CN102526698A - Cordyceps polypeptide amino acid nutrient solution - Google Patents

Abstract

The invention belongs to functional nutrition, and particularly relates to cordyceps polypeptide amino acid nutrient solution which is prepared by cordyceps, barbary wolfberry fruit, Chinese date, malt, hawthorn, pericarpium citri reticulatae, eight essential amino acids, arginine, proline, glutamic acid, theanine, gamma-aminobutyric acid, glycine, alanine, cysteine, glutamine, aspartate, histidine, glutathione, sheep placenta, beta-glucan, selenium-enriched yeast, carnosine and zinc. The product is an optical nutrient supplement with the functions of strengthening the spleen and the stomach, promoting digestion, tonifying qi and nourishing blood, enhancing protein synthesis, supplying organism nutrition, adjusting organism functions, preventing sub-health, enhancing the immunity, resisting virus, delaying ageing, beautifying the face, delaying climacterium, improving sleep, resisting fatigue, reducing the chemoradiotherapy damage, enhancing wound healing and achieving recovery and rehabilitation of surgical diseases. The manufacturing process of the product comprises the following steps of: mixing and crushing plant materials, carrying twice extraction with boiling water, mixing amino acid into filtrate, melting a zinc material, stirring, filtering, filling, sealing, sterilizing, inspecting and packaging into a normal product.

Description

The Chinese caterpillar fungus polypeptide amino-acid nutrition liquid

One, technical field: the invention belongs to the high-touch feature nutriment.Especially with raw materials such as natural plants Cordyceps, Fructus Lycii, Fructus Jujubae, Fructus Hordei Germinatus, Fructus Crataegi, Pericarpium Citri Reticulatae, lysine, phenylalanine+tyrosine, methionine+cystine, leucine, isoleucine, threonine, tryptophan, valine, arginine, proline, glutamic acid, theanine, GABA, glycine, alanine, cysteine, glutamine, aspartic acid, histidine, glutathion, carnosine, sheep placental extract, beta glucan, yeast rich in selenium, zinc gluconate; Take advanced technologies, the functional nutriment that processes.

Two, background technology: the functional nutriment that this invention is processed with raw materials such as natural plants Cordyceps, Fructus Lycii, Fructus Jujubae, Fructus Hordei Germinatus, Fructus Crataegi, 8 kinds of essential amino acids of Pericarpium Citri Reticulatae, arginine, proline, glutamic acid, sheep placental extract, zinc.This product has strengthening the spleen and stomach, digestion promoting, benefiting qi and nourishing blood, promotion protein synthesis, supplies with body nutrition; Regulate body function, prevent and treat subhealth state, enhancing immunity, antiviral, slow down aging, looks improving and the skin nourishing, delay climacteric, improve sleep, resisting fatigue, the infringement of attenuating chemicotherapy, promote wound healing, operation back, the best-of-breed functionality nutritional supplement of recovering.Also do not have like product to occur in the market, develop this product and can be a kind of function nutrition new product to market is provided.

Three, summary of the invention: along with China's rapid economy development; National living standard improves constantly and the expection of human longevity prolongs; Its health care consciousness also strengthens day by day; Great transformation has also taken place in people's medical model and threpsology's thinking, and the development drink with function has good economic implications and sociology is worth.The drink with function industry gets into expansion development expection rapidly in recent years, will bring very big influence to people's life health.

Four; Composition of raw materials: 1 kilogram of Cordyceps; 5 kilograms of Fructus Lycii; 6 kilograms in Fructus Jujubae; 6 kilograms in Fructus Hordei Germinatus; 5 kilograms of Fructus Crataegis; 3 kilograms of Pericarpium Citri Reticulataes; 1.14 kilograms of lysines; 1.20 kilograms of phenylalanine+tyrosine; 0.96 kilogram of methionine+cystine; 1.08 kilograms of isoleucine; 1.20 kilograms of threonine; 0.24 kilogram of tryptophan; 0.84 kilogram of valine; 1 kilogram of arginine; 0.5 kilogram of proline; 0.6 kilogram in glutamic acid; 0.5 kilogram of theanine; 0.75 kilogram of GABA; 0.4 kilogram of glutamine; 0.5 kilogram of aspartic acid; 0.4 kilogram of histidine; 0.6 kilogram of glutathion; 0.5 kilogram of carnosine; 1.2 kilograms of sheep placental extract; 1 kilogram of beta glucan; 1 kilogram of yeast rich in selenium; Zinc 15 grams.

Five, technical scheme:

(1) hide Cordyceps (Cordyceps): being to be grown in a kind of microorganism (fungus body) under the Qinghai-Tibet 3500-4500 rice special environment, is that China's Tibetan medicine is protected the medical material of Chinese medicine simply in the storehouse.In global Chinese, there is widely U.S.A transcribe; Cordyceps is always regarded as the panacea of treatment weakness by common people; Be (Cordyceps, Cornu Cervi Pantotrichum, Radix Ginseng) first of the Chinese herbal medicine " three mend "; Enjoy the good name of " the east legend are very precious " in the world and be described as the splendid Chinese crude drug of disease-resistant anti-cancer, bring the world health by the expert.

Cordyceps is an Ergota Compositae fungus Cordyceps, colonizes in Stroma and larva cadaveric complex on the Hepialidae insect larvae.Warm in nature, sweet in the mouth are returned kidney, lung meridian.Have nourishing lung and kidney, mend smart marrow, Yin Yang balancing, hemostasis and phlegm, reinforcement myocardial function, the function of delaying senility of giving birth to.

Be adapted to heart failure, heart and lung diseases, to cancer-resisting, anemia weakness, hepatitis B, raising immune function of human body work the effect of consolidating.

Chemical constituent: Cordyceps contains saponins, cordycepic acid, Cordyceps polysaccharide, nucleotide, superoxide dismutase various active goods and materials such as (SOD), and aminoacid, vitamin and trace element, selenium, calcium, potassium, manganese, zinc etc.

Pharmacological action: 1, regulate immunologic function: (1) is to the potentiation of mononuclear phagocyte system function: Cordyceps water extract can obviously improve colloid carbon clearance degree in the mice blood; To the mouse monokaryon phagocyte; Peritoneal macrophage, phagocytic functions such as reticuloendothelial system have tangible activation.It is bright to engulf test card in the body, and these article can significantly improve the phagocytic function of Turnover of Mouse Peritoneal Macrophages.

(2) to the influence of humoral immunization: Cordyceps and Cordyceps polysaccharide can make mice serum 1gE content obviously increase, and have improved the serum hemolysin level, induce splenocyte to express the IL-2 receptor.

