CN102210838A - Medicinal composition for strengthening immunity and improving human body condition - Google Patents

Medicinal composition for strengthening immunity and improving human body condition Download PDF

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CN102210838A
CN102210838A CN2010101469545A CN201010146954A CN102210838A CN 102210838 A CN102210838 A CN 102210838A CN 2010101469545 A CN2010101469545 A CN 2010101469545A CN 201010146954 A CN201010146954 A CN 201010146954A CN 102210838 A CN102210838 A CN 102210838A
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肖嘉惠
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Abstract

The invention relates to a medicinal composition for strengthening immunity and improving human body condition. The medicinal composition is prepared from medicines such as nutgrass galingale rhizome, zedoary, finger citron, costustoot, Chinese eaglewood, bitter orange, peach seed, safflower, pangolin scales, mongolian snakegourd root, root of red-rooted salvia, cassia twig, bupleurum, platycodon root and the like. The medicinal composition has the good effects of treating memory insufficiency or deterioration, physical weakness and low working capability of the juvenile, the young people, the middle-aged people, and people in the prime of life, also has the effects of strengthening intelligence, building bodies, prolonging life, and rejuvenating of the elderly people.

Description

A kind of enhance immunity, improve the pharmaceutical composition of human body constitution
Technical field
What the present invention relates to is that a kind of the training mended the multiple weak disease that congenital defect causes, be a kind of training mend less, blue or green, prime of life learning capacity is low, have bad physiques, ability to work goes down and dull-witted and rejuvenescent medicine.
Technical background
The people that the mankind do not have memory, body constitution muscle power, ability to work not to go down, do not wane, this medicine can make people's whole body be taken a tonic or nourishing food to build up one's health, and has removed 15 reasons that cause human senility, so played slow down aging, rejuvenescent effect.
Summary of the invention
The purpose of this invention is to provide and a kind ofly can mend congenital defect, Fructus Alpiniae Oxyphyllae is kept fit, the rejuvenation medicine.
The present invention comprises following component by weight:
Rhizoma Cyperi 10; Radix Curcumae 12; Fructus Citri Sarcodactylis 10; the Radix Aucklandiae 8; Lignum Aquilariae Resinatum 3; Fructus Aurantii 15; Semen Persicae 12; Flos Carthami 12; Squama Manis 6; pollen 10; Radix Salviae Miltiorrhizae 30; Ramulus Cinnamomi 10; Radix Bupleuri 12; Radix Platycodonis 12; Radix Achyranthis Bidentatae 12; Radix Ginseng Rubra 6; the Rhizoma Atractylodis Macrocephalae 18; Poria 20; Radix Glycyrrhizae Preparata 12; 8 in Fructus Jujubae; Radix Angelicae Sinensis 12; Radix Rehmanniae Preparata 18; the Radix Paeoniae Alba 15; Rhizoma Chuanxiong 9; Placenta Hominis 15; Colla cornus cervi 6; the Cortex Eucommiae 10; Herba Cistanches 12; Carapax et Plastrum Testudinis 30; Colla Plastri Testudinis 6; Colla Corii Asini 15; Fructus Lycii 12; Radix Asparagi 12; Radix Ophiopogonis 12; the Radix Rehmanniae 12; Cortex Phellodendri 10; Semen Armeniacae Amarum 12; Fructus Hordei Germinatus 20; Fructus Setariae Germinatus 20; burnt short, bristly hair or beard 18; Massa Medicata Fermentata 18; Semen Raphani 12; chicken gold 10; Arillus Longan 18; Semen Ziziphi Spinosae 20; Poria cum Radix Pini 30; Os Draconis 30; Rhizoma Acori Graminei 12; Radix Polygalae 10; Calculus Bovis 0.6; Cinnabaris 0.3.
Medicine comprises following component by weight:
Rhizoma Cyperi 0.1-10, Radix Curcumae 0.1-12, Fructus Citri Sarcodactylis 0.1-12, Radix Aucklandiae 0.1-18, Lignum Aquilariae Resinatum 0.1-15, Fructus Aurantii 0.2-20, Semen Persicae 0.2-18, Flos Carthami 0.1-200, Squama Manis 0.1-300, big pollen 0.01-100, Radix Salviae Miltiorrhizae 0.1-300, Ramulus Cinnamomi 0.1-50, Radix Bupleuri 0.1-92, Radix Platycodonis 0.2-68, Radix Achyranthis Bidentatae 0.2-212, Radix Ginseng Rubra 0.1-166, Rhizoma Atractylodis Macrocephalae 0.1-218, Poria 0.1-320, Radix Glycyrrhizae Preparata 0.1-212, Fructus Jujubae 0.1-268, Radix Angelicae Sinensis 0.1-212, Radix Rehmanniae Preparata 0.1-218, Radix Paeoniae Alba 0.1-215, Rhizoma Chuanxiong 0.1-219, Placenta Hominis 0.1-315, Colla cornus cervi 0.1-126, Cortex Eucommiae 0.1-210, Herba Cistanches 0.1-212, Carapax et Plastrum Testudinis 0.1-530, Colla Plastri Testudinis 0.1-216, Colla Corii Asini 0.1-215, Fructus Lycii 0.1-312, Radix Asparagi 0.1-212, Radix Ophiopogonis 0.1-192, Radix Rehmanniae 0.1-512, Cortex Phellodendri 0.1-210, Semen Armeniacae Amarum 0.1-212, Fructus Hordei Germinatus 0.1-99, Fructus Setariae Germinatus 0.1-120, burnt short, bristly hair or beard 0.1-598, Massa Medicata Fermentata 0.1-218, Semen Raphani 0.1-312, chicken gold 0.1-210, Arillus Longan 0.1-318, Semen Ziziphi Spinosae 0.1-220, Poria cum Radix Pini 0.1-330, Os Draconis 0.1-430.
We are with Rhizoma Cyperi, Radix Curcumae, Fructus Citri Sarcodactylis, Radix Aucklandiae liver-smoothing, qi-regulating, with Lignum Aquilariae Resinatum, Fructus Aurantii remove the stasis of blood for many years stagnate in the part of the body cavity above the diaphragm housing the heart and lungs against gas, thereby help removing the whole body qi depression to blood stasis; With Semen Persicae, the promoting the circulation of blood of Flos Carthami removing blood stasis with potent drugs, pollen is moisturized repercussive, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, the logical whole body blood vessels of Ramulus Cinnamomi, and Squama Manis, the Radix Paeoniae Alba, Radix Angelicae Sinensis activating blood circulation and dissipating blood stasis, Squama Manis draw all medicines and go into brains, the vital organs of the human body and whole body muscles and bones; Radix Bupleuri draws all medicines top, sensible mountain peak under the breast, removes the blood stasis that amasss at upper body; With Fructus Aurantii, the soothing the liver circulation of qi promoting of Radix Platycodonis, open the breast eliminating stagnation; The Radix Achyranthis Bidentatae conducting blood to flow downwards; Radix Glycyrrhizae and middle relieving spasm to stop pain, all medicines share the stagnant gas blood stasis that accumulates is for many years dissipated and the circulation of hyperamization arteries and veins, and gains in depth of comprehension are supported, and the machine of gods is got well.
Long-term worried, impairment caused by overstrain heart spleen is so with Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, Poria, Rhizoma Zingiberis Recens, Fructus Jujubae QI invigorating spleen reinforcing hemopoietic, make QI and blood biochemistry active; With the Radix Angelicae Sinensis hemopoietic of invigorating blood circulation, Radix Rehmanniae Preparata nourishing YIN and supplementing blood, Radix Paeoniae Alba QI and blood regulating, yin fluid astringing benefit blood, the Rhizoma Chuanxiong regulating qi and activating blood plays the effect of qi and blood tonifying; With Placenta Hominis strongly invigorating QI and blood and nephroyin and nephroyang; Mend with Colla cornus cervi and smartly to give birth to marrow and beneficial Yuanyang, the Cortex Eucommiae, Herba Cistanches further help the Colla cornus cervi enrich and benefit essence and blood, sufficient yang-energy and dredging DU Meridian arteries and veins; With the method for kidney-replenishing, improve because of the years damage causes kidney yang deficiency, give birth in the dysfunction of the spleen in warming, phlegm-damp, hoodwink the aging state that key clearly occurs, promptly so-called " high space according to and YIN pulse from loosing also "; Mend Tianjin blood and benefit is Kidney-Yin with Carapax et Plastrum Testudinis, the Colla Corii Asini kidney nourishing water, Radix Rehmanniae Preparata, Fructus Lycii YIN nourishing liquid, Kidney-Yin to mend the people, strengthen the Carapax et Plastrum Testudinis Kidney-Yin effect of benefit and logical conception vessel, promptly so-called " dark native must the profit and sun burn go so also "; Radix Asparagi, Radix Ophiopogonis, Radix Rehmanniae lung moistening nourishing YIN are promoted the production of body fluid; Make each positions of whole body such as the heart, liver, spleen, lung, kidney, stomach, intestinal, gallbladder, bladder, brain, bone, marrow, QI and blood, spirit, kidney water, cloudy liquid, fur, libido and reproductive function of people obtain tonification.Cortex Phellodendri fire is clearly mutually more arranged, the constipation of the anti-stagnation of QI of Semen pruni armeniacae is obstructed, the dryness of the lung cough with asthma that the solar heat protection guiding drug rises, so that big benefit the and do not have the worry of heat-blockage dryness accumulated in the stomach and intestine, more there are Fructus Hordei Germinatus, Fructus Setariae Germinatus, burnt short, bristly hair or beard, Massa Medicata Fermentata, Semen Raphani, chicken gold facilitating digestion to absorb various elite materials and satisfy bone to give birth to marrow, kidney storing essence, battalion's waist kidney, waist knee joint strong strong and vigorous, physical agility, can treat the congenital obstinate disease of each age period, make crippled's rehabilitation for many years, make less, blue or green, prime of life body constitution is more strong, memory is better, and the daring of adolescence appears in the old people, and shows off the merit of rejuvenation.
Owing to excessive thinking, heart spleen blood deficiency take place the insomnia forgetfulness palpitation with a distress feeling,, then heart spleen is injured for a long time, nutrient blood is empty few, so nourish blood with Arillus Longan, Semen Ziziphi Spinosae, Radix Polygalae, Poria cum Radix Pini, Os Draconis, Radix Angelicae Sinensis reinforcing the heart, Radix Ginseng, the Radix Astragali, Radix Glycyrrhizae, Rhizoma Atractylodis Macrocephalae spleen reinforcing hemopoietic, nutritious blood abundance, painstaking effort abundance then, gains in depth of comprehension are supported, heart spleen must be supported, brain brims over, and god can keep house ability Sufficient Sleeping, the brain of the god's of unit internal organs, obtain omnibearing recovery and renewal, reach equilibrium between yin and yang, mend the congenital foundation and the illustrious and influential power of compensating renewal, so that the merit of Shi Now rejuvenation.Simultaneously with Rhizoma Acori Graminei, Radix Polygalae restoring normal coordination between the heart and kidney calming the nerves, Calculus Bovis, Cinnabaris eliminating phlegm and calming wind, the arresting convulsion relieving palpitation, the Fructus Alpiniae Oxyphyllae of calming the nerves, the efficacy of a drug of full side can make people's god, residence is in the heart, the essence of the heart depends on kidney, the brain being the house of mentality, the sea of marrow, real memory is rented also.As seen this side has restoring normal coordination between the heart and kidney, makes under the gods of the heart to lead in kidney, is melted into brain on the elite of kidney, smart can be angry, gas can be given birth to god, it is clear that god decides gas, the mistake of forgeing from aquatic foods.
Modern medicine study proves:
(1) vital energy regualting and blood circulation-promoting medicine: Rhizoma Cyperi 10, Radix Curcumae 12, Fructus Citri Sarcodactylis 10, the Radix Aucklandiae 8, Lignum Aquilariae Resinatum 3, Fructus Aurantii 15, kernel 12, Flos Carthami 12, Squama Manis 6, the Radix Paeoniae Alba 15, Radix Angelicae Sinensis 10, Radix Trichosanthis 10, Radix Salviae Miltiorrhizae 30, Rhizoma Chuanxiong 9, Ramulus Cinnamomi 10, Radix Bupleuri 12, Radix Platycodonis 12, Radix Achyranthis Bidentatae 12;
Rhizoma Cyperi: cyperol has refrigeration function, and normal body temperature is descended, and obviously improves the pain valve; Spontaneous activity is reduced, slow, and can eliminate conditionality and avoid reflection; Ileum smooth muscle there is direct repression, and can resists the contraction of myenteron, bronchospasm is had protective effect.Heart is had heart tonifying and decreased heart rate effect, can make heart beating stop at systole, blood pressure is reduced; Can part the effect of blocking histamine, can promote bile secretion, improve bile flow, the hepatocyte injury that carbon tetrachloride is caused has protective effect, and staphylococcus aureus etc. is had inhibitory action.Strong choleretic effect is arranged.
Radix Curcumae: 1, the splenocyte vitro conversion is had the obvious suppression effect.Can prolong sleep, hippocampal slices CAlp pyramidal cell group be brought out field potential produce the obvious suppression effect.Can reduce propylhomoserin aminotransferase in the carbon tetrachloride poisoning serum, increase the content of total serum protein, albumin, hepatomicrosome cytochrome and liver reduced glutathion.Can reduce erythrocytic aggregation, ability is sticked in raising erythrocyte deformability and antioxidation, immunity.Reduce the damage of radical pair erythrocyte membrane, prolong its life-span, safeguard normal blood viscosity, improve hemorheological property.Can cause lipid peroxide content to increase.
Fructus Citri Sarcodactylis: 1, FRUCTUS CITRI SARCODACTYLIS from Sichuan of China can shrink the isolated tracheal that antihistamine causes, citropten. shrinks histamine intestinal and isolated tracheal, to the ileum and the isolated tracheal of Ovum Gallus domesticus album sensitization, shows antiallergic activity.2, Fructus Citri Sarcodactylis has obvious spasmolysis to intestinal tube, and intravenously administrable has inhibitory action to intestinal tube, and the duodenum spasm that acetylcholine is caused has significant spasmolysis, and the tension force that the quiet notes of alcohol extract can be alleviated stomach, intestinal and gallbladder rapidly increases.3, can suppress antimony potassium tartrate and electricity and swash the pain sensation reaction that causes, visible writhing response number of times minimizing and the pain sensation response time of shouting prolong, and show certain analgesic activity.4, can increase the coronary flow and the raising hypoxia-bearing capability of heart, the myocardial ischemia that causes because of pituitrin is had protective effect, the arrhythmia that chloroform, epinephrine are caused also has preventive effect.5, the sufficient sole of the foot that causes of diosmin on Carrageenan is swollen a detumescence effect.
