CN101284096A - Sheep placenta capsule compound nest-defence capsule for beautifying face - Google Patents

Sheep placenta capsule compound nest-defence capsule for beautifying face Download PDF

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CN101284096A
CN101284096A CNA2008100999072A CN200810099907A CN101284096A CN 101284096 A CN101284096 A CN 101284096A CN A2008100999072 A CNA2008100999072 A CN A2008100999072A CN 200810099907 A CN200810099907 A CN 200810099907A CN 101284096 A CN101284096 A CN 101284096A
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苟春虎
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Abstract

The invention belongs to the technology field of Tibetan medical health food, particularly a hard capsule prepared from saffron extract, Tibetan medlar extract, Tibetan solomonseal extract, Tibetan angelica extract, Chinese yam extract, multiflower knotweed root extract, seaweed extract, proanthocyanidin , vitamin B6, vitamin E, vitamin C, etc. The prepration process for the hard capsule includes mixing the materials, stirring; filling into capsules, sealing; checking; and packaging to obtain finished product. The capsule is effective in caring ovary, caring skin, postponing aging, etc.

Description

Sheep placenta capsule compound nest-defence capsule for beautifying face
One, technical field:
The invention belongs to the Tibetan medicine health food, relate in particular to Tibet sheep placental extract, Stigma Croci extract, hide wolfberry fruit extract, hide Rhizoma Polygonati extract, ZANGDANGGUI extract, Rhizoma Dioscoreae extract, Radix Polygoni Multiflori extract, Sargassum extract, procyanidin, vitamin V C, vitamin V 1, vitamin V B6The health food that processes Deng raw material.
Two, background technology:
The health food that this invention is made with raw materials such as Tibet sheep placental extract, Stigma Croci extract, Tibetan wolfberry fruit extract, Tibetan Rhizoma Polygonati extract, ZANGDANGGUI extract, Radix Polygoni Multiflori extract, Rhizoma Dioscoreae extract, Sargassum extract, procyanidin, vitamin Vs.This product has effects such as care ovary, skin maintenance, slow down aging.Existing market also not this product occur, develop this product and can be the modern times Ms that likes to be beautiful a kind of novel healthy food is provided.The hard capsule that this product is made for pure natural medicine food raw material, without any side effects, free from extraneous odour, taking convenience.
Three, summary of the invention:
For the women, beautiful skin, plentiful breast, moving curve, eternal youth are the dreams that woman's serious hope has everywhere in the world been asked.Along with China's economy constantly develops, the improving constantly of national economy income and living standard, people are stronger day by day to healthy and beautiful pursuit.Especially crossed the women of adolescence and child-bearing period, loss along with the years, the ashamed decline of pursuing owing to ovarian function, variation has taken place in the organism endocrine balance, estrogen secretion reduces, it is dry coarse that skin slowly becomes, follow the string, symptoms such as mottle, pigmented spots occur, beautiful elegance loses one's bloom.Ovary is one of important histoorgan of female pathology, in case the ovary aging will cause the partes corporis humani position old and feeble fast.Because social development is accelerated, female life pressure increases, irregular, the many reasons such as stay up late of live, the ovary aging phenomenon mostly is and shifts to an earlier date, some women 30 shortly past, the senilism ill symptoms just appears.Therefore, in body, delay ovary aging and atrophy ahead of time, can make healthy and beautiful, the perpetual youth of people.
Four, composition of raw materials: Tibet sheep placental extract 4-6 kilogram, Stigma Croci extract 1-3 kilogram, Tibetan wolfberry fruit extract 10-15 kilogram, Tibetan Rhizoma Polygonati extract 10-12 kilogram, ZANGDANGGUI extract 12-15 kilogram, Rhizoma Dioscoreae extract 3-5 kilogram, Radix Polygoni Multiflori extract 8-10 kilogram, Sargassum extract 12-15 kilogram, procyanidin 1-3 kilogram, retinol1 gram-2 gram vitamin E100-150 gram, vitamin c 1-2 kilogram, vitamin BThe 80-100 gram.
Five, technical scheme:
(1) Tibet sheep placental extract (sheep ' s), (Placenta caprae seu ovis extract).Be conceived 3-5 month sheep embryo of tibetan sheep, utilize biotechnology to extract biological activity.China's tradition Chinese medicine is to animal Placenta Hominis application history for a long time.According to the record of herbal ridge order, warm in nature, the sweet-salty of sheep placental extract.Effect with the kidney invigorating, replenishing essence, benefiting qi and nourishing blood.The clinical men and women's of being used for asthenia, neurasthenia, QI and blood deficiency, spiritlessness and weakness, prolonged illness loss, spontaneous sweating, sexual disorder and endocrine disturbance are caused a disease all effective in cure.Modern medicine study, sheep placental extract is a kind of polypeptide protein material or perhaps the living cells thing that extracts from conceived Placenta caprae seu ovis, but this material activating human body skin and trachea function, effectively promote body metabolism, enhancing human body immunity power, promote human tissue cell's division, cell activity enhancing, the regeneration of reinforcement Skin Cell energy side, speckle dispelling, wrinkle-chasing, enhancing skin elasticity and gloss, delay youth, skin whitening, defying age, relieving mental strain and helping sleep, improve memory, allaying tiredness etc.
Chemical analysis: contain DNA (deoxyribonucleic acid) and nucleic acid, polypeptide protein, ten several amino acids, mucopolysaccharide, lecithin, vitamin B group etc.
Pharmacological action: 1, antioxidation: sheep placental extract was to 20 months healthy geriatric rat 150mg/kg every day body weight, 300mg/kg, 600mg/kg per os award sheep placental extract solution, after 80 days, measure respectively and respectively organize superoxide dismutase (SOD), malonaldehyde (MDA), monoamine oxidase, MAO (MAO) in rat erythrocyte and the tissue.The sheep placental extract SOD content in the old rats erythrocyte that can obviously raise reduces MAD content in serum and the hepatic tissue, and reduces cerebral tissue MAO vigor, so sheep placental extract has antioxidation to old rats as a result.
It is reported that the foreign study experiment shows that (1) fruit bat average life increases by 17.7%, human body is taken 15 days experimenter's lipid peroxides and is descended, and superoxide dismutase (SOD) value rises, and illustrating has positive effect to human body MDA (malonaldehyde), SOD.(2) rat blood serum and liver MDA descend 15%, and lipid oxide is had inhibitory action.(3) rat blood serum SOD raises 9.63%, and the manganese antioxidase raises 33.13%.
2, defying age: sheep placental extract has irritation cell regeneration capacity, slow down aging.It is reported that embryonic stem cell that sheep placental extract and umbilical cord contain and adult stem cell, these active component have face nourishing antidebilitation and act on always.
3, enhancing immunity; Studies show that, sheep placental extract compares mice nonspecific immunity and specific immune function index analysis, the phagocytic function of the thymus of sheep placental extract high dose group, low dose group, index and spleen index and mononuclear phagocyte all obviously improves, the conversion reaction of splenocyte strengthens, serum hemolysin generation value also increases, so think that sheep placental extract has the effect that improves the mice body's immunity.
4, endocrine regulation: sheep placental extract has obvious effects to regulating the hormone secretion function, can improve human body hormone secretion level, the aging of delaying female ovary, changes the ovary function, prevents climacteric obstacle, physiological change.
5, looks improving and the skin nourishing: studies show that, contain a series of micromolecule polypeptides such as peculiar superpower biological activity SF and BF in the sheep placental extract, its relative molecular weight is 3800-5000, it can activate Skin Cell regeneration, make it to breed degree of progress speed, activation skin surface tissue, removing also stops harmful oxide to be accumulated and melanocyte formation melanosome, mottle can't be formed, keep skin-whitening, promote the elastin laminin cell proliferation, make the skin reticular fiber structure become closely flexible, keep moisture of skin to be difficult for running off and replenish skin-nourishing comprehensively, the balance skin metabolism is eliminated pachylosis, dry and cracked phenomenon makes skin become tender and lovely.Therefore sheep placental extract has just enjoyed the women to welcome since coming out.
6, smooth away wrinkles: sheep placental extract can promote the elastin laminin cell proliferation, makes the skin reticular fiber structure become closely flexible, makes moisture be difficult for running off, and replenishes skin-nourishing comprehensively.According to another report, the loose corrugated reason of the skin influence that is free radical.Sheep placental extract has the effect of oxidation and removing free radicals, can dispel facial wrinkles.
7, promote hemopoietic, improve anemia: research thinks, sheep placental extract can hemopoietic tissue, promotion hemopoietic has tangible anti-anemia effect, the effect of rising erythrocyte significantly promotes the bone marrow hematogenesis function, improves the asthenia universalis symptom.
In addition, sheep placental extract also has the absorption that improves sleep, promotion human body metabolism, adjusting sympathetic nerve, strengthens protein and other nutritional labeling.
(2) Stigma Croci extract (Stigma croci) (Stigma Croci, Stigma Croci), the perennial perennial root herbaceous plant of Iridaceae safranine Pittosporum, croceous dried floral stigma.Sweet, the mildly bitter flavor of property.The traditional Chinese medical science think have blood circulation promoting and blood stasis dispelling, blood-cleaning detoxifying, the resolving stagnation for tranquilization effect.Have analgesia, diaphoresis stimulate the menstrual flow, dispel the wind cold, be good for the stomach, alleviate effects such as climacteric.Stigma Croci is a rare Chinese medicine simply, has unique effect aspect nourishing blood and promoting blood circulation.According to Compendium of Material Medica record, Stigma Croci can " invigorate blood circulation, main motive melancholy, smelting palpitation with fear again." use Stigma Croci clinically and dredge effects such as channels and activating collaterals, the blood stasis dispelling of stimulating the menstrual flow, dissipating blood stasis relieving accumulation of pathogens, reducing swelling and alleviating pain, removing pathogenic heat from blood and toxic substance from the body, troubled thoughts pent-up.Be widely used in diseases such as anemia body void, menoxenia, postnatal blood stasis, general aching, traumatic injury, neurasthenia, palpitation with fear is demented by China and foreign countries' medical circle.Other has report, and Stigma Croci is very famous and precious simply Chinese crude drug, has and nourishes blood, invigorate blood circulation, and removing heat from blood, effects such as regulating menstruation by adjusting the flow of blood, be undivided with blood woman's all one's life, and energy and blood of human body is full, and the ability hair is deceived profit, skin is glossy.
Chemical constituent: main component carotenoid is main pigment of Stigma Croci and active ingredient.Comprise the Stigma Croci aglycon, saffron glucoside and Stigma Croci mono-methyl, Stigma Croci dimethyl ester etc.It after the Picrocrocin hydrolysis volatile safranal.Volatile oil, diphenyl ethanol etc.
Pharmacological action: 1, antioxidation: the Stigma Croci extract has removing and inhibitory action to oxygen-derived free radicals.
2, health invigorating: under long-term work and pressure, modern female body constitution relatively a little less than, very easily be subjected to virus evil to cause various diseases and gynecological inflammation.And Stigma Croci can strengthen the immunologic function of cell, promotes the huge function of biting, and around the scavenger cell " rubbish ", thereby plays self-resistance, away from the effect of viral disease invasion.
3, regulation of mental activities pneumostatic: work long hours and life stress, make the woman feel the mood unhappiness, discharge nowhere, particularly there is the anxiety sense in climacteric women regular meeting, feels to upset, and symptoms such as tired, hypopnea are arranged, so that temper becomes quick-fried dry.Stigma Croci energy endocrine regulation is removed the mottle that causes because of the endocrine disturbance, and can in time promote the blood of human body circulation, the supply of blood oxygen, thus make women's QI and blood smooth and easy, keep good physical and mental statuse.
4, the skin Caring that nourishes blood: modern female gathers quickening because of work and life joint, causes symptoms such as anxious, sleep quality reduction easily, be reflected in the face skin anoxia, lose natural gloss, can occur when serious that the blood stasis of blood stagnates, pigmentation, chloasma, mottle etc. occur.Stigma Croci can be brought into play its anti-skin anoxia function of invigorating blood circulation to greatest extent, and obviously blood circulation promoting allows skin obtain competent blood oxygen, moisture and nutrition, makes skin dynamic, and fine and smooth moist, confidence gradually recovers one's health.
5, blood fat reducing: the Stigma Croci total glycosides can obviously suppress the rising of Carnis Coturnicis japonicae by serum TC, TG, LDL-C, VLDL-C and AI due to the hyperlipidemia diet, can alleviate tremulous pulse due to the hyperlipidemia feedstuff, the formation of atherosclerotic plaque, but Stigma Croci aglycon cholesterol reducing promote lipid metabolism.
6, suppress tumor: Stigma Croci 100-200mg/kg mouse gavaging is to S 180, ehrlich carcinoma, MCA sarcoma all have the inhibition effect, its effective ingredient is Stigma Croci aglycon (crocetin)
Also have in addition, promoting blood circulation and hemostasis, removing pathogenic heat from blood and toxic substance from the body, promote the arteria retina blood flow, functions such as resisting fatigue, relieving constipation.
(3), hide Fructus Lycii (Lycium barbarnm extraat), Fructus Lycii is the sub-mature fruit of matrimony vine of solanaceae plant.The property flat, sweet in the mouth.Have by Liver and kidney, promoting generation of vital essence and blood makes eye bright, lung moistening, beauty treatment, functions such as fat-reducing.
Chemical constituent: the Fructus Lycii main component has polysaccharide, aminoacid, Folium hydrangeae strigosae alkali, carotene, vitamin B1, vitamin B2, various trace elements such as multivitamin such as vitamin C, nicotinic acid and manganese, chromium, zinc, copper, magnesium, calcium, germanium, cobalt, ferrum.
Pharmacological action: 1, protection birth-death system, it is reported that achievement in research of HSPH of Wuhan University shows, lycium barbarum polysaccharide can produce protective effect to the reproductive system that is damaged by effect " hypothalamic-pituitary-gonadal " this axis.
Experiment shows that lycium barbarum polysaccharide promotes hypophysis secreted glandular hormone by the gonadotropin effect, and " hypothalamic-pituitary-gonadal " this axis is produced the multilamellar regulating action, impels the spermatogenesis process unimpeded normal with testis sexual cell growth.
2, sexual function improving: Fructus Lycii has invigorating the liver and kidney, promoting generation of vital essence and blood, supporing yang function.No matter be that insufficiency of kidney-YANG, deficiency of the kidney yin all have certain effect, Fructus Lycii extract also has the effect of short gonad function, and plasma testosterone level is significantly raise, and property kinetic energy is gone down, and sexual impotence plays an important role.
3, enhancing immunity: Fructus Lycii is a medicine-food two-purpose food, and the Fructus Lycii polysaccharide has enhancing immunity, and antitumor action can strengthen the cell anti-cancer function selectively.Lycium barbarum polysaccharide can strengthen natural killer cell and lymphocyte vigor, promotes interleukin to generate, and strengthens monocytic immune vigor.The Fructus Lycii polysaccharide also has antimutagenic effect, when mutation produces genetic damage and cell mutation, can repair damaged cell and recover its normal function.
4, defying age: Fructus Lycii has the rejuvenation effect, and showing as to stimulate gonad and endocrine, strengthens hormonal secretion, strengthens the physiological function of brain function and neurocyte.The toxin phenomenon occurs accumulating in the blood though can avoid people's age growth, thereby keep the normal function of in-vivo tissue.But Fructus Lycii polysaccharide antagonism free radical peroxidase activity strengthens superoxide dismutase and glutathione peroxidase vigor, thereby the damage that alleviates the radical pair body has the effect of defying age.
5, the clay thing of a kind of indomitable vitality of Fructus Lycii, the traditional Chinese medical science think that taking Fructus Lycii can help human body to strengthen energy, nourishing the liver and kidney, replenishing vital essence to improve eyesight, the increase immunity that nourishes blood, and the effect that Fructus Lycii adapts to most is exactly a resisting fatigue.Resisting fatigue: Fructus Lycii can be improved hydroxyproline concentration, thereby improves muscular strength, and fatigue capability is strengthened.
Six, the liver protecting: Fructus Lycii extract has certain effect to hepatoprotective and fatty liver.Reason is that Fructus Lycii contains a kind of effective ingredient one Folium hydrangeae strigosae alkali, and it is effective to the treatment liver.Pharmacological research shows that Folium hydrangeae strigosae alkali has the fat of inhibition to deposit, and promotes the effect of liver cell regeneration in hepatocyte.Concerning the liver patient, the Folium hydrangeae strigosae alkali in the Fructus Lycii can prevent that fattiness stores in the liver, and lipotropic effect is arranged, and contained chlorophyll helps the liver detoxification effect in the Fructus Lycii, can also increase and improve liver function simultaneously.Chronic hepatitis patients, especially fatty liver patient.
7, blood fat reducing: Fructus Lycii extract can reduce the rat cholesterol, and the cholesterol that can obviously suppress hypercholesterolemia and the caused rabbit anteserum of Adeps Sus domestica feedstuff increases.
8, blood sugar lowering: wolfberry fruit extract can reduce rat blood sugar significantly enduringly, improves carbohydrate tolerance.
9, control age-related macular degeneration: Fructus Lycii has the soothing liver-QI effect that makes eye bright.To chronic hepatitis, central serous chorioretinopathy, optic atrophys etc. are evident in efficacy.Ageing disorders such as old organ senescence had very strong improvement effect.Discover that Fructus Lycii helps to reduce the generation of old degeneration maculopathy.
10, anti-apoptotic: apoptosis is called programmed cell death again.Interrelated data shows that brain normally has 10 nerve cell deaths every day approximately, and the human body neural thin breast of tissue regeneration promoting more not.When the fast a large amount of apoptosis of thin breast, senilism, weak, film attenuation and atrophy can appear in the people, skin thousand wrinkles, and with a haggard face, memory and ability of thinking descend, even it is slow-witted old disease to occur.
Apoptosis except with occur outside the Pass pathology and inherited genetic factors have, a large amount of apoptosis fast and two factors are closely-related; First free radical is made the oxidation reaction of use free radical with old and feeble closely related, causes that the free radical of cellular oxidation all can cause apoptosis.Studies confirm that, the cerebroside ester that Fructus Lycii contains is that oligosaccharide combines formed glycosides with the ceramide terminal hydroxyl, owing to cerebroside ester is combined into by hydrophilic glycosyl and lipophilic ceramide, be one of important component of cell membrane, can keep cyto-architectural integrity.Simultaneously, cerebroside ester can form hydrogen bond network widely in biomembrane polarity and nonpolar interface.This is to constitute the constitutionally stable key factor of biomembrane stratiform.
According to another report, Ca2+ extensively raises in the inductive thymocyte cell of LBP DEX capable of blocking, suppresses the inductive dna segmentization of DEX, and inhibitory action has dose dependent, its mechanism of action may pass through to reduce the wide concentration of cell C for LBP, suppresses the endonuclease enzyme activation, thus the blocking-up apoptosis.
11, antitumor: the lycium barbarum polysaccharide combination with radiotherapeutic has certain radiosensitizing effect to acute weary oxygen tumor cell.Lycium barbarum polysaccharide has in non-specific antitumor and the specificity antineoplastic process macrophage certain activation is all arranged.With S180 lotus tumor Bal6/C mice is model, discover, mice with tumor spleens cell number and activating T cell multiplication capacity can be recovered and improve to lycium barbarum polysaccharide, promotes the active and TNF secretion level of NK, and the prompting lycium barbarum polysaccharide can strengthen cellular immune function makes it suppress the dominant mechanism of tumor effect.
12, beauty treatment is preserved youthful looks: deposit in hepatocyte so defying age can suppress lipid, promote hepatocyte new life's effect.Fructus Lycii contains carotin, and compositions such as thiamine, riboflavin, Yan acid have moist skin, and the color of preserving youthful looks is the good merchantable brand of beauty treatment.Fructus Lycii can improve the ability to take oxygen of skin, can play the effect of skin whitening.
It is reported that Britain, French medical science man discover that Fructus Lycii contains a kind of vitamin of not meeting, and is named as " vitamin ", is also referred to as the vitamin of preserving youthful looks.So Fructus Lycii extract has extremely strong skin maintenance effect.
(4) hide Rhizoma Polygonati: (Huang jing), for my year living Liliaceae is planted the dry rhizome of taxi.Property is done, sweet in the mouth, is returned spleen, lung, kidney strong.Effect with spleen reinforcing yin nourishing, spleen invigorating lung moistening, the kidney invigorating.Be used for that weakness of the spleen and stomach, body void are weak, mouthfeel lack of appetite, the dry larynx of the deficiency of the lung.Be longer than invigorating the spleen and replenishing QI, the foster taste of benefit, sick body void, weakness of the spleen and stomach, xerostomia lack of appetite, asthenia of essence and blood.The Compendium of Material Medica record: the Rhizoma Polygonati QI invigorating is transferred smart, gentle, the muscle sufficiency of the five internal organs.Have not old for many years, the blackening of turning white, dedentition and give birth to effect.Modern pharmacological research, Rhizoma Polygonati effectively blood pressure lowering and blood glucose can increase the symptom blood flow volume completely, play blood fat reducing and delay arteriosclerotic effect.
Chemical constituent: mainly contain polygonatum polysaccharide class, steroid saponin, flavone, several amino acids, alkaloid, mannitol, lymphatic temperament, flower quinones etc.
Pharmacological action: 1, improve immunity: discover that Rhizoma Polygonati has the effect that strengthens the human T cell.Immune function of human body be can strengthen, DNA, RNA and proteinic synthetic promoted.Lymphocyte transformation to the immunologic hypofunction patient has excitation.Compound recipe can make mice breast arteries and veins weight show to be increased, and can improve the humoral immunity level of thin breast sum of animal spleen T and external source thymus-dependent antigen, strengthens cellular immune function.Mice is wrongly taken coarse solomon's seal polysaccharide 400mg/kg, can obviously strengthen thymus and spleen weight after 7 days, obviously strengthens wind shape endothelium and does not unite to the phagocytic activity of india ink.
2, antioxidation: Rhizoma Polygonati can improve the free radical ability.The Rhizoma Polygonati decoct can obviously improve the content that superoxide dismutase activity in mouse red blood cell and the liver reduces cured brown matter in mouse cardiac muscle and the cerebral tissue.The Rhizoma Polygonati oral liquid can significantly reduce the heart, liver lipid oxidation thing (LPO) generates, and increases superoxide dismutase, and the paddy Guang is peptide peroxidase (GSH-P) vigor and the super oxidation synthase of blood vigor.Show that Rhizoma Polygonati can obviously improve body free radical resisting ability, to suppressing the effect that LPO generates the tool uniqueness.Coarse solomon's seal polysaccharide can reduce mda content in the carbon tetrachloride poisoning murine liver tissue, has anti-matter and refers to peroxidation.
3, defying age: wrongly took decoct 27 days to mice, can obviously reduce myocardium lipofuscin content and improve the liver SOD activity, the lipid peroxidation that the protection free radical causes has anti-aging effects to the infringement that biofilm structure and function cause.Wrongly take Rhizoma Polygonati 6g/kg to mice, the activity of 10 days erythrocyte Na+ that can raise, K+-ATP enzyme.Polygonatum polysaccharide promotes mouse lymphocyte conversion ratio, erythrocyte, crystal nuclear, lens cortex superoxide dismutase SOD activity.Water decoction 2.59g/kgd, 3g/kgd can make skin hydroxyl dried meat amino acid content increase by 6.6% in 1 month for the mice gastric lavage, significantly improved lactic acid dehydrogenase activity and brain homogenate catalase activity in cardiac muscle and the cerebral tissue, can obviously improve the mice hypoxia-bearing capability.The telomerase activation of old and feeble rat brain, the gonadal tissue of can significantly raising.
4, antipathogen: experiment in vitro shows that the Rhizoma Polygonati water decoction is to Bacillus typhi, and golden yellow or the like coccus, acid-fast bacilli and adenovirus and cancer virus have inhibitory action.Tuberculosis is had notable therapeutic effect, and curative effect is carried nearly isoniazid.In addition multiple fungus also there is inhibitory action.
5, improve adrenal cortex function: Rhizoma Polygonati has the effect that suppresses adrenal cortex function, and caused fat, neat random the having some improvement of carbohydrate metabolism are advanced by adrenal cortex unit.
6, the liver protecting: coarse solomon's seal polysaccharide can obviously reduce the mda content in the CCI4 poisoning mice hepatic tissue, has lipoid peroxidization resistant.
7, resisting fatigue: the Rhizoma Polygonati water decoction is wrongly taken mice and is carried out the swimming test result and show, mice prolongs at the frozen water swimming time, can strong mice muscle power and to stressed condition down opposing can, have remarkable antifatigue effect, it is relevant that the many low thighs of this effect cause kinases (CK).Rhizoma Polygonati also has good anti-tubercle bacillus to do in addition, thereby is fabulous tonification anti-fatigue product.
8, anti-hypoxia: experiment shows, the Rhizoma Polygonati water decoction is wrongly taken and can be improved mice and survive under anoxia condition and utilize ability, to increase often anti-sound when scarce.Significantly improve lactic acid dehydrogenase activity and brain homogenate catalase activity in cardiac muscle and the cerebral tissue, can obviously improve the mice hypoxia-bearing capability.
9, radioprotective: polygonatum polysaccharide can obviously resist the minimizing of 6 ℃ of gamma ray induced mice peripheral leukocytes and total number of blood platelet, can obviously improve irradiation mice peripheral red blood cells C3b receptor rosette rate and immune complex rosette rate.
10, coronary artery dilating, anti-scheming ischemia: experiment showed, that Rhizoma Polygonati can make rat heart thigh contractility obviously strengthen, the coronary disease mistake flow that exsomatizes is obviously increased.Intravenous injection have the antagonism pituitrin due to the effect of acute heart thigh ischemia.
11, anti-leukopenia: polygonatum polysaccharide can the cruel amine of bright antagonism ring phosphorus institute reduce to locating the mice peripheral blood leucocyte, the mouse spleen weight of immunocompromised is increased, its leukogenic effect may be the hypertrophy by the spleen Interstitial cell, and performance compensatory marrow is made its function outward.
12, blood fat reducing: exempt to take 100% decoct 10ml/d to hyperlipidemia, 30 days, can obviously reduce trigalloyl oil-beta lipoprotein, cholesterol (TC), alleviate aorta wall speckle and crown arteriosclerosis.Exempt to take polygonatum polysaccharide 1.6ml/gkd to hyperlipemia, can obviously reduce serum LDL-C, LP (a), TC concentration and minimizing, the aortic tunica intima foam cell forms.
13, blood sugar lowering: polygonatum polysaccharide 500/kg, can significantly reduce epinephrine, model mice blood glucose and liver CAMP content.Extractum and methanolic extract can suppress the glycogen alcoholysis, to adrenal gland, chain urea toxin bring out blood sugar increasing mice, exempt from that the obvious functions of blood sugar effect is all arranged.
14, tuberculosis: water decoction is external to have the obvious suppression effect to tubercule bacillus.
(5) ZANGDANGGUI (Amgelica) is when the loose root that is classified as the perennial herb samphire.Warm in nature, sweet in the mouth puts down, has that blood circulation promoting and enriching, regulating menstruation are moisturized, the function of intestine moistening.Functions such as brain-strengthening, the liver protecting, constipation.
Chemical constituent: mainly contain volatile oil, linoleic acid, nicotinic acid, vitamin B 12, polysaccharide, β-paddy stay compositions such as alcohol.
Pharmacological action: 1, enhancing immunity: Radix Angelicae Sinensis and Radix Angelicae Sinensis polysaccharide (AIP) are to non-specific immunity, cellular immune function, and humoral immune reaction and cytokine all have significant facilitation.The body that immunologic function is in inhibitory state also has adjusting and restitution.
2, improve anemia: Radix Angelicae Sinensis aqueous extract, Radix Angelicae Sinensis polysaccharide all can significantly promote the generation of hemoglobin, erythrocyte, leukocyte and bone marrow nucleus.This act on that peripheral blood cells reduces and bone marrow particularly evident when being suppressed.As giving the mice abdomen injection stupid hydrazine of Radix Angelicae Sinensis polysaccharide or 60 ℃ of irradiations in advance, the recovery of mice hemopoietic function all there is significant facilitation.Chinese angelica oral liquid has tangible anti-anemia effect, and In vitro culture also proves that Radix Angelicae Sinensis polysaccharide has the anemia mice of stimulation granulocyte, the effect of monosystem CFU-GM (CFU-GM) propagation.
3, the liver protecting: toxic hepatitis has protective effect to the Radix Angelicae Sinensis water decoction to chmice acute CCL4.And prevent that hepatic glycogen from reducing; With the Chinese Angelica Root forage feed mice that contains 5% the liver oxygen consumption is increased, it is stable that hepatic glycogen keeps.According to another report, the ferulic acid that contains of Radix Angelicae Sinensis has protective effect to hepatic injury.Experiment shows that the sodium ferulate steel is the antagonism bromobenzene effectively, acetaminophen, and number of chemical liver damages such as ethanol, and to hepatic ischemia, reperfusion injury and immunologic liver injury have protective effect.
4, beauty treatment: Radix Angelicae Sinensis contains a large amount of volatile oil, vitamin, organic acid and trace element, waits multiple organic component, and experimentation shows that Radix Angelicae Sinensis can be expanded peripheral blood vessel, reduces vascular resistance, increases blood circulation amount etc.Can suppress melanin and form, to treat yellowish-brown class, freckle isochrome disposition dermatosis has good effect.Someone adds Radix Angelicae Sinensis in cosmetic cream, the class's of the dispelling frost to, to ask for skin nutrition, prevents the yellowish-brown class of acne, effects such as freckle.Without any side effects through observing.Radix Angelicae Sinensis can promote natural on-off cycles of hair growth, and the hair conditioner elder generation hair cream with Radix Angelicae Sinensis is made can make hair soft shinny, is easy to combing.
5, prevent and treat gynaecopathia: from China Northern and Southern Dynasties, Radix Angelicae Sinensis is regarded as the treasure of invigorating blood circulation of enriching blood, its energy tonifying blood and regulating menstruation, promoting blood circulation and stopping pain, damp face skin moistening, and the strong body life lengthening of granulation promoting is being played the part of extremely important role in the protection women's health.Li Shizhen (1518-1593 A.D.) thinks that Radix Angelicae Sinensis is the good medicine that the woman transfers blood.
(6) Rhizoma Dioscoreae (Chinese Tam) has another name called Rhizoma Dioscoreae.Dry rhizome for Dioscoreaceae plant Rhizoma Dioscoreae.The property flat, sweet in the mouth, be spleen, lung, kidney channel.Have the spleen reinforcing nourishing the stomach, effect such as the lung benefiting that promotes the production of body fluid, supplementing QI and nourishing YIN, the kidney invigorating arresting seminal emission, deficiency of kidney-YIN.Modern medicine thinks to have antioxidation, and functions such as nest breast enlargement, blood lipid regulation are protected in defying age, enhancing immunity function, blood sugar lowering, skin maintenance.
Chemical analysis: contain Rhizoma Dioscoreae element, Chinese yam polysaccharide, sterols, dioscin, diosgenin, choline, several amino acids, calcium, ferrum, vitamin C, dietary fiber etc.
Pharmacological action: 1, regulate immunologic function: Chinese yam polysaccharide can promote that the lymphocytic hypertrophy of T and natural killer cell are to the toxic action of lymphocytic cancer cell in the spleen.Can increase mouse spleen weight, increase the immunosuppressive action of clear effect in carbon granules corridor and anti-cyclophosphamide,, stronger facilitation be arranged mouse cell immunity and humoral immunization.
2, antioxidation: Chinese yam polysaccharide can reduce the microsome lipid peroxide content that Vc-dihydrocoenzyme II and Fe2+-cysteine bring out, and the lipid peroxidation of the hydroxy radical cell membrane that produces of the superoxide radical that xanthine-xanthine oxidase system is produced and reaction system.According to Taiwan, Rhizoma Dioscoreae all has certain oxidation resistance because of being rich in polyphenols.Immunity is awarded high cholesterol diet, compare with matched group, Rhizoma Dioscoreae can obviously reduce T-CHOL in the blood, triglyceride LDL, and free-radical contents and arteriosclerosis plaque, the activity of antioxidases such as increase SOD has good removing ability to the DPPH free radical.
3, defying age: feed silkworm significant prolongation silkworm length of time but studies show that 20% Rhizoma Dioscoreae decoct soaks to dry in the shade behind the Folium Mori, and silkworm height, body weight increase slowly than matched group, food Mulberry amount also reduces.Can prolong the effect in silkworm children's phase and whole life-span.
4, endocrine regulation: the dioscin of Rhizoma Dioscoreae can change into dehydroepiandrosterone (DHEA) through the part of the diosgenin after the hydrolysis in intestinal, DHEA is rich in the adrenal gland, is the body inner estrogen, endocrine precursor substance such as testosterone.Known KHEA reduces with advancing age and gradually, and is relevant with many catabiosis.Experiment confirm awards Rhizoma Dioscoreae 390 grams every day to postmenopausal women, and after 30 days, estrogen, DHEA and sex hormone binding globulin all to some extent obviously increase.
5, breast enlargement: Rhizoma Dioscoreae extract energy endocrine regulation promotes women's gland and the development of ovary, especially breast.Discover, to having crossed the women of adolescence and child-bearing period, along with the loss in years, ovarian function is slowly old and feeble, and estrogen secretion reduces, and breast atrophy gradually is sagging, Rhizoma Dioscoreae extract can increase the female gonad cytoactive, stimulates breast, makes breast become tall and straight plentiful.
6, blood lipid regulation: give mice, rats gavaged and injection diosgenin, hyperlipidemia is had tangible prevention and therapeutical effect.The external effect that has obvious inhibition cholesterol microparticle to form.
7, blood sugar lowering: contain abundant resistant starch (27.3%) in the Rhizoma Dioscoreae, can prevent the common starch hydrolysis, delay the hydrolysis rate in digestion, thereby slow down blood sugar effect.Once injected 10-100mg/kg to normal mouse with by the hyperglycemia mouse peritoneal of model induced by alloxan, the blood sugar lowering rate is 39%-43% after 7 days, after 24 days 52%-72%, the plasma glucose of test group, lactic acid and fructose ammonia (a kind of glycated proteins can be used as the index of long-term assessment blood sugar concentration) all are lower than matched group.
8, antitumor: Chinese yam polysaccharide has very strong anti-tumor activity to mice transplantability melanoma.
9, anoxia enduring: experimental result shows that Rhizoma Dioscoreae energy significant prolongation mice has extremely significant normobaric hypoxia effect in the time-to-live of anaerobic condition.
(7) Radix Polygoni Multiflori (Tuber fleecefiower) is the Polygonaceae tuber of light voluble herb plant Radix Polygoni Multiflori for many years.Warm in nature, sweet-puckery flavor have black beard and hair, bone and muscle strengthening, and the traditional Chinese medical science thinks that Radix Polygoni Multiflori has invigorating the liver and kidney, benefiting essence-blood function.Be used for hepatic and renal YIN deficiency insufficiency of blood, dizzy insomnia, soreness of the waist and knees, skin care, early whitening of hair bleeding not during menses, hyperlipidemia, effects such as loosening bowel to relieve constipation.
Chemical constituent: mainly contain chrysophanol and chrysophanic acid, rheum-emodin, rheum-emodin methyl ether stilbene glucoside, lecithin matter enrich various trace elements such as ferrum.
Pharmacological action: 1, slow down aging: Radix Polygoni Multiflori extract can promote cell division and propagation, the passage number of prolong rats and fruit bat diploid fibroblast.Can increase mouse brain, the content of monoamine neurotransmitters such as liver protein content and cerebral tissue 5-hydroxy tryptamine prolongs the active decline of SOD in old rats and mouse core, liver, the brain blood.Water decoction is irritated stomach to Aged Mice, SOD content is descended ease up or increases, can bright inhibition brain, monoamine oxidase-B (MAO-B) in the liver, and its effect belongs to first of Chinese herbal medicine.Can also make the unlikely atrophy of Aged Mice thymus, even keep young level.Radix Polygoni Multiflori can strengthening bone and muscle in addition, long marrow, the gas of enriching blood, life lengthening.It is cured that Radix Polygoni Multiflori contains abundant ovum phosphorus, and lecithin is to constitute nervous tissue, particularly encephalomyelic important substance.Having defying age does.
2, enhancing immunity: Radix Polygoni Multiflori extract can improve huge thin phagocytic function, the enhancing non-specific immunity ability, and energy enhancing body T cell and bone-marrow-derived lymphocyte function of biting of mouse peritoneal.With enhancing specific immunity ability, but to increase the T lymphocyte.
3, the liver protecting: the Radix Polygoni Multiflori decoct can resist rat fat liver and hepatic injury for rats gavaged, suppresses the rising of liver lipid peroxide, effects such as protection and stable liver plasma membrane.
4, improve anemia: Radix Polygoni Multiflori is rich in compositions such as ferrum and ovum phosphorus film, can promote hemocyte new life and grow, and water extract can improve the propagation of inmature group cell and hematopoietic stem cell, makes reticulocyte ratio rising in the peripheral blood.The reinforcement hemopoietic function of bone marrow is arranged, promote effects such as erythrocyte generation.
5, looks improving and the skin nourishing: the main component of Radix Polygoni Multiflori is chrysophanol, chrysophanic acid, rheum-emodin, lecithin etc.Effect is that the liver and the kidney tonifying, fitness are prolonged life, often join other medicine use the people is had rosy cheeks, hair is pitch-black, the replenishing QI and blood of ancients' meaning, black beard and hair improving healthy complexion, for a long time clothes grow muscles and bones, beneficial marrow, prolong life not old.
6, falling blood refers to: Radix Polygoni Multiflori extract has the promotion enterokinesia, hyperlipidemia disease models such as rat, rabbit all there is the effect that reduces blood cholesterol, triglyceride and β one lipoprotein content, and can reduce atheromatous plaque formation, the effect of lipidosis and increase HDL-C.According to another report, Radix Polygoni Multiflori extract can reduce total plasma cholesterol, the effect of glycerol three vinegar and beta Lipoprotein, and can reduce the effect of content of triglyceride in the cholesterol level and liver in the aorta.
7, improve endocrine function: Radix Polygoni Multiflori extract can promote adrenal cortex function, increases adrenal gland's quality, makes thyroxine content increase in the blood.
8, antibiotic: the Radix Polygoni Multiflori has antagonism to staphylococcus aureus, Staphylococcus albus, shigella flexneri, Bacillus typhi.
9, protection brain nervous cell: it is reported, Xuanwu Hospital of Capital University of Medical Science pharmacology section research department, the research worker test of Beijing brain aging key lab finds that the effective ingredient stilbene glucoside of Radix Polygoni Multiflori has protective effect to cerebral neural cell injury.Result of study confirms, stilbene glycoside of radix-polygoni multiflori extract causes to β one amyloid egg fragment 25-35 and hydrogen peroxide that the cranial nerve cell survival rate descends and lactic acid dehydrogenase spills to increase tangible antagonism is arranged.The main component of stilbene glucoside as Radix Polygoni Multiflori is described, the control of nervous system degenerative diseases such as senile dementia is had good action.
(8) Sargassum extract (Sea weed) is the frond of Sargassaceae Brown algae, comprises the dwell dry body of Lay and Sargassum of sheep, has hard masses softening and resolving, expectorant diuretic function.Modern medicine study has blood fat reducing, blood sugar lowering, fat-reducing, improves looks, enriches blood, toxin expelling, protect the liver, function such as antitumor, antiviral.
Chemical analysis: mainly contain Sargassum polysaccharides: the sheep Lay Polysaccharide A of dwelling, the sheep Lay polysaccharide C of dwelling, sargassan etc.24-ethylidenecholest-5-en-3.beta.-ol., saringosterol, iodine, ferrum various trace elements, aminoacid, multiple nutrients materials such as unsaturated fatty acid.
Pharmacological action: 1, regulate immunity; Experiment shows: Sargassum polysaccharides can improve mouse boosting cell DHA synthesizing activity, and the cytophagous digestion activity of anti-staphylococcus aureus has facilitation, to cytokinesis.Discover that further Sargassum polysaccharides also has facilitation to the generation of splenocyte polyclonal antibody (IM and IgG).Sargassum polysaccharides can strengthen specific immune function and non-specific immunity, strengthens the phagocytic activity of Turnover of Mouse Peritoneal Macrophages and the function of pair cell immunity and body fluid and humoral immunization.
2, protect the liver: Algin has certain preventive and therapeutic effect to hepatic fibrosis in mice.The control of hepatic fibrosis is the treatment chronic hepatopathy, the important channel that the control liver cirrhosis forms.Its mechanism is relevant with the adjusting immunologic function with its microcirculation improvement.
3, enrich blood: Sargassum contains abundant organic iron element, and for general rich ferrum food 20 times can effectively strengthen hematopoietic function, and to severe loss of blood, low sanguinin anemia and iron deficiency anemia have significant curative effect.
4, beauty treatment: Sargassum contains a large amount of chlorophylls, vitamin A, vitamin E, vitamin B group and bioactive ingredients, to promoting skin cell metabolism, preventing athero, pigmentation and xerosis cutis, keratinization, delaying decrepitude of skin, alleviate the preceding syndrome of postmenopausal women, having taken the senile plaque of dispelling, chloasma effect for a long time, is ideal beauty treatment good medicine.
5, toxin expelling: Sargassum extract is the street cleaner of human body endogenous toxin material.Clinical trial shows, can remove human body and accumulate radiant, removes the toxic and side effects of important meals ion, virus and medicine in the human body.Suppress renal damage, its mechanism Sargassum contains the effect that abundant chlorophyll has absorbing toxin, can discharge harmful substance in the body.
6, antiviral: growth has the obvious suppression effect to red seaweed polysaccharide to bovine immunodeficiency virus, and its suppression ratio is respectively 85.96% and 88.63%.From the polysaccharide that little red algae is extracted, virus duplicating in parasitic cell can be stoped, and virus intrusion normal cell can be prevented effectively, to escherichia coli and viral infection, inhibitory action is arranged.
7, radioprotective: Sargassum polysaccharides can promote to be subjected to the recovery of radiation damage mouse hemopoietic system, strengthens the mouse anti radianting capacity, improves the activity of SOD in the mice whole blood, reduces the content of peroxide in the hepatic tissue, delays body aging.
8, antitumor: the proteoglycan (PPF) that extracts in the Sargassum is discovered ScaIettucET gonp in polysaccharide; When the content of polysaccharide was 50mg/kg, inhibition rate of tumor growth was 64.55%, and the leukocyte circulation reaches 65.11%.When the gonpi polysaccharide was 50mg/kg, life prolongation effect reached 18%-31%.Sargassum polysaccharides has strong immunoregulation effect to Turnover of Mouse Peritoneal Macrophages, may make one of its important mechanisms that suppresses tumor.The microalgae polysaccharide also has high inhibitory to S180, to the phagocytic function of mononuclear phagocyte, and the generation of mouse immune organ weight, spleen lymphocyte proliferation, the serum hemolysin effect that all is significantly improved.
9, fat-reducing: Sargassum extract was taken in preceding on the feed 30 minutes or 1 hour, but appetite-suppressing reduces appetite, made health obtain avoiding heat surplus, athero under the prerequisite of sufficient nutrition supply, reached the purpose of fat-reducing.
10, antioxidation: discover, extract low-molecular-weight fucoidan (LMSF) in the Sargassum, can directly eliminate oxygen anion free radical and hydroxy radical, SOD activity in remarkable enhancing serum and the tissue is also arranged in vivo external.
In addition, Sargassum extract also have blood fat reducing, blood sugar lowering, prevent constipation, control must angiopathy, effects such as blood pressure lowering.
(9) proanthocyanidin (GSE) is a kind of reactive compound that Semen Vitis viniferae extracts.Proanthocyanidin is the parent of plant kingdom's substance that show color, and the derivant that connects various glycosyls claims procyanidin, and the WANZIQIANHONG color that is occurred in plant kingdom all is due to the anthocyanin.Other physiological action then depends on the parent anthocyanidin, and proanthocyanidin belongs to the flavonoid in the polyphenols.Known anthocyanidin has 18 kinds.Proanthocyanidin is an extremely light red brown powder of white, and Fructus Vitis viniferae fragrance and astringent taste are arranged.Water-soluble, ethanol, methanol, acetone etc.Be insoluble to ether, chloroform, because of be by epicatechin and show several theine aggregate into, in acid solution heating back degradable and be oxidized to anthocyanidin, so belong to Flavonoid substances.
Chemical analysis: polyphenols: catechin, epicatechin and gallic acid.
Pharmacological action: 1, antioxidation, slow down aging: procyanidin is the good hydrogen or the donor of neutron owing in its molecular structure electron rich hydroxyl (phenolic group) part is arranged, and very strong oxidation resistance is arranged.Be about 50 times of VE in vivo, be 20 times of VC.According to the laboratory report of French academy of science, think that proanthocyanidin is one of the strongest the most effective free radical scavenger of all discoveries up to now, active especially in vivo, be that other antioxidant is incomparable.Studies show that; proanthocyanidin compares the protective effect of lipid peroxidation in the inductive liver cerebral tissue of TGA (12-0-myristoyl Fo Er alcohol-13-acetas); equal in 100mg/kgGSPE, VC, VE and β one carotene; the result is respectively 40%, 18%, 47% and 16 to the reduction rate that peritoneal macrophage takes place ... use cytochrome reducing process reduction rate to be respectively 65%, 15%, 37% and 19%; explanation has protective effect to oxidative damage, and is better than other antioxidant.Under this external 120mg/L concentration, to the inhibition ability of superoxide anion and hydroxyl radical free radical.GSE is 78% and 81%, and VC is 12% and 19%, and VE50% and 75% illustrates that GSE is a kind of stronger free radical scavenger, thereby alleviates the free-radical oxidation damage and the aging of tissue.
GSE can see through blood brain barrier and provide the anti-oxidation protection effect to brain cell, and the effect of prevention presenile dementia is arranged, and to stablize blood brain barrier, makes to be harmful to the chamber material and can't to enter brain and brain is shielded.
2, to the antioxidation of biological tissue: experimental result shows, average poly-and degree is that the effect that proanthocyanidin has the strongest delay blood plasma oxidation induction period is crossed in 10 the high polymerization of GSE, on average getting right is GSE master of mixed type of 7 (all P<0.05), average degree of polymerization is that 2.5 low polymerization degree proanthocyanidin takes second place again, but all be eager to excel than the effect of VE and VC, the matched group that does not add any polyphenoils is the poorest.
3, blood fat reducing: it is reported, someone is separated into monomer and polymer (poly-anthocyanidin) with GSE, sneaks in the rat low fat feedstuff and (accounts for 2%), to study its influence to the various lipids of rat, as normal group, is matched group with the solid beverage of the high gallbladder that does not add GSE with common low fat beverage.The polymer group can significantly reduce the content of T-CHOL (TC), triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C) and low density lipoprotein, LDL (VLDL) in the feeding hypercholesterolemia beverage rat plasma as a result, and the content of raising HDL-C (HDL-C), in addition, according to the result who measures cholesterol in the big Oletum Ratti norvegici simultaneously, show the cloudy absorption that ends digestive tract to cholesterol of GSE poly physical ability, a large amount of cholesterol therefore in the rat feces of high fat diet, occurs.
Other has experimental result to show, the Mus great and mighty or powerful that nursing contains the GSE beverage is after 6 weeks, and triglyceride and cholesterol in rat blood serum and the spleen all decrease, and serum cholesterol descends 18.1%, and serum triglyceride level reduces by 34.4%.
4, bring high blood pressure down and protect cardiovascular and cerebrovascular vessel: the oxidation hardening gradually of the elastic fiber in the blood vessel is to cause hypertensive main cause.OPC among the GSE can bring high blood pressure down by improving blood vessel elasticity.Experimental results show that, OPC can reduce cholesterol levels in the blood, cholesterol deposits and inhibition angiotonase activity are to bring high blood pressure down on the minimizing blood vessel wall, other experimental results show that, in the rat beverage, add OPC, chromium, the zinc composition of GSE, and the test group blood pressure is starkly lower than matched group, and its mechanism is the formation that OPC has reduced free radical, has improved the sensitivity of insulin.
5, suppress tumor: it is reported, the external test of OPC (25mg/L) that human GSE is arranged, result's proof is to the MCF-7 mankind mastopathy cell, A-427 Human Lung Cancer cell, human adenocarcinoma of stomach cell of CRL-1739 and the chronic bone marrow leukemia cells of K562 have cytotoxicity, they 24 hours, 48 hours, 72 hours growth inhibition ratio is respectively 7%, 30%, 43% simultaneously, OPC can improve the growth and the survival ability of normal human subject mucosa cell and normal J774AI urothelial cell, once after giving 300mg/d28 days to 92 phlebangioma patients, the disappearance of keenly feeling of the people more than 75%.
6, radioprotective: it is reported lotus S180 sarcoma mice is carried out local irradiation with 60 ℃ gamma ray respectively, or per os gives GSE and carry out local irradiation simultaneously, behind the inoculation oncocyte the 12nd day, detect indexs such as tumor weight, numeration of leukocyte.The result shows that the average tumor weight average of contrast level is higher than other rank, and the tumor control rate that irradiation adds GSE is higher than irradiation and simple GSE group.In addition, GSE can reduce the raising of MDA due to the irradiation, and is dose-effect relationship, illustrates that GSE can suppress the lipid peroxidation that is caused by radiation.
7, skin maintenance: studies show that proanthocyanidin is to be the most effective Natural antioxidant naturally at present, has the ability of extremely strong removing free radical, have the title of oral cosmetics, simultaneously, proanthocyanidin can effectively reduce pigmentation, prevents Dermatochalasia.According to another report, GSE can stop and participate in to form chloasma melanin tyrosinase activity, can suppress 50% melanic generation, can suppress the pigmentation that caused by ultraviolet radiation in addition, thereby reaches the effect of skin whitening.Can also block the generation and the activity thereof of elastoser in the skin, thereby improve elastin laminin for want of and the Dermatochalasia that produces, phenomenons such as wrinkle.So claim GSE that the good reputation of skin vitamin is arranged the America and Europe.
8, improve asthenopia: discover, give the asthenope of 75 examples because of working for a long time with proanthocyanidin before display screen, give 300mg every day, after 2 months, its relative number perception and nbjective symptom all have clear improvement.Took proanthocyanidin 150mg/d 2 totally months for 200 myopia retina inflammatory patients, experimenter's vision is significantly improved as a result.
In addition, proanthocyanidin is also had effects such as enhancing immunity, mutation, antiallergic, anti-inflammatory, relieving constipation, fat-reducing, improvement memory.
In sum, this product has slow down aging, care ovary, effects such as skin maintenance.
Processing technology:
1, allotment mixes, and gets and hides Adeps caprae seu ovis element, Stigma Croci extract, hides wolfberry fruit extract, hides Rhizoma Polygonati extract, the ZANGDANGGUI extract, the Dioscorea deltoidea Wall.ex Griseb. extract, raw materials such as Radix Polygoni Multiflori extract, Sargassum extract, vitamin B6, vitamin E, vitamin C mix, and stir.
2, capsule is filled: the raw material that stirs is sent into filling machine, raw material is filled in the capsule.
3, seal:, seal mouth by quality standard with populated capsule.
4, test package: will seal the capsule of mouth, through being up to the standards, packing becomes formal product.
It is that the raw material in the component design is mixed by its physics and chemistry rerum natura that allotment mixes, well-beaten uniform operation, and this operation gets raw mix.It is the mixed material that preceding operation is made that capsule is filled, and is filled in the operation in the capsule.It is that the capsule of populated raw material carries out sealing process that capsule seals, and this process is for capsular material composition does not consume and the capsule opening, draws operation and gets the semi-finished product capsule.Test package is the semi-finished product capsule with first operation system, and through being up to the standards, packing becomes the operation of formal product.
Six, quality standard:
1 physical and chemical index:
Tibet sheep placental extract: g/100g 11.6
Stigma Croci extract g/100g 2.9
Hide wolfberry fruit extract g/100g 14.5
Hide Rhizoma Polygonati extract g/100g 10.0
ZANGDANGGUI extract g/100g 11.5
Rhizoma Dioscoreae extract g/100g 14
Radix Polygoni Multiflori extract g/100g 12.0
Sargassum extract g/100g 13.2
Former flavochrome g/100g 8.7
Vitamin A mg/100g 1.2
Vitamin E mg/100g 45
Vitamin C g/100g 5.8
Vitamin B 6Mg/100g 30
2, instructions of taking: every day three times, each 0.7 gram-1 gram, one after each meal.
The specific embodiment:
Embodiment: get 4 kilograms of sheep placental extract, 1 kilogram of Stigma Croci extract, hide 5 kilograms of wolfberry fruit extracts, hide 4 kilograms of Rhizoma Polygonati extracts, 4 kilograms of ZANGDANGGUI extracts, 4.5 kilograms of Rhizoma Dioscoreae extracts, 4.5 kilograms of Sargassum extracts, 4 kilograms of Radix Polygoni Multiflori extracts, 3 kilograms of proanthocyanidins, vitamin A 0.4 gram, vitamin e1 50 grams, vitamin B 6100 grams, the Catergen kilogram.Mix Deng raw material, stir, send into filling machine raw material is filled in the capsule, capsule seals, and the packing that is up to the standards becomes formal product.

Claims (2)

1, the sheep placenta capsule compound nest-defence capsule for beautifying face processing technology is: allotment mixes, and stirring, capsule are filled, and capsule seals, test package becomes formal product,
2, process conditions are: 4 kilograms of Tibet sheep placental extract, 1 kilogram of Stigma Croci extract, 5 kilograms of the wolfberry fruit extracts in Tibetan, 4 kilograms of the Rhizoma Polygonati extracts in Tibetan, 4 kilograms of ZANGDANGGUI extracts, 4.5 kilograms of Rhizoma Dioscoreae extracts, 4.0 kilograms of Radix Polygoni Multiflori extracts, 4.5 kilograms of Sargassum extracts, 3 kilograms of proanthocyanidins, vitamin A 0.4 gram, vitamin B6 100 grams, vitamin e1 50 grams, Catergen kilogram, mix, stir Deng raw material, capsule is filled, capsule seals, test package becomes formal product.
CNA2008100999072A 2008-05-17 2008-05-17 Sheep placenta capsule compound nest-defence capsule for beautifying face Pending CN101284096A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102641397A (en) * 2012-03-30 2012-08-22 常熟市海虞茶叶有限公司 Sheep placenta-containing composite capsule and preparation method thereof
CN103007174A (en) * 2012-12-28 2013-04-03 东兴市仁健养生保健有限公司 Beautifying and whitening pill and preparation method thereof
CN104126744A (en) * 2014-07-01 2014-11-05 苟春虎 Lycium ruthenicum Murr anti-agingbeauty tablet
CN104288432A (en) * 2014-09-17 2015-01-21 苟春虎 Female Viagra capsule
CN108813246A (en) * 2018-05-31 2018-11-16 陕西顾森健康科技有限公司 A kind of easy anti-ageing composition of collagen peptide and its preparation process for absorbing Anti-lost

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102641397A (en) * 2012-03-30 2012-08-22 常熟市海虞茶叶有限公司 Sheep placenta-containing composite capsule and preparation method thereof
CN102641397B (en) * 2012-03-30 2013-12-25 太仓市临江农场专业合作社 Sheep placenta-containing composite capsule and preparation method thereof
CN103007174A (en) * 2012-12-28 2013-04-03 东兴市仁健养生保健有限公司 Beautifying and whitening pill and preparation method thereof
CN103007174B (en) * 2012-12-28 2014-07-02 东兴市仁健养生保健有限公司 Beautifying and whitening pill and preparation method thereof
CN104126744A (en) * 2014-07-01 2014-11-05 苟春虎 Lycium ruthenicum Murr anti-agingbeauty tablet
CN104288432A (en) * 2014-09-17 2015-01-21 苟春虎 Female Viagra capsule
CN108813246A (en) * 2018-05-31 2018-11-16 陕西顾森健康科技有限公司 A kind of easy anti-ageing composition of collagen peptide and its preparation process for absorbing Anti-lost

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