(3) increase natural killer cell (NK) activity: research shows that the administration of Cordyceps alcohol extraction liquid can obviously strengthen the killing activity of the inside and outside NK pair cell of mice body.

2, kidney invigorating and YANG supporting: Cordyceps scalable renal function, nourishing YIN is YANG invigorating again, and is not empty not high, vital base and primordial QI consolidating, tonification kidney tonifying.But Cordyceps also has androgen effect spermatogenesis, and to impotence and seminal emission, the disease of the insufficiency of kidney-YANG of soreness of waist and knee joint is effective in cure.

3, adjusting sexual function: Cordyceps has certain androgen-like action, can make the weightening finish of castration male rat childhood seminal vesicle.Male mouse blood plasma cortisol content is increased for mouse stomach, adrenal gland's cholesterol is increased, adrenal gland's weightening finish has preventive and therapeutic effect to " deficiency of yang type " due to the oxidation cortisone, and sexual disorder is had the adjusting restitution.In addition, Cordyceps also has the synthetic and secretion of promotion and adrenal cortex reinforcing hormone.

4, defying age: Cordyceps can alleviate the infringement to the body biochemical process that descends and cause thus owing to the old and feeble maincenter catecholamine levels that causes, and removes human body harmful's free radical, thereby plays slow down aging, the effect of good health and a long life.The defying age result of the test shows that the Cordyceps polysaccharide of separate sources all has prolongation effect in various degree to life span of drosophila melanogaster, thereby the proof Cordyceps polysaccharide has function in delaying senility.

5, antioxidation: Cordyceps can suppress lipid peroxidation and generate; Strengthen erythrocyte superoxide dismutase vigor.Cordyceps can suppress MDA in rat, the mouse brain.According to another report, TaiWan, China ancient Chinese name for Venus hospital carries out human trial to the nephrotic, finds to take Cordyceps after 1 month, and tangible antioxidation reaction is arranged in the blood.

6, looks improving and the skin nourishing: in present medical circle, in confessed seven big types of anti-aging beauty-care active component, Cordyceps just contains five big types, is respectively polysaccharide, aminoacid, polypeptide (protein), nucleic acid and vitamin (other two big flavonoid and soap class).Cordyceps also has endocrine regulation, and tangible calmness and syngignoscism are arranged, and has the looks improving and the skin nourishing effect.

7, antitumor: Cordyceps has the synthetic function of human activin DNA, can strengthen autoimmunity, and leukocyte is engulfed the oncocyte encirclement of the bad degeneration of human body and produced normal cell, oncocyte is reduced or disappearance, and tumor also can slowly be contracted to disappearance.The Cordyceps water decoction has certain inhibitory action to mice S180.Antitumous effect to Ismipur has potentiation, and the growth of mouse subcutaneous transplanting lung tumor is had the obvious suppression effect.According to another report, Cordyceps mouse entity S180 tumor etc. is had inhibitory action, intravenous effect is 100%.The average inhibitory rate 45.71% of report is also arranged.

Cordyceps polysaccharide: have anticancer and immunosuppressive action: with lotus tumor BALB/C is that model is observed Cordyceps polysaccharide and can obviously be suppressed tumor growth. research shows; Cordyceps polysaccharide can activate phagocytic function and DTH reaction; Directly or indirectly discharge the cytotoxic factor killing tumor cell; Suppress tumor growth, prove that Cordyceps polysaccharide has obvious antineoplastic.

8, blood pressure lowering, blood fat reducing: the factor that causes cardiovascular disease is a lot, but mainly is that blood fat increases and causes arteriosclerosis to cause, therefore controlling hyperlipemia disease just becomes the key of preventing and treating cardiovascular disease.Cordyceps confirms through the clinical observation of strictness, and serum total cholesterol (CT) concentration, serum triglycerides (TG) concentration are significantly descended, and has tangible blood pressure lowering, the effect of blood fat reducing.

9, strengthen the cardiac pulse ability, Cordyceps mycelium extract 100ug/ml can obviously strengthen the active contraction intensity of rat in the atrium, prolongs contraction time.

10, resisting myocardial ischemia: hide Cordyceps extracting solution 0.66mg/ml, the isolated rat myocardial cell that can obviously the slow down rate of beating can make exsomatize Cavia porcellus and Cor Leporis rule slow down heart throughput rate and CF increase.The mycelium alcohol extract can increase the anesthetized dog CF, reduces arteria coronaria, brain and peripheral vascular resistance.Quiet notes of Cordyceps fermentation liquid 0.15g/kg and irritate stomach and Cor Leporis myocardial ischemia, thyroxine due to the Neurohypophysin are added stress in rats property myocardial infarction has protective effect due to the norepinephrine.

11, anti-arrhythmia: the Cordyceps alcohol extract can obviously resist aconitine, the dosis tolerata that rat ventricular that BaCl2 brings out and ouabain are poisoned.

12, treatment cardiovascular diseases, strengthen cardio and vascular function: Cordyceps has the adjusting cardio and vascular function, and blood pressure lowering is arranged; Blood fat reducing and reduction myocardial oxygen consumption improve cardiac muscle and cerebral anoxia, arrhythmia; Resisting fatigue and the anti-ageing effect of waiting for a long time make the running of cardiovascular and cerebrovascular vessel normal health.

13, resisting fatigue, high temperature resistant, anoxia enduring: with Cordyceps mycelium extract 100-200mg/kg mouse swimming test, the result proves that swimming time prolongs, and has the resistivity under physical strength reinforcing and the stressed condition.Cordyceps group mouse stomach has the high temperature resistant effect of obvious anti-fatigue.The lumbar injection Cordyceps has the increase resisting oxygen lack.

It is reported that the double-blind trial of Medical School of Peking University confirms; Cordyceps far surpasses Radix Ginseng in the lifting of physical ability and explosive force; The Chinese female player who in 1993 and Olympic Games Women's 1000m in 1994 race, wins the title finishes the full distance to make 42 seconds of whole world motion circle shock with breaking a record. and its reason is that the athlete takes Cordyceps extract for a long time, to promote explosive force; So the health preserving effect of Cordyceps receives attracting attention of west biochemical medicine circle.

14, protect the liver: Cordyceps has improves the effect that chronic type b, hepatitis C symptom have the virus removed.Surface antigen is turned out cloudy; Make liver function recovery normal, reach the effect of treating both the principal and secondary aspects of a disease, according to another report; Cordyceps sinensis polysaccharide liposome (CPL) can significantly reduce the activity of ALT and AST in the hepatic injury mice serum; Murine liver tissue, pathological section show, the CPL of senior middle school's agent has protective effect to the CPL that the mouse liver injury due to amino half sugar of D-and middle agent are to the hepatic injury due to four carbonoxides.The prompting Cordyceps has function for protecting liver and reducing enzyme activity.Cordyceps has certain preventive and therapeutic effect to hepatitis B in addition.。

15, blood sugar lowering: the CHWC polysaccharide in the Cordyceps thalline, lumbar injection 50mg/kg has significant hypoglycemic activity, onset in 3 hours.To the alloxan diabetes model mice, the obvious functions of blood sugar effect is arranged, descend about 40% than matched group.

16, antiasthmatic-antitussive has better curative effect to emphysema, tracheitis: be the common respiratory tract infection of respiratory system disease spring, pulmonary infection; Disease such as chronic cough, asthma; Because its clinical shape is with influenza and for similar, much human does not all attract great attention, thus delay treatment.Lung heat clearing good medicine Cordyceps is discharged through the guiding pus, removes outmoded expectorant piece, nourishes lung tissue; The activate immunity function is removed respiratory disorder, will effect a permanent cure, consolidates, nourish and combine; Fundamentally improve lung functions, it is active to recover mucosa, improves immunologic function.

The also expansible bronchial smooth muscle of Cordyceps strengthens epinephrine, and to the lung qi loss, the disease that the lung power consumption is hindered dyspnea due to deficiency, phthisical cough expectorant blood has a significant effect.It is relevant with deficiency of both the lung and kidney that the traditional Chinese medical science thinks that old-slow-bronchial tube shows effect repeatedly.Cordyceps is warm in nature, vital essence replenishing and marrow benifiting, and nourishing lung and kidney, this thing is protected lung qi." from Bencao Congxin " record, Cordyceps protects the lung kidney tonifying, and hemostasis and phlegm ends the phthisical cough effect.Its nature and flavor, sweet, warm, go into lung, kidney channel.But it is bright to go into the lung tonifying the lung, and following kidney then tonify deficiency is cloudy, has lung benefiting and protects lung, relieving cough and resolving phlegm, hemostasis tonifying deficiency, effects such as strong vital essence.Be usually used in treating chronic cough dyspnea due to deficiency, phthisical cough spitting of blood, sexual impotence, seminal emission, soreness of waist and knee joint etc.The chronic cough dyspnea due to deficiency that the treatment old-slow-bronchial tube causes.

17, tonify deficiency, postoperative rehabilitation effect: Cordyceps has anticancer, antiviral special efficacy, and the effect that Cordyceps polysaccharide has strengthening the body resistance, improves immunologic function contains abundant vitamin and selenium element in the Cordyceps; Can both the enhancing human body immunity system, build up resistance.Patient has consumed a large amount of nutrient substance during sick, take the nutritional labeling that Cordyceps just in time can be replenished the various urgent needs of body this moment, recovers patient's muscle power, and is very favourable to physical rehabilitation.Postoperative patient has a delicate constitution, and resists the virus attack ability and obviously reduces, and wound healing also is badly in need of nutrition goods and materials such as a large amount of protein and vitamin.Protein content is repaired damaged tissues in the Cordyceps up to 27.81% pair, and recovering body constitution has tangible effect.

18, memory reinforcing: contained nucleotides bioactive ingredients in the Cordyceps; Edible back is found; The increase of hemoglobin and oxygen affinity helps supplying with cerebral tissue; The increase of cell oxygen carrying content, thus the tired and raising ability of learning and memory that brain is not enough because of oxygen supply and shortage nutrition causes eliminated.According to another report, Japanology finds that nucleotide pair ischemic neurocyte has protective effect.The result finds that the mouse brain cell mortality of diet nucleotide is fewer.Experiment showed, edible nucleotide pair ischemic, neurocyte has protective effect, takes nucleotide and in zoopery, shows and can prevention of brain block.

(2) Fructus Lycii (Lyciam barbarnm extraat), Fructus Lycii is the matrimony vine of solanaceae plant mature fruit.Property is put down, sweet in the mouth.Return liver, kidney channel.Effect with nourishing the liver and kidney, replenishing vital essence to improve eyesight, lung moistening.Be used for that asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat are quenched one's thirst, blood deficiency and yellow complexion, blurred vision are not clear etc.Modern medicine study thinks, Fructus Lycii has enhancing immunity, resisting fatigue, blood pressure lowering, blood fat reducing, blood sugar lowering, the liver protecting, fat-reducing, defying age, function such as anticancer.

Chemical constituent: Fructus Lycii contains trace element such as multivitamins such as polysaccharide, aminoacid, betanin, carotene, vitamin B, vitamin C, nicotinic acid and manganese, chromium, zinc, copper, magnesium, calcium, germanium, cobalt.

Pharmacological action: 1, enhancing immunity: mouse gavaging water extract or intramuscular injection alcohol extract all can significantly strengthen the phagocytic activity of its reticuloendothelial system to india ink.Water extract or LBP all can promote lysozyme activity in Turnover of Mouse Peritoneal Macrophages phagocytic function and the serum.Give normal or Aged Mice filling clothes or abdomen LBP, can significantly strengthen peritoneal macrophage c ₃The acceptor number of b and Fc and vigor can make the Aged Mice suppressor T lymphocyte regulate the level that antibody function returns to adult mice.The pure article of LBP have more significant effect of immune response than bullion; Each item immune indexes (comprise immune organ quality, the macrophage phagocytic effect of nonspecific immunity, the serum hemolysin of specific humoral immunity, moving back hair style allergy, lymhocyte transformation rate, E rosette formation etc. in the specific cellular immunity) all has significant difference.

2, the liver protecting, AFL: Fructus Lycii extract has certain function to the liver protecting and AFL.Modern medicine study is found, contains a kind of effective ingredient-betanin in the Fructus Lycii, and it is very effective to the treatment hepatic disease.Experiment shows that betanin has the fat of inhibition in hepatocyte, to deposit, and promotes the effect of liver cell regeneration.In addition, the middle betanin of Fructus Lycii can prevent that excess fat is stored in the liver, and the effect of anti-fatty liver is arranged, and it is reported, feeds water extract or betanin feedstuff to ccl through rat for a long time ₄The hepatic injury that causes has protective effect, and the obviously variation of lipid in transaminase lowering and the liver can suppress lipidosis and promotion hepatocyte new life in the liver, and the liver lipid peroxidation injury is had the significant protection effect.

3, radioprotective: LBP 2 (LBP ₂) can obviously promote the recovery of radiation damage immune function of mice can make irradiated mouse thymus index splenocyte to ConA, the breeder reactions of LPS etc. all obviously strengthen.Show that its treatment to radiation sickness is significant.

4, anti-stress: after electric shock added the irradiation of low dosage gamma ray, the heavy index of the spleen of rat obviously reduced, and the cerebral cortex index obviously raises, and spleen and cerebral cortex total lipid content obviously reduce the lipid peroxidation product malonaldehyde and obviously increase.Visible administration group spleen of abdominal part injection LBP and the total lipid level of brain homogenate are near matched group, and spleen homogenate MDA content significantly reduces.Show that LBP has anti-stress effect.

5, anoxia enduring: the Fructus Lycii decoct is injected to mouse peritoneal, and its hypoxia-bearing capability is compared with matched group life span 27.9 ± 1.3min, and Fructus Lycii is 37.5 ± 2.5min.Show that Fructus Lycii has resisting oxygen lack.

6, resisting fatigue: Fructus Lycii can improve hydroxyproline concentration, thereby improve muscular strength anti-fatigue ability is strengthened.Fructus Lycii also can obviously prolong the swimming with a load attached to the body time of mice, has antifatigue effect, and strong effect is also arranged.

(3) Fructus Jujubae (Jujub fruit) has another name called Fructus Jujubae.For the dried fruit of Rhamnaceae plant Fructus Jujubae ripe.Warm in nature, sweet in the mouth.Return spleen, stomach warp.Have invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, born fluid, separate poison of drug, relax the effect of the property of medicine.Modern medicine study is thought, Fructus Jujubae enhancing immunity, the liver protecting, resisting fatigue, cholesterol reducing, antioxidation, antitumor, the anti-ageing function of waiting for a long time.

Chemical constituent: Fructus Jujubae contains protein, several amino acids, Saponin, flavone, alkaloid, organic acid, sterol, polysaccharide, vitamin A, vitamin B ₂, vitamin C, nicotinic acid, vitamin E and carotene, calcium, phosphorus, ferrum, magnesium etc.

Pharmacological action: 1, enhancing immunity: research shows, can obviously improve percent and the phagocytic index that its peritoneal macrophage is engulfed chicken red blood cell in 7 days for mouse stomach with Fructus Jujubae decoct 8.25g/kg; To the cell of cycli phosphate amide induced mice, platelet and hemoglobin reduction all have to be increased and restitution, and hemopoietic function of bone marrow is also had protective effect in the time of 15 days.According to another report, Fructus Jujubae neutral polysaccharide (TDP-N) can cause Ca in the mouse peritoneal cell ²⁺Concentration obviously raises.Jujube polysaccharide is given D-galactose aging model mouse gavaging, can obvious anti-thymus, the spleen atrophy.

2, the liver protecting: research confirms that to the rabbit of carbon tetrachloride hepatic injury, took the Fructus Jujubae decoct continuously 7 days, serum rabbit albumen and albumin obviously improve, and prove that Fructus Jujubae has hepatoprotective effect.Research is proof also, and the Fructus Jujubae decoct can also obviously increase normal mouse liver blood flow amount, and can prevent the liver blood flow amount decline due to the carbon tetrachloride, also can alleviate mouse liver cell swelling, necrosis and fat range degree simultaneously.Fructus Jujubae contains the triterpenoid compound composition in addition, can suppress the activity of liver viroid.Fructus Jujubae can also improve the phagocytic function of mononuclear phagocyte system in the body, and liver-protective effect is arranged.

3, increase muscle strength, resisting fatigue: it is reported; Give the male mice lumbar injection with 30% Fructus Jujubae decoct body weight 0.3ml/kg; Raised for 3 weeks, Fructus Jujubae group mice average weight increases 3.0g as a result, and matched group then on average increases 1.6g; Two groups is 2min30S, shows that therefore Fructus Jujubae has the muscular strength of increasing and antifatigue effect.According to another report, take Fructus Jujubae decoct 1.25-8.25g/kg to mice, obviously prolong the swimming time of mice after 7 days, obvious the increasing of 3 week back body weight shows to have strong effect.

4, tranquillizing and allaying excitement: contained naringenin C glucoside (glucosides class) can reduce autonomic movement, the stimulation reflection of animal in the Fructus Jujubae, and the catalepsis effect has inhibitory action to the central nervous system.According to another Japan's report, isolated flavone in the Fructus Jujubae ethanol extraction-two-glucoside A has the central nerve inhibition effect through the pharmacological evaluation proof, and calmness is arranged, syngignoscism.

5, convulsion: research shows that Fructus Jujubae has tangible anticonvulsant action, falls (0-5 year) with GANMAI DAZAO TANG treatment emotion 8; The result shows, all finds in week that at 3-4 the inhibition effect is arranged, and research shows; The GANMAI DAZAO TANG sedation matches and can bring into play stronger drug effect; Because the peace and quiet effect and the excitation of this prescription are in the sleepiness that neither causes infant, do not reduce again and bring into play under its active situation, so be safely and effectively to the baby.

6, blood pressure lowering: contained benzyl alcohol glucosides, naringenin (multiple chemical compound such as glucosides) have the effect of the blood pressure lowering of apparent Millefolium in the Fructus Jujubae.

7, antitumor: Fructus Jujubae has the anticancer proliferation function.Wherein belulinic acid Betulinic acid and Crataegolic acid have inhibitory action to S180.Fructus Jujubae has certain inhibitory action to the rat stomach adenocarcinoma that N-methyl-nitro-N-nitrosoguanidine (MNNe) brings out.The rat of handling with 100 ц g/ml, MNNe is after 7 months, fed in continuous 8 months its rat gastric gland incidence rate of Fructus Jujubae dry fruit (1g/d) and matched group MNNe continuously hello 10 months) compared apparent difference.Application sister chromatid exchange technology is given mouse gavaging 0.58/ml Fructus Jujubae aqueous extract, can obviously reduce the rising phenomenon of sister chromosome monomer commutative rate due to the cycli phosphate amide, shows that Fructus Jujubae has antimutagenic effect.The effective ingredient dammarane type saponin of Fructus Jujubae and ginsenoside are that homologue has antimutagenic activity.

8, antioxidation: Fructus Jujubae extract shows that to the experimental result that influences that SOD in mouse red blood cell, blood plasma, the hepatic tissue and MDA content carry out the Fructus Jujubae extract that mice is drunk variable concentrations has the effect of removing free radical and enhancing body anti peroxidation of lipid.

9, strong body constitution, prolong and decline: the health preserving proverb of " eating three Fructus Jujubaes, bearing one's age well all the life in 1st " at China's folklore.Fructus Jujubae is the sweet flat benefiting qi and nourishing blood good merchantable brands of a kind of nature and flavor.Over thousands of years, Fructus Jujubae enjoys treasuring of people, also is regarded as the health food that nourishes blood vessels, strong taste.Said as Compendium of Material Medica, the Fructus Jujubae regulating the spleen and stomach supports temper, flat gastric qi, logical nine orifices, help 12 through, mend not enough in weak breath, few body fluid, the body, frightened heaviness of limbs and hundred medicines, clothes are made light of one's life by commiting suicide and are prolonged life for a long time.It is reported that Britain's medical research finds that Fructus Jujubae shows that to physical weakness person's experiment the person is fast more than 3 times than eating the vitamin medicaments merely for the speed that every health of eating Fructus Jujubae is continuously recovered.

(4) Fructus Crataegi (Hawthorn) has another name called the Fructus Pyri Pashiae fruit.Fruit for the Fructus Crataegi of rosaceous plant.Slightly warm in nature, sour in the mouth, sweet.Return spleen, stomach, liver warp.Have promoting digestion and removing stagnation, be good for the stomach, effect such as promoting blood circulation to remove blood stasis.Be used for meat stagnation, children's's infantile dyspepsia, abdominal distention, dysentery, have loose bowels etc.Modern study is thought functions such as Fructus Crataegi has enhancing immunity, antibiotic, heart tonifying, anoxia enduring, protects the liver, blood fat reducing, antitumor.

Chemical constituent: Fructus Crataegi contains compositions such as organic acid, flavone, vitamin C, carotene.

Pharmacological action: 1, enhancing immunity: Fructus Crataegi all has content, serum coagulation antibody titre, painstaking effort T lymphocyte E rosette forming rate and the T lymhocyte transformation rate of rabbit anteserum lysozyme and increases effect significantly, explains that Fructus Crataegi all has facilitation to humoral immunization and cellular immunization.

2, aid digestion: Fructus Crataegi can increase secretion, the facilitating digestion of digestive enzyme in the stomach.Contained lipase can promote steatolysis; Contained organic acid such as Crataegolic acid can improve protease activities, and carnivorous being prone to digested.Zoopery shows that the Fructus Crataegi water decoction has obvious facilitation to the rat gastric secretion.Increase by 2.19 times than rat basic gastric secretion amount.

3, antibiotic: the Fructus Crataegi water decoction all has stronger inhibitory action to staphylococcus aureus, anthrax.Semen Crataegi slide oil also has the obvious suppression effect to dysentery bacterium, escherichia coli.

4, heart tonifying: Fructus Crataegi extract to Bufo siccus at body and exsomatize normal and tired heart all has certain cardiotonic.Between 20%-30%, and the persistent period is longer to heart contraction enhancing rate.According to another report, Fructus Crataegi can increase myocardial contraction and CO, and the Fructus Crataegi triterpenic acid has the effect of preparatory stroke to the weak heart due to tired naturally or 10% chloral hydrate.

5, arrhythmia: hawthorn extract has inhibitory action to rabbit because of the arrhythmia that pituitrin causes; The arrhythmia that Fructus Crataegi flavone and Saponin can make rabbit cause because of aconitine also has the normal effect of promotion.

6, coronary blood flow increasing: haw thorn granule all has the effect of dilating coronary blood vessel, coronary blood flow increasing to rabbit, dog.Prove that with radioactivity 86 rubidium measurements Fructus Crataegi flavone, hydrolyzate all can increase mouse cardiac muscle nutrient flow amount, wherein stronger with the effect of Fructus Crataegi hydrolyzate.In coronary blood flow increasing, can also reduce heart oxygen consumption and coefficient of oxygen utilization.In addition, Fructus Crataegi has protective effect to the impatient property of rabbit experiment myocardial ischemia.

7, anoxia enduring: the same resisting oxygen lack that highly significant is arranged with propranolol of Fructus Crataegi can prolong the time-to-live of mice.

8, resisting fatigue: the Fructus Crataegi polysaccharide has the antifatigue effect.This polysaccharide can reduce lactic acid in the body, but and the significant prolongation body hypoxia-bearing time, improve the anoxia ability, reduce serum urea nitrogen, promote the glycogen deposit to improve hepatic glycogen content, thereby have antifatigue effect.

9, tranquilizing soporific: zoopery shows that Fructus Crataegi can significant prolongation white mice pentobarbital sodium sleep time.

(5) Fructus Hordei Germinatus (mait) forms through water logging bubble, germination after drying for the mature seed of standing grain section herbaceous plant Fructus Hordei Vulgaris.Property is put down, and sweet in the mouth has spleen benefiting and stimulating the appetite, promote qi circulation digestion promoting and galactopoiesis function.Be used for food stagnation and do not disappear, effects such as distension and fullness in the abdomen, inappetence.

Chemical constituent: starch-containing hydrolytic enzyme, protease and starch protein, maltose, vitamin B complex, fatty oil, phospholipid, dextrin, maltose, glucose etc.

Physiological function: 1, facilitating digestion: the Fructus Hordei Germinatus decoct has certain facilitation to pepsin and gastric acid secretion.Contained amylase and vitamin B group have digestion-aid effect.

2, blood sugar lowering: the Fructus Hordei Germinatus preserved material can make the blood glucose of people and rabbit descend, and water extracting alcohol deposition thing highly finished product 5% injection of grain is injected 200mg to rabbit, can make blood glucose descend 40%, and keep more than 7 hours.

3, blood fat reducing: feed Carnis Coturnicis japonicae 10g/d with Fructus Hordei Germinatus, can significantly resist arteriosclerosis due to the high lipid food, its effect is better than inositol nicotinate, reduces serum cholesterol, high density lipoprotein increasing.

4, lactogenic: Fructus Hordei Germinatus (parched to brown) can make the Ruzhong serum prolactin antagonist of the female Mus of suckling increase, female molluscum contagiosum gland acinus expansion, and milk is bright to be full of, and shows good galgctogogue action.

5, other: the pharmacological action characteristics of hordenine are similar with epinephrine, can strengthen the nervous of the sub-official of Cavia porcellus and motion, can excited heart, vasoconstrictive, expansion bronchus suppresses bowel movement, and radiation injury is had protective effect.The oxidative damage of Fructus Hordei Germinatus extract maltol pair cell has protective effect.

(6) Pericarpium Citri Reticulatae (Mandarine Peel) belongs to the dry peel of various plants together for Rutaceae plant Fructus Citri tangerinae and phase.Warm in nature, bitter in the mouth, suffering, have regulate the flow of vital energy, tendon spleen, drying dampness to eliminate phlegm effect.Be used for fullness in the epigastrium and chest, the depressed cough ant phlegm of heating installation vomiting diet etc.

Chemical constituent: mainly contain hesperetin, contain limonene etc. in hesperidin, the Pericarpium Citri Reticulatae volatile oil, other contains organic base adrianol and Citrus aurantium Linn. haze wax element etc.

Pharmacological action: 1, antibiotic, antiviral, Pericarpium Citri Reticulatae can suppress the how blood bacteria growing had a liking for of Salmonella, hemolytic of staphylococcus, mucositis in vitro.Hesperidin has the effect that the protection cell does not receive virus infraction and resisiting influenza virus.

2, raise immunity: zoopery confirms; Pericarpium Citri Reticulatae is separated titre to GPS lysozyme content, serum coagulation antibody; Painstaking effort T lymphocyte E rosette forming rate all has remarkable potentiation; Explain that Pericarpium Citri Reticulatae all has certain facilitation to humoral immunization and cellular immunization, but lymphocyte transformation there is the obvious suppression effect to T.

3, eliminating phlegm and relieving asthma: the bright decoct of tasting with discrimination of Pericarpium Citri tangerinae is given rabbit trachea stream, and perfusion flow velocity at night is fast a little, like bronchus is had dilating effect.The Pericarpium Citri tangerinae alcohol extract can shrink the nearly spasm of the guinea pig in vitro bronchus due to the antihistaminic, and volatile oil and limonene have zest effect such as eliminate the phlegm.

5, antiinflammatory antiallergic: mouse peritoneal injection hesperidin has the antagonism kistrin, and LYSOLECITHIN SUNLECITHIN A, histamine increase the effect of vascular permeability, give the oral hesperidin of rabbit, and ear's cold injury that ethyl chloride is caused has the effect of mitigation symptoms.Hesperidin also has inhibitory action to the inflammatory reaction of rat Fructus Crotonis oleogranuloma capsule.

6, facilitating digestion: volatile oil has gentle stimulation to gastrointestinal tract, promotes secretion of digestive juice such as saliva, gastric juice, facilitating digestion, and can impel and discharge the enteral pneumatosis.

7, protection gastric mucosa: methylhesperidin 100---the continuous skin of 500mg/kg is annotated 6 days or disposable injection, can obviously suppress the generation of gastric ulcer due to the pylorus ligation, and potentiation is arranged with vitamin C, when vitamin K share, and is oral also effective.Xin Feilin in the Pericarpium Citri Reticulatae brings out the gastric mucosa damage to platelet activating factor has protective effect.

8, antitumor: experiment shows that limonene proves that to 4 kinds of human solid tumors' tissue culture it has anti-tumor activity, has the people from quintessence oil, to isolate Citrus aurantium Linn. haze wax element, and to the laboratory animal skin carcinoma, oral cancer colorectal cancer etc. has inhibitory action.Citrus aurantium Linn. haze wax element also has the inhibition effect to nearly anus place rectum position corpus carcinosus.

(7) 8 kinds of essential amino acids (amino acids) aminoacid is human body, biogenic base substance, also is the important component that constitutes human body.Human body is actually amino acid whose needs proteinic needs.

Aminoacid is participated in growth promoter and metabolic each process in human body; Keep the generation of growth promoter with cell, histoorgan, internal organs, blood, immune system and the skeletal muscle of repairing damage of histoorgan; And supplying nutrients and energy, synthetic important biochemical substances.That is to say do not have life without aminoacid.World health group (WHO) is classified aminoacid as the life essential first element for a long time, and biological educational circles is called as human body gold.Particularly human body self can not synthetic 8 kinds of essential amino acids: lysine, phenylalanine, methionine, leucine, isoleucine, threonine, tryptophan, valine, these 8 kinds of essential amino acids are healthy very important to human body.Scientific research confirms, will cause physically differently if human body lacks any aminoacid, influences that antibody is metabolic normally to carry out and body growth and health.

The physiological function of 8 kinds of essential amino acids:

1, lysine: (lysine), lysine is alkaline essential amino acids.Because lysine content is very low in the cereal foods, and in the course of processing, is prone to be destroyed and lacks, so be referred to as first essential amino acids.Lysine is essential amino acids very important in the construction human body protein, can promote growth promoter, organizes slender and generation antibody, hormone and enzyme.Lysine can stimulate the secretion of pepsin and gastric acid, plays the enhancement diet, promotes physical growth of children to grow.Lysine can also improve the absorption of calcium and accumulation in vivo thereof, quickens bone growth, and lysine can also improve attention and make the fatty acid of making energy can be by normal utilization in addition.As lack lysine, and can cause gastric secretion not enough and anorexia, nutritional anemia occur, cause that nervus centralis is obstructed, dysplasia etc.

2, phenylalanine (phenylalanine) phenylalanine is a kind of essential amino acids; Also be as the necessary aminoacid of nerve conduction; It is the chemical substance of coming and going between conduction brain and the neurocyte; In human body, can change noradrenalin and dopamine into, epinephrine and dopamine are the main neurotransmitter that improves habit ability and memory, and the two all belongs to the conductor of stimulation; But play the part of important role in high-level nerve conduction stimulation and change cerebral activity, also can improve the sensitivity and the vigor of health.Phenylalanine can also increase psychological Vigilance, appetite-suppressing, raise libido, and improves memory and improves the agility of thinking, eliminates depressive emotion etc.

3, methionine (methionine), methionine is the sulfur-bearing essential amino acids, and is closely related with the metabolism of various sulfur-containing compounds in the organism.In some schizophrenia of treatment, methionine helps to reduce the content of histamine in the blood, and the information that brain transmits mistake can cause in histamine here.Methionine capable of using with methyl, Toxic or medicine are methylated and play Detoxication.Therefore, methionine can be used for preventing and treating chronic or acute hepatitis, and hepatic disease such as liver cirrhosis also can be used for cushioning the toxic reaction of harmful substances such as arsenic, chloroform, carbon tetrachloride, benzene, pyridine and quinoline.Methionine and choline and folic acid combine and can prevent the formation of some tumor in addition.When lacking methionine, can cause loss of appetite, growth slows down or loses weight, and phenomenons such as kidney enlargement and the accumulation of liver ferrum cause hepatic necrosis or fibrosis at last.

4, tryptophan (Tryptophan), tryptophan are that a kind of ability is regulated the neural a kind of essential amino acids that helps for sleep.It and vitamin B6, nicotinic acid and magnesium act in brain together, make the compound ammonia in the blood, as brain and a kind of nerve conduction that information is come and gone between the biochemical mechanism of sleeping.Help lend some impetus to sleep, lower sensitivity, alleviate migraine, alleviate the symptom that chemical reaction is lacked of proper care in the human body that causes because of ethanol, and help control, gastric mucosal protection agent and the strong anti-agent etc. of going into a coma headache.

5, valine (Valine), leucine (Leucine), isoleucine (Isoleucine), threonine (Threonine).Valine, leucine and isoleucine all belong to branched-chain amino acid, all are essential amino acids simultaneously.Medically use the diseases such as injection for treating liver failure of branched-chain amino acid such as valine always, also be used to accelerate the wound healing therapeutic agent.Leucine can be used for diagnosis and the sudden hyperglycemia of children's and is used as dizzy treatment and nutritional tonics.Isoleucine can be treated neurological disorder, loss of appetite and anemia, and is also very important in the muscle protein metabolism.Threonine is participated in lipid metabolism, occurs fat lesion when lacking threonine.

(8) arginine (Arginine); Arginine is the amino aminoacid of a pair of; Be constituent in the ornithine circulation; Behaviour concrete conditions in the establishment of a specific crime essential amino acids also is to keep hypophysis normal function essential amino acids, and arginine is the precursor substance that an ammonification carbon, creatine, phenylalanine, glutamate, Glu etc. have important physiological function.Because arginine is described as star molecule carbon monoxide (NO) and precursor in life sciences, thereby more causes the concern of medical circle.Recent study finds that arginine health care aspect has extremely important physiological function.

Physiological function: 1, raise immunity: research shows that arginine has material impact to immune system.Arginic immune regulation mechanism and its metabolite carbon monoxide (NO) be in close relations to have regulating action; Carbon monoxide can weaken the ability of sticking of polymorphonuclear granulocyte (PMN); Enhanced natural is killed and wounded (NK) cytoactive; Activate the dried nucleus of peripheral blood, mediation minister phagocyte apoptosis, the carbon monoxide of low dosage has the mitotic effect of individual lymphocyte.Clinical research shows that additional arginine can strengthen cell property while still alive, gives before the art to strengthen EA before the arginine, can obviously reduce disease rate and mortality rate after being ill such as serious bad patient's postoperative infection.

According to another report,, promote the growth of thymus medium-sized lymphocyte, reduce the rate of transform of tumor, strengthen the phagocyte vigor though arginine can increase the weight of thymus, thus enhancing body's immunological function.

2, promote bone growth; Arginine can promote protein and growth hormone secretion, have the child of promotion bone growth and development, and the people of being of short and small stature " HPG " system negative and positive centre accent gets muddled control system; Growth hormone secretion reduces, and is the closed too early and termination of skeleton.Research shows that arginine can stimulate the pituitary secretion growth hormone, and other aminoacid are got in the skeletal muscle, promotes the skeleton hematopoietic stem cell, cell is generated increase, and improves the required blood oxygen of growth promoter, and skeletal cartilage cell division speed is obviously accelerated.Therefore, arginine can promote bone growth.

3, strengthen intramuscular tissue and reparation: arginine ability enhance muscle tissue; Accelerating wound healing helps repair tissue, and arginine can also be strengthened the connective tissue between tendon and the ligament, makes it more healthy; The protein synthesis that enhance muscle is long-living lowers content of urea in blood and the urine.Arginine is extremely important in muscle metabolism, and it makes annotates carrier defeated and storage oxygen, and helps the ammonia of peroxide to discharge.

4, memory reinforcing: it is reported that American Studies exists, arginine has the brain cell of adjusting flow, and the protection brain cell membrane is alleviated the brain tense situation, increases functions such as memory.Lack arginine person longterm memory, the note memory for a long time and the back of the body are educated ability and all can be weakened, even occur that brain is tired, the cerebral anoxia phenomenon, and therefore, arginine has the effect of memory reinforcing.

5, protect the liver: research shows that arginine can increase the activity of arginase in the liver, helps ammonia in the blood to change carbamide into and excretes.So arginine is to hyperammonemia, diseases such as liver malfunction have certain effect.According to another report, arginine in liver cirrhosis and fatty liver in the ability with excess of ammonia that liver produces, so can help liver to dispel toxin.

6, promote to hinder the article healing: the important metabolic function of arginine is to promote the wound healing effect, and it can promote collagen tissue synthetic, so can repair wound.In the wound juice, can be observed the active rising of arginase, this shows that also near the arginine requirement the wound heightens.Arginine can promote the microcirculation of wound circumference and wound is fully recovered early.

7, suppress tumor: additional arginine can reduce the volume of tumor animal, reduces the neoplasm metastasis rate, improves time-to-live and the survival rate of animal.In immune system, except that lymphocyte, cytophagous vigor is also relevant with smart oxygen acid, strengthen smart oxygen acid after, but its system of activation, making it more can the kill tumor cell and target cell such as antibacterial.

In addition, arginine also has antifatigue effect.

(9) glutamic acid (GIU); Glutamic acid is the highest a kind of free amino acid of brain intensive amount; Higher 200 times than the concentration in other blood plasma, also be body the most effectively, one of the abundantest oxygen source, in amino acid metabolism, occupy critical role; And the participation cerebral tissue has metabolism, correction brain cell growth defect.It is former to be situated between as the nerve excitability amino acid neurotransmitters, participates in a series of higher nervous activities.

Physiological function: 1, prevent and treat osteoporosis: it is reported that current research of Japan finds that glutamic acid has the effect that osteoclast is decomposed osseous tissue that suppresses.Therefore help to prevent and treat osteoporosis.In vivo, have osteoclast of decomposing sclerotin and the osteoblast that forms skeleton, under the normal condition, these two kinds of cells keep balance.If balance is broken, osteoclast is too active, can cause taking place osteoporosis.Experiment is found, the receptors bind that glutamic acid can be surperficial with osteoclast, and enzyme in the active cell suppresses osteoclast and decomposes sclerotin.Therefore, glutamic acid can prevent and treat osteoporosis.

2, correct the biochemical defect of brain cell: glutamic acid is the main excitatory neurotransmitter of cone neurone, can combine with corresponding excitatory amino acid receptor, has important effect at aspects such as study, memory, neural plasticity and brain developments.Glutamic acid can enliven cerebral function, and exciting sympathetic nerves is improved cerebral metabolism, corrects the brain cell defective, has important function to promoting memory and children ' s intelligence development.Research thinks that the temporary transient neural formation generation obstacle that connects of Learning and Memory maybe be relevant with the reduction of glutamic acid level in the brain hemisphere.According to another report, be the release of glutamic acid in the cell at the beginning of study, a series of subsequently activities cause synapse straight through increase, and the accelerator nerve mediator transmits, thereby helps the acquisition of behavior, thereby glutamic acid has been participated in the learning and memory process directly.In addition, glutamic acid ability absorbed nitrogen atom is removed the toxin of ammonia, and this is the toxic method of the most important releasing of brain.

(10) cysteine (Cysteine) cysteine is a kind of aliphatic polarity a-amino acid that contains sulfenyl, also is the protein synthesis coded amino acid, can be transformed by intravital methionine (methylthio-aminoacids of needed by human), can transform mutually with cystine.Cysteine is to belong to non essential amino acid, is in animal body to be synthesized through cystathionie by methionine and serine.

Cysteine has many physiological actions, can alleviate the degree of intoxication of Toxic or toxic medicament, and radiation is also had prevention effect, cysteine derivative N-acetyl-L-cysteine, the discharge difficulty that can be used for preventing and treating cough with asthma such as bronchitis.The light cystine also has beauty treatment, promotes hair growth, treats functions such as alopecia, heart body depletion, bronchitis in addition.

Physiological function: 1, separate the ethanol hepatoprotective: cysteine has the effect that absorbs ethanol, and it is converted into the de-inebriating effect of acetaldehyde in vivo.Cysteine can also significantly reduce the concentration of ethanol in blood; Improve pathobolism that ethanol causes, promote ethanol to decompose, eliminate over-drastic free radical; Hinder the formation of lipid peroxide; Thereby alleviate the damage of ethanol to hepatic tissue, the various diseases of avoiding alcoholism to cause various Developmental and Metabolic Disorder to be brought out has certain Detoxication to liver poisoning, antimony agent poisoning, radiopharmaceuticals poisoning.According to another report, cysteine has clathration etc. in vivo, thus to far-ranging poisonous substance such as formaldehyde, acetaldehyde, chlorine spin, carbon tetrachloride, lead, cadmium, chloromethane hydrargyrum, lipid peroxidation, PCB, tetrodotoxin, TTX, ethanol etc. have significant Detoxication.

2, sun-proof whitening: cysteine has sun-proof significantly, anti-ultraviolet function, and the protection cell membrane is not tanned severely, and prevents skin aging and pigmentation; Reducing melanin generates; Ultraviolet is the key factor that skin forms mottle, and brown matter fat peroxidating material also is one of reason.Research shows that cysteine can stop the activity that can bring out melanic precursor substance tryrosinase, can also suppress to generate lipid peroxide simultaneously, prevents the effect of brown patch.According to another report; Cysteine is kept the activity of important coloured glaze base enzyme in the keratin of skin protein generates; And additional coloured glaze base regulates the bottom melanin that the undermost pigment cell of epidermis generates keeping the homergy of skin, is a kind of very ideal natural skin-lightening cosmetic.Can also remove the melanin of skin itself in addition, change the character of skin itself, make the skin beauty of nature that becomes white.

3, antiinflammatory antiallergic: when coloured glaze base enzyme that inflammation, allergy make gallbladder phosphatase etc. occurring and reduce, cysteine can be kept coloured glaze base enzymatic activity, improves inflammation and skin symptom hypersensitive.

4, radioprotective: cysteine has significant radiation resistance, can effectively prevent and the injury of radiotherapy property.

In addition, take care of hair in addition beautiful, function in delaying senility of cysteine.

(11) glutamine (Glutamine) glutamine is a kind of neutral amino acid, is the abundantest a kind of free amino acid of content in the human plasma.

Glutamine is the carrier of urea synthesis ammonia in ammonia synthesis and the liver in the kidney, is the many important substance of cell amine scavenger and biosynthesis, like nucleic acid and amino acid whose coenosarc.Glutamine is synthetic at mediator's body protein as human body one seed amino acid; The degraded of CKIs matter; Stimulating cellular growth; The activate immunity function promotes hormone secretion, improves brain function, prevents alcoholism, functions such as the liver protecting, antidepressant, raising immunity, resisting fatigue, prevention muscle are aging, defying age, healing ulcer of digestive system play an important role.

Physiological function: 1, trophic function: though glutamine is a kind of non essential amino acid; In human body, can synthesize voluntarily; But the more seed amino acid of content in the human body as in muscle protein, accounting for 61% of total amino acid content, accounts for 20% of total free amino acid in blood plasma.Someone finds to be most appropriate in each seed amino acid of cell growth in cultivating the mammalian cell culture fluid, and glutamine is that requirement is the highest, visible its importance in hyperplasia.The carbochain skeleton of glutamine can be transformed into glucose in liver; The carbochain skeleton also can be provided and synthesize other aminoacid with a-amino acid; Glutamine then can be used as synthesizing ribonucleotide, and therefore the ammonia source of aminoacid and amine sugar is the basic boom unit of synthetic protein.Be amino acid whose means of transport in metabolic process, between organs such as kidney, liver, digestive tract, play the translation function of important ammonia, carbamide, ammonia etc.

2, improve brain function: glutamine has the effect that increases the brain cell function, can be used to treat neurasthenia, apoplexy sequela and dysmnesia, and can promote mental retardation child's intelligence development, and the prevention epilepsy is also had certain curative effect.

3, relieving alcoholism and protecting the liver: glutamine has the specific function of the liver protecting tissue.It can prevent because the fatty liver that excessive absorption carbohydrate causes can stimulate glucagon secretion, thereby reduces the plain ratio of tremulous pulse insulin/blood glucose, increases transporting of liver lipid.Glutamine also has a special function, and it can increase the content of ethanol dehydrogenase in the body, thereby decomposes ethanol fast, accelerates the decomposition of ethanol, treatment and prevention alcoholism, the liver protecting.

4, enhancing immunity: lymphocyte is rich in the high activity transglutaminase; When receiving immunostimulation, its enzymatic activity increases, and experiment shows; Glutamine can obviously be put forward the speed that is integrated into of thymus, pyrimidine, so glutamine is the essential material of lymphopoiesis.Discover that in addition glutamine has important function in whole host defense mechanism, and the immune system of reconstruction is arranged and improve anti-infection ability.

5, resisting fatigue: