CN101284100B - Chinese caterpillar fungus compound capsules for prolonging and keeping the youth - Google Patents

Abstract

The invention belongs to the technology field of Tibetan medical health food, particularly a soft capsule prepared from Tibetan worm grass extract, Tibetan lamb placenta tissue hydrolysate, Tibetan saffron extract, Tibetan medlar extract, Tibetan royal jelly extract, Tibetan solomonseal extract, Tibetan milk vetch extract, Tibetan sea buckthorn extract, seaweed extract, coix seed extract, lycopene, etc. The preparation process for the soft capsule includes mixing the materials, stirring; filling into capsules, sealing; checking; and packaging to obtain finished product. The capsule is effective in improving immunity, caring skin, postponing aging, etc.

Description

Chinese caterpillar fungus compound prolongs the spring beauty nourishing capsule

One, technical field:

The invention belongs to the Tibetan medicine health food, relate in particular to hide Cordyceps extract, Tibet sheep placental extract, Stigma Croci extract, hide wolfberry fruit extract, hide peak royal jelly extract, hide Rhizoma Polygonati extract, to hide the health food that raw materials such as Radix Astragali extract, Tibet Fructus Hippophae extract, Sargassum extract, SEMEN COICIS extract, lycopene process.

Two, background technology:

This invention is to hide Cordyceps extract, Tibet sheep placental extract, Stigma Croci extract, hide wolfberry fruit extract, hide the Lac regis apis extract, hide Rhizoma Polygonati extract, to hide the health food that raw materials such as Radix Astragali extract, Tibet Fructus Hippophae extract, Sargassum extract, SEMEN COICIS extract, lycopene are made.This product has slow down aging, enhancing immunity, effects such as looks improving and the skin nourishing.In the market also not this series products occur, develop this product and can be and protect Construction Bank a kind of novel Tibetan medicine health food already is provided.This product is pure natural medicine food raw material, and the hard capsule preparation of making has no side effect, free from extraneous odour, taking convenience.

Three, summary of the invention:

Perpetual youth, healthy and beautiful, longevity are that everyone thirsts for the dream asked all over the world.Along with China's constant development of economy, improving constantly of national economy income and living standard, people are stronger to healthy, young and beautiful pursuit, particularly some achievers, researcher, crossed the personage that likes to be beautiful such as hebetic middle aged men and women.Loss along with the years, because each tissue organ function of health fails gradually, variation has taken place the organism endocrine balance and social development is accelerated, and live and work pressure strengthens, life such as be busy with one's work is irregular, many reasons such as stay up late, aging phenomenon mostly is in advance, some people particularly women 30 years old shortly past, bad senile symptom just appears, therefore take good care of one's health ahead of time, prevent and to delay each tissue old and feeble, make your perpetual youth, health, beauty, longevity.

Four, composition of raw materials: hide Cordyceps extract 3-5 kilogram, Tibet sheep placental extract 4-6 kilogram, Stigma Croci extract 1-3 kilogram, Tibetan wolfberry fruit extract 10-15 kilogram, Tibetan Lac regis apis extract 3-5 kilogram, Tibetan Rhizoma Polygonati extract 10-12 kilogram, Tibetan Radix Astragali extract 10-15 kilogram, Tibet Fructus Hippophae extract 12-15 kilogram, Sargassum extract 8-12 kilogram, SEMEN COICIS extract 15-20 kilogram, lycopene 0.8-1.0 kilogram.

Five, technical scheme:

(1) hide Cordyceps extract (Cordyceps): being to be grown in a kind of microorganism (fungus body) under the Qinghai-Tibet 3500-4500 rice special environment, is that China's Tibetan medicine is protected the medical material of Chinese medicine simply in the storehouse.In global Chinese, there is widely U.S.A transcribe, Cordyceps is always regarded as the panacea of treatment weakness by common people, be (Cordyceps, Cornu Cervi Pantotrichum, Radix Ginseng) first of the Chinese herbal medicine " three mend ", enjoy the good name of " the east legend are very precious " in the world and be described as disease-resistant anti-cancer to good Chinese crude drug, bring the world health by the expert.

Cordyceps is an Ergota Compositae fungus Cordyceps, colonizes in Stroma and larva cadaveric complex on the Hepialidae insect larvae.Warm in nature, sweet in the mouth are returned kidney, lung meridian.Have nourishing lung and kidney, mend smart marrow, Yin Yang balancing, hemostasis and phlegm, the function of delaying senility of giving birth to.To cancer-resisting, anemia weakness, hepatitis B, raising immune function of human body work the effect of consolidating.

Chemical constituent: Cordyceps contains saponins, cordycepic acid, Cordyceps polysaccharide, superoxide dismutase various active goods and materials such as (SOD), and aminoacid, vitamin and trace element, selenium, calcium, potassium, manganese, zinc etc.

Pharmacological action: 1, regulate immunologic function: (1) is to the potentiation of monokaryon one macrophage system function: Cordyceps water extract can obviously improve colloid carbon clearance degree in the mice blood, to the mouse monokaryon phagocyte, peritoneal macrophage, phagocytic functions such as reticuloendothelial system have tangible activation.It is bright to engulf test card in the body, and this product can significantly improve the phagocytic function of Turnover of Mouse Peritoneal Macrophages.

(2) to the influence of body immunity: Cordyceps and Cordyceps polysaccharide can make mice serum 1gE content obviously increase, and have improved the serum hemolysin level, induce splenocyte to express the IL-2 receptor.

(3) increase natural killer cell (NK) activity: studies show that the administration of Cordyceps alcohol extraction liquid can obviously strengthen the killing activity of the inside and outside NK pair cell of mice body.

2, kidney invigorating and YANG supporting: Cordyceps scalable renal function, nourishing YIN is YANG invigorating again, and is not empty not high, vital base and primordial QI consolidating, tonification kidney tonifying.But Cordyceps also has androgen effect spermatogenesis, and to impotence and seminal emission, the disease of the insufficiency of kidney-YANG of soreness of waist and knee joint is effective in cure.

3, adjusting sexual function: Cordyceps has certain androgen-like action, can make the weightening finish of castration male rat childhood seminal vesicle.Male mouse blood plasma cortisol content is increased for mouse stomach, adrenal gland's cholesterol is increased, adrenal gland's weightening finish has preventive and therapeutic effect to " deficiency of yang type " due to the oxidation cortisone, and sexual disorder is had the adjusting restitution.In addition, Cordyceps also has the synthetic and secretion of promotion and adrenal cortex reinforcing hormone.

4, defying age: Cordyceps can alleviate the infringement to the body biochemical process that descends and cause thus owing to the old and feeble maincenter catecholamine levels that causes, and removes human body harmful's free radical, thereby plays slow down aging, the effect of good health and a long life.The defying age result of the test shows, the Cordyceps polysaccharide of separate sources all has in various degree prolongation effect to life span of drosophila melanogaster, thereby the proof Cordyceps polysaccharide has function in delaying senility.

5, antioxidation: Cordyceps can suppress lipid peroxidation and generate; Strengthen erythrocyte superoxide dismutase vigor.Cordyceps can suppress MDA in rat, the mouse brain.According to another report, TaiWan, China ancient Chinese name for Venus hospital carries out human trial to the nephrotic, finds to take Cordyceps after 1 month, and tangible antioxidation reaction is arranged in the blood.

6, looks improving and the skin nourishing: in present medical circle, in the confessed seven big class anti-aging beauty-care active component, Cordyceps just contains five big classes, is respectively polysaccharide, aminoacid, polypeptide (protein), nucleic acid and vitamin (other two big flavonoid and soap class).Cordyceps also has endocrine regulation, and tangible calmness and syngignoscism are arranged, and has the looks improving and the skin nourishing effect.

7, treatment cardiovascular diseases, strengthen cardio and vascular function: Cordyceps has the adjusting cardio and vascular function, and blood pressure lowering is arranged, blood fat reducing and reduction myocardial oxygen consumption improve cardiac muscle and cerebral anoxia, arrhythmia, resisting fatigue and the anti-ageing effect of waiting for a long time make the running of cardiovascular and cerebrovascular vessel normal health.

8, antitumor: Cordyceps has the synthetic function of human activin DNA, can strengthen autoimmunity, and leukocyte is engulfed the oncocyte encirclement of the bad degeneration of human body and produced normal cell, oncocyte is reduced or disappearance, and tumor also can slowly be contracted to disappearance.The Cordyceps water decoction has certain inhibitory action to mice S180.Antitumous effect to Ismipur has potentiation, and the growth of mouse subcutaneous transplanting lung tumor is had the obvious suppression effect.According to another report, Cordyceps mouse entity S180 tumor etc. is had inhibitory action, intravenous effect is 100%.The average inhibitory rate 45.71% of report is also arranged.

Cordyceps polysaccharide: have anticancer and immunosuppressive action: with lotus tumor BALB/C is that model is observed Cordyceps polysaccharide and can obviously be suppressed tumor growth. studies show that, Cordyceps polysaccharide can activate phagocytic function and DTH reaction, directly or indirectly discharge the cytotoxic factor killing tumor cell, suppress tumor growth, prove that Cordyceps polysaccharide has obvious antineoplastic.

9, protect the liver: Cordyceps has improves the effect that chronic type b, hepatitis C symptom have the virus removed.Surface antigen is turned out cloudy; make liver function recovery normal; reach the effect for the treatment of both the principal and secondary aspects of a disease; according to another report; cordyceps sinensis polysaccharide liposome (CPL) can significantly reduce the activity of ALT and AST in the hepatic injury mice serum; murine liver tissue, pathological section show, the CPL of senior middle school's agent has protective effect to the CPL that the mouse liver injury due to amino half sugar of D-and middle agent are to the hepatic injury due to four carbonoxides.The prompting Cordyceps has function for protecting liver and reducing enzyme activity.Cordyceps has certain preventive and therapeutic effect to hepatitis B in addition.

10, strengthen the cardiac pulse ability, Cordyceps mycelium extract 100ug/ml can obviously strengthen the active contraction intensity of rat in the atrium, prolongs contraction time.

11, resisting fatigue, high temperature resistant, anoxia enduring: with Cordyceps mycelium extract 100-200mg/kg mouse swimming test, the result proves that swimming time prolongs, and has the resistivity under physical strength reinforcing and the stressed condition.Cordyceps group mouse stomach has the high temperature resistant effect of obvious anti-fatigue.The lumbar injection Cordyceps has the increase resisting oxygen lack.

It is reported that the double-blind trial of Medical School of Peking University confirms, Cordyceps far surpasses Radix Ginseng in the lifting of physical ability and explosive force, the Chinese female player who in 1993 and Olympic Games Women's 1000m in 1994 race, wins the title, to make finish the full distance in 42 seconds of whole world motion circle shock with breaking a record. its reason is that the athlete takes Cordyceps extract for a long time, to promote explosive force, so the health preserving effect of Cordyceps is subjected to attracting attention of west biochemical medicine circle.

12, blood pressure lowering, blood fat reducing: the factor that causes cardiovascular disease is a lot, but mainly is that blood fat increases and causes atherosclerotic to cause, therefore controlling hyperlipemia disease just becomes the key of preventing and treating cardiovascular disease.Cordyceps confirms through the clinical observation of strictness, and serum total cholesterol (CT) concentration, serum triglycerides (TG) concentration are significantly descended, and has tangible blood pressure lowering, the effect of blood fat reducing.

13, blood sugar lowering: the CHWC polysaccharide in the Cordyceps thalline, lumbar injection 50mg/kg has significant hypoglycemic activity, onset in 3 hours.To the alloxan diabetes model mice, the obvious functions of blood sugar effect is arranged, descend about 40% than matched group.

14, antiasthmatic-antitussive has better curative effect to emphysema, tracheitis: be the common respiratory tract infection of respiratory system disease spring, pulmonary infection, disease such as chronic cough, asthma, because its clinical shape is to influenza and for similar, a lot of people do not attract great attention, thus delay treatment.Lung heat clearing good medicine Cordyceps is discharged by the guiding pus, removes outmoded expectorant piece, nourishes lung tissue, the activate immunity function is removed respiratory disorder, will effect a permanent cure, consolidates, nourish and combine, fundamentally improve lung functions, recover the mucosa activity, improve immunologic function.

The also expansible bronchial smooth muscle of Cordyceps strengthens epinephrine, and to the lung qi loss, the disease that the lung power consumption is hindered dyspnea due to deficiency, phthisical cough expectorant blood has a significant effect.It is relevant with deficiency of both the lung and kidney that the traditional Chinese medical science thinks that old-slow-bronchial tube is sent out the people repeatedly.Cordyceps is warm in nature, vital essence replenishing and marrow benifiting, and nourishing lung and kidney, this thing is protected lung qi." from Bencao Congxin " record, Cordyceps protects the lung kidney tonifying, and hemostasis and phlegm ends the phthisical cough effect.Its nature and flavor, sweet, warm, go into lung, kidney channel.But it is bright to go into the lung tonifying the lung, and following kidney is tonify deficiency the moon then, has lung benefiting and protects lung, relieving cough and resolving phlegm, hemostasis tonifying deficiency, effects such as strong vital essence.Be usually used in treating chronic cough dyspnea due to deficiency, phthisical cough spitting of blood, impotence, seminal emission, soreness of waist and knee joint etc.The chronic cough dyspnea due to deficiency that the treatment old-slow-bronchial tube causes.

15, tonify deficiency, the postoperative rehabilitation effect, the effect that Cordyceps has anticancer, antiviral special efficacy, Cordyceps polysaccharide have strengthening the body resistance, improve immunologic function contains abundant vitamin and selenium element in the Cordyceps; Can both the enhancing human body immunity system, build up resistance.Patient has consumed a large amount of nutrient substance during sick, take the nutritional labeling that Cordyceps just in time can be replenished the various urgent needs of body this moment, recovers patient's muscle power, and is very favourable to physical rehabilitation.Postoperative patient has a delicate constitution, and resists the virus attack ability and obviously reduces, and wound healing also is badly in need of nutrition goods and materials such as a large amount of protein and vitamin.Protein content is repaired damaged tissues in the Cordyceps up to 27.81% pair, and recovering body constitution has tangible effect.

16, memory reinforcing: contained nucleotides bioactive ingredients in the Cordyceps, edible back is found, the increase of hemoglobin and oxygen affinity helps supplying with cerebral tissue, the cell oxygen carrying content increases, thereby eliminate the tired and raising ability of learning and memory that brain is not enough because of oxygen supply and shortage nutrition causes.According to another report, Japanology finds that nucleotide pair ischemic neurocyte has protective effect.The mouse brain cell mortality that found that diet nucleotide is fewer.Experiment showed, edible nucleotide pair ischemic, neurocyte has protective effect, takes nucleotide and shows in zoopery and can prevention of brain block.

(2) Tibet sheep placental extract (sheep ' s), (Placenta caprae seu ovis extract).Be conceived 3-5 month sheep embryo of tibetan sheep, utilize biotechnology to extract biological activity.China's tradition Chinese medicine is to animal Placenta Hominis application history for a long time.According to the record of herbal ridge order, warm in nature, the sweet-salty of sheep placental extract.Effect with the kidney invigorating, replenishing essence, benefiting qi and nourishing blood.The clinical men and women's of being used for asthenia, neurasthenia, QI and blood deficiency, spiritlessness and weakness, prolonged illness loss, spontaneous sweating, sexual disorder and endocrine disturbance are caused a disease all effective in cure.Modern medicine study, sheep placental extract is a kind of polypeptide protein material or perhaps the living cells thing that extracts from conceived Placenta caprae seu ovis, but this material activating human body skin and trachea function, effectively promote body metabolism, enhancing human body immunity power, promote human tissue cell's division, cell activity enhancing, reinforcement Skin Cell regeneration capacity, speckle dispelling, wrinkle-chasing, enhancing skin elasticity and gloss, delay youth, skin whitening, defying age, relieving mental strain and helping sleep, improve memory, allaying tiredness etc.

Chemical analysis: contain DNA (deoxyribonucleic acid) and nucleic acid, polypeptide protein, ten several amino acids, mucopolysaccharide, lecithin, vitamin B group etc.

Pharmacological action: 1, antioxidation: sheep placental extract was to 20 months healthy geriatric rat 150mg/kg every day body weight, 300mg/kg, 600mg/kg per os award sheep placental extract solution, after 80 days, measure respectively and respectively organize superoxide dismutase (SOD), malonaldehyde (MDA), monoamine oxidase, MAO (MAO) in rat erythrocyte and the tissue.The sheep placental extract SOD content in the old rats erythrocyte that can obviously raise reduces MAD content in serum and the hepatic tissue, and reduces cerebral tissue MAO vigor, so sheep placental extract has antioxidation to old rats as a result.

It is reported that the foreign study experiment shows that (1) fruit bat average life increases by 17.7%, human body is taken 15 days experimenter's lipid peroxides and is descended, and superoxide dismutase (SOD) value rises, and illustrating has positive effect to human body MDA (malonaldehyde), SOD.(2) rat blood serum and liver MDA descend 15%, and lipid oxide is had inhibitory action.(3) rat blood serum SOD raises 9.63%, and the manganese antioxidase raises 33.13%.

2, defying age: sheep placental extract has irritation cell regeneration capacity, slow down aging.It is reported that embryonic stem cell that sheep placental extract and umbilical cord contain and adult stem cell, these active component have face nourishing antidebilitation and act on always.

3, enhancing immunity; Studies show that, sheep placental extract compares mice nonspecific immunity and specific immune function index analysis, the phagocytic function of the thymus of sheep placental extract high dose group, low dose group, index and spleen index and mononuclear phagocyte all obviously improves, the conversion reaction of splenocyte strengthens, serum hemolysin generation value also increases, so think that sheep placental extract has the effect that improves the mice body's immunity.

4, endocrine regulation: sheep placental extract has obvious effects to regulating the hormone secretion function, can improve human body hormone secretion level, the aging of delaying female ovary, changes the ovary function, prevents climacteric obstacle, physiological change.

5, looks improving and the skin nourishing: studies show that, contain a series of micromolecule polypeptides such as peculiar superpower biological activity SF and BF in the sheep placental extract, its relative molecular weight is 3800-5000, it can activate Skin Cell regeneration, make it to breed degree of progress speed, activation skin surface tissue, removing also stops harmful oxide to be accumulated and melanocyte formation melanosome, mottle can't be formed, keep skin-whitening, promote the elastin laminin cell proliferation, make the skin reticular fiber structure become closely flexible, keep moisture of skin to be difficult for running off and replenish skin-nourishing comprehensively, the balance skin metabolism is eliminated pachylosis, dry and cracked phenomenon makes skin become tender and lovely.Therefore sheep placental extract has just enjoyed the women to welcome since coming out.

6, smooth away wrinkles: sheep placental extract can promote the elastin laminin cell proliferation, makes the skin reticular fiber structure become closely flexible, makes moisture be difficult for running off, and replenishes skin-nourishing comprehensively.According to another report, the loose corrugated reason of the skin influence that is free radical.Sheep placental extract has the effect of oxidation and removing free radicals, can dispel facial wrinkles.

7, promote hemopoietic, improve anemia: research thinks, sheep placental extract can hemopoietic tissue, promotion hemopoietic has tangible anti-anemia effect, the effect of rising erythrocyte significantly promotes the bone marrow hematogenesis function, improves the asthenia universalis symptom.

In addition, sheep placental extract also has the absorption that improves sleep, promotion human body metabolism, adjusting sympathetic nerve, strengthens protein and other nutritional labeling.

(3) Stigma Croci extract (Stigma croci) (Stigma Croci, Stigma Croci), the perennial perennial root herbaceous plant of Iridaceae safranine Pittosporum, croceous dried floral stigma.Sweet, the mildly bitter flavor of property.The traditional Chinese medical science think have blood circulation promoting and blood stasis dispelling, blood-cleaning detoxifying, the resolving stagnation for tranquilization effect.Have analgesia, diaphoresis stimulate the menstrual flow, dispel the wind cold, be good for the stomach, alleviate effects such as climacteric.Stigma Croci is a rare Chinese medicine simply, has unique effect aspect nourishing blood and promoting blood circulation.According to Compendium of Material Medica record, Stigma Croci can " invigorate blood circulation, main motive melancholy, smelting palpitation with fear again." use Stigma Croci clinically and dredge effects such as channels and activating collaterals, the blood stasis dispelling of stimulating the menstrual flow, dissipating blood stasis relieving accumulation of pathogens, reducing swelling and alleviating pain, removing pathogenic heat from blood and toxic substance from the body, troubled thoughts pent-up.Be widely used in diseases such as anemia body void, menoxenia, postnatal blood stasis, general aching, traumatic injury, neurasthenia, palpitation with fear is demented by China and foreign countries' medical circle.Other has report, and Stigma Croci is very famous and precious simply Chinese crude drug, has and nourishes blood, invigorate blood circulation, and removing heat from blood, effects such as regulating menstruation by adjusting the flow of blood, be undivided with blood woman's all one's life, and energy and blood of human body is full, and the ability hair is deceived profit, skin is glossy.

Chemical constituent: main component carotenoid is main pigment of Stigma Croci and active ingredient.Comprise the Stigma Croci aglycon, saffron glucoside and Stigma Croci mono-methyl, Stigma Croci dimethyl ester etc.It after the Picrocrocin hydrolysis volatile safranal.Volatile oil, diphenyl ethanol etc.

Pharmacological action: 1, antioxidation: the Stigma Croci extract has removing and inhibitory action to oxygen-derived free radicals.

2, health invigorating: under long-term work and pressure, modern female body constitution relatively a little less than, very easily be subjected to virus evil to cause various diseases and gynecological inflammation.And Stigma Croci can strengthen the immunologic function of cell, promotes the huge function of biting, and around the scavenger cell " rubbish ", thereby plays self-resistance, away from the effect of viral disease invasion.

3, regulation of mental activities pneumostatic: work long hours and life stress, make the woman feel the mood unhappiness, discharge nowhere, particularly there is the anxiety sense in climacteric women regular meeting, feels to upset, and symptoms such as tired, hypopnea are arranged, so that temper becomes quick-fried dry.Stigma Croci energy endocrine regulation is removed the mottle that causes because of the endocrine disturbance, and can in time promote the blood of human body circulation, the supply of blood oxygen, thus make women's QI and blood smooth and easy, keep good physical and mental statuse.

4, the skin Caring that nourishes blood: modern female gathers quickening because of work and life joint, causes symptoms such as anxious, sleep quality reduction easily, be reflected in the face skin anoxia, lose natural gloss, can occur when serious that the blood stasis of blood stagnates, pigmentation, chloasma, mottle etc. occur.Stigma Croci can be brought into play its anti-skin anoxia function of invigorating blood circulation to greatest extent, and obviously blood circulation promoting allows skin obtain competent blood oxygen, moisture and nutrition, makes skin dynamic, and fine and smooth moist, confidence gradually recovers one's health.

5, blood fat reducing: the Stigma Croci total glycosides can obviously suppress the rising of Carnis Coturnicis japonicae by serum TC, TG, LDL-C, VLDL-C and AI due to the hyperlipidemia diet, can alleviate tremulous pulse due to the hyperlipidemia feedstuff, the formation of atherosclerotic plaque, but Stigma Croci aglycon cholesterol reducing promote lipid metabolism.

6, suppress tumor: Stigma Croci 100-200mg/kg mouse gavaging is to S ₁₈₀, ehrlich carcinoma, MCA sarcoma all have the inhibition effect, its effective ingredient is Stigma Croci aglycon (crocetin)

Also have in addition, promoting blood circulation and hemostasis, removing pathogenic heat from blood and toxic substance from the body, promote the arteria retina blood flow, functions such as resisting fatigue, relieving constipation.

(4) hide Fructus Lycii (Lycium barbarnm extraat), Fructus Lycii is the sub-mature fruit of matrimony vine of solanaceae plant.The property flat, sweet in the mouth.Have by Liver and kidney, promoting generation of vital essence and blood makes eye bright, lung moistening, beauty treatment, functions such as fat-reducing.

Chemical constituent: the Fructus Lycii main component has polysaccharide, aminoacid, Folium hydrangeae strigosae alkali, carotene, vitamin B1, vitamin B2, various trace elements such as multivitamin such as vitamin C, nicotinic acid and manganese, chromium, zinc, copper, magnesium, calcium, germanium, cobalt, ferrum.

Pharmacological action: 1, protection birth-death system, it is reported that achievement in research of HSPH of Wuhan University shows, lycium barbarum polysaccharide can produce protective effect to the reproductive system that is damaged by effect " hypothalamic-pituitary-gonadal " this axis.

Experiment shows that lycium barbarum polysaccharide promotes hypophysis secreted glandular hormone by the gonadotropin effect, and " hypothalamic-pituitary-gonadal " this axis is produced the multilamellar regulating action, impels the spermatogenesis process unimpeded normal with testis sexual cell growth.

2, sexual function improving: Fructus Lycii has invigorating the liver and kidney, promoting generation of vital essence and blood, supporing yang function.No matter be that insufficiency of kidney-YANG, deficiency of the kidney yin all have certain effect, Fructus Lycii extract also has the effect of short gonad function, and plasma testosterone level is significantly raise, and property kinetic energy is gone down, and sexual impotence plays an important role.

3, enhancing immunity: Fructus Lycii is a medicine-food two-purpose food, and the Fructus Lycii polysaccharide has enhancing immunity, and antitumor action can strengthen the cell anti-cancer function selectively.Lycium barbarum polysaccharide can strengthen natural killer cell and lymphocyte vigor, promotes interleukin to generate, and strengthens monocytic immune vigor.The Fructus Lycii polysaccharide also has antimutagenic effect, when mutation produces genetic damage and cell mutation, can repair damaged cell and recover its normal function.

4, defying age: Fructus Lycii has the rejuvenation effect, and showing as to stimulate gonad and endocrine, strengthens hormonal secretion, strengthens the physiological function of brain function and neurocyte.The toxin phenomenon occurs accumulating in the blood though can avoid people's age growth, thereby keep the normal function of in-vivo tissue.But Fructus Lycii polysaccharide antagonism free radical peroxidase activity strengthens superoxide dismutase and glutathione peroxidase vigor, thereby the damage that alleviates the radical pair body has the effect of defying age.

5, the clay thing of a kind of indomitable vitality of Fructus Lycii, the traditional Chinese medical science think that taking Fructus Lycii can help human body to strengthen energy, nourishing the liver and kidney, replenishing vital essence to improve eyesight, the increase immunity that nourishes blood, and the effect that Fructus Lycii adapts to most is exactly a resisting fatigue.Resisting fatigue: Fructus Lycii can be improved hydroxyproline concentration, thereby improves muscular strength, and fatigue capability is strengthened.

Six, the liver protecting: Fructus Lycii extract has certain effect to hepatoprotective and fatty liver.Reason is that Fructus Lycii contains a kind of effective ingredient one Folium hydrangeae strigosae alkali, and it is effective to the treatment liver.Pharmacological research shows that Folium hydrangeae strigosae alkali has the fat of inhibition to deposit, and promotes the effect of liver cell regeneration in hepatocyte.Concerning the liver patient, the Folium hydrangeae strigosae alkali in the Fructus Lycii can prevent that fattiness stores in the liver, and lipotropic effect is arranged, and contained chlorophyll helps the liver detoxification effect in the Fructus Lycii, can also increase and improve liver function simultaneously.Chronic hepatitis patients, especially fatty liver patient.

7, blood fat reducing: Fructus Lycii extract can reduce the rat cholesterol, and the cholesterol that can obviously suppress hypercholesterolemia and the caused rabbit anteserum of Adeps Sus domestica feedstuff increases.

8, blood sugar lowering: wolfberry fruit extract can reduce rat blood sugar significantly enduringly, improves carbohydrate tolerance.

9, control age-related macular degeneration: Fructus Lycii has the soothing liver-QI effect that makes eye bright.To chronic hepatitis, central serous chorioretinopathy, optic atrophys etc. are evident in efficacy.Ageing disorders such as old organ senescence had very strong improvement effect.Discover that Fructus Lycii helps to reduce the generation of old degeneration maculopathy.

10, anti-apoptotic: apoptosis is called programmed cell death again.Interrelated data shows that brain normally has 10 nerve cell deaths every day approximately, and the human body neural thin breast of tissue regeneration promoting more not.When the fast a large amount of apoptosis of thin breast, senilism, weak, film attenuation and atrophy can appear in the people, skin kraurosis, and with a haggard face, memory and ability of thinking descend, even it is slow-witted old disease to occur.

Apoptosis except with occur outside the Pass pathology and inherited genetic factors have, a large amount of apoptosis fast and two factors are closely-related; First free radical is made the oxidation reaction of use free radical with old and feeble closely related, causes that the free radical of cellular oxidation all can cause apoptosis.Studies confirm that, the cerebroside ester that Fructus Lycii contains is that oligosaccharide combines formed glycosides with the ceramide terminal hydroxyl, owing to cerebroside ester is combined into by hydrophilic glycosyl and lipophilic ceramide, be one of important component of cell membrane, can keep cyto-architectural integrity.Simultaneously, cerebroside ester can form hydrogen bond network widely in biomembrane polarity and nonpolar interface.This is to constitute the constitutionally stable key factor of biomembrane stratiform.

According to another report, Ca2+ extensively raises in the inductive thymocyte cell of LBP DEX capable of blocking, suppresses the inductive dna segmentization of DEX, and inhibitory action has dose dependent, its mechanism of action may pass through to reduce the wide concentration of cell C for LBP, suppresses the endonuclease enzyme activation, thus the blocking-up apoptosis.

11, antitumor: the lycium barbarum polysaccharide combination with radiotherapeutic has certain radiosensitizing effect to acute weary oxygen tumor cell.Lycium barbarum polysaccharide has in non-specific antitumor and the specificity antineoplastic process macrophage certain activation is all arranged.With S180 lotus tumor Bal6/C mice is model, discover, mice with tumor spleens cell number and activating T cell multiplication capacity can be recovered and improve to lycium barbarum polysaccharide, promotes the active and TNF secretion level of NK, and the prompting lycium barbarum polysaccharide can strengthen cellular immune function makes it suppress the dominant mechanism of tumor effect.

12, beauty treatment is preserved youthful looks: deposit in hepatocyte so defying age can suppress lipid, promote hepatocyte new life's effect.Fructus Lycii contains carotin, and compositions such as thiamine, riboflavin, Yan acid have moist skin, and the color of preserving youthful looks is the good merchantable brand of beauty treatment.Fructus Lycii can improve the ability to take oxygen of skin, can play the effect of skin whitening.

It is reported that Britain, French medical science man discover that Fructus Lycii contains a kind of vitamin of not meeting, and is named as " vitamin ", is also referred to as the vitamin of preserving youthful looks.So Fructus Lycii extract has extremely strong skin maintenance effect.

(5) hide Lac regis apis extract (LacRehis Apic), this product is excretory milky jelly of worker bee glandulae pharyngeae and the formulated liquid of Mel of Apidae insecticide Apis etc.The property flat, sweet in the mouth, acid.

Chemical analysis: the fatty acids of Lac regis apis, sterols, protein, 18 seed amino acids, vitamin A, vitamin C, vitamin E, vitamin B group, folic acid, pantothenic acid, inositol, nicotinic acid, adenylic acid and adenosine, uridnine, guanosine; Acid p'tase and alkaline phosphatase, enzymes such as acetylcholine esterase.

Pharmacological action: 1, raise immunity: discover that edible Lac regis apis has three big functions to immune system: the one, balancing human body, endocrine regulation, thus stablize immune system.The 2nd, there is nature to remove function, can remove harmful substance in the human body, the protection immune system.Three provide comprehensive special nutrient, nutrition immune system.Therefore edible Lac regis apis can stimulate body to produce a large amount of antibody, significantly strengthens cellular immune function and humoral immune function, and bone marrow and lymphoid tissue and whole immune system are produced useful influence.The enhancing human body immunity function.

2, slow down aging: studies show that, Lac regis apis is by generally acknowledged " life longevity factor ", and it contains a large amount of protein of needed by human, and the serum albumin that particularly plays an important role accounts for 2/3, globulin is about 1/3, and serum albumin, globulin in this and the blood of human body are in similar proportion; The globulin that is contained is a kind of mixture of Y one globulin, has antibiotic, antiviral, function in delaying senility; 21 seed amino acids that contain; 8 kinds of essential amino acids wherein; The vitamin more than 16 kinds that the activity that contains is very strong, wherein the abundant acetylcholine of content can not only memory reinforcing, and can slow down aging.Also contain phosphate cpd in addition, various trace elements, enzyme, micro-hormone, peptide growth factor, these materials can promote cellular metabolism more all sidedly, division and regeneration.Old and feeble cell is upgraded, thereby make people's longevity.The agent of royal jelly nutritive composition is complete, can carry out comprehensive nutrition to human body, makes whole machine body obtain upgrading, thus delaying human body caducity.

3, sexual function improving: contain promoting sexual gland hormone in the Lac regis apis, can make the effect that the sexual centre youth is everlasting.Sexual hypofunction at first is that aging takes place sexual centre, influences the genitals, produces various sexual dysfunction.Lac regis apis can be had an effect at sexual centre, plays the effect that prevents sexual disorder and strengthen its function.Experiment is proof also, and Lac regis apis can also directly stimulate genitals and relevant organ to strengthen its function.Lac regis apis has more significant effect aspect recovering and strengthening women's sexual function.Experimental result proves that Lac regis apis can improve motility of sperm, and this is the cause that adenosine triphosphate (ATP) and sugar have offered the sperm motility energy.

The foreign scholar once experimentized with the back 21 days mice of birth in zoopery, find that Lac regis apis is accelerated its follicle maturity, and the promoting sexual gland hormone effect was proportional with injection Lac regis apis dosage.

According to another report, Japan medical science is discovered, contains a large amount of vegetalitas sexual cell pollen in the Lac regis apis, and it is made up of a kind of and the similar phytohormone of the pituitary hormone people.The plant characteristic that significantly enlivens gonad is arranged.And the sugar of Mel is very useful to the formation of seminal fluid very easily by blood absorption.The aspartic acid that contains in the Lac regis apis is the main matter of " helping property ", and it also has the growth of promotion, and sexual function improvement stimulates reproductive performance.The enhancing body resistance,, anti-senility effective ingredient neural with hemopoietic function and adjusting enhance metabolism.Because of weak, old sexual hypofunction person, can adhere to taking Lac regis apis.

4, antioxidation: modern study shows that Lac regis apis contains abundant superoxide dismutase (SOD), the cofactor of antioxidant reductases such as peroxidase antioxidases such as (CAT) and zinc, copper, manganese, and Lac regis apis also can significantly improve the SOD activity.Antioxidants such as the vitamin A that Lac regis apis also contains, C, E, B and trace element-selenium have good antioxidation, avoid the infringement of free radical with the protection human body cell.

5, nourishing the brain and improving intelligence: studies have shown that edible Lac regis apis can make brain obtain prescribing adequate nutrition, improve people's computing capability, ability of thinking and tap intellectual resources.Particularly the academic dress before the examination with Lac regis apis after, feel that all the clever order of ear is intelligent, quick-minded, energetic, hypermnesia, biotonus also obviously relaxes.In a word, the royal jelly nutritive composition is comprehensive, balanced proportion, and the effect of its nourishing the brain and improving intelligence not only is its distinctive composition, but the comprehensive function of its comprehensive nutrition.Often taking Lac regis apis can not only have good health and a long life, and nourishing the brain and improving intelligence also is of great benefit to, and is the nutrition brain, improves the good merchantable brand of intelligence.

6, skin maintenance: Lac regis apis is a kind of natural high tonic, and it not only has medicinal health care function, also has skin protection, and nutrition beautifies skin and prevention, treats dermopathic cosmetic result.By adjusting nursing skin from inside to outside, reach the effect of skin maintenance to the nourishing of whole body with to the inside of human body.

Why Lac regis apis can have the beautification function of mystery like this, theory of Chinese medical science according to " in elegant outer must the supporting ", the analysis showed that, the protein that contains needed by human in the Lac regis apis, aminoacid, vitamin, trace element, enzyme, lipid, saccharide, hormone, phosphate cpd etc., also have some unknown compositions, these abundant nutritions have the effect of beauty treatment, as contained peptide growth factor, can promote cellular metabolism, division and regeneration more all sidedly, old and feeble cell is replaced by new cell.In a word, the royal jelly nutritive composition is complete, easily is absorbed by the body, and regulates the body metabolism, health invigorating, and life lengthening, and can promote and strengthen the vitality of epidermis cell, and improve the metabolism of cell, prevent the effect of dermatosis and skin maintenance.

7, hepatoprotective: experimental results show that, Lac regis apis has liver protection functions such as the hepatocyte growth of promotion, to the hepatocyte results verification that experimentizes, the contained native protein of Lac regis apis has the hepatocyte of promotion DNA (deoxyribonucleic acid), suppress cell " suicide " and wait liver protection function, its function and hepatocyte growth factor (HGF) are suitable.

8, promote hemopoietic: oral or injection Lac regis apis, erythrocytic diameter is increased, and amount of hemoglobin and skein cell number are increased, find that also the patient takes in the Lac regis apis 24 hours, iron content significantly increases in the blood.Studies have shown that this is owing to the result who stimulates Railway transportation to fail, and erythrocyte and hemoglobin increase obviously all, number of platelets also increases.When experiment showed, to the oral Lac regis apis of mice, can prolong the life span of mice, the control group mice mean survival time is 6.5 days, and the Lac regis apis group mice mean survival time then is 13.9 days.Latter's life span prolongs 1 times than the former.And Lac regis apis can also alleviate the inhibitory action of 6-MP to bone marrow, shows that Lac regis apis has protective effect to myeloid tissue, can excited hemopoietic function of bone marrow.

9, anticancer: a large amount of evidences, Lac regis apis have certain antitumaous effect.Zoopery proves, the inhibitory rate 75.83% of Lac regis apis, and the body weight gain of mice is very fast in experimentation, begins a little less than the inhibition to tumor in several days, to inhibitory action enhancing in mid-term.By inference, may be to take Lac regis apis after a period of time, improve body's immunity, thereby suppressed the growth of tumor cell.It is reported the Jiangsu Inst. of Traditional Chinese Medicine research worker,, found that generally reflection takes back improvement person's 1279 examples, account for 93.7% with Lac regis apis lyophilized powder (LRP) treatment 1365 routine malignant tumor; Appetite enhancer 1174 examples account for 86%, merge the side effect that the chemotherapy and radiation person can alleviate chemicotherapy, are that the patient can adhere to finishing the course of treatment.

In addition, Lac regis apis also has antimicrobial antiphlogistic, the Radiological Defense heart, and blood pressure lowering, the blood fat reducing blood sugar lowering promotes tissue regeneration, improves effects such as sports achievement.

(6) hide Rhizoma Polygonati: (Huang jing), for my year living Liliaceae is planted the dry rhizome of taxi.Property is done, sweet in the mouth, is returned spleen, lung, kidney strong.Effect with spleen reinforcing yin nourishing, spleen invigorating lung moistening, the kidney invigorating.Be used for that weakness of the spleen and stomach, body void are weak, mouthfeel lack of appetite, the dry larynx of the deficiency of the lung.Be longer than invigorating the spleen and replenishing QI, the foster taste of benefit, sick body void, weakness of the spleen and stomach, xerostomia lack of appetite, asthenia of essence and blood.The Compendium of Material Medica record: the Rhizoma Polygonati QI invigorating is transferred smart, gentle, the muscle sufficiency of the five internal organs.Have not old for many years, the blackening of turning white, dedentition and give birth to effect.Modern pharmacological research, Rhizoma Polygonati effectively blood pressure lowering and blood glucose can increase the symptom blood flow volume completely, play blood fat reducing and delay arteriosclerotic effect.

Chemical constituent: mainly contain polygonatum polysaccharide class, steroid saponin, flavone, several amino acids, alkaloid, mannitol, lymphatic temperament, flower quinones etc.

Pharmacological action: 1, improve immunity: discover that Rhizoma Polygonati has the effect that strengthens the human T cell.Immune function of human body be can strengthen, DNA, RNA and proteinic synthetic promoted.Lymphocyte transformation to the immunologic hypofunction patient has excitation.Compound recipe can make mice breast arteries and veins weight show to be increased, and can improve the humoral immunity level of thin breast sum of animal spleen T and external source thymus-dependent antigen, strengthens cellular immune function.Mice is wrongly taken coarse solomon's seal polysaccharide 400mg/kg, can obviously strengthen thymus and spleen weight after 7 days, obviously strengthens wind shape endothelium and does not unite to the phagocytic activity of india ink.

2, antioxidation: Rhizoma Polygonati can improve the free radical ability.The Rhizoma Polygonati decoct can obviously improve the content that superoxide dismutase activity in mouse red blood cell and the liver reduces cured brown matter in mouse cardiac muscle and the cerebral tissue.The Rhizoma Polygonati oral liquid can significantly reduce the heart, liver lipid oxidation thing (LPO) generates, and increases superoxide dismutase, and the paddy Guang is peptide peroxidase (GSH-P) vigor and the super oxidation synthase of blood vigor.Show that Rhizoma Polygonati can obviously improve body free radical resisting ability, to suppressing the effect that LPO generates the tool uniqueness.Coarse solomon's seal polysaccharide can reduce mda content in the carbon tetrachloride poisoning murine liver tissue, has anti-matter and refers to peroxidation.

3, defying age: wrongly took decoct 27 days to mice, can obviously reduce myocardium lipofuscin content and improve the liver SOD activity, the lipid peroxidation that the protection free radical causes has anti-aging effects to the infringement that biofilm structure and function cause.Wrongly take Rhizoma Polygonati 6g/kg to mice, the activity of 10 days erythrocyte Na+ that can raise, K+-ATP enzyme.Polygonatum polysaccharide promotes mouse lymphocyte conversion ratio, erythrocyte, crystal nuclear, lens cortex superoxide dismutase SOD activity.Water decoction 2.59g/kgd, 3g/kgd can make skin hydroxyl dried meat amino acid content increase by 6.6% in 1 month for the mice gastric lavage, significantly improved lactic acid dehydrogenase activity and brain homogenate catalase activity in cardiac muscle and the cerebral tissue, can obviously improve the mice hypoxia-bearing capability.The telomerase activation of old and feeble people Mus brain, the gonadal tissue of can significantly raising.

4, antipathogen: experiment in vitro shows that the Rhizoma Polygonati water decoction is to Bacillus typhi, and golden yellow or the like coccus, acid-fast bacilli and adenovirus and cancer virus have inhibitory action.Tuberculosis is had notable therapeutic effect, and curative effect is carried nearly isoniazid.In addition multiple fungus also there is inhibitory action.

5, improve adrenal cortex function: Rhizoma Polygonati has the effect that suppresses adrenal cortex function, and caused fat, neat random the having some improvement of carbohydrate metabolism are advanced by adrenal cortex unit.

6, the liver protecting: coarse solomon's seal polysaccharide can obviously reduce the mda content in the CCI4 poisoning mice hepatic tissue, has lipoid peroxidization resistant.

7, resisting fatigue: the Rhizoma Polygonati water decoction is wrongly taken mice and is carried out the swimming test result and show, mice prolongs at the frozen water swimming time, can strong mice muscle power and to stressed condition down opposing can, have remarkable antifatigue effect, it is relevant that the many low thighs of this effect cause kinases (CK).Rhizoma Polygonati also has good anti-tubercle bacillus to do in addition, thereby is fabulous tonification anti-fatigue product.

8, anti-hypoxia: experiment shows, the Rhizoma Polygonati water decoction is wrongly taken and can be improved mice and survive under anoxia condition and utilize ability, to increase often anti-sound when scarce.Significantly improve lactic acid dehydrogenase activity and brain homogenate catalase activity in cardiac muscle and the cerebral tissue, can obviously improve the mice hypoxia-bearing capability.

9, radioprotective: polygonatum polysaccharide can obviously resist the minimizing of 6 ℃ of gamma ray induced mice peripheral leukocytes and total number of blood platelet, can obviously improve irradiation mice peripheral red blood cells C3b receptor rosette rate and immune complex rosette rate.

10, coronary artery dilating, anti-scheming ischemia: experiment showed, that Rhizoma Polygonati can make rat heart thigh contractility obviously strengthen, the coronary disease mistake flow that exsomatizes is obviously increased.Intravenous injection have the antagonism pituitrin due to the effect of acute heart thigh ischemia.

11, anti-leukopenia: polygonatum polysaccharide can the cruel amine of bright antagonism ring phosphorus institute reduce to locating the mice peripheral blood leucocyte, the mouse spleen weight of immunocompromised is increased, its leukogenic effect may be the hypertrophy by the spleen Interstitial cell, and performance compensatory marrow is made its function outward.

12, blood fat reducing: exempt to take 100% decoct 10ml/d to hyperlipidemia, 30 days, can obviously reduce trigalloyl oil-beta lipoprotein, cholesterol (TC), alleviate aorta wall speckle and crown arteriosclerosis.Exempt to take polygonatum polysaccharide 1.6ml/gkd to hyperlipemia, can obviously reduce serum LDL-C, LP (a), TC concentration and minimizing, the aortic tunica intima foam cell forms.

13, blood sugar lowering: polygonatum polysaccharide 500/kg, can significantly reduce epinephrine, model mice blood glucose and liver CAMP content.Extractum and methanolic extract can suppress the glycogen alcoholysis, to adrenal gland, chain urea toxin bring out blood sugar increasing mice, exempt from that the obvious functions of blood sugar effect is all arranged.

14, tuberculosis: water decoction is external to have the obvious suppression effect to tubercule bacillus.

(7) hide the Radix Astragali (Mik vetch), be the root of the leguminous plant Radix Astagali or the Radix Astragali.Warm in nature, sweet in the mouth.Go into spleen, lung meridian.Have effects such as invigorating QI to consolidate the body surface resistance, nourishing blood and promoting granulation, diuresis, poison holding.

Chemical analysis: mainly contain Radix Astragali triterpene soap class, polysaccharide, Saponin, flavone, 19 seed amino acids, compositions such as protein, trace element.

Pharmacological action in: 1, enhancing immunity: astragalus polysaccharides can obviously increase mouse spleen, the thymus quality, to spleen due to the loose dragon is arranged by force, the thymus quality alleviates that tangible antagonism is arranged.Can make T cell number increase in mouse thymus and the spleen in addition, promote the generation of 1gG.Can strengthen the activation of human lymphocyte Turnover of Mouse Peritoneal Macrophages and neutrophilic granulocyte.Complement after cobratoxin is handled is descended, and the Cavia porcellus that phagocytic rate descends has the reparation of the complement of promotion, promote neutrophil cell raising and restore funcitons such as to engulf.Astragalus decoction can improve the regulating power of macrophage, T lymphocyte, bone-marrow-derived lymphocyte etc.And can obviously improve and specific immune function, body immunity at night, cellular immunization etc. are all had promote and potentiation that EVAC is had tangible stimulation, have and self induce, promote to induce and active volatilization.

2, antioxidation: the generation of oxygen-derived free radicals when Radix Astragali total flavones 10mg/kg can reduce the rat heart muscle ischemia.Radix Astragali total saponins 37.54g/ml adds the heart thigh that exsomatizes and preserves in the liquid, cardiac function and coronary flow are obviously strengthened. according to another report, flavone in the Radix Astragali has anti-radical action, and free radical is one of tumorigenesis disease factors such as mutagenesis. and research worker is fallen the interior free yl level with flavone.Make its metabolism environment that destroys people's struma, reduce the accretion rate of tumor and suppress the swollen cell speed of growth.

3, slow down aging: with A PS200mg/kg lumbar injection, mouse spleen is enlarged markedly, the increase of RND content reaches about 18%, can prolong cell survival, strengthens cellular metabolism, postpones aging.Astragalus polysaccharides has direct removing lipid peroxide (LPO), and SOD activity improving has good protective action to the rabbit aortic smooth muscle cells (SMC) of In vitro culture because of the damage that free radical causes, the aging and effect such as sclerosis grade of control arteries.With fibrocyte in the human embryo lung (HEL) diploid of In vitro culture is the experiment die body, measure cell survival, the strong ability SOD content of training, test group can be grown for 77 generations as a result, and matched group was only lived for 52 generations, the same generation ability of cell proliferation in age, SOD content and generation time-to-live all are higher than matched group.Astragalus polysaccharides can make in the old rats cell SOD contain obvious rising (150mg/kg P＜0.01) the anti-old and feeble effect of prolonging has been described.Astragalus polysaccharides can obviously reduce the reason that contains of lipid peroxide in the rat plasma, and the deposition of lipofuscin is to cause aging organ balance to be decreased a kind of factor, and it and age are linear increase sexual relationship.

4, prevent and treat cardiovascular disease: polysaccharide that from Radix Astragali stem, leaf, extracts and saponin; through 17 of physiologys, biochemical, morphology index consistent showing; to the heart of the acute myocardial infarction dog myocardial contraction that changes; dwindle myocardial infarction area, alleviate effects such as myocardial damage; and can further cause the rabbit ventricle to reduce the minimizing of heart throughput rate, reduce myocardial oxygen consumption and protection ischemic myocardium.

5, protection spleen: astragalus decoction, astragalus polysaccharides, astragaloside etc. are to chmice acute, CC14 toxic hepatitis; the endotoxicosis hepatic injury; hepatic injury such as galactose, acetic acid phenol; all can alleviate pathological changes and death that the liver poison causes, its mechanism is relevant closely with the adjusting metabolism with the antibiont oxidation of the Radix Astragali.The Radix Astragali can prevent that glycogen from reducing anti-hepatic injury in addition.

6, improve sleep: astragaloside and water decoction irritate stomach or abdomen is annotated, and the mice autonomic activities is reduced, and prolongs the lengths of one's sleep such as barbital, reduces fistfight.

7, bone density improving: decocting liquid gavaged the osteoporosis type rat to being caused by hydrocortisone in 5g/kg60 days, can make the bone formation rate increase by 100%, the bone trabecula area increases by 37%, gavages in aqueous extract 5g/kg12 week effectively to stop the bone loss of removal ovary rat.

8, antitumor:; Astragalus polysaccharides is to the human lung adenocarcinoma of tumor, hepatocarcinoma, nude mouse in the mice, and the strain of human colon carcinoma dehydration oncocyte tumor all has the obvious suppression effect, and the inhibition ratio of outflow is 20%-51%, and to the mouse entity melanoma, effective tumour inhibiting rate of pulmonary carcinoma is 20%-47%.According to another report, Radix Astragali water extract 100g/ml reaches 94.94%. to the suppression ratio of human stomach cancer cell line AGS

9, skin Caring: the Radix Astragali can strengthen skin-nourishing and skin antibacterial ability, prevents skin aging, promotes hair growth, and is anti-loss.Contain the trace element of several amino acids and needed by human etc.Effect with skin nutrition promotes skin metabolism, improves skin resistance, makes skin delicacy, fitness.

10, control is dull-witted: it is reported, Japanology studies show that, research worker is raised the animal suffer from senile dementia with Radix Astragali extract, found that and can significantly improve its cognitive competence, gives patients of senile dementia the oral obvious effects that obtained the capsule of heavy dose again subsequently.Studies show that this natural drug truly has smelting to treat the effect of degeneration cerebral diseased.

11, defying age.After senile rat is taken astragalus decoction, can obviously reduce collagen content in its aorta and the lung, make it near young rat, prompting is taken the Radix Astragali for a long time prevention senile arteriosclerosis, the old and feeble pulmonary function of improvement is had the certain significance.

12, the metabolic influence of pair cell.The Radix Astragali can obviously delay human embryonic lung diploid fibroblast naturally-aged process, can prolong cell survival about 1/3; Healthy human lymphocyte silk division has inhibitory action to In vitro culture in high concentration, and facilitation is then arranged during low concentration.

13, to the influence of nucleic acid metabolism.Astragalus polysaccharides has the effect of antagonism mercurial, and the ribonic acid enzyme of body and inhibitive factor balance sysmte thereof are kept normally; To mouse peritoneal injection 200mg/kg the effect of remarkable inhibition liver, spleen alkalescence ribonucleic acid enzyme activity is arranged, but serum and acid core ribonuclease T. are not had obvious effect.

14, to proteinic influence.Astragalus decoction continuous irrigation stomach 10 days can significantly increase the speed that the 3H-leucine mixes serum, hepatic protein, and Protein content not had influence, thinks that the Radix Astragali can promote mice serum and the proteinic renewal of liver, and effective ingredient may be a polysaccharide; And astragalus saponin 1 also has similar effect.

15, to the influence of blood glucose.Astragalus polysaccharides 250～500mg/kg injects to mouse peritoneal, has the effect of two-ways regulation blood glucose, and Fructus Vitis viniferae load back mouse blood sugar level is significantly descended, and the mouse blood sugar rising reaction that can obviously cause antiadrenergic drug; And phenformin is caused mouse experiment hypoglycemia obvious antagonism is arranged, and islets of langerhans disposition hypoglycemia is not had obvious influence.

16, mutation.Astragalus decoction has significant inhibitory effect to the bone marrow cell micronucleus permillage and the rising of chromosomal aberration percentage rate of the mice active somatic cell that aflatoxin B1 brings out, and along with increasing of dosage, more remarkable effect is situated between and the incomplete mutagenic action that suppresses aflatoxin B1.The mechanism of action of Radix Astragali mutation in living animal may be protected cell with its effective ingredient, and raise immunity and promotion DNA are synthetic, and the injury repairing effect of strengthening DNA is relevant.

17, blood pressure lowering.The Radix Astragali is given rabbit, dog, cat intravenous injection, and hypotensive effect is all arranged, and wherein Gamma-propalanine content is almost completely parallel with the hypotensive effect power, may be the effective ingredient of blood pressure lowering.The Radix Astragali has many-sided effect to spontaneous hypertensive rat, can make its many indexs be tending towards normal level.Astragalus polysaccharides has the blood glucose of raising and strengthens the metabolic effect of human body cell reproduction, to blood sugar level dual regulation in the body.

18, beauty treatment.The main component of the Radix Astragali (be divided into polysaccharide, the liquor-saturated alcohol of-paddy steroid, trace element and choline, folic acid etc. though the merit of QI invigorating is inferior to Radix Ginseng, are sent out because of its this property of medicine is kind, walk table flesh, can be better with the Radix Astragali in beauty treatment side.Modern study shows that the Radix Astragali has enhancing and adds effects such as promoting organism metabolism.

19, to the influence of blood system.Astragalus decoction causes the pressure drop of hemolytic blood deficiency zooblast low to this hydrazine of acetyl, and the blood specific viscosity reduces, and the erythrocyte electrophoresis rate reduces, and electrophoresis time prolongation etc. all has the improvement effect.It is hemopoietic function that the Radix Astragali injection lumbar injection can strengthen the normal mouse grain, and making the single grain of bone marrow is that the CFU-GM number is apparently higher than matched group; Caused by cyclophosphamide rat marrow hemopoietic function there is obvious protective effect unusually, can stops the obvious minimizing of bone marrow nucleated cell number.Hairy Root of Astragalus membranaceus gavages, can improve RBC number, the reticulocyte counts of hemorrhagic anemia mice, increase RBC number, hemoglobin value, the packed cell volume value of hemolytic anemia mice, can resist the decline of the leukocyte count and the bone marrow nucleated cell number of cyclophosphamide, X ray induced mice, the effect that promotes the hemopoietic system function is arranged.

20, protect kidney: the Radix Astragali injection intravenous injection can make the serum albumin of rat MCN model obviously raise and can increase the blood fortune of glomerular capillary silk; To rabbit mesentery productive nephritis, can obviously reduce glomerular mesangium district IgG and C3 deposition.The Radix Astragali can significantly reduce proteic amount in the urine, alleviates the nephropathy degree.The mechanism of the Radix Astragali treatment nephrotic syndrome improves seralbumin concentration, thereby improves its clinical manifestation for promoting to suffer from the protein synthesis of body.

21, diuresis.The Radix Astragali has medium diuresis, human trial declines bright, this product can increase the urine amount and oxide is drained, give clinical dosage urine amount o.2g/kg and can increase by 64%, the diuresis persistent period of row's sodium amount increase 14.5%. Radix Astragali is longer, after giving rat skin lower injection, the generation that has no drug resistance after 7 days of sustainable 7 days of diuresis, successive administration.

22, resisting fatigue, astragalus polysaccharides 250-500mg/kg lumbar injection, but " yang deficiency " mice room temperature swimming time due to significant prolongation normal mouse and the hydrocortisone, and increase mice adrenal gland weight under the stress state.

23, anti-hypoxia.Radix Astragali oral liquid 20～50g/kg irritates stomach, astragalus polysaccharides 280～500mg/kg lumbar injection all has remarkable antagonism to the mice normal pressure of normal and isoproterenol processing and the cerebral anoxia due to decompression anoxia, cyanide poisoning anoxia and the ligation bilateral carotid, and can obviously prolong mice has live time.

24, cold-resistant.The astragalus polysaccharides lumbar injection can obviously strengthen low temperature resistant (5 ℃) ability that normal mouse, hungry mice and oxidation cortisone are handled mice, and its life span is obviously prolonged, but does not have obviously high temperature resistant (45 ℃) effect.

25, radioprotective.Astragalus polysaccharides can impel the spleen tissue structure of the mice damage behind the radiation exposure obviously to recover, and improves the super emblem structure of spleen endolymph cell, improves the activity of succinate dehydrogenase in the peripheral blood lymphocyte.And the Ultrastructural change of regulating liver-QI falls in mice weight loss, leukocyte count due to right-60 ℃ of irradiations now all obvious protective effect.

26, antiviral. astragalus decoction has direct inactivation of viruses effect, and can suppress the cytopathy behind the infective virus, can directly suppress chickenpox one varicella zoster virus, and the virus of duplicating is had the growth inhibited effect.Radix Astragali injection has certain blocking effect to the course of infection of epidemic haemorrhagic fever virus in the mice neonatal rat body according to another report.The Radix Astragali has antivirus action or has the function that the protecting myocardial cell rabbit is subjected to the virus infringement, and the experiment in vitro Radix Astragali comprises HIV (human immunodeficiency virus) quite under the concentration inhibition virus function being arranged.

27, anti-pulmonary hypertension. the Radix Astragali has obvious resistance inhibitor action to pulmonary artery configuration reorganization in rat hypoxic pulmonary hypertension and the hypoxia gonad bubble; show as pulmonary arterial wall cell in the protection acinus; suppressing vascular smooth muscle cell curing, hypertrophy and extracellular matrix increases; reduce increasing of blood vessel wall adventitia fibroblast and collagen fiber, the tiny arterial lumen of lung that expansion is shunk because of anoxia

28 calmness.The mouse subcutaneous injection Radix Astragali can be kept a few hours sedation. and the Radix Astragali 10%, 30% water decoction drank for mice continuously 15 days, can suppress exploratory behavior activity of mice wilderness and spontaneous activity, and energy antagonism pentobarbital sodium, prolonged the length of one's sleep of chloral hydrate.

29 analgesias.Mouse writhing method and hot plate method experiment show that astragalus saponin 1 and sheep astragalin have obvious analgesic activity.

30, increasing intelligence. Radix Astragali decocting liquid drinks or irritates stomach to mice, the effect of strengthening learning and memory of little mouse is arranged, and helps the storage of mouse brain to information.

31, antibiotic.To dysentery bacterium, anthrax bacillus, a-Streptococcus hemolyticus, Beta-hemolytic streptococcus, diphtheria corynebacterium, bacillus pseudodiphthericus, Diplococcus pneumoniae, staphylococcus aureus, Staphylococcus citreus, Staphylococcus albus and bacillus subtilis etc. have antibacterial action to the Radix Astragali external.

32, antiinflammatory. astragalus saponin 1 irritates stomach or 5mg/kg intravenous injection for rat 50mg/kg all can be increased the rat capillary permeability that antihistamine and 5-hydroxy tryptamine cause.25～100mg/kg irritates stomach, can significantly resist the rat paw edema that carrageenin causes, its suppression ratio is linear in this dosage range.

33, hormone-like effect.Radix Astragali extractum, Radix Astragali lactone and Radix Astragali sterin are to rat. and weight such as the body weight of mice, levator ani or kidney all do not have obvious influence, showing no anabolic hormone or the effect of androgen sample. the Radix Astragali can make mice obviously continue 10 rutting period, and estrogenic promoting action is arranged.Water extraction of astragalus membranaceus can suppress the bone resorption of removal ovary rat, has function of resisting osteoporosis.

(8) Tibet Fructus Hippophae (Seahuckthorn) is Qinghai-Tibet a kind of wild plant one Fructus Hippophae of growth more than 3000 meters.Because Qinghai-Tibet Special geography ecological environment and weather conditions, high and cold anoxia, sunshine-duration are long, and day and night temperature is big, bred to have special bioactive substance content and enrich, and be the top grade of other various places Fructus Hippophae.Fructus Hippophae looks for " angle fruit " in the Tibetan that lives in the Qinghai-Tibet Platean, and extremely strong medical value is arranged.At Tibetan medicine's monumental work Four-Volume Medical Code and " Qinghai-Tibet medicine history " argumentation is arranged all.It is the medicine food dual purpose plant that Ministry of Public Health is announced.

Modern medicine research is thought, the Tibetan medicine Fructus Hippophae has health invigorating, regains one's strength, allaying tiredness, refreshing spirit, patient myocardial ischemia anoxia, defying age, anti-strong, blood pressure lowering, prevent and treat arteriosclerosis, cerebral thrombosis has better prevention and pharmacological action, modern clinical with cholesterol reducing, enhancing myocardial flow, improve arrhythmia etc.

Chemical constituent: Fructus Hippophae contains 14 kinds of vitamin, abundant vitamin C, E, A, B1, B2, folic acid, calcium, carotene, flavone compound, alkaloid, 20 several amino acids, unsaturated fatty acid, monosaccharide, 12 kinds of organic acid, 32 kinds of trace element especially contain abundant superoxide dismutase more than 200 kind of bioactive substances to the human body beneficial such as (SOD).Be described as " Bao Ku of vitamin " by the expert of China and foreign countries.

Pharmacological action:

1, raise immunity: but Oleum Hippophae and juice of Fructus Hippophae enhance immunity organ weight improve the serum half and hold blood value antibody titer and antigenic stimulus antibody titer once more.Promote macrophage phagocytic function.Similar juice of Fructus Hippophae of the effect of Fructus Hippophae flavone and Oleum Hippophae, and the mice serum antibody horizontal of immunologic hypofunction is raise.

2, resisting fatigue, anoxia enduring: evidence, Fructus Hippophae total flavones have the myocardial nutritional flow amount of increase, improve myocardium microcirculation, reduce myocardial oxygen consumption, have resisting fatigue, anoxia enduring, effects such as cold resistant and mutation.

3, antioxidation: Fructus Hippophae extract can significantly reduce hyperlipemia and cultivate the LPO content that increases in the smooth muscle clearly, suppresses LPO rising in the mice serum of ozone damage back, improves the activity of superoxide dismutase.Fructus Hippophae total flavones generates O to the PMA dysmorphocaryocyte ²-there is significant dosage to rely on scavenging action.The sea buckthorn juice gastric infusion can obviously strengthen normal tumor-bearing mice GSH-PX activity, reduces lipid peroxide contents.According to another report, Fructus Hippophae total flavones to the removing ability of active oxygen greater than vitamin E.Oleum Hippophae 2.5mg/kg, mice abdomen annotate or rat is annotated clothes, can obviously reduce the state LPO of cardiac muscle etc., SOD activity improving.

4, slow down aging: Fructus Hippophae can obviously prolong the life-span of wild oily Caulis et Folium Lini fly.

5, antitumor: Hippophae (rhamnoides) original juice has certain inhibitory action to tumor cell proliferation in the mouse ascites; DNA in bone marrow cells in mice, people's acute myeloblastic leukemia cell, the mouse lymphocyte there is the obvious suppression effect; to the mechanism of leukemia cell growth inhibition may with to the synthetic depolymerization of DNA with suppress synergistic effect, can watch for animals and avoid the damage of N-nitrosodimethylamine.

6, the liver protecting: studies show that Oleum Hippophae 2.25-4.50g/kg * 3d mouse gavaging or 0.84-1.68g/kg sea buckthorn juice can be protected CCL4, the hepatic injury due to the acetaminophen.

7, resist myocardial ischemia and cardiac muscle not normal: the Fructus Hippophae holomyarian divides abdomen to annotate or quiet notes; mice rat acute myocardial ischemia is had protective effect; make arrhythmia reduce to 0 from 100%; Fructus Hippophae total flavones can increase the myocardial nutritional flow amount to mice, rat, Cavia porcellus; the antagonism ischemic arrhythmia; improve myocardial ischemia, promote cardiac function, angina pectoris effective percentage 94%

8, looks improving and the skin nourishing: studies show that; Fructus Hippophae contains nutrient substance such as abundant vitamin, C, E, A; but nutrition skin care; promote the regeneration of cellular metabolism and epithelial tissue, have antioxidation, antiallergic, dispel macula lutea, antibacterial, delaying decrepitude of skin etc., the effect of protection skin natural colour.

9, protection gastric mucosa: the glucosides 12mg/kg such as cupreol-β that hippophae rhamnoides seed extracts, the mouse gastric ulcer that acetic acid is brought out has protective effect.Oleum Hippophae rats gavaged 5mg/kg, the antagonism reserpine gastric ulcer.

10, blood fat reducing: Oleum Hippophae, flavone can make T-CHOL in the hyperlipidemia rats serum, and the total cholesterol level in triglyceride levels decline and the hepatic tissue descends, and serum middle-high density albumen (DHL-C) content is raise.

11, antithrombotic: Oleum Hippophae can make rabbit experiment thrombosis postpone, and has prevention thrombosis and certain anticoagulation.Its effect is to participate in intrinsic coagulation system, obviously reduces fibrinogenic content, and this is relevant with fatty acids in the Oleum Hippophae.

12, to the effect of hematopoietic cell: Hippophae (rhamnoides) original juice has its growth effect of promotion to hematopoietic cell, and this effect may to be rich in vitamin C, E, A and each seed amino acid relevant with Fructus Hippophae.

13, promote growth promoter: Fructus Hippophae concentrated fruit juice vitamin C can promote brood (Cavia porcellus), growth promoter.Hypovitaminosis C there is therapeutical effect.

14, antiallergic: the Fructus Hippophae flavone lumbar injection can suppress the mice passive cutaneous anaphylaxis, PCA, its anti-allergic effects link may not improved target organ pipe and cell effect, also play a role unlike medicines such as Piao Ermin competition receptor in target cell, may be relevant with factors such as antigenic combination of inhibition or medium releases.

(9) Sargassum extract (Sea weed) is the frond of Sargassaceae Brown algae, comprises the dwell dry body of Lay and Sargassum of sheep, has hard masses softening and resolving, expectorant diuretic function.Modern medicine study has blood fat reducing, blood sugar lowering, fat-reducing, improves looks, enriches blood, toxin expelling, protect the liver, function such as antitumor, antiviral.

Chemical analysis: mainly contain Sargassum polysaccharides: the sheep Lay Polysaccharide A of dwelling, the sheep Lay polysaccharide C of dwelling, sargassan etc.24-ethylidenecholest-5-en-3.beta.-ol., saringosterol, iodine, ferrum various trace elements, aminoacid, multiple nutrients materials such as unsaturated fatty acid.

Pharmacological action: 1, regulate immunity: experiment shows: Sargassum polysaccharides can improve mouse boosting cell DHA synthesizing activity, and the cytophagous digestion activity of anti-staphylococcus aureus has facilitation, to cytokinesis.Discover that further Sargassum polysaccharides also has facilitation to the generation of splenocyte polyclonal antibody (IM and IgG).Sargassum polysaccharides can strengthen specific immune function and non-specific immunity, strengthens the phagocytic activity of Turnover of Mouse Peritoneal Macrophages and the function of pair cell immunity and body fluid and humoral immunization.

2, protect the liver: Algin has certain preventive and therapeutic effect to hepatic fibrosis in mice.The control of hepatic fibrosis is the treatment chronic hepatopathy, the important channel that the control liver cirrhosis forms.Its mechanism is relevant with the adjusting immunologic function with its microcirculation improvement.

3, enrich blood: Sargassum contains abundant organic iron element, and for general rich ferrum food 20 times can effectively strengthen hematopoietic function, and to severe loss of blood, low sanguinin anemia and iron deficiency anemia have significant curative effect.

4, beauty treatment: Sargassum contains a large amount of chlorophylls, vitamin A, vitamin E, vitamin B group and bioactive ingredients, to promoting skin cell metabolism, preventing athero, pigmentation and xerosis cutis, keratinization, delaying decrepitude of skin, alleviate the preceding syndrome of postmenopausal women, having taken the senile plaque of dispelling, chloasma effect for a long time, is ideal beauty treatment good medicine.

5, toxin expelling: Sargassum extract is the street cleaner of human body endogenous toxin material.Clinical trial shows, can remove human body and accumulate radiant, removes the toxic and side effects of important meals ion, virus and medicine in the human body.Suppress renal damage, its mechanism Sargassum contains the effect that abundant chlorophyll has absorbing toxin, can discharge harmful substance in the body.

6, antiviral: growth has the obvious suppression effect to red seaweed polysaccharide to bovine immunodeficiency virus, and its suppression ratio is respectively 85.96% and 88.63%.From the polysaccharide that little red algae is extracted, virus duplicating in parasitic cell can be stoped, and virus intrusion normal cell can be prevented effectively, to escherichia coli and viral infection, inhibitory action is arranged.

7, radioprotective: Sargassum polysaccharides can promote to be subjected to the recovery of radiation damage mouse hemopoietic system, strengthens the mouse anti radianting capacity, improves the activity of SOD in the mice whole blood, reduces the content of peroxide in the hepatic tissue, delays body aging.

8, antitumor: the proteoglycan (PPF) that extracts in the Sargassum is discovered ScaIettucET gonp in polysaccharide; When the content of polysaccharide was 50mg/kg, inhibition rate of tumor growth was 64.55%, and the leukocyte circulation reaches 65.11%.When the gonpi polysaccharide was 50mg/kg, life prolongation effect reached 18%-31%.Sargassum polysaccharides has strong immunoregulation effect to Turnover of Mouse Peritoneal Macrophages, may make one of its important mechanisms that suppresses tumor.The microalgae polysaccharide also has high inhibitory to S180, to the phagocytic function of mononuclear phagocyte, and the generation of mouse immune organ weight, spleen lymphocyte proliferation, the serum hemolysin effect that all is significantly improved.

9, fat-reducing: Sargassum extract was taken in preceding on the feed 30 minutes or 1 hour, but appetite-suppressing reduces appetite, made health obtain avoiding heat surplus, athero under the prerequisite of sufficient nutrition supply, reached the purpose of fat-reducing.

10, antioxidation: discover, extract low-molecular-weight fucoidan (LMSF) in the Sargassum, can directly eliminate oxygen anion free radical and hydroxy radical, SOD activity in remarkable enhancing serum and the tissue is also arranged in vivo external.

In addition, Sargassum extract also have blood fat reducing, blood sugar lowering, prevent constipation, control must angiopathy, effects such as blood pressure lowering.

(10) heart of a lotus seed is hidden the kernel that Semen Coicis extract (Cdi v seed) is a year and perennial grass undergraduate course plant SEMEN COICIS.Property is put down, sweet in the mouth.Has invigorating spleen for diuresis, the many effects of clearing away heat and discharging pus.Be used for diarrhea due to hypofunction of the spleen, edema beriberi, arthralgia, also be used for gastric cancer, uterus carcinoma, chorionic epithelioma, multiple Verrucosis etc.Modern medicine study and think that SEMEN COICIS has and fall effects such as knowing fat, blood sugar lowering, relieving constipation, fat-reducing, resisting fatigue.

Chemical constituent: mainly contain protein, fat, sugar, 8 kinds of essential amino acids, various trace elements such as linoleic acid, SEMEN COICIS blood ester, Semen Coicis element, polysaccharide, the V of B family, calcium, ferrum, zinc.

The effect of medicine: 1, enhancing immunity: the SEMEN COICIS extractum can suppress neutrophilic cell membrane, methyl conversion enzyme, phospholipase in the lymphocyte film, and the generation of the preceding parathyrine E2 and the oxygen of living, cell membrane has the antiinflammatory Stabilization.Gavage the three ester glycerol that extract in the unsaturated fatty acid to marmot, can make the interleukin-1 that cell produces in the tremulous pulse peritoneal exudate increase by 1.5 times, illustrate that exudate has the function that strengthens body immunity at night, contained neutral saccharide (glucosan 1-7) and acidic polysaccharose (CA-1, CA-Z) all have antibody activity.

2, improve sleep: the plain 100mg/kg of the quiet notes Semen Coicis of mice, can reduce automatic movable, 200mg/kg can make the electroencephalogram of rabbit the high-amplitude slow wave occur.100mg/kg, abdomen is annotated the Semen Coicis element, and to rat, mice all has sedation.

3, skin maintenance: SEMEN COICIS is the edible product of a kind of splendid beauty treatment medicine, and normal food can be protected human body skin gloss exquisiteness, and the elimination powder is perverse, freckle, senile plaque, cyasma, butterfly spot, to desquamation, acne chap, pachylosis has good effect.

4, suppress tumor: SEMEN COICIS alcohol extract, acetone extract abdomen notes have inhibitory action to the mouse ascites cancer, can prolong the survival period of mice.Water-alcohol extraction is 40%-50% to mouse entity cancer S180 hepatocarcinoma, H22 cancer suppressing ratio, and preventive effect is arranged, and proposes the last fortnight administration, and curative effect can improve 20%.50% alcohol extract can promote the squamous cell carcinoma cellular keratinization.Other has report, and SEMEN COICIS contains the very high two kinds of sitosterol of heart of a lotus seed alcohol B-Y of medical value, and these special composition have good protective effect on cancer risk.With 50 gram SEMEN COICIS, the wild Pedicellus et Pericarpium Trapae of 150 grams (the band shell cuts), pure cooking uses the development to cancerous cell such as gastric cancer, uterus carcinoma, skin carcinomas that inhibitory action is arranged.

(11) lycopene (LycoPene): lycopene belongs to the class carotene, and the tetraterpenes chemical compound is made up of 11 conjugation and two non-conjugated carbon two strandss.Mainly exist in the plants such as Fructus Lycopersici esculenti, Citrullus vulgaris, Fructus psidii guajavae immaturus,, claim lycopene owing to be from Fructus Lycopersici esculenti, to extract the earliest.Lycopene is kermesinus powder or oily liquids.Oil solution is yellowish orange.Water insoluble, be soluble in pure and mild oils and fats.Fusing point is 174 degree, and is flammable.Lycopene is comparatively stable in plant, the easy oxidation of pure product, and destructible under high temperature, acid, alkali condition does not have the activity of vitamin A.

Physiological function: 1, antioxidation: lycopene is cancellation singlet oxygen and the free radical antioxidation and the strongest carotenoid of defying age of all discoveries up to now, and its antioxidant effect is support one's family 100 times of E of a one, 5.32 times of a one carotene.Lycopene has significant elimination free radical and stronger oxidation resistance, is antioxidation and the strongest material of defying age ability that present occurring in nature exists.

2, sexual function improving: one studies show that, the male ate Fructus Lycopersici esculenti 5-10 time in one week, and the probability of suffering from carcinoma of prostate will reduce half.Because the position that intravital content of lycopene is high is a testis, prostate and adrenal gland, these positions and hormonal secretion have substantial connection, and hormone claims sexual function to be closely related.In some mediterranean countries, old man is still interesting to make love, and the carcinoma of prostate sickness rate of this area is also very low, is exactly because the contribution of Fructus Lycopersici esculenti.

3, control prostatosis: the concentration of lycopene in male testical and prostate is higher, but lower in suffering from the males of infertility, before this discover lycopene decision prostate health, prostatic lesion refractory why clinically.Find that according to modern scientific research prostatic variation is not a kind of disease, but old and feeble syndrome.Studies show that contain a kind of a large amount of active factors one lycopene in the prostate, this active factors is determining the normal performance of prostate function, so lycopene has tangible curative effect to prostatitic treatment.Lycopene also has the effect of the carcinoma of prostate of preventing and treating in addition.

4, improve male fecundity: studies show that, lycopene can effectively be treated male infertility, 30 ages of research worker random extraction are the male infertility patient of 23-45 between year, every day 2 oral lycopenes, each two milligrams, continue to measure in 5 months their sperm concentration, mobility and form, the sperm concentration and the vigor that found that them improve significantly, 30 patients' sperm concentration has improved, almost 3/4ths patients' sperm rises, and 63% patient's wife is conceived after experiment.According to another report, medical scientific is found, is given lycopene to the male patient who suffers from azoospermia and the weak disease of sperm motility, the intravital sperm quantity of patient after three months, mobility and sperm morphology all are significantly improved, and improve mankind spermatozoon quantity simultaneously and the vigor effect is remarkable.

5, suppress tumor: studies show that lycopene is by antioxidation, the inhibited oxidation free radical reduces tumorigenic danger.Confirmed now that to preventing preceding adenocarcinoma breast carcinoma, pulmonary carcinoma, gastric cancer are the most effective, and cancer of pancreas, colorectal cancer, esophageal carcinoma, oral cancer, uterus carcinoma are also had preventive effect preferably.To established tumor can make it to dwindle delay the diffusion, especially make carcinoma of prostate.According to the report of Harvard University, edible 10 times weekly, the danger of suffering from carcinoma of prostate reduces by 45%, 4-7 time weekly, can reduce by 20%, clinical research finds that lycopene can give protection against cancer, dwindle tumor, the tumor that slows down diffusion velocity is especially to carcinoma of prostate, breast carcinoma, pulmonary carcinoma and gastric cancer.According to the observation in 6 years of 4.8 ten thousand men, often eat lycopene (30mg/d) and suffer from the chance of carcinoma of prostate and subtract 34%.

6, blood fat reducing: studies show that lycopene can stop the oxidation of low-density lipoprotein cholesterol to destroy by antioxidation in vivo, thereby reduces atherosclerosis and coronary heart disease.Find that according to Dutch scholar's research measure carotenoid content in 66 non-lethality myocardial infarction patient subcutaneus adipose tissues, it is more remarkable that matched group is compared diversity ratio.Content of lycopene can be accepted exciting of different electronics, generates ground state oxygen or triplet oxygen lycopene, and one three heavy oxygen lycopene can be eliminated thousands of singlet oxygen free radicals, is 2 times of β-Radix Dauci Sativae.Therefore, tomato red have the effect that the protection biomembrane is avoided radical damage.

7, uvioresistant: when ultraviolet radiation skin, lycopene in the skin is at first destroyed, lycopene does not reduce 31-46% than shining skin in the skin, and β one carotene is almost constant, and this shows that lycopene has the stronger effect that alleviates tissue oxidizing damage.

8, improve bone density: lycopene can promote skeleton to grow up, form, and promotes the development of bone sprout cell, prevents the effect of bone-loss.It is reported that the Jia Nada medical clinical test proves that the natural tomato complex prevents bone-loss and promotes the active effect of bone sprout cell.Toronto ST, Michael hospital and University of Toronto find that in joint study lycopene has the effect that promotes the skeleton growth and form and promote the growth of bone sprout cell.Another research has shown that also tomato red have broken osteocyte formation and the active effect of destroying that stop.This explanation lycopene can prevention of osteoporosis.

9, control cardiovascular and cerebrovascular disease: it is reported that Dutch scientist discovers that the content of lycopene in myocardial infarction patient's subcutaneous fat is lower than healthy people.Experiment showed, that lycopene can suppress the biosynthetic speed limit of cholesterol and slow down the synthetic of cholesterol, can also reduce the oxidation destruction of low density lipoprotein, LDL (LDL), thereby can the prevention of arterial sclerosis and the generation of the basic heart, brain, renal vascular.

10, reduce wrinkle: discover that eat vegetable such as Fructus Lycopersici esculenti more and make the people seem young, wrinkle is few.According to German Le Monde, environmental effect such as solar radiation, harmful substances in air or stress and disease all can make and form the more freedom base in the human body, and these free radicals may damage the DNA in the skin again, thereby quicken skin aging.And the contained antioxidant of human body can be defendd the harm of free radical.Because human body can not form enough antioxidants, so human body need replenish proper quantity of antioxidant.Lycopene has good antioxidation to skin.

Discover that the people that oxidation preventive content is high in the skin looks young.In the personnel that the acceptance in 40-50 year detects, people's wrinkle that lycopene concentration is high in the skin is few.

11, speckle removing: studies show that lycopene tool skin care, the effect of elimination freckle.Lycopene can suppress melanic formation.Experiment showed, that lycopene can effectively reduce melanin and form.

12; the liver protecting: lycopene 10mg/kgBVC (low dose group) and 20mg/kgBVV (high dose group) are arranged after 4 weeks of rat gastric lavage; abdomen is annotated CCL4 to bring out acute liver damage (dosage is 0.5mg/kgBVV); post processing in 24 hours; measure serum; liver; the kidney homogenate is towards S Δ D; MDA; GSH-PX; GSH and totally dig oxidability (FA Δ D); compare with matched group; the SOD words property of two dosage and the active rising of GSH-PX; GSH content raises; the T-AOC ability rises; and MAD content reduces; be that lycopene can improve a large amount of oxidation resistances, alleviate the oxidative damage that CCL4 causes body.

In sum, this product has slow down aging, improves immunity, supports effects such as beauty treatment.

Processing technology:

1, allotment mixes: get the Tibetan Cordyceps extract, Tibet sheep placental extract, the Stigma Croci extract is hidden wolfberry fruit extract, hide the Lac regis apis extract, hide Rhizoma Polygonati extract, hide Radix Astragali extract, the Tibet Fructus Hippophae extract, sea bath extract, the SEMEN COICIS extract, raw materials such as lycopene mix, and stir.

2, capsule is filled: the raw material that stirs is sent into filling machine, raw material is filled in the capsule.

3, seal:, seal mouth by quality standard with populated capsule.

4, test package: the chewing gum capsule with sealing, be up to the standards, packing becomes formal product.

It is that raw material in the prescription is mixed by its physicochemical property that allotment mixes, and the operation that stirs.This operation gets raw mix, and it is that raw material is filled in operation in the capsule that capsule is filled.It is the operation that the capsule with populated raw material seals that capsule seals, and this operation is that this operation gets the semi-finished product capsule for raw material in the capsule is difficult for consuming and the capsule opening.Test package is to seal the capsule of mouth, to be up to the standards, and packing becomes the operation of formal product.

Six, quality standard:

1, physical and chemical index:

Hide Cordyceps extract g/100g 9.3

Tibet sheep placental extract dish g/100g 9.2

Stigma Croci extract g/100g 3

Hide wolfberry fruit extract g/100g 12.5

Hide Lac regis apis extract g/100g 9

Hide Rhizoma Polygonati extract g/120g 10.5

Tibet Fructus Hippophae extract g/100g 12

Hide Radix Astragali extract g/100g 10

Sargassum extract g/100g 14

SEMEN COICIS extract g/100g 12

Lycopene g/100g 0.33

2, instructions of taking: every day three times, each 0.7-1 gram, one after each meal.

The specific embodiment:

Embodiment: get and hide 3 kilograms of Cordyceps extracts,, 4 kilograms of Tibet sheep placental extract, 1 kilogram of Stigma Croci extract, hide 4 kilograms of wolfberry fruit extracts, hide 3 kilograms of Lac regis apis extracts, hide 3.5 kilograms of Rhizoma Polygonati extracts, 4 kilograms of Tibet Fructus Hippophae extracts, hide raw materials mixing such as 4 kilograms of Radix Astragali extracts, 5 kilograms of Sargassum extracts, 4 kilograms of SEMEN COICIS extracts, lycopene 10 grams, and stir, send into filling machine, raw material is filled in the capsule, capsule seals, be up to the standards, packing becomes formal product.

Claims (1)

1. Chinese caterpillar fungus compound prolongs spring beauty nourishing capsule processing technology, it is characterized by: hide 3 kilograms of Cordyceps extracts, 4 kilograms of Tibet sheep placental extract, 1 kilogram of Stigma Croci extract, hide 4 kilograms of wolfberry fruit extracts, hide 3 kilograms of Lac regis apis extracts, hide 3.5 kilograms of Rhizoma Polygonati extracts, hide 4 kilograms of Radix Astragali extracts, 4 kilograms of Tibet Fructus Hippophae extracts, 5 kilograms of Sargassum extracts, 4 kilograms of SEMEN COICIS extracts, lycopene 10 gram allotments mix, stir, capsule filling, capsule are sealed, test package becomes formal product.