The Radix Aucklandiae: 1, enterokinesia amplitude and flesh intestinal tension force are obviously strengthened, flesh enterospasm is had antagonism; 2, can promote the secretion of somatostatin, and have choleretic effect.3, the effect of rising blood pressure is arranged.4, can suppress that writhing response, ear are swollen, the raising of foot swelling and abdominal cavity capillary permeability, antiinflammatory action is arranged, and can significantly reduce alkali phosphatase, acid phosphatase, r-glutamyl transpeptidase, and the protein level that can raise and reduce.5 can suppress nitric oxide production synthetic, and 6 can improve tumor necrosis factor and lymphocytic killing activity.
Lignum Aquilariae Resinatum: 1, can suppress to exsomatize ileum autonomous contraction and resist spastic contraction; The 2 intestinal ahead runnings that neostigmine is caused slow down, and present the intestinal smooth muscle spasmolysis, reduce gastric antrum circular muscle contraction wave mean amplitude of tide.3, the 2-that contains in the Lignum Aquilariae Resinatum (2-phenethyl) chromone class can obviously prolong the length of one's sleep, and spontaneous activity is reduced, and 5-hydroxy tryptamine content increases.
Fructus Aurantii: 1, can make heart contraction increase, weaken, can cause significant hypertension, the kidney volume reducing, shock has the temporary transient urine effect that presses down.2, can make gastrointestinal motility that significant inhibitory effect is all arranged, contractility is reduced, tonicity descends, and ileum is shunk strengthen having antagonism.Can shorten the mobile complex wave cycle of jejunum, ileum by changing the peak electrical activity of jejunum, intestinal, strengthen the peak electrical activity, shrink mutually the position that strengthens small intestinal, strengthens the emptying of small intestinal.
Semen Persicae: 1, can obviously increase the blood flow of femoral artery, reduce the flow of vascular resistance and perfusate, and can eliminate the blood vessel function that contracts of norepinephrine, the liver surface microcirculation is had some improvement.2, the triolein that contains of Semen Persicae can make bleeding time and the equal significant prolongation of clotting time, also can suppress its blood clot retraction fully.3, stronger anti-carrageenin pedal swelling, granuloma, inflammatory cell and fibroblast proliferative effect are arranged.Remarkable analgesic activity is arranged, suppress writhing response.4, amygdaloside, hydrocyanic acid and benzaldehyde have antitussive effect, and respiratory center is had inhibitory action, can make exaggerated respiration, and cough alleviates, the easy expectoration of expectorant.5, cancerous cell is presented the concertedness lethal effect, make the more accessible cancerous cell of leukocyte in the body, and engulf cancerous cell.
Flos Carthami: 1, to myocardial ischemia, myocardial infarction or arrhythmia etc. all has antagonism in various degree; The acute myocardial ischemia that pituitrin is caused has significant protective effect, and the degree of myocardial ischemia is alleviated, and scope is dwindled, decreased heart rate.And improve the supply-demand relationship of ischemic myocardium oxygen.2, make vascular smooth muscle shrink the vascular tone that keeps certain, the ear that tonicity is increased presents vasorelaxation action; Can increase femoral artery blood flow.Hypotensive effect is in various degree arranged, the obstructive action of the peripheral circulation of improvement is arranged, blood flow is quickened, the open number of blood capillary increases and the hemocyte aggregation extent alleviates.The thrombotic time of obvious prolongation is arranged, shorten the effect of thrombosis length and weight reduction, platelet count is reduced, suppress aggregation capability, prothrombin time and KPTT prolong.3, can reduce the serum total cholesterol of hypercholesterolemia, total fat, triacylglycerol and non-esterified fatty acid level, and can reduce serum cholesterol, the effect of serum cholesterol-lowering regulating liver-QI inner cholesterol and triacylglycerol is arranged.4, can show the raising hypoxia-bearing capability, neuronic degeneration has powerful protectiveness to prevention decompression Hypoxia and ischemia hindbrain.5, intestinal tube spasm due to the acetylcholine there is the effect of spasmolytic.6, can reduce serum lysozyme content, peritoneal macrophage and whole blood phagocytic activity of leukocytes; Make the plaque forming cells, spleen specificity rosette forming cell reduces; The T, the bone-marrow-derived lymphocyte that suppress delayed hypersensitivity and suppressor T cell (Ts) cell activation and participate in.7, writhing response can be suppressed, central inhibitory action can be strengthened; Can also reduce the response rate and the mortality rate of nikethamide convulsions, can alleviate the metabolism disorder of monoamine neurotransmitter in the cerebral tissue again, make the neurotransmitter of decline recover normal, can also neuroprotective unit avoid damage.8, hydroxy radical be can eliminate, hyaluronic acid depolymerization and liver homogenate lipid peroxidation that free radical brings out suppressed.9, can suppress the Streptococcus mutans adhesive ability, reduce bacterial plaque formation amount, anti-fatigue ability in the time of can significantly improving cold tolerance and swimming and the anti-anoxia ability when sodium nitrite poisoning anoxia can also promote its bone lengthening, prevent osteoporosis.
Squama Manis: 1 can significantly increase femoral artery blood flow, reduces Peripheral resistance, and blood vessel wall is had direct dilating effect.2 have the effect of obvious prolongation clotting time, reduction blood viscosity, can significantly reduce blood viscosity and prolong clotting time.The effect of significant anti-ear inflammation is arranged.
The Radix Paeoniae Alba: 1, contained paeonol, benzoylpaeoniflorin and oxidation Radix Paeoniae have antiinflammatory action in the Radix Paeoniae, celebrate, shout and hot plate has obvious inhibitory action left agent arthritis (AA), foot swelling, acetic acid twisting are counter, reduce MDA, NOD and TNF level, enhancement of SOD and GSHPx activity; Also has obvious analgesic activity.2, can promote phagocytic function, pair cell immunity and humoral immunization have potentiation, and AA is had antiinflammatory and function dependent immunity regulating action; Also has dual regulation.Can suppress pathogenic microorganism, 1,2,3,4 in the Radix Paeoniae, 6-five galloyl glucoses have antitoxin activity.3, can suppress spontaneous activity, strengthen the syngignoscism of ciclobarbital soluble and the hypnosis time of prolongation skin barbital sodium, cause the lax of sleep and muscle, also have sedation simultaneously.4, TGP can prolong the normobaric hypoxia time-to-live, reduce pressure the anoxia time-to-live, can reduce the anoxybiotic mortality rate of potassium cyanide poisoning.TG can prolong panting the time behind the disconnected cranium, improves brain electrical acti, reduces brain calcium, sodium, water content.5, can alleviate the T-2 toxin poisoning, aflatoxin be had Degradation external.Can disturb the enzymatic activity of S9 mixed liquor, suppress the mutagenesis of benzopyrene; Wherein gallic acid (GA) and five galloyl glucoses (PGG) can make the metabolite inactivation of benzopyrene, suppress the activity of S9 mixed liquor and the leukopenia due to the MMC.6, can strengthen cancer week lymphocyte enzymatic activity.Can prevent the aldose reductase activity of stress ulcer, eyeglass, the inductive mastocyte histamine release of compound 48/80.7, can be by prolonging the colon contraction time, strengthen the colon shrinkage amplitude and regulate the colon motion.Suppress increasing of ConA and the inductive lymphproliferation response of LPS and IL-1 generation.8, black Chinese herbaceous peony compatibility can strengthen the especially antiinflammatory action of Radix Aconiti of various single medicinal materials, reduces capillary permeability and the content of PGE2 and the toxicity of reduction Radix Aconiti Kusnezoffii in the inflammatory process; 9, reduce blood plasma due to the Radix Aconiti and liver and close that to knit LPO excessive, remove free radical.
Radix Angelicae Sinensis: 1. Radix Angelicae Sinensis can suppress that erythrocyte aggregation strengthens due to the macromolecule right rotary glycoside, suppresses to be sexually revised by the inductive red blood cell deformation of Calcium ionophore, makes erythrocyte that hemolytic time dilation take place in hypotonic medium.2. Radix Angelicae Sinensis polysaccharide can make leukocyte and reticulocyte increase, and erythrocyte, hemoglobin, leukocyte and the femur nucleated cell number of anemia recovered to have apparent facilitation.3. Radix Angelicae Sinensis extracting solution is to single ventricular muscle cell film sodium channel current and L type Calcium Current tool concentration dependent retardation.4. the remarkable coronary artery dilating of eumenol, blood flow increasing can reduce oxygen consumption, the oxygen consumption rate of acute anoxia and strengthens anoxybiotic toleration.(1) acute myocardial ischemia and the acute myocardial infarction of energy antagonism pituitrin and caused by ligature reduce myocardial oxygen consumption, increase cardiac muscle picked-up and arteria coronaria flow, reduction myocardial contraction amplitude.(2) the myocardial ischemia reperfusion injury myocardial infarction area is significantly dwindled, impel Protein kinase C to transfer to cell membrane from nucleus, activated protein kinase C suppresses myocardial ischemia reperfusion injury.(3) can arrhythmia short of money, and ventricular muscles irregularity of pulse due to the cardiac glycoside.(4) can accelerate the blood circulation of cerebral tissue, improve neuronic metabolism, reduce middle cerebral artery thromboembolism cerebral infarction area, nerve growth and reparation associated protein behind the promotion cerebral ischemia, promote nerve cell adhesion molecule and the expression that promotes microtubule-associated protein, reduce apoptotic generation.The apoptosis of double blanking bar of expression that (5) can be by promoting bcl-2 produces inhibitory action.Can make vasodilation, arterial pressure descends, and arteria coronaria, cerebral arteries and femoral artery resistance descend, and blood flow increases.5. Radix Angelicae Sinensis injection can suppress aorta VSMC propagation, may with its increase SOD activity, rising PG12, cAMP level reduce lipid peroxidation product, and it is relevant to suppress the expression of proliferating cell nuclear antigen among the VSMC.6. Radix Angelicae Sinensis slows down vascellum endometrial hyperplasia by suppressing the conversion of VSMC phenotype, points out its potential therapeutical effect to atherosclerosis and percutaneous coronary endoluminal vascular shaping postoperative restenosis to the VSMC inhibition of proliferation.7. Radix Angelicae Sinensis can promote vein endothelial cell propagation and DNA to synthesize.Can make the unusual distribution and the expression of the intercellular adhesion molecule-1 that under the shearing force effect, makes EVC304 be tending towards normal.8. Radix Angelicae Sinensis, sodium ferulate can alleviate the EVC304 Ultrastructural damage of hyperlipemia due to clear effectively; And the expression of TGF-β 1 in the cell is obviously increased, the expression of bFGF reduces.(1) can reduce hyperlipemia triacylglycerol level, improve hemorheology index, the reduction of antagonism aorta nitric oxide level and the rising of plasma ET have study of anti-atherogenic effect.(2) can cause the rising that endotheliocyte secretion nitric oxide descends and ICAM-1 expresses by the antagonism OxLDL ELISA.The angelol hypostasis can promote the effect of spleen and thymus T, bone-marrow-derived lymphocyte propagation.(3) can resist the inhibitory action of andrographolide to inductive spleen and thymus T lymphproliferation response.(4) function of the strong cytotoxic T cell in energy border, its killing activity increases.9. the Radix Angelicae Sinensis extracting solution quantity of hepatic tissue internal specific antibody of schistosomicide that can significantly raise.10. Radix Angelicae Sinensis can promote splenocyte propagation, and immunoadjuvant function is arranged.Can obviously improve its antibody quantity and tire.Can strengthen the phagocytic activity of M Φ, improve NO content, improve the defense function of peritoneal cavity M Φ, reduce the incidence rate of peritonitis.11. Radix Angelicae Sinensis can obviously promote spleen lymphocyte proliferation, induces splenocyte secretion 1FNr, strengthens the biological activity of 1FNr.But the antagonism exogenous androgen is to the prostate effect of gain of the male and endogenous androgen of castration to normal male.Can suppress hypophysis secretion lutropin and prolactin antagonist, but also antagonism promoting sexual gland hormone zest hormone release causes that damage of female individuals corpus luteum and plasma progesterone level reduce, and causes miscarriage, discharges minimizing at the male testosterone that causes.12. Radix Angelicae Sinensis can significantly reduce collagen content, alleviates hepatic fibrosis.Can reduce Serum ALT and glutathion S-transferase activity, increase glutathione reductase activity in the hepatocyte.13. Radix Angelicae Sinensis water extract, volatile oil or sodium ferulate all have obvious facilitation to choleresis, and increase the excretion of solids and cholic acid in the bile.The stripped intestinal segment that Radix Angelicae Sinensis causes Ach shrinks inhibitory action is arranged, can suppress the diarrhoea that Oleum Ricini causes, it is then invalid that Folium Sennae causes diarrhoea, can also suppress gastrointestinal propulsion, can alleviate the dabbling again degree of injury of renal ischaemia, may with the content of atpase activity in its raising nephridial tissue and bFGF and relevant to the regulation and control of cytokines such as TNFa, IL-6 and bFGF.14. Radix Angelicae Sinensis injection is local branch injection in the ear hypertrophic cicatrix; can obviously reduce fibroblast quantity and collagen content in the scar tissue; alleviate the cicatrix fibrosis. (1) can adjust acute hemorrhage necrotizing pancreatitis TXA2, PGI2 ratio, corrects the effect that has renal function protecting unusually of hemorheology.(2) can suppress aorta VSMC propagation, may with its increase SOD activity, rising PG12, cAMP level reduce lipid peroxidation product, and it is relevant to suppress the expression of proliferating cell nuclear antigen among the VSMC.(3) can significantly alleviate acute lung injury alveolar degree of inflammation, reduce the secretion of pneumonia medium, suppress the generation of malonaldehyde.(4) can reduce bleomycin and cause pulmonary fibrosis lung coefficient, alleviate alveolitis and pulmonary fibrosis, suppress fibronectin and increase, reduce MDA generation in the lung, reduce blood and lung homogenate hydroxyproline content, alleviate the pulmonary fibrosis pathological changes, delay the fibrosis process.(5) can suppress the inductive liver lipid peroxidation effect of oxygen-derived free radicals generation systems.(6) can obviously improve the cerebral cortex enzymatic activity, reduce its content and activity, high dose defying age effect is more satisfactory.15. Radix Angelicae Sinensis to climacteric cardiovascular system important protective effect is arranged.(1) the radiation damage chromosome aberrations rate is obviously descended, can show reproductive function after the protection radiation damage, DNA and rna content in follicular cell and the oocyte are raise, ovarian structure and function are protected, and can also show raising hepatic tissue SOD activity.The preventative Radix Angelicae Sinensis polysaccharide that gives can significantly promote to be subjected to prevent the thymus secondary atrophy according to bone marrow and spleen hematopoietic function recovery, improves the irradiation survival rate, is showing the recovery that promotes granuloid committed precursor cell to generate unit and pluripotential hemopoietic stem cell formation unit.To ascitic type tumor and ascitic type leukemia, can delay ascites and produce, prolong the time-to-live.(2) the acute and chronic inflammation that multiple proinflammatory agent is caused all has significant inhibitory effect, and its antiinflammatory action still exists behind the excision bilateral adrenal gland, and can reduce the burst size of inflammation tissue, reduces the other hemolytic activity of complement.(3) but the significant prolongation hyperbaric oxygen causes the incubation period of fainting from fear, can reverse the abnormal change of amino acid neurotransmitter in the brain.(4) can alleviate the degree of sciatic nerve class damage, can accelerate the aixs cylinder germination process and promote reinnervation, have the effect of the neuranagenesis of promotion, this effect may to improve nerve metabolism relevant with it.
