent and treat hypertension: ginko leaves flavone can make blood vessel and blood normalization.Therefore, no matter be that the sort of type hypertension all has certain curative effect.Blood pressure is had dual regulation, and not only effective to hypertension, adjusting also has effect to low blood pressure.
12, anti-angiocardiopathy: flavonoids, bis-flavonoid all have hemangiectasis in the ginkgo leaf, improve microcirculatory effect.Flavonoids, ginkgolide have antagonism to platelet activating factor simultaneously, thereby suppress the formation of thrombus.According to clinical observation, ginkgo biloba p.e has very significant curative effect to coronary heart disease, angina pectoris, miocardial infarction, hypertension etc.
13, prevent and treat artery sclerosis: causing arteriosclerotic reason is that too much cholesterol is attached on the vascular wall in the blood, and in the course of time, blood vessel follows the string and becomes fragile.Ginko leaves flavone can directly be had an effect the vasoactive unusual part, removes the occluding vascular barrier, makes blood vessel natural extension, and blood circulation is smooth and easy, makes to face break blood vessel recovery softness and elasticity frequently.
14, anti-liver injury: ginko leaves flavone causes increasing of liver mda content to carbon tetrachloride significant inhibitory effect.The height of mda content reflects the power of membrane lipid peroxidating degree to a certain extent, therefore infer, ginko leaves flavone is eliminated oxygen radical and suppresses free radical formation effect membrane lipid peroxidation anti-with it closely related, and the prompting ginko leaves flavone has certain anti-liver injury effect.
15, anticancer: the active component in the ginkgo leaf can prevent or reverse the fibre modification of each tissue, and the undesired rising of Y one globulin and immunoglobulin (Ig) is used for leukaemia and solid tumor in the autoimmune disease such as reduction inflammation patient.Also can improve simultaneously the effect of anti-cancer chemotherapeutic agents, reduce bad reaction, make that the cancer cell of anti-cell toxicity medicament is more responsive effectively to chemotherapeutics.
(12), arginine (Arginine) natural arginine are that to be present in nucleoprotamine in a large number medium, also are the basic composition of range protein, so exist very extensive.
Arginine is white orthorhombic system (two water things) crystal or a white crystalline powder, and fusing point is 244 degree (decomposition), and 105 degree lose the crystallization water behind water crystallization, its aqueous solution is strong basicity, can be from air absorbing carbon dioxide water-soluble, be insoluble to ether, be slightly soluble in ethanol.
Arginine is the amino amino acid of a pair of, is composition in the ornithine circulation, is the condition essential amino acid, because arginine is described as obvious molecule carbon monoxide (NO) and precursor in life science, thereby more causes the concern of medical circle.Recent study finds that arginine has extremely important physiological function aspect health care.
Physiological function: 1, strengthen immunologic function: arginine can increase thymic weight, prevents involution of thymus (especially injured degeneration).Promote the maturation and the differentiation of thymic lymphocytes and the growth of CD cell and marrow and lymph CD cell.Arginine can also stimulate the cell of monokaryon in patient's peripheral vessels to antigen and fissional reaction, increases phagocyte, strengthens immunologic function.
2, prevent and treat impotence: arginine has the kidney tonifying, essence replenishing effect.Arginine is the precursor substance of neurotransmitters such as endogenous nitric oxide, the proof nitric oxide is a signaling molecule at present, the male sex is in the telotism process, at first be the sexual stimulus signal to be sent to the neural blood vessel system by chemical mediators such as nitric oxides by brain, make the interior smooth muscle of corpora cavernosa penis loose, make parteriole blood vessel dilatation, cavernous body blood flow and pressure sharply increase, the fibr tissue of adding penis shrinks, stop parteriole blood backflow in the cavernous body smooth muscle, from but penis is congested expands, make telotism strong.
According to another report, arginine is an oxidation precursor substance, can activate guanylate cyclase (GC), and the latter acts on atriphos and the cyclic guanosine monophosphate (CGMP) that produces.The generation cumulative effect of cyclic guanosine monophosphate can reduce the calcium ion level in the corpora cavernosa penis VSMC, thereby produces powerful vasorelaxation action, makes vascular smooth muscle loose, causes blood flow increase in the corpora cavernosa penis, and impels telotism.
According to another report, United States Medicine the expert discover, because oxidation ammonia energy hemangiectasis, therefore also can act on the blood vessel in the penis, make the strong impotence for the treatment of of telotism, use this effect, the medicine " vigour " of world-famous pharmacy corporation Pfizer research and development treatment impotence just contains the arginine composition, but because it has magical effect to the treatment impotence, and supply falls short of demand.
3, promote hormone secretion: arginine is the precursor substance that nitric oxide, creatine, phenylalanine, glutamate etc. have important physiological function, arginine and ornithine, phenylalanine and other neurochemistry element one work, and can synthesize and secrete the pituitary gland hormone.Arginine is that to keep the amino acid and the hormone of pituitary gland normal function in close relations, the secretion of hormone when arginine secreting hormone dominant mechanism makes it promote sleep.
4, protection blood vessel: blood vessel endothelium is all endovascular confluent monolayer cells, and it can produce nitric oxide, the important substance of a kind of diastole and protection blood vessel.One oxidation ammonia can be expanded in endovascular smooth muscle, makes vasodilation.In addition, nitric oxide also has other important defencive function, and the various various factors of its energy a word used in person's names stupid promotion artery congee for example, suppress ldl cholesterol oxidation, the jiggly free radical of platelet aggregation and deactivation.
5, protect the liver: studies show that arginine can increase the activity of arginase in the liver, help to change the ammonia in the blood into urea and excrete.So arginine is to hyperammonemia, diseases such as liver dysfunction have certain effect.According to another report, arginine in the energy and excess of ammonia that liver produces, therefore can help liver removal toxin in cirrhosis and fatty liver.The arginine famine is added cirrhosis, and hepatic coma can take place.
6, suppress tumour: additional arginine can reduce the volume of tumor-bearing animal, reduces the rate of transform of tumour, improves time-to-live and the survival rate of animal.In immune system, except that lymphocyte, cytophagous vigor is also relevant with arginine.After increasing arginine, can activate its system; Making it more can the kill tumor cell and target cell such as bacterium.
In sum, this product has effects such as the impotence of control, sex dysfunction, frigidity.
Six, manufacture craft:
1, allotment mixes: get and hide Cordyceps, Tibet sheep placenta, Tibetan wolfberry fruit extract, Qinghai royal jelly extract, Tibetan Herba Cynomorii extract, hide Rhizoma Polygonati extract, hide Astragalus Root P.E, hide raw material allotment mixing such as Colla cornus cervi extract, Yohimbine, ginkgo biloba extract, arginine, and stir.
2, capsule is filled: the raw material that stirs is sent into filling machine, raw material is inserted in the capsule.
3, capsule seals: the capsule with populated, seal by standard.
4, test package: will seal the capsule of mouth, and become formal product through being up to the standards, packing.
It is that the raw material in the component design is mixed by its physical characteristic that allotment mixes, the operation that stirs, and this operation gets raw mix.It is the raw mix that preceding operation is made that capsule is filled, and is filled in the operation in the capsule.It is the operation that the capsule with populated raw material seals that capsule seals, and this operation is not consume and the capsule opening for material composition in the capsule.Test package is a capsule of preceding operation being sealed mouth, and through being up to the standards, packing becomes the operation of formal product.
Seven, quality standard:
1, physical and chemical index:
Hide Cordyceps g/100g 8.33
Tibet sheep placenta g/100g 10.8
Hide wolfberry fruit extract g/100g 13.85
Qinghai royal jelly extract g/100g 5.54
Hide Herba Cynomorii extract g/100g 8.33
Hide Rhizoma Polygonati extract g/100g 10.8
Hide Astragalus Root P.E g/100g 8.33
Hide Colla cornus cervi extract g/100g 3.32
Tribulus fruit extract g/100g 10.8
Yohimbine g/100g 0.83
Ginkgo biloba extract g/100g 1.66
Arginine g/100g 27.7
2, instructions of taking: every day three times, each 0.6-0.9 gram, one after each meal.
3, be not suitable for the crowd: nephrotic, mental patient, diabetes, children and youth.
Eight, the specific embodiment:
Embodiment: get and hide 3 kilograms of Cordyceps, 4 kilograms of Tibet sheep placentas, hide 5 kilograms of wolfberry fruit extracts, hide 2 kilograms of seabee royal jelly extracts, hide 3 kilograms of Herba Cynomorii extracts, hide 4 kilograms of Rhizoma Polygonati extracts, hide 3 kilograms of Astragalus Root P.Es, hide raw materials such as 1.2 kilograms of Colla cornus cervi extracts, 4 kilograms of tribulus fruit extracts, 0.3 kilogram of Yohimbine, 0.6 kilogram of ginkgo biloba extract, 10 kilograms of arginine.
To hide raw materials such as Cordyceps, Tibet sheep placenta, Tibetan wolfberry fruit extract, Tibetan seabee royal jelly extract, Tibetan Herba Cynomorii extract, Tibetan Rhizoma Polygonati extract, Tibetan Astragalus Root P.E, Tibetan Colla cornus cervi extract, tribulus fruit extract, Yohimbine, ginkgo biloba extract, arginine and allocate mixing, and stir and send into filling machine, raw material is filled in the capsule, composition in glue leaks and the capsule opening, capsule is sealed, this operation gets the semi-finished product capsule, be up to the standards, packing becomes formal product.

Claims (2)

1, the Tibetan medicine Aili yuan-invigorating capsules manufacture craft is: allotment mixing, stirring, capsule raw material are filled, capsule seals, is up to the standards, and packing becomes formal product.
2, process conditions are: raw materials such as 3 kilograms of the Cordyceps in Tibetan, 4 kilograms of Tibet sheep placentas, 5 kilograms of the wolfberry fruit extracts in Tibetan, 2 kilograms of Tibetan seabee royal jelly extracts, 3 kilograms of the Herba Cynomorii extracts in Tibetan, 4 kilograms of the Rhizoma Polygonati extracts in Tibetan, 3 kilograms of the Astragalus Root P.Es in Tibetan, 1.2 kilograms of the Colla cornus cervi extracts in Tibetan, 4 kilograms of tribulus fruit extracts, 0.3 kilogram of Yohimbine, 0.6 kilogram of ginkgo biloba extract, 10 kilograms of arginine are allocated mixing, stir and send into filling machine, raw material is filled in the capsule, capsule seals, be up to the standards, packing becomes formal product.
CN2008101286392A 2008-06-17 2008-06-17 Tibetan medicine yuan-invigorating capsules Expired - Fee Related CN101322555B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101595986A (en) * 2009-05-01 2009-12-09 苟春虎 Male functional capsule
CN102641397A (en) * 2012-03-30 2012-08-22 常熟市海虞茶叶有限公司 Sheep placenta-containing composite capsule and preparation method thereof
CN104415066A (en) * 2013-09-09 2015-03-18 石家庄维奥化工有限公司 Composition for treating degenerative disease
CN110693885A (en) * 2018-07-09 2020-01-17 成都百裕制药股份有限公司 Pharmaceutical composition for preventing or treating sexual dysfunction and use thereof

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CN1136891C (en) * 2001-05-24 2004-02-04 林金平 Freeze dried compound queen bee powder
CN100348263C (en) * 2005-04-28 2007-11-14 陈宏棕 Chinese medicine preparation for treating male sterility
CN1970007A (en) * 2006-05-11 2007-05-30 苟春虎 Capsule for improving sexual function for men

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101595986A (en) * 2009-05-01 2009-12-09 苟春虎 Male functional capsule
CN101595986B (en) * 2009-05-01 2013-02-13 苟春虎 Male functional capsule
CN102641397A (en) * 2012-03-30 2012-08-22 常熟市海虞茶叶有限公司 Sheep placenta-containing composite capsule and preparation method thereof
CN102641397B (en) * 2012-03-30 2013-12-25 太仓市临江农场专业合作社 Sheep placenta-containing composite capsule and preparation method thereof
CN104415066A (en) * 2013-09-09 2015-03-18 石家庄维奥化工有限公司 Composition for treating degenerative disease
CN110693885A (en) * 2018-07-09 2020-01-17 成都百裕制药股份有限公司 Pharmaceutical composition for preventing or treating sexual dysfunction and use thereof

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