Radix Trichosanthis: 1. Radix Trichosanthis causes the miscarriage effect, can promote latter half of gestation, strengthens the spontaneous activity in its uterus on the throne, also can improve gravid uterus prostaglandin content, ketone concentration is educated in blood plasma and uterus then do not have obvious influence.2. trichosanthin has damaging action to the blastocyst in pregnancy period, and tangible antiearly pregnancy effect is arranged.Can suppress the growth of malignant tumor, the transplanting of lotus people hepatocarcinoma is had tangible cancer suppressing action, also have two kinds of effects of immunostimulation and immunosuppressant simultaneously.3. trichosanthin can suppress HIV (human immunodeficiency virus) (Human Immunodeficiency Virus).
Radix Salviae Miltiorrhizae: 1. Radix Salviae Miltiorrhizae water extract can prevent or reduce the generation that is caused ventricular fibrillation by isoproterenol, improves survival rate.2. Radix Salviae Miltiorrhizae Injection can have dilating effect to blood vessel by obvious renal blood flow increasing, and Radix Salviae Miltiorrhizae has hypotensive effect in various degree.Coronary flow is obviously increased, and coronary resistance obviously descends, but myocardial oxygen consumption increases to some extent.Radix Salviae Miltiorrhizae Injection, in local cerebral ischemia reperfusion stream damage prevention and treatment, no matter treatment group still is the prevention group, and infarct size all obviously dwindles, and only has mild cerebral ischemic to change individually, and demonstrating Radix Salviae Miltiorrhizae has sure prevention and therapeutical effect to acute cerebral ischemia.Radix Salviae Miltiorrhizae Injection can prolong the survival period of cardiac muscular tissue, alleviates the blood capillary damage, and protecting myocardial cell alleviates immunocyte and soaks into, and the rejection of energy facedown body fluid and cellular immunization.3. the obvious coronary artery dilator of danshensu significantly increases coronary flow, and sodium tanshinone IIA sulfate, former youngster's naphthaldehyde etc. significantly shrink isolated coronary, and the different monomers chemical compound of prompting Radix Salviae Miltiorrhizae is not the same to effect coronarius.Effect to myocardial ischemia and myocardial infarction; salvianolic acid A can reduce the incidence rate owing to quiver in the chamber that myocardial ischemia-reperfusion causes; reduce LDH spilling from cell space; reduce MDA content in the ischemic myocardial tissue, thereby damage has the certain protection effect to the proof salvianolic acid A to myocardial ischemia-reperfusion.There is obvious inhibition neutrophil lysosome to discharge to myocardial infarction, engulfs and stick, the effect of control myocardial infarction is arranged.Danshensu has effect, rising hypercholesterolemia liver and the fibrocyte acceptor levels that reduction cell inner cholesterol is synthetic and the lipotropism electrophoretic mobility of protein obviously slows down.4. Radix Salviae Miltiorrhizae has calcium channel blocking action to cardiac muscle.Radix Salviae Miltiorrhizae has anticoagulation, and thrombus formation time is prolonged, the thrombosis contraction in length, and thrombosis dry weight and weight in wet base alleviate, and platelet adhesion reaction and aggregation capability reduce.The life span of Radix Salviae Miltiorrhizae energy significant prolongation anoxia enduring.Macrophage phagocytic percentage rate and phagocytic index are obviously improved, and spleen antibody generates number and obviously improves, and Radix Salviae Miltiorrhizae is having facilitation aspect the raising humoral immune function.Also can reduce the phagocytic percentage and the phagocytic index of peritoneal macrophage, make the delayed hypersensitivity of lymphocytic conversion ratio decline of T and inhibition normal foot pad.5. TANSHINONES increases the vascular permeability that histamine causes, to acute swollen joint and to exudative formaldehyde peritonitis reaction obvious inhibitory action is arranged all; Leukoplania and subacute formaldehyde swollen joint all there is the obvious suppression effect.TANSHINONES can make prostaglandin level reduction in the blood.Deferrable and alleviate behind the ischemia again the irreversibility hepatic injury that perfusion causes.Liver regeneration degree, karyokinesis phase index, alpha-fetoprotein recall rate are all increased.Improve the liver blood circulation, increase the pancreas hyperglycemia, improve hepatic glycogen, reduce the liver fat content, promote the generation of RNA, DNA, this is to promoting that liver regeneration has certain effect.Carbon tetrachloride causes chronic hepatic injury that the hepatic fibrosis hyperplasia degree is obviously alleviated.Inhibition fibroplasia is arranged, prevent cirrhotic generation.Established fiber is dissipated and absorption.TANSHINONES has antihepatocarcinoma effect, and salvianolic acid A has the tumor cell of inhibition nucleoside transport activity, and cancerous cell is had lethal effect.Growth to pulmonary carcinoma, melanoma and sarcoma has inhibitory action, and leukemic life span is obviously prolonged.Can obviously alleviate the order of severity of alveolitis, reduce lung weight, and can suppress the generation of lipid peroxide, the acute lung injury of preventing bleomycin to cause is arranged.Tanshinone can effectively suppress the cytolipin peroxidating, reduces lipid-DNA addition product and produces.Tanshinone is a kind of new, effective lipid within endothelial cells peroxidating product and the interactional inhibitor of DNA.Salvianolic acid A suppresses cataractous formation by antioxidation.Distribution in the tissue with liver for the highest; Spleen, kidney, lung, intestinal, the heart, stomach, spinal cord and brain successively decrease successively.This medicine is mainly drained from excrement.6. the Radix Salviae Miltiorrhizae aqueous solution induces gastric ulcer that obvious protective effect is arranged to reserpine; The acetic acid chronic gastric ulcer also there is the healing of promotion effect.Radix Salviae Miltiorrhizae has cytotoxicity to sarcoma cell.It is synthetic to suppress its DNA.Radix Salviae Miltiorrhizae can obviously suppress the pulmonary fibrosis due to the Bleomycin A5 hydrochloride., and lung weight, lung coefficient are obviously reduced, and the lung hydroxyproline content obviously reduces, and the pulmonary fibrosis pathological changes obviously is suppressed, and a small amount of inflammatory cell infiltration is only arranged in the lung tissue.The renal insufficiency that adenine is brought out, all can reduce blood urea nitrogen, creatinine, glomerular filtration rate, renal plasma flow, renal blood flow are significantly increased, renal function obviously improves, the discharge that can significantly increase carbamide in the urine, creatinine, sodium and Phos can obviously improve SOD activity in erythrocyte, the heart, liver, the kidney, and lipid peroxide content in remarkable reduction serum, the heart, liver, the kidney is also arranged accordingly.
Rhizoma Chuanxiong: the 1. myocardial contraction rate is strengthened, and can be accelerated heart rate; Stream in the myocardial cell there is significant inhibitory effect, reduces the ischemic myocardium protein expression and reduce the ischemic myocardial cells apoptosis.2. can suppress stream in hypoxic pulmonary vascular contractile response right ventricular hypertrophy and the vascular smooth muscle, Hypoxic Pulmonary Hypertension in Rats is had therapeutical effect.3. but coronary blood flow increasing increases body endogenous superoxide dismutase activity, reduces the malonaldehyde level, and hemorrhagic shock is had preventive and therapeutic effect, and ischemic myocardial cells nuclear calcium transport function reduction is had antagonism.4. expansible cerebrovascular reduces vascular resistance, is showing the cerebral blood flow increasing amount, can obviously suppress blood plasma thrombosis globulin behind the ischemia, and the rising of platelet factor and thromboxane has protective effect to cerebral ischemia.5. the open number of mesentery blood flow and blood capillary can be increased, chronic bulbar conjunctiva and pia mater encephali microcirculation disturbance can be improved.Platelet aggregation to generation, collagen and the thrombin induction of platelet malonaldehyde has remarkable inhibitory action, and makes the rapid depolymerization of accumulative platelet.6. but renal blood flow increasing, and remarkable diuresis is arranged; Nephritis and original position nephritis all there is certain preventive and therapeutic effect; also Rhizoma Chuanxiong or ligustrazine also there is good protective action; can strengthen the phagocytic function of mononuclear phagocyte, improve the positive percentage that lymhocyte transformation rate and acid naphthyl acetate esterase detect, also can promote the formation of erythrocyte antibody (EA).Can reduce the surface of tumor cells activity, change cancer patient's high blood coagulation state, anticancer shifts, and improves the sensitivity of tumor to radiation, alleviates radiation injury.7. can reduce progesterone content in interior prostaglandin of ovary and the blood, improve uterus progesterone receptor specific bond amount, also can prevent and treat the plain nephrotoxicity of the big enzyme of celebrating, improve the effect that acute critical pancreatitis merges injury of lung, also can promote the chondrocyte secretion anabolism factor, stimulate cellular proliferation and protein synthesis.Mainly be distributed in the abundant organ of blood flows such as liver, the heart, spleen, brain and be easy to enter the central nervous system through blood brain barrier, spleen, blood, the muscle medicine is eliminated fast.
Ramulus Cinnamomi: 1. pair staphylococcus aureus, streptococcus pneumoniae, escherichia coli, Bacillus proteus, dysentery bacterium, Bacillus typhi, the section's strain of influenza virus methylene capital and Orphan virus etc. all have certain inhibitory action.2. body temperature is descended.Its analgesic and cooling effect may with its expansion peripheral blood vessel, promote diaphoresis, analgesic relevant.Cinnamic aldehyde can make autonomic activities reduce, and strengthens the sleep effect, and can resist central excitation and prolong the death time of fainting from fear due to the strychnine and suppress audiogenic convulsion.To foot is swollen the obvious suppression effect is arranged, and arthritis is had certain preventive effect.3. can resist skin, muscle, nerve and the hemorheological pathological change of limbs fraud model of a syndrome, can remove the contraction of blood capillary, reduce plasma fibrinogen content, reduce the blood plasma viscosity, help the abundant exposure and the distortion activity of hemocyte surface charge, thereby whole blood viscosity is reduced, and can remove erythrocyte and platelet aggregation, improve the tissue blood circulation, eliminate the edema of sarcoplasmic reticulum and Schwann cell endoplasmic reticulum, pathological tissues is reversed repair; The myocardial nutrition blood flow is increased.4. can resist the mast cell degranulation release medium, anti-allergic effects is arranged.The cinnamic aldehyde platelet aggregation has inhibitory action and the antithrombase effect is arranged.
Radix Bupleuri: 1. can obviously suppress the sufficient edema that causes by dextran, many inflammatory processes are comprised ooze out, capillary permeability, the release that causes scorching medium, leukoplania and connective tissue proliferation etc. be all influential; The peritoneal fluid that Dichlorodiphenyl Acetate causes oozes out the obvious suppression effect.The heating that escherichia coli, typhoid fever polyvalent vaccine are caused has analgesic cooling effect.2. there is tangible motion to suppress and stable effect, can obviously prolongs the length of one's sleep that ciclobarbital soluble causes, can also the antagonism methamphetamine, metamfetamine and caffeine be to patient's excitation.Smooth muscle there is analgesic activity, stronger antitussive effect is arranged.3. can significantly reduce the serum alanine aminotransferase (ALT) of carbon tetrachloride poisoning, the effect that alleviates hepar damnification is arranged; Hepatic injury due to Typhoid Vaccine, ethanol, carbon tetrachloride, the D galactosamine etc. there is the significantly anti-effect that damages and promote bile secretion.The experimental hepatic injury due to D-galactosamine, carbon tetrachloride and the r naphthalene sulfocyanic ester be can suppress, serum aspartate aminotransferase, ALT activity significantly reduced.The excited intestinal smooth muscle of energy all has remarkable inhibitory action to ethanol ulcer, harness water logging stress ulcer and pylorus ligation ulcer.4. to hydrochloric acid-ethanol ulcer, can increase hexosamine and sialic content in mucus secretion stomach function regulating mucous membrane tissue and the gastric juice.Can recover the inhibition of cyclophosphamide or influenza virus to delayed hypersensitive reaction.Can obviously improve the activity of activated splenocyte conversion ratio of canavaline and natural killer cell.Thymus there is inhibitory action, causes body's immunity to reduce.5. the effect that reduces the hyperlipemia serum cholesterol is arranged; Can increase the formation of liver fat and cholesterol, the level of plasma cholesterol, triacylglycerol and phospholipid that reduction has been raise by cholesterol; Growth of bacillus tubercle, plasmodium, leptospira, vaccinia virus and staphylococcus aureus there is inhibitory action.Can obviously increase the protein biosynthesis of liver slice, leucine-C protein is obviously increased, can increase euglycemia; Can suppress steatolysis and suppress the nucleus formation that insulin promotes fat, make fat mass reduction in the blood.The 6 pairs of trypsin, Na+, the activity of K+-ATP enzyme has stronger inhibitory action.
Radix Platycodonis: 1. can significantly increase respiratory tract mucus secretory volume, tangible phlegm-dispelling functions is arranged.2. platycodin A, C, the D[1 in the Radix Platycodonis], the foot swelling due to D2, D3 on Carrageenan and the acetic acid has antiinflammatory action, the permeability and the granuloma induced by implantation of cotton pellets of the blood capillary that anaphylactic shock is caused are remarkable inhibitory action; And it is also effective to arthritis.The extract of Radix Platycodonis can strengthen phagocytic function, and the sterilizing power of neutrophil cell improves activity of lysozyme.3. platycodin A, C, the D[1 in the Radix Platycodonis], D2, D3 have gastric secretion, the anti-effect that consumes the gastric secretion due to voltinism ulcer and the pylorus ligation of suppressing, the chronic ulcer due to the Dichlorodiphenyl Acetate has obvious curative effects.Can reduce hind leg blood vessel and resistance coronarius, blood flow increasing.To isolated atria, contractility is weakened, decreased heart rate, but can resist the atrium inhibition that Ach causes.Four itch pyrimidine diabetes and food blood glucose are descended.Can suppress voluntary activity, prolong the length of one's sleep of ciclobarbital soluble, present tangible sedation; Dichlorodiphenyl Acetate writhing response and tail platen press are analgesic activity, and the heating to due to typhoid fever, the paratyphoid fever vaccine all has the effect of significant reduction body temperature.4. platycodin A, C, the D[1 in the Radix Platycodonis], D2, D3 can reduce the content of liver inner cholesterol, increases the drainage of steroid and cholic acid; The congested edema that ligation causes to the bilateral jugular vein has edema and diuresis, can obviously promote the growth of photosynthetic bacteria, and lixiviating solution concentration is higher, and the short fruit of coming into force is healed obviously.
Radix Achyranthis Bidentatae: 1. the writhing response of Dichlorodiphenyl Acetate has significant inhibitory effect, and the different processed product of Radix Achyranthis Bidentatae all has analgesic activity, and is wherein strong and lasting with wine Radix Achyranthis Bidentatae (processed) analgesic activity.2. radix achyranthis bidentatae saponin has significant analgesia role.Can promote the Ovum Gallus domesticus album arthroncus, formaldehyde is arthritic disappears, the human body immunity improving function, activating macrophage to phagocytic activity and blood vessel dilating, the improvement circulation of antibacterial, promote effect such as inflammatory lesion absorption.Heart there is inhibitory action, and contractility is weakened, obvious vasodilation and of short duration hypotensive effect are arranged, excited with breathing simultaneously in blood pressure drops, accelerated breathing is deepened.The Radix Achyranthis Bidentatae saponin has significant dose dependent antifertility action, can cause embryo's discharge, death or colporrhagia.Normal high low shear rate whole blood viscosity, hematocrit, erythrocyte aggregation index all there is remarkable reduction effect; The stasis syndrome model is had anticoagulation, prothrombin time and KPTT are prolonged slightly, the blood plasma recalcification time obviously prolongs.3. the contained ecdysterone of Radix Achyranthis Bidentatae has inhibitory action to hyperglycemia, promotes glucose synthetic protein and glycogen in the normal hepatocytes.Spleen index and thymus index, peritoneal macrophage are increased erythrocytic phagocytic percentage and phagocytic index, improve or reduce rosette rate.Hematid immunity function there is remarkable facilitation, improves normal radiation damage serological specificity antibody hemolysin content and increase spleen hemolysis plaque formation cell number, body fluid is had immunologic function.Can improve glutathion Peroxidase activity in the blood, reduce the content of lipid peroxide, illustrate to have function in delaying senility.4. Inokopolyose (ABP) has inhibitory action to sarcoma, hepatocarcinoma, improves the NK activity of carcinoma cell, strengthens the cytotoxicity to the low ascites cells that ends.Can increase osteoporotic mobility due to the retinoic acid, stop losing of bone mineral nitrogen that retinoic acid caused, increase content organic in the bone, improve bone density, thereby reach the osteoporotic purpose of control.
(2) QI invigorating spleen reinforcing medicine: Radix Ginseng Rubra 6, the Rhizoma Atractylodis Macrocephalae 18, Poria 20, Radix Glycyrrhizae Preparata 12, Fructus Jujubae 12;
(3) the cloudy Yuanyang medicine of complement now: Placenta Hominis 15, Colla cornus cervi 6, the Cortex Eucommiae 10, Herba Cistanches 12, Carapax et Plastrum Testudinis 30, Colla Plastri Testudinis 6, Colla Corii Asini 15, Fructus Lycii 12, Radix Rehmanniae Preparata 18;
Radix Ginseng Rubra: 1. Radix Ginseng and different preparation thereof, heterogeneity have regulating action to central nervous system's physiological function.(1), make in the Radix Ginseng of flaccid muscles, cooling, reduce effect such as voluntary activity; The hydroalcoholic extract of Radix Ginseng then has excited cerebral cortex, and the excitement of enhancing cerebral cortex is reacted with the activity of process of inhibition, strengthens the cholinergic nerve function, and makes blood pressure drops, breathing excitement.(2), to the central nervous system excited with the two-way function that suppresses, ginsenoside Rg's class has the central excitation effect, the Rb class then presents sedation.(3), rhamnose saponin B has tangible sedation; Radix Ginseng GNS has inhibition, stable, sedation to the central nervous system, raising Xi ability is arranged, obviously promote the facilitation memory impairments going down of learning behavior had preventive effect.(4), proteinic synthetic, RNA and the synthetic of DNA are all had facilitation, Panaxadiol saponin and protopanaxatriol ginsenoside are to striatum Na+, and the k+-ATP enzyme all has the obvious suppression effect.2, the ginsenoside can significantly stop cerebral ischemia and refilling process mediopellis electroencephalogram generation severe inhibition and cerebral edema to form, can accelerate to pour into again cerebral blood flow, reduce the calcium accumulation, alleviate cerebral edema, prolong under the bilateral clavicle and autonomous respiration and brain electrical acti time after the common carotid artery ligation.(1), multiple reticuloendothelial system phagocytic function is all had tangible activation, can strengthen it to colloid carbon granules, staphylococcus aureus, the erythrocytic ability of cleaning up of engulfing in the blood flow.Rg1 can increase the weight of immune organ and the phagocytic function of macrophage.The Radix Ginseng polysaccharide also has the effect that promotes the body specific immunity.The content of specific antibody IgH in the erythrocyte immune serum is obviously raise.(2), the ginsenoside has significant potentiation to the lymphocyte transformation of bacteria lipopolysaccharide and concanavalin A stimulation.Lymphproliferation response facilitation to various mitosis primary stimulis is the most obvious, and the ginsenoside has facilitation to lymphocytic spontaneous nuclear transformation.(3), the external concanavalin A that is subjected to press down of the immunity due to the Re, Rd Dichlorodiphenyl Acetate prednisolone stimulates lymphocyte transformation that tangible potentiation is arranged, and can make it return to normal level fully.(4), can strengthen lotus tumor natural killer cell activity, suppress the weight of tumor piece, the obvious hypertrophy of lotus tumor spleen, thymus obviously dwindles.And the IL-2, r-IFN level and the natural killer cell activity that make the lotus tumor recover normal.Tachycardia is corrected in the arrhythmia effect that can have stronger anti-barium chloride to bring out, and makes it recover normal.Panoxadiol's saponins is amphicheirality's effect to Wist-ar myocardial cell action potential; To myocardial ischemia be perfused with protective effect again.(5), blood pressure is reduced, can make the kidney vasoconstriction, significantly improve renal vascular resistance.And femoral artery, vertebral artery and renal artery vascular resistance are reduced.The hemorrhagic shock cardiac function is had significant protective effect, strengthen myocardial contraction, the increase of norepinephrine and DOPAMINE CONTENT IN RABBIT when Panaxadiol saponin can stop shock simultaneously suppresses the release of shock stage platelet to 5-HT.(6), erythrocyte membrane is had protective effect, also have direct stimulation CFU-E proliferation function, the mechanism of action of Radix Ginseng total saponins may be to promote bone marrow hematogenesis indirectly by the activity that strengthens hemopoietic growth factor such as erythropoietin.The effect of anticoagulant and reduction blood coagulation is arranged.The withdrawal symptom that (7), can obviously suppress morphine, the ginsenoside can block the generation of the metabolite hydromorphone of morphine effectively, improves the level of glutathion in the liver, removes the inhibition of morphine to release neurotransmitters in the brain, thereby prevent morphine toleration and addiction, alleviate withdrawal symptom.3. ginsenoside-Rb1 promotes platelet aggregation, and the ginsenoside has inhibitory action to collagen-induced gathering etc.Radix Ginseng total saponins can increase the adrenocortical hormone secretion.Growing animal uterus and ovary weight are increased; The acceleration maturation process, and prolonged sexually matured female rutting period; Quicken the growth and the ovulation of ovary.The panaxynol extract can make the antepituitary thyrotropin discharge to be increased.4. ginseng polypeptide can reduce euglycemia or hepatic glycogen, and hyperglycemia is all had inhibitory action, and can strengthen the decomposition of epinephrine to hepatic glycogen; Euglycemia and various hyperglycemia all there is the reduction effect.5. Radix Ginseng extract has inhibitory action to fatty liver and hyperlipidemia.(1) Rb2 reduces diabetes serum triacylglycerol, very low density lipoprotein (VLDL), free fatty, T-CHOL and ketoboidies, the cholesterol of high density lipoprotein raises, atherogenic index reduces, cholesterol there is disassimilation and promotes Excretion, can promote that triacylglycerol changes in the fatty tissue.To nucleic acid and the proteinic synthetic facilitation that has.Radix Ginseng component GN3 and GN4 make the active increase of dna dependent rna polymerase in the liver cell nuclear, promote the orotic acid of labelling to mix in the hepatocyte nRNA, cause the synthetic increase of rough endoplasmic reticulum film attached type polysome and secretary protein.Has antitumor action.To the hepatocarcinoma that the dimethyl butter yellow brings out, Leptoradix Ginseng's syrup can make the hepatocarcinoma incidence rate reduce, and promotes the body cell immunity, and the hepatocarcinoma that chemical carcinogens is brought out has prevention or control action.(2) glycol saponins Rb2 has very high anti-tumor activity, to tumor have that induction, propagation suppress, inducing cell transfers effect such as die.Alleviate radiation damage, promote its recovery, improve survival rate, obviously reduce the chromosome aberrations rate that X ray brings out, thereby reduce the side effect and the toxic action of antineoplastic radiation and chemotherapy.Suppress erythrocytic haemolysis and membrane lipid peroxidation, have the free radical of removing function and the erythrocytic effect of protection.Liver endochylema glutathion peroxidase and catalase activity significantly, thus the body hydrogen peroxide is removed.Function in delaying senility is arranged.Can obviously suppress the inductive gastric mucosa damage of acidic alcohol.
The Rhizoma Atractylodis Macrocephalae: 1. the flesh bar has stronger excitation at the bottom of pair stomach, can promote gastrointestinal to arrange into motion.Can obviously promote small intestinal pit cell strain cell proliferation and intestinal epithelial cell to divide a word with a hyphen at the end of a line, can also promote the IEC-6 differentiation.2. gastric ulcer there are prevention and therapeutical effect.Hepatic injury is significant protective effect.Can obviously increase bile secretion.3. can strengthen antibody and produce ability, the phagocytic function of lymhocyte transformation rate and M can promote the secretion of proliferation of bone marrow cells reaction and IL-1 and IL-2, improves peripheral blood WBC quantity, increases spleen and thymic weight, and the T lymphocyte function is also had potentiation; Can improve the activity of macrophage, enhancing body non-specific immunity, the growth of anticancer.4. expansible blood vessel is inhibitory action to heart, makes blood pressure drops; Heart muscle is had negativity muscular strength and negative chronotropic action, can obviously reduce the contractility of right atrium flesh, its heart rate simultaneously slows down; The positivity ladder-effect of left atrium flesh is reduced.5. can effectively reduce LPO content, can improve erythrocyte sod and GSH-PX activity, suppress the activity of brain monoamine oxidase, MAO, reduce MDA content in the erythrocyte,, and have the effect of the reactive oxygen free radical of removing anti-erythrocyte autoxidation haemolysis.6. sarcoma, ehrlich carcinoma and lymphosarcoma ascitic type there are inhibitory action, can strengthen the specificity active immunity of the antigenicity antibody of cancerous cell; Raising body antitumor respond reaches the cytotoxicity to oncocyte.7. can reduce the alloxan diabetes blood sugar level, can reduce the amount of drinking water and the consumption appetite of diabetics, damage has certain restitution to islets of langerhans, suppresses thymus, the islets of langerhans atrophy.8. can produce obvious and persistent diuresis, peritoneum hole average diameter and open density are being shown increase, the peritoneum hole is had stronger regulating and controlling effect.Calmness, blood coagulation resisting function are arranged, the spontaneity in unpregnancy uterus is shunk and irritability shrinks and all is inhibitory action.
Poria: 1, can prevent the generation of slight gastric ulcer, the effect of stress gastric ulcer due to the prevention of water invasion and attack is also arranged.2., hepatocyte injury and the alanine aminotransferase rising that carbon tetrachloride is caused has good prevention effect.Can suppress sarcoma and ehrlich carcinoma and leukemia, improve the level of NIN patient's in-vivo tumour necrosin of inoculation ehrlich carcinoma and natural killer cell activity 3, normal and lotus tumor patient's immunologic function is had potentiation, can strengthen macrophage phagocytic function, make the spleen antibody secreting cell count showed increased, increase lotus tumor patient ANAE positive lymphocyte number, antagonism can make leukocyte increasing quicken because of atrophy of thymus gland and the spleen that the lotus tumor causes increases.4. have to strengthen the effect of shrinking and accelerating heart rate, the contact dermatitis that staphylococcus aureus, escherichia coli, Bacillus proteus, chlorination picric acid are formed all has inhibitory action.
Radix Glycyrrhizae Preparata: 1, Radix Glycyrrhizae can suppress escherichia coli, staphylococcus aureus, Pseudomonas aeruginosa, group B streptococcus, vesicular stomatitis virus, worker's type herpes simplex virus and vaccinia virus, and clonorchis sinensis is had insecticidal action.2, can suppress adrenal gland-hypophysis cerebri s function, promote the kidney feritin to produce, have antagonism exogenous the amycin nephropathy.3. can the effect of negativity frequency and negativity conduction be arranged to arrhythmia and AF.4. the agonist-like effect that has Angiotensin II AT1 receptor.Reduce cholesterol and blood fat such as serum, liver, improve content of phospholipid, Radix Glycyrrhizae can prolong the blood plasma recalcification time, anticoagulant.Radix Glycyrrhizae suppresses Semen Ricini oiliness diarrhoea, water logging stress ulcer and hydrochloric acid ulcer; increase bile flow; can improve the discharge of secretin concentration and pancreas in the blood; suppress duodenum and jejunum contractile response that bethanechol causes; can also suppress liver fat degeneration and hepatic fibrosis, hepatic injury is had protective effect.5. can suppress that rising and pleura inflammation that granuloma induced by implantation of cotton pellets, sufficient sole of the foot Ovum Gallus domesticus album inflammation, histamine cause the capillary of skin permeability are oozed out, eosinophilic granulocyte's chemotactic and infiltration in the bronchovesicular of inflammatory cell infiltration and allergic asthma.Also can resist trachea and shrink, reduce the cough number of times, reduce the phenol red secretory volume of respiratory tract.6. middle polysaccharide can improve serum levels, reticuloendothelial system monokaryon function, strengthens the ability of lymphocytic emiocytosis.7. suppress sensitizing antibody and generate, prevent and treat anaphylactic shock.Different careless aglycon-4-celery glucoside can suppress the propagation of DU145 and LNCaP prostate gland cancer cell, the mutation of X ray, N-NSC-23909 and bone marrow cell chromosome aging.8. can reduce Semen Strychni toxicity, the cardiac toxicity that the aconitine in the antagonism Radix Aconiti Lateralis Preparata brings out improves active anticancer, reduces the cyclophosphamide toxic and side effects, and the cadmium poisoning liver damage is had protective action.9. infringement has protective effect to the tremulous pulse Focal Cerebral Ischemia Reperfusion, can improve brain mitochondria ATP enzyme, cerebral tissue lactic acid dehydrogenase activity, alleviates cerebral edema, alleviates the injury of kidney of the acute ischemia re-perfusion model of bilateral kidney.Deferent duct that antagonism norepinephrine, acetylcholine, histamine cause shrinks, and suppresses uterine contraction, and the dysmenorrhea that oxytocin etc. is brought out has analgesic activity, and Radix Glycyrrhizae can promote salpingitic immunologic function.10. the liver peroxide injury there is protective effect.Radix Glycyrrhizae can reduce diabetes erythrocyte sorbitol, increases the tyrosinase activity and the melanin content of melanoma cells, improves the internal ear auditory function.Radix Glycyrrhizae can suppress the propagation of lymphocyte and macrophage, prolongs the time-to-live of corneal graft.
Fructus Jujubae: 1. no perverse Fructus Jujubae benzyl glycosides I in the Fructus Jujubae and II, Herba Catharanthi Rosei glycosides etc. have hypnosis and the enhancing effect of sleeping soundly.2. naringenin-C-glucosides class can reduce spontaneous activity and the reflection to stimulating, and has and cause cataleptic effect.Carbon tetrachloride is caused that hepatic injury has liver protection effect.The energy weight increase prolongs swimming time.The Fructus Jujubae crude polysaccharides has tangible anticomplementary activity, and has concentration dependent.3. Fructus Jujubae and jujube polysaccharide can improve the phagocytic rate of macrophage and the phagocytic function of phagocytic index and the interior monokaryon-macrophage system of body, promote lymphocyte transformation and improve the periphery lymphocyte decomposition; Jujube polysaccharide can significantly strengthen the secretory function of M Φ to the cytotoxicity of leukemic L929 cell strain and TNF-a, IL-1, NO; Fructus Jujubae neutral polysaccharide, Fructus Jujubae crude polysaccharides, acidic polysaccharose all have the lymphopoietic effect of promotion.4. jujube polysaccharide, obvious slow down aging alleviates the aging of the atrophy of aging model immune organ and brain, improves aging model blood SOD and CAT vigor, reduces brain homogenate, liver homogenate and blood plasma LPO level, has the effect of removing free radical.5. can obviously reduce adenocarcinoma of stomach, gastrointestinal cancer incidence rate, suppress tumor.Sister's chromatid interchange (SCE) value that can obviously reduce caused by cyclophosphamide raises, and has antimutagenic effect.
Placenta Hominis: 1. Placenta Hominis can be secreted hormones such as fine hair promotion glandular hormone; Can promote the spleen lymphocyte proliferation activity, the immunologic function of improving due to the cold stress suppresses rising interleukin-22 activity; Placental villus tissues homogenate has antibacterial activity; The Placenta Hominis active factors has inhibition and direct killing effect to herpes simplex virus, and pair cell is nontoxic, promotes the cell growth; Can improve hemopoietic function, the anemia that hemorrhagic anemia and cyclophosphamide are caused all has preventive and therapeutic effect, the bone marrow depression that the antagonism cyclophosphamide causes, leukocyte increasing.2, hemopoietic function of bone marrow there is facilitation, nutritious and the somatomedin effect to new life's epidermal basal cell, can promote cell proliferation and metabolism intacellin to suppress to change into the reaction of DOPA from tyrosine, can when existing, epidermal growth factor can promote horn cell propagation by the melanic formation .3 intacellin of influence, can alleviate gangrene of skin to scalding, promote wound healing; Analgesic activity is arranged, can prolong body multiple calcium, thrombinogen and partial thromboplastin time, have anticoagulation, can suppress the isocellular growth of lung squamous adenocarcinoma, can improve the memory impairment due to Shandong hyoscyamine and the sodium nitrite.
Colla cornus cervi: can shorten the incubation period of erection, mating ability is had enhancing trend, seminal fluid capsule and prostate are had effect of gain.
The Cortex Eucommiae: 1. can cause quick and persistent hypotensive effect.Can suppress delayed hypersensitivity, antagonism T cell reduces, and T cell percentage ratio is risen, and strengthens the inhibition of small cell phagocytic function due to the peritoneal macrophage phagocytic function, antagonism hydrocortisone.2. can make eosinophilic granulocyte and lymphopenia, hepatic glycogen increases, blood sugar increasing, and atrophy of thymus gland, hydrocortisone content increases in the blood plasma, has the effect of excited hypophysis-interrenal system.3. can resist the excitation in uterus.Can reduce spontaneous activity, the erythrocyte superoxide dismutase vigor is raise, adrenal gland's weight increases, and plasma cAMP and cGMP are obviously raise; Can increase NO, reduce MDA content, improve the NOS activity, have certain anti-aging effects, have the promotion cel l proliferation.
Herba Cistanches: 1. can strengthen delayed hypersensitivity, body fluid and cellular immune function, monokaryon-macrophage phagocytic ability and macrophage phagocytic rate; Can increase weight, hemolysin and the hemolysis plaque value of spleen and thymus, improve lymhocyte transformation rate, lymphocytic amount is increased.2. can raise cAMP level in the peritoneal macrophage obviously increases antepituitary, ovary and uterus weight; Ovary human chorionic gonadotropin (HCG)/LH receptor-specific adhesion obviously improves; Have antagonism suspention stress load due to male sexual function and the low effect of learning behavior; Can increase hypothalamus norepinephrine and 5-hydroxyindoleacetic acid content, and increase dopamine and dihydroxyphenyl acetic acid ratio, striatum is had certain increase effect.3. can improve the erythrocyte superoxide dismutase activity, and reduce the content of lipofuscin in the cardiac muscular tissue; Prolong the dead order number of average life, maximum life span and half, delaying decrepitude of skin, enhancing human body immunity function, rising erythrocyte membrane enzymatic activity; Can improve the intestinal propulsion degree, shorten the relieving constipation time, can effectively resist the effect that atropine suppresses defecation and big intestinal absorption moisture; Can suppress atherosclerosis, the degeneration propagation of smooth muscle cell is improved its Change of Ultrastructure, reduces smooth muscle cell endoperoxides lipid content, improves its SOD activity.4. increase and irritate the back coronary flow again, reduce coronary resistance, promote the recovery of myocardial contraction, and obviously alleviate the myocardial ultrastructure damage.
Carapax et Plastrum Testudinis: 1. reduce the content of T3, T4 in the hyperthyroidism serum, erythrocyte membrane Na+, K+ ,-atpase activity, cAMP in plasma and blood plasma viscosity and whole oxygen consumption, and make blood sugar increasing, improve the threshold of pain, decreased heart rate; The thyroid of atrophy recovers growth, and amount of drinking water reduces, thereby increases urine amount, weight increase.2. Carapax et Plastrum Testudinis has the thyroid function of the animal that reduces hyperthyroidism; Colla Plastri Testudinis can impel peritoneal macrophage quantity to increase, and volume increases, and pseudopodium increases, and improves cellular immunization and humoral immune function; Can make adrenal cortex recover growth, the cortex glomerular zone thickens, and zona fasciculata unit are cell number reduces, and can reduce the adrenal cortex function of hyperthyroidism type animal effectively.3. the uterus there is tangible excitation; Serum copper and copper/zinc ratio is descended; Can promote the growing multiplication of human embryonic lung diploid fibroblast (2Bs cell), show that pair cell has function in delaying senility; Can reduce the urinary hydroxyproline excretion, bone density improving and bone calcium, content of magnesium, and make Serum alkaline phosphatase activity that rising trend be arranged.Carapax et Plastrum Testudinis to focal cerebral ischemia after neural stem cell the promotion proliferation function is arranged, can alleviate the nerve injury symptom.
Colla Plastri Testudinis: Colla Plastri Testudinis is leukocyte increasing quantity obviously, and anemia is had blood tonification effect, increases the RBC and the Hb of anemia; The effect of thrombocytosis is arranged, shorten the bleeding time; Can also strengthen the reticuloendothelial system phagocytic function,
Colla Corii Asini: 1. RBC number, hemoglobin and the leukocyte count of raising arranged, promote the effect of hemopoietic function.2. the Antiradiation injury effect is arranged, blood hemoglobin, leukocyte count and bone marrow nucleated cell number are obviously increased.3. can improve the phagocytic activity of peritoneal macrophage, increase the immunologic opsonin rosette forming cell and the specificity Flos Rosae Rugosae rate of spleen.4. liver, spleen mononuclear phagocyte there are facilitation, natural killer cell activity are being shown strengthen, the healthy human lymphocyte transformation of promotion is arranged.5. can improve hypoxia-bearing capability, strengthen the cold resistant ability, and the antifatigue effect in the swimming.6. can promote coagulation process, clotting time be shortened play anastalsis.Can increase the people's amount of taking the photograph of calcium in the body, improve the bone calcium that causes because of calcium deficiency effectively and lose, calcium salt outflow, osteoporosis and hyperosteogeny and all kinds of fracture.7. can make the very fast recovery of blood pressure, the blood pressure drops that endotoxin is caused, the cloudy power of total periphery raises, and blood viscosity rises and the bulbar Conjunctiva Microcirculation obstacle alleviates or recover normal as early as possible.8. have the effect that the rational vascular permeability of enantiopathy increases, help microcirculatory blood perfusion and recover normal, the hematodinamics situation is improved.
Fructus Lycii: 1. the lycium barbarum polysaccharide in the Fructus Lycii (LBP) is inhibitory action to T, the bone-marrow-derived lymphocyte factor, little to 10-be accretion during 5mg/ml, macrophage C and Fe acceptor quantity and vigor can be increased significantly, and the inhibitory action of hydrocortisone acetate can be weakened macrophage C and Fc receptor.2. can improve the lymphocytic propagation function of splenic T, strengthen the killing ability of cytotoxic T cell (CTL), can resist cyclophosphamide (CY) to the T lymphocyte, the immunosuppressive action of CTL and natural killer cell (NK cell) also has tangible anti-X-radiation effect.3.LBP can significantly promote splenocyte propagation, delaying senility function is arranged.The inductive mutant TA98 of carcinogen, TA100 there are the mutation inhibiting effect, antimutagen are arranged and have and resist, block mutagenic action.4. people's adenocarcinoma of stomach KATO-III cell is had obvious inhibitory action, its mechanism of action shows that mainly suppressing cell DNA synthesizes, the interference cell division, and cell is grown ability drop again.5. the effect of serum total cholesterol (TC) in the obvious reduction blood, triacylglycerol (TG), low-density lipoprotein cholesterol (LDL-C) and the effect that reduces TC, TG in the liver are arranged; The hepatic injury that carbon tetrachloride is caused has inhibition fat to deposit and promote hepatocyte new life's effect in hepatocyte, and the carbon tetrachloride poisoning hepatitis is had the protection effect.6.LBP normal hemopoietic function is had facilitation, can make leukocytosis; Can promote splenic T lymphocytic emiocytosis colony stimulating factor, improve serum colony stimulating activity level.Can reduce the heart, brain, skeletal muscle tissue mitochondrial DNA deletion, improve synthetic and the heart, skeletal muscle mitochondrial respiratory chain compound enzyme IV vigor and the brain mitochondria respiratory chain compound enzyme I vigor of the heart, brain mitochondria adenosine triphosphate (ATP); Ametycin is brought out the antagonism of micronucleus, find that Fructus Lycii has tangible anti-ametycin and brings out the micronucleus effect.7. lycium barbarum polysaccharide (LBP) can make blood glucose obviously reduce, and the hyperglycemia level also obviously reduces.The effect of bringing high blood pressure down reduces the high blood systole of kidney, diastolic blood pressure, reduces malonaldehyde in blood plasma and the blood vessel, and content of ET increases the release of calcitonin-gene-related peptide.To staphylococcus aureus, staphylococcus epidermidis, micrococcus lysodeikticus bacterium, Bacillus typhi H-901, Bacillus typhi O-901, paratyphoid bacillus A, Bacillus paratyphosus B, Bacillus paratyphosus C, Bacillus typhi, dysentery bacterium, escherichia coli, aerobacteria, Pseudomonas aeruginosa, bacillus subtilis, anthrax bacillus (avirulent strain), epidemic disease bacillus (avirulent strain), read 17 kinds of antibacterials such as coccus in vain stronger inhibitory action all arranged.9. can promote the growth of lactobacillus, and stimulate it to produce acid; Can make skin hydroxyproline content increase by 15.5%, can significantly strengthen hypoxia-bearing capability, can the significant prolongation swimming time.
Radix Rehmanniae Preparata: 1. can promote to be growth, the anemia animal erythrocyte of CFU-GM, the recovery of hemoglobin, accelerate pluripotential hemopoietic stem cell, bone marrow hemopoietic progenitor cell of red blood cell line propagation, differentiation is arranged.Can significantly suppress liver hemorrhagic necrosis kitchen range and simple necrosis.2. the macrophage function of Dui Shou Damage has protective effect.3. significant hypotensive effect is arranged, can improve symptoms such as insomnia that hypertension causes, headache, dizziness, numb hand and foot, and heart rate is had certain influence.Can strengthen the activity of glutathion peroxidase, lipid peroxide is reduced.Amount of drinking water and urine amount can be improved, blood plasma T3, thyroxine (T4) and aldosterone (AD) concentration and deficiency of YIN symptom can be improved, and the thyroxin state of energy dysregulation.4. the mitotic effect of the epithelial cell of inhibition is arranged, liver, the proteinic decomposition rate of nephridial tissue are had reduction in various degree, and the lung tissue protein synthesis rate is increased to some extent.
(4) the lung moistening nourishing YIN medicine that promotes the production of body fluid: Radix Asparagi 12, Radix Ophiopogonis 12, the Radix Rehmanniae 12.
(5) turn over fiery intercalation intestinal charthartic: Cortex Phellodendri 10, Semen Armeniacae Amarum 12.
(6) spleen reinforcing is good for the stomach, aid digestion absorption medicine: Fructus Hordei Germinatus 20, Fructus Setariae Germinatus 20, burnt short, bristly hair or beard 18, Massa Medicata Fermentata 18, Semen Raphani 12, chicken gold 10;
(7) Town that calms the nerves is quiet, reinforcing the heart blood-nourishing drugs: Arillus Longan 18, Semen Ziziphi Spinosae 20, Radix Polygalae 10.
(8) endogenous wind stopping that reduces phlegm is Dinged the Jing Qin heart, the nootropics of calming the nerves: Calculus Bovis 0.6, pig sand 0.3;
Radix Asparagi: 1. after the Radix Asparagi decoct dilutes, to anthrax bacillus 206, first type and beta hemolytic streptococcus, diphtheria corynebacterium, diphtheroid, streptococcus pneumoniae, staphylococcus aureus, Staphylococcus citreus.Staphylococcus albus and bacillus subtilis have inhibitory action in various degree.2. Radix Asparagi polysaccharide can suppress the tumor necrosis factor of alcohol-induced, can suppress sarcoma, and central inhibitory action is also arranged, and can significantly prolong the silk ribbon attached to an official seal or a medal aging.
Radix Ophiopogonis: 1. can improve the cardiac hemodynamics effect, improve positive inotropic and heart pump function; The myocardial contraction that can strengthen heart strengthens, and coronary flow increases, and heavy dose then suppresses cardiac muscle, reduces coronary flow.2. can alleviate the myocardial cell anoxia infringement of long-time swimming back, dwindle the effect of infarction size and necrotic zone.Can prevent or resist by chloroform-epinephrine, barium chloride, the inductive arrhythmia of aconitine, and the ventricular arrhythmia incidence rate behind the ligation arteria coronaria 24h is reduced.3. can improve the hypoxia-bearing capability under the hypobaric hypoxia condition, prolong the time-to-live of normobaric hypoxia.4. can increase spleen weight, significantly increase the carbon clearance effect, stimulate the generation of hemolysin in the serum, the antagonism leukocyte count descends, and strengthens the red cell agglutination rate.5. blood glucose is descended, impel B cell to recover the original increase trend of glycogen.Stimulating the human polymorphonuclear leukocyte to breathe to carcinogenic promoting agent PMA breaks out the generation reactive oxygen free radical, very strong scavenging action is arranged; Can reduce hydroxyproline in the body, suppress monoamine oxidase, MAO (MAO-B) in the brain, and make the active raising of superoxide dismutase (SOD).Obvious life-saving, superoxide dismutase activity improving, serum Total antioxidant capacity and hematid immunity function reduce the serum mda content, have function in delaying senility.6. can obviously suppress normal gastrointestinal propulsion, and inhibitory action increases with the increase of dosage; Contraction has antagonism to the tetanic property of intestinal smooth muscle.Staphylococcus albus, bacillus subtilis, escherichia coli and Bacillus typhi etc. there is inhibitory action.
The Radix Rehmanniae: 1. can suppress immunity Flos Rosae Rugosae formation cell in the spleen, promote activatory splenocyte DNA of con A and proteinic biosynthesis, strengthen interleukin-2 and produce, and can improve the phagocytosis of macrophages of the inductive immunocompromised of acetic acid Ni Songlong.2. making increases kidney beta receptor maximum binding capacity and returns to normally, can resist the decline of the plasma corticosterone concentration that dexamethasone causes, prevents the adrenal cortex atrophy, but cortex hypofunction on hypophysis-kidney that the part antagonist hormonal causes.3. antagonism cruor time extending strengthens the spleen lymphocyte expression of ALP ability of the class yin deficiency syndrome that thyroxine causes, and accelerates propagation, the differentiation of pluripotential hemopoietic stem cell (CFU-S), bone marrow hemopoietic progenitor cell of red blood cell line (CFU-E).
Cortex Phellodendri: 1. pair golden yellow, white and Staphylococcus citreus, Hemolytic streptococcus, streptococcus pneumoniae, anthrax bacillus, diphtheria corynebacterium, bacillus subtilis, escherichia coli, Pseudomonas aeruginosa, typhoid fever and Salmonella paratyphi, meningococcus and vibrio cholera etc. all have inhibitory action in various degree.2. certain antipyretic effect is arranged, Institute of Micro-biology is infected the heating cause, eliminate the cause of disease causes bringing down a fever except that having antibacterial action, the refrigeration function that also has with itself is relevant on the other hand.3. contained little folds in a garment alkali can resist the diarrhoea that Oleum Ricini or Folium Sennae cause, influences normal gastrointestinal China ink antiperspirant propulsion functions, illustrates to have tangible diarrhea and antiinflammatory action; Can suppress increased capillary permeability, auricular concha swelling, the intestinal secretion that antagonism vibrio cholera and colitoxin cause is hyperfunction, diarrhoea and dead.Act on the strongest product of giving birth to, it is the most weak to fry product.4. the little folds in a garment alkali of Cortex Phellodendri ingredient, phellodendrine and palmatine have hypotensive effect, can increase the booster reaction of epinephrine and norepinephrine, suppress manually to suffocate and vagus nerve stimulation to the booster reaction of middle-end, suppress to stimulate preganglionic fibre and the instant embrane that causes shrinks.5. can be excited myocardium, strengthen its contractility, have positive inotropic action, and effect takes place very fast.Can suppress cardiac muscle, its contractility is weakened; Low dose of folds in a garment alkali can strengthen the effect of acetylcholine, and heavy dose is then resisted it; Heart rate is accelerated earlier, continued later on to slow down, and increase with dosage, decreased heart rate is more remarkable; Right atrium is shown as the concentration dependent frequency effect.6. can strengthen the contraction of intestinal tube, shrinkage amplitude is increased; Obacunone then can make tension force and amplitude all strengthen, and obakulactone then makes intestinal tube relax.7. ulcer there is remarkable inhibitory action, can suppresses pepsic activity, can also obviously reduce total acidity gastric juice.Cortex Phellodendri and therefrom isolated limonin and obacunone can curtail sleep; Phellodendrine also has inhibitory action to nervus centralis, can weaken spontaneous activity and various reflection.8. platelet aggregation and the ATP release that ADP, arachidonic acid (AA), collagen and calcium ion carrier A 23187 are brought out all has inhibitory action, wherein with the strongest to the inhibitory action of collagen-induced gathering and release; Can resist the contraction of being rich in the platelet plasma clot.
Semen Armeniacae Amarum: 1. can be sedation to respiratory center, promote the synthetic of pulmonary surfactant, and pathological changes is improved.2. functions of loosening bowel relieving constipation is arranged, can suppress pepsic activity, can suppress the rising of serum aspartate aminotransferase, serum alanine aminotransferase level and hydroxyproline content.3. antitumaous effect is arranged, can improve 1 Collagen Type VI enzymatic activity of people's renal secretion, suppress people's tire kidney fibroblast proliferation and 1 Collagen Type VI and express, promote apoptosis.Tangible antiinflammatory and analgesic activity are arranged.4. can former propagation and the conversion of mitosis promoting breed spleen lymphocyte, and the NK cell activity.
Fructus Hordei Germinatus, Fructus Setariae Germinatus: 1. blood glucose is reduced and energy lactogenic and but breast.The damage of cell membrane albumen and DNA has significant protective effect, reduces the oxidation of memebrane protein and the formation of cell DNA fragmentation.2. effectively protect the oxidative damage of active oxygen, keep the normal physiological function of cell neurocyte.Can strengthen the nervous and motion in uterus, and increase with the increase of dosage.And can make it expansion; Can show the increase that reduces its serum cholesterol and triacylglycerol and lipid peroxide content, also have antifungic action.
Burnt short, bristly hair or beard: 1. can promote the stomachial secretion digestive enzyme, wherein lipase can facilitating digestion fat.Gastrointestinal function is had certain regulating action, hyperactive duodenum smooth muscle is inhibitory action, and lax pipe smooth muscle is had slight enhancing contraction.2. Crataegolic acid has the dancing effect of recovery to tired asystole, can play persistent coronary artery dilating effect, strengthens the heartbeat ability, and the myocardial damage that isoproterenol is caused has the certain protection effect; The arrhythmia that pituitrin is caused has certain inhibitory action, and the triterpenic acid in the Fructus Crataegi, Fructus Crataegi flavone etc. have hypotensive effect.3. flavonoid such as chlorogenic acid is to the cholesterol synthase vigor in the Fructus Crataegi, and serum total cholesterol, low-density lipoprotein-cholesterol and apolipoprotein B concentration have inhibitory action, can significantly reduce liver low density lipoprotein receptor mRNA level.4. Flavonoid substances such as Fructus Crataegi and Fructus Crataegi Quercetin can significantly reduce serum and liver mda content, strengthens the activity of erythrocyte and liver superoxide dismutase.Strengthen the whole blood glutathione reductase activity simultaneously.Can increase the cell percentage of thymus and spleen weight, T lymhocyte transformation rate, T lymphocyte ANAE (+) (acid a-acetic acid how lipase); Erythrocyte C3b receptor rosette rate and erythrocyte immune complex rosette rate all had obviously increase effect, the pair cell immunity has facilitation with erythrocyte immune.Can eliminate the synthetic nitrosamine of precursor substance blocking-up of synthetic nitrosamine; Mutagenic action to aflatoxin B1 has remarkable inhibition effect, can prevent hepatocarcinoma.
Massa Medicata Fermentata: contain volume yeast and vitamin B group, but appetite stimulator is kept the normal stool function.
Semen Raphani: 1. pair staphylococcus and escherichia coli have remarkable inhibitory action.2. have significant hypotensive effect, tremulous pulse and mean pulmonary arterial pressure, body blood vessel and pulmonary vascular resistance are obviously descended, the pulsatility index of left ventricle and right ventricle obviously reduces.3. effect that strengthens the contraction of the ileum rhythm and pace of moving things and the effect that suppresses gastric emptying are arranged, the effect that improves stomachus pyloricus ring muscle tonicity and reduce stomach bottom longitudinal muscle tonicity is arranged, the obvious inhibitory action that antiadrenergic drug is shunk the ileum rhythmicity.4. certain antitussive, phlegm-dispelling functions are arranged.Can also treat human serum liver sterin and raise, prevent coronary atherosclerosis.
The chicken gold: 1. pair gastrointestinal motility is inhibitory action, and pancreatic secretion is had facilitation, can strengthen protease, pancreatic lipase activity.2. have certain effect to quickening to get rid of radiostrontium.Anticoagulant is arranged and improve hemorheological effect, can alleviate the atherosclerosis degree.
Arillus Longan: 1. can reduce prolactin antagonist in the blood plasma, estradiol, testosterone content, improve progesterone, short follicle stimulating hormone content, can influence the endocrine function of hypophysis-gonad axis.2. the mutagenic action that ametycin is caused has antagonistic effect.Can suppress the liver homogenate lipid peroxide and generate T cell recall rate in glutathione peroxidase activity and thymus, the lymphoid tissue in the blood that to raise; But anxiety has the analgesic activity of sleeping peacefully.
Rhizoma Acori Graminei: Rhizoma Acori Graminei B asaricin has inhibitory action to the animal brain electricity, and main effect is a tranquillizing and allaying excitement; A asarone in the Rhizoma Acori Graminei extraction volatile oil has good epilepsy anticonvulsant action, can make righting reflex, and pain reflex and auditory reflex disappear; Asaricin energy memory reinforcing in the total volatile oil can make drug induced memory loss improve; Can suppress tracheospasm and shrink, can treat by aconitine the arrhythmia that epinephrine and chlorination shellfish are brought out; Can kill ascarid and ascites cells.
Radix Polygalae: can resist five methylene tetrachloros and sit the convulsions that causes, collaborative syngignoscism be arranged with barbital; The Radix Polygalae soap is sweet to make blood pressure drops 40% to 70%, destroys erythrocyte membrane and strong haemolysis is arranged but the Radix Polygalae soap is sweet, so the consumption of Radix Polygalae generally is no more than 10g; Radix Polygalae can make trained reflex and unconditioned reflex all increase, coenzyme, Hippocampus in the diencephalon, and coenzyme, reduced coenzyme concentration in tail antinucleus and the brain stem all increase, and show that Radix Polygalae has the effect that promotes muscle power and intelligence; The TA98 bacterial strain is returned the change clump count inhibitory action, and antimutagenic effect is arranged; SOD in the erythrocyte, hepatic tissue activity of glutathione peroxidase are raise, and showing has anti-aging effects. and the sweet A of the soap of Radix Polygalae and B, 3D, 2D and 3C have cough-suppressing phlegm-dispelling functions.Radix Polygalae and Rhizoma Acori Graminei are share, and have strengthened Town Jing'an god, the effect of hypnosis anticonvulsant, make people's mind more clear-headed, and health is more strong, and intelligence is more filled pendant, and Rhizoma Acori Graminei that the traditional Chinese medical science that Here it is is said and Radix Polygalae restoring normal coordination between the heart and kidney effect De Now are for medicine principle.
Os Draconis: 1. enhance immunity is arranged and promote the damaged tissue repair, can obviously increase the relative weight of thymus and spleen, strengthen the phagocytic activity of mononuclear phagocyte, climb the leakage foot rate of net after the minimizing injury of sciatic nerve to the serum carbon granules.2, can increase the hypnosis rate, have certain sedation.
Calculus Bovis: 1. activity is reduced gradually, motionless until peace and quiet; Calculus Bovis can suppress autonomic activities, reduce the effect of coordination exercise; Can work in coordination with pentobarbital sodium to the subliminal hypnosis effect; The length of one's sleep due to the prolongation pentobarbital sodium.2. can resist the convulsions that caffeine, cocaine cause, and alleviate the convulsions due to Camphora, the cocculin.Heating due to Typhoid-Paratyphoid first, the second triple vaccine there is very fast and strong refrigeration function; To the heating that the young beer yeast causes, tangible refrigeration function is arranged.3. remarkable and persistent hypotensive effect is arranged, can suppress the minimizing of cardiac frequency, suppress thrombocytopenia, prevent the formation of hemorrhagic necrosis focus.4. thrombosis death due to ADP and the collagen epinephrine complex liquid there is the obvious suppression effect; Can significantly resist myocardial ischemia and damage that different third adrenal gland brings out; Reduce it to induced myocardial injury.5. to the two-ways regulation of stream in the cardiac muscle, play the antiarrhythmic important function.6. taurine has the blood fat reducing cholesterol, increases high density lipoprotein, prevents atherosclerotic effect.Cholic acid is the equal sphincter muscle of bile duct that can relax of deoxycholic acid especially, thereby has choleretic effect.This two classes material forms the orthofunction system of bile excretion in body.7. the hepatic injury due to the carbon tetrachloride is had protective effect, the alanine aminotransferase that suppresses to cause thus raises.8. hepatocyte there is significant protective effect, smooth muscle is had the spasmolytic effect.The uterotonic effect of enhancing is arranged.9. to ear's inflammation due to Oleum Tiglii or the dimethylbenzene, capillary of skin permeability, granuloma induced by implantation of cotton pellets hypertrophy, formaldehyde or Ovum Gallus domesticus album pedal swelling all there is significant inhibitory effect.10. cholic acid and deoxycholic acid all have excited the breathing and the eliminating phlegm and relieving cough effect; Encephalitis b A2 virus there is direct deactivation.11. can obviously improve the quantity of antibody-producting cell in the immune spleen cell and the ability that antibody produces, can obviously improve the lymphocyte transformation effect that lipopolysaccharide stimulates.Clean up speed 12. can significantly reduce its carbon granule, suppress the peritoneal macrophage phagocytic function, suppress delayed hypersensitivity and hemolysin and form, also can obviously alleviate thymic weight.
Cinnabaris: 1. can make the time lengthening of sleeping soundly.Behind the trimester of pregnancy clothes Cinnabaris, hydrargyrum can enter in the fetus body by placental barrier, and the mercury content of fetus is increased.2. the year total nitrogen that urine is discharged increases weight increase; Can kill skin bacterium and parasite.3, Cinnabaris has antiarrhythmic effect.Distribution is in various degree all arranged, and the increase of medicining times in the heart, kidney,liver,spleen, brain, little cerebral tissue, mercury content increases gradually in the tissue, and especially kidney, liver content are the highest.So should be specifically noted that the consumption and the medication number of times of Cinnabaris.
According to foregoing, Rhizoma Cyperi, Radix Curcumae, Fructus Citri Sarcodactylis, the Radix Aucklandiae, Lignum Aquilariae Resinatum, Fructus Aurantii all have risings such as the acetylcholine that causes because of the stagnation of QI, histamine, cause vascular smooth muscles contraction, spasm such as gastrointestinal, tracheal smooth muscle or liver, brain, breast abdomen that timely spasmolysis is arranged; The tension force of alleviating gastrointestinal and gallbladder rapidly increases, and reduces gastric antrum circular muscle contraction wave mean amplitude of tide; Energy is removed because of the pituitrin of stagnation of QI increase and epinephrine etc., and removes myocardial ischemia, and arrhythmia increases the heart coronary flow and improves hypoxia-bearing capability, the effect that heart tonifying and decreased heart rate is arranged and bring high blood pressure down; And secretion and the choleretic effect that promotes somatostatin arranged, and suppress the synthetic of carbon monoxide, writhing response is reduced and the response time prolongation of shouting, showing has analgesic activity; Spontaneous activity is reduced, slow, eliminate the effect that conditionality is avoided reflection, the effect that prolongs sleep, suppresses nervus centralis is arranged; The erythrocytic aggregation of reduction is arranged, and ability is sticked in raising erythrocyte deformability and antioxidation, immunity, keeps normal blood viscosity, improves the rheological characteristic of blood, thereby has improved the erythrocytic life-span; Tangible choleretic effect is all arranged.These effects are to remove because of the long-term angry abdominal pain that causes qi depression to blood stasis painfully, and rib uncomfortable in chest expands, feeling of fullness in the head giddy, emaciation and sallow complexion or show as the emotion gloom, the modern medicine basis of symptom such as mind is dull, likes quiet happiness and sleeps, and skin is black dull.Fructus Aurantii, Lignum Aquilariae Resinatum can also make gastrointestinal motility that significant inhibitory effect is arranged, contractility is reduced, tonicity descends, can change the peak electrical activity of jejunum, ileum, shrink mutually the position that strengthens small intestinal, advances the emptying of small intestinal, increase bowel movement number of times and stool amount, play the effect of timely eliminating vivotoxin, and significantly reduce alkali phosphatase, acid phosphatase, r-glutamyl transpeptidase, and the protein level that can raise and reduce.The Fructus Aurantii that Chinese medicine that Here it is is thought, Lignum Aquilariae Resinatum have the modern medicine basis of sending down the abnormal ascending QI effect.
Drug for invigorating blood circulation and eliminating stasis can make vascular smooth muscle shrink the vascular tone that keeps certain, reaches angiectatic effect, to increase the blood flow of cardiovascular, femoral artery, cerebral arteries, blood capillary; Hypotensive effect is in various degree arranged, therefore can improve the peripheral circulation obstacle, blood flow is quickened, the open number of blood capillary increases and the hemocyte aggregation extent alleviates; Shorten thrombosis length and weight reduction, and can obviously prolong the thrombotic time; Platelet count is reduced, suppress aggregation capability, prothrombin time and KPTT are prolonged.Because of function will prevent to reduce pressure anoxia, the neuronic degeneration of ischemia hindbrain are arranged as above, brain there is powerful protectiveness; The metabolism wadding that can alleviate monoamine class neurotransmitter in the cerebral tissue is random, makes the nervousness of decline recover normal; As above effect can be accelerated the blood circulation of cerebral tissue, improve neuronic metabolism, remove middle cerebral artery thromboembolism cerebral infarction area, nerve growth and generation associated restoration albumen behind the promotion cerebral ischemia, promote nerve cell adhesion molecule and the expression that promotes the blood capillary associated protein, reduce apoptotic generation; Make how nutritious blood to brain, spinal cord, play the effect of memory reinforcing, ability to work and life-saving.For the appearance that prevents that drug for invigorating blood circulation and eliminating stasis from causing bleeding etc., prevent that blood pressure drops from containing very much, total peripheral resistance is too low, and blood viscosity is too low, for the effect that prevents a blood circulation promoting and blood stasis dispelling left side too, so this side promotes coagulation process with Colla Corii Asini, clotting time is suitably shortened, play a part Dao anti-hemorrhage, also can make blood pressure very fast extensive heavy to normal level, and can increase by disease-resistant rational vascular permeability, make hematodinamics and blood perfusion keep normal level, play the effect of two-way accent knot.
This can increase coronary flow, reduces the myocardial contraction amplitude, guarantees cardiac muscle, kidney, law during ischemia not damaged, can reduce hyperlipidemia, hyperglycemia, and study of anti-atherogenic effect is arranged.Can reduce collagen content; cure lung; hepatic fibrosis; increase the solid row amount of rushing down in the bile; to kidney; pancreas; lung; the heart; stomach has protective effect; each internal organs of whole human body there is ideal defying age effect; energy antagonism radiation damage chromosome aberrations rate; can protection be subjected to according to bone marrow and spleen hemopoietic function; have and improve the effect that nerve metabolism promotes neuranagenesis; reconcile excited and the equilibrated effect of inhibition; can reduce the cicatrix fibrosis; multiple tumor and HIV (human immunodeficiency virus) there are inhibitory action and therapeutical effect; keep normotensive effect; to cerebral ischemia; cerebral infarction has therapeutical effect; the anoxybiotic rise time can be prolonged; can reduce serum; the heart; liver; kidney; lipid peroxide content in the brain; irritation cell increases matter and protein synthesis; to tens of kinds of bacterial viruses; fungus all has inhibition or killing action; can prevent and treat multiple catching; platelet aggregation there are inhibitory action and blood coagulation resisting function, there is comprehensive benefiting action at each position of human body; preventive effect; therapeutical effect and satisfied antiinflammatory action is arranged and two coordinative roles is so played rejuvenescent effect.
, can draw rejuvenescent Ke and cut principle to rejuvenescent medicine comprehensive function from slow down aging Kao Indeed:
1. can improve glutathion Peroxidase activity in the blood, reduce the content of lipid peroxide, illustrate to have function in delaying senility.
2. from increasing osteoporotic mobility due to the dimension first, stop the bone loss that formic acid caused, increase content organic in the bone, improve bone density, thereby reach the purpose of preventing bone rarefaction.
3. can activate liver endochylema glutathion peroxidase and catalase activity, thereby the body hydrogen peroxide is removed, function in delaying senility is arranged.
4. polysaccharide can alleviate the atrophy of aging model immunity organ pipe and wearing out of brain, improves aging model blood SOD and CAT vigor, reduces brain even oar, liver homogenate and plasma C PO level, has the effect of removing from oil base, obviously slow down aging.
5. can secrete fine hair and promote hormones such as glandular hormone; Can promote the spleen lymphocyte proliferation activity, the immunologic function of improving due to the cold stress suppresses rising interleukin-22 activity; Placental villus tissues homogenate has antibacterial activity; Can improve hemopoietic function, the anemia that hemorrhagic anemia and cyclophosphamide are caused all has preventive and therapeutic effect, the bone marrow depression that the antagonism cyclophosphamide causes, leukocyte increasing, hemopoietic function of bone marrow there is facilitation, nutritious and the somatomedin effect to new life's epidermal basal cell, can promote cell proliferation and metabolism, intacellin suppresses to change into from tyrosine the reaction of DOPA, can influence melanic formation, intacellin can promote horn cell propagation when epidermal growth factor exists, can alleviate gangrene of skin to scalding, and promotes wound healing; Analgesic activity is arranged, can prolong thrombinogen and partial thromboplastin time, have anticoagulation, can suppress the growth of multiple cancerous cell such as lung squamous adenocarcinoma, can improve by the memory impairment due to scopolamine and the sodium nitrite; Promote whole body normal cell new life and existing rejuvenation effect.
6. blood plasma CAMP and GMP are obviously raise; Can increase NO, reduce MDA content, improve the NOS activity, promote cell proliferation and have anti-aging effects, play the rejuvenation effect in conjunction with various effects.
7. can increase Qiu's brain norepinephrine and 5-hydroxyindoleacetic acid content down, and increase crust amine and dihydroxyphenyl acetic acid ratio, striatum there is the matter of increasing effect, can improve the erythrocyte superoxide dismutase activity, and reduce the content of lipid in the cardiac muscular tissue, thereby can prolong average life, delaying decrepitude of skin, the enhancing human body immunity function, rising erythrocyte membrane enzymatic activity reaches the more purpose of high life.
8. serum copper and copper/zinc are descended than matter, can promote to cultivate the growing multiplication that people's lung two letter bodies become dimension cell (ZBS cell), show that pair cell has function in delaying senility, can reduce the urinary hydroxyproline excretion, bone density improving and bone calcium, content of magnesium, and Serum alkaline phosphatase activity is raise, the focal cerebral ischemia neural stem cell there is the promotion proliferation function, thereby the rejuvenation effect occurs.
9. can significantly promote splenocyte to increase matter, delaying senility function is arranged.Can promote splenic T lymphocytic emiocytosis colony stimulating factor, improve serum colony stimulating activity level, can reduce the heart, brain, skeletal muscle tissue mitochondrial DNA deletion, improve synthetic and the heart, skeletal muscle mitochondrial respiratory compound enzyme IV vigor and the brain mitochondria respiratory chain compound enzyme vigor of the heart, brain mitochondria adenosine triphosphate (ATP), the antagonism ametycin brings out the micronucleus effect, and plays the new life's effect to the heart, brain, skeleton.Can promote the growth of lactobacillus, and stimulate it to produce acid,, can make skin hydroxyproline content increase by 60%, can significantly strengthen hypoxia-bearing capability and present the merit of rejuvenation in conjunction with the effect of other drug.
10. can promote to be growth, the anemia animal erythrocyte of CFU-GM, the recovery of hemoglobin, accelerate pluripotential hemopoietic stem cell, bone marrow hemopoietic progenitor cell of red blood cell line propagation, differentiation is arranged.Can significantly suppress liver hemorrhagic necrosis kitchen range and simple necrosis.The macrophage function that suppressed by carrageenin is had significant protective effect, and antagonist forms cell inhibitory action, plays the effect of two-way accent knot.Significant hypotensive effect is arranged, can improve symptoms such as insomnia that hypertension causes, headache, dizziness, numb hand and foot, and heart rate is had irregular accent knot to normal effect.Can strengthen the activity of glutathion peroxidase, lipid peroxide is reduced.Can improve amount of drinking water and urine amount, blood plasma T3, thyroxine (T4) and aldosterone (AD) concentration and deficiency of YIN symptom, and the thyroxine state of energy dysregulation.The mitotic effect of the epithelial cell of inhibition is arranged, liver, the proteinic decomposition rate of nephridial tissue are had reduction in various degree, and the lung tissue protein synthesis rate is increased to some extent, and play the rejuvenation effect.
11. energy superoxide dismutase activity improving, serum Total antioxidant capacity and hematid immunity function reduce the serum mda content, have function in delaying senility, in conjunction with the effect of each side, can play rejuvenescent effect.
12. can accelerate pluripotential hemopoietic stem cell, bone marrow yarn erythrocyte hemopoietic progenitor cell (CFU-E) increase matter, differentiation, and guarantee latent fixed hemopoietic function.
13. SOD in the red blood cell aging, hepatic tissue activity of glutathione peroxidase are obviously raise, have anti-aging effects.
14. more than ten kind of medicines such as Fructus Crataegi, the Rhizoma Atractylodis Macrocephalae, Carapax Trionycis, Radix Ginseng, Herba Cistanches and Calculus Bovis can both enhancing immunity, makes the spleen weightening finish, blocking nitrosamine formation synthetic suppresses the mutagenic action of aflatoxin B1 etc., prevents and treats arteriosclerosis, prevents the generation of lung, hepatic fibrosis.
15. tangible sedation is arranged, make the time lengthening of sleeping soundly, the intestines and stomach absorption function increases, absorb more nutrition, promote brains, each internal organs, tissue, skeleton, muscle, skin, hair again new life and libido increased functionality and fertility Zai Now, muscle power is strong, note meaning power obviously strengthens, ability to work doubles, and shows the merit of rejuvenation.
The specific embodiment
Following patient has used that benefit congenital defect, Fructus Alpiniae Oxyphyllae are kept fit, rejuvenescent medicine:
Case 1: Lee * * Meishan city, 45 years old Sichuan of man
Symptom: immunity degradation, repeatedly waist lower limb damage, normal lumbago and skelalgia, easily angry angry, dizzy, weak, hypomnesis can not be focused one's attention on.Began to take " mend congenital defect, Fructus Alpiniae Oxyphyllae are kept fit, rejuvenescent medicine " 12 days in April, 2008, various symptoms all disappear, and are in vigorous health, and memory increases, and ability to work strengthens, and glowing with health, it is younger that face becomes.
Case 2: open * * Mao Ershi village, Leigu Town, Beichuanqiangzu Autonomous County, 47 years old Sichuan of woman
Symptom: band is black in insomnia and dreamful sleep, the yellow complexion, and hair easily comes off, and easy catching a cold is easily absent-minded, and stupefied, mind is dimmed, cisco unity malfunction, pale tongue, few tongue, thready and weak pulse.Began to take " mend congenital defect, Fructus Alpiniae Oxyphyllae are kept fit, rejuvenescent medicine " on the 1st 15 days in December in 2008, various transference cures, health is strong and vigorous, and is glowing with health, and wrinkle reduces, and can participate in all physical works.
Case 3: Tang * * Shangri-la, 50 years old Yunnan of man
Symptom: ability to work is low, dyspepsia, difficult sleeping, dreaminess, easily wake up, and often can't fall asleep with perspiration malaise after waking up.Begin to take " mend congenital defect, Fructus Alpiniae Oxyphyllae are kept fit, rejuvenescent medicine " 2 days 6 times on June 25th, 2007, various symptoms all disappear, and ability to work strengthens.
Case 4: open * * county town, Luojiang County, Deyang, 89 years old Sichuan of man
Symptom: easily angry angry, obnubilation, the look dementia, slurred speech, neck is soft, often catches a cold, and action needs the people to assist in, the eyes muddiness, blurring of vision, yellow complexion, black, taste is light, anorexia, deep-thready pulse, less fur, pale tongue, tongue is shivered.Began to take " mend congenital defect, Fructus Alpiniae Oxyphyllae are kept fit, rejuvenescent medicine " 40 days on June 17th, 2009, diet heightens, conscious mind, and language is bright, and the waist knee joint is strong and vigorous, and freedom of movement is had rosy cheeks, and wrinkle reduces.
Case 5: Cai * * seven groups in woman 81 years old Sichuan volcano village, Wen Qing township, Huidong County
Symptom: diabetic history is arranged, and the bodily form is thin and weak, breathes unablely, and the waist lower limb is dumb, handicapped, insomnia and dreamful sleep, difficult sleeping, easily wake up, do not have enough sleep, feel dizzy, look dementia, dizziness and tinnitus, dysphonia, soreness of the waist and knees, handicapped, need the people to assist darkish complexion, pharyngoxerosis in, the tongue black fur, purplish tongue, thready and hesitant pulse.Began to take " mend congenital defect, Fructus Alpiniae Oxyphyllae are kept fit, rejuvenescent medicine " 46 days on October 26th, 2009, various morbid state disappear, conscious mind, and language is fluent, and the waist knee joint is strong and vigorous, freedom of movement, and help family to do a little housework.
Case 6: open * * city, 86 years old Jincheng City, Shanxi Province of man
Symptom: language performance is unclear, with dementia, and the immunity deficiency, visual deterioration, daily life can not be taken care of oneself, walking disorder, the extremity edema, malaise, the Mental fatigue cold extremities, timid cold.Began to take " mend congenital defect, Fructus Alpiniae Oxyphyllae are kept fit, rejuvenescent medicine " 60 days on March 12nd, 2008, vision restoration is normal, a good talker, and hypermnesia can be read a book and be read the newspaper, and explains to everybody, and the waist lower limb is strong, carries out the exercise of dash and practises taijiquan.
Case 7: Lee * * Manchu autonomous County of Qinglong, 9 years old Hebei province of man
Symptom: 3.8 jin of birth weights, congenital defect, suck the breast few the middle of the month, it is few to have a meal after the wean, and body constitution is poor, and is slight of figure, difficult sleeping, cry out in alarm in the dreaminess, often flu, nine years old just 20 jin, 1.1 meters of heights, nine years old one grade at primary school, poor memory, absent minded, learning capacity is low, and understandability is poor.Began to take " mend congenital defect, Fructus Alpiniae Oxyphyllae are kept fit, rejuvenescent medicine " 3 on August 29th, 2005, various symptoms have obvious change, continued to take 20 days, Lee * * the diet multiplication, hale and hearty, memory strengthens greatly, 3.2 jin of weight increase, height increases by 3.1 centimetres, and glowing with health, health is strong and vigorous.
Case 7: open * * 5 years old Liaoning Province of the woman Xin Bin of Fushun City Manchu
Symptom: pale complexion, IQ is low, and is easily sick, do not like activity, drowsiness, dull expression, obnubilation, bradykinesia is not had a liking for food, tongue fur duskiness and do purplish tongue, deep and hesitant pulse.In JIUYUE in 2006 began to take in 10th " mend not enough earlier, Fructus Alpiniae Oxyphyllae is kept fit, rejuvenescent medicine " 3 days, diet heightens, and has rosy cheeks, and is conscious, after continued to take 15 days, open * * bounce about, artistomia, the credit of living very much becomes lively and lovely.
Case 8: become * * Pingshan Mountain, Benxi, 32 years old Liaoning Province of man
Symptom: easy to be angry angry, anorexia, fatigue and weak, giddy, visual deterioration, distending pain in the head, hypomnesis, yellowish complexion, ability to work is poor, and mental work was just felt giddy in more than ten minute, wanted to close eyes, and is drowsiness.Began to take " mend congenital defect, Fructus Alpiniae Oxyphyllae are kept fit, rejuvenescent medicine " 1 day on May 25th, 2006, conscious mind is had a very good appetite, after continued to take 20 days, memory increases, ability to work is strengthened, nympholepsy, the mind shrewdness, whole body is full of strength.
Case 9: yellow * * governor Bai Xian Jinhua township, 32 years old Jilin of woman
Symptom: dizziness and blurred vision, weak, deficient in energy, fatiguability, energy are not concentrated, hypomnesis, greedy sleeping easily is stranded.
Began to take " mend congenital defect, Fructus Alpiniae Oxyphyllae are kept fit, rejuvenescent medicine " 7 days on January 20th, 2009, appetite heightens, and has rosy cheeks, all symptoms are all eliminated, conscious full of vitality, surpass the memory when young, surpass the ability to work of the former when phase of taking medicine.
Case 10: model * * Lianshui County, Huai, 35 years old Jiangsu Province of man
Symptom: anorexia, become thin, hypomnesis, ability to work is low, and complexion is turned to be yellow, and is easily angry angry, and insomnia and dreamful sleep is tired, works just to feel in more than ten minute and feels dizzy, and sleepy is felt, even is lain prone and just sink into a deep sleep on the table.Began to take " mend congenital defect, Fructus Alpiniae Oxyphyllae are kept fit, rejuvenescent medicine " on the 11st 2 days in JIUYUE in 2007, these morbid state are all eliminated, and take 7 days, the spirit multiplication, and memory, ability to work all surpass any period before of taking medicine.
Case 11: open * * do in the Xian Dun township in 29 years old Jiangsu Province of man
Symptom: waist soreness, skin is weary unable, nervous heart beating, malaise, absent minded, the profuse sweating of working out a little, deficient in energy, fatiguability is had a meal and is also felt tired, sleeping perspiration, pharyngoxerosis.Began to take " mend congenital defect, Fructus Alpiniae Oxyphyllae are kept fit, rejuvenescent medicine " on the 23rd in JIUYUE in 2007, only 1 day, as above various symptoms were all eliminated, and continued to have taken 7 days, and conscious energy surpasses any period in the past, and health is healthy and strong especially.
Case 12: model * * Taihu County, Anqing, 31 years old Anhui Province of woman
Symptom: unhappy in the heart, eye is dry and astringent, usually easily flies into a rage, and dizzy tinnitus, the nervous heart is tired, and memory obviously goes down, vague mind sometimes, tetraparesis is unable and stiff, soreness of the waist and knees, frequent flu, difficult sleeping, dreaming often and waking easily was not passed through the dispute numbness in eight months.Began to take " mend congenital defect, Fructus Alpiniae Oxyphyllae are kept fit, rejuvenescent medicine " 3 days on April 13rd, 2008, various symptoms are all removed, and begin in the period, continue to have taken 10 days medicines, health credit alive is strong and vigorous, energetic, glowing with health, and the effect of beauty treatment is arranged, make model * * become younger, more beautiful.

Claims (1)

1. enhance immunity; improve the pharmaceutical composition of human body constitution; comprise following component by weight: Rhizoma Cyperi 1-10; Radix Curcumae 2-12; Fructus Citri Sarcodactylis 0.1-10; Radix Aucklandiae 0.1-8; Lignum Aquilariae Resinatum 0.1-6; Fructus Aurantii 0.1-15; Semen Persicae 0.1-12; Flos Carthami 0.01-30; Squama Manis 1-10; Radix Trichosanthis 2-10; Radix Salviae Miltiorrhizae 0.001-30; Ramulus Cinnamomi 2-10; Radix Bupleuri 1-12; Radix Platycodonis 1-12; Radix Achyranthis Bidentatae 0.001-20; Radix Ginseng Rubra 0.001-20; Rhizoma Atractylodis Macrocephalae 0.001-20; Poria 1-20; Radix Glycyrrhizae Preparata 1-12; Fructus Jujubae 0.1-8; Radix Angelicae Sinensis 0.1-12; Radix Rehmanniae Preparata 1-18; Radix Paeoniae Alba 1-15; Rhizoma Chuanxiong 1-9; Placenta Hominis 0.01-20; Colla cornus cervi 0.01-20; Cortex Eucommiae 1-10; Herba Cistanches 0.01-20; Carapax et Plastrum Testudinis 0.001-50; Colla Plastri Testudinis 0.01-20; Colla Corii Asini 0.01-15; Fructus Lycii 1-50; Radix Asparagi 1-12; Radix Ophiopogonis 1-12; Radix Rehmanniae 0.01-30; Cortex Phellodendri 1-10; Semen Armeniacae Amarum 1-12; Fructus Hordei Germinatus 2-20; Fructus Setariae Germinatus 2-20; burnt short, bristly hair or beard 1-18; Massa Medicata Fermentata 1-18; Semen Raphani 1-12; chicken gold 1-13; Arillus Longan 0.01-18; Semen Ziziphi Spinosae 1-20; Poria cum Radix Pini 1-20; Os Draconis 0.01-30; Rhizoma Acori Graminei 1-30; Radix Polygalae 1-20; Calculus Bovis 0.00001-6; Cinnabaris 0.001-5; medicine of the present invention not only can be removed the weak disease that congenital defect causes, and to few; in; blue or green; prime of life learning memory is low; have bad physiques; ability to work is low; dementia has good therapeutical effect.
CN2010101469545A 2010-04-09 2010-04-15 Medicinal composition for strengthening immunity and improving human body condition Pending CN102210838A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104095935A (en) * 2014-06-25 2014-10-15 北京神石医药科技开发有限公司 Chinese herbal preparation for preventing and curing acute mountain sickness and preparation method for Chinese herbal preparation
CN104688999A (en) * 2015-03-20 2015-06-10 杜卫卫 Chinese herbal preparation for immunity enhancement
CN104705720A (en) * 2013-12-11 2015-06-17 张俊 Functional beverage for regulating female internal secretion
WO2017197784A1 (en) * 2016-05-20 2017-11-23 顾香 Wolfberry and ginseng liquor
CN109355153A (en) * 2018-12-07 2019-02-19 吉林省九圣源生物科技有限公司 A kind of health food and preparation method thereof
CN111514167A (en) * 2020-05-09 2020-08-11 北京航空航天大学 Application of donkey-hide gelatin in product for relieving oxidative stress injury of cells

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104705720A (en) * 2013-12-11 2015-06-17 张俊 Functional beverage for regulating female internal secretion
CN104705720B (en) * 2013-12-11 2016-07-06 张俊 A kind of functional drinks regulating female incretion
CN104095935A (en) * 2014-06-25 2014-10-15 北京神石医药科技开发有限公司 Chinese herbal preparation for preventing and curing acute mountain sickness and preparation method for Chinese herbal preparation
CN104095935B (en) * 2014-06-25 2016-05-25 北京神石医药科技开发有限公司 Chinese medicine preparation of a kind of prevention and treatment acute high altitude reaction and preparation method thereof
CN104688999A (en) * 2015-03-20 2015-06-10 杜卫卫 Chinese herbal preparation for immunity enhancement
WO2017197784A1 (en) * 2016-05-20 2017-11-23 顾香 Wolfberry and ginseng liquor
CN109355153A (en) * 2018-12-07 2019-02-19 吉林省九圣源生物科技有限公司 A kind of health food and preparation method thereof
CN111514167A (en) * 2020-05-09 2020-08-11 北京航空航天大学 Application of donkey-hide gelatin in product for relieving oxidative stress injury of cells
CN111514167B (en) * 2020-05-09 2022-05-24 北京航空航天大学 Application of donkey-hide gelatin in product for relieving oxidative stress injury of cells

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Application publication date: 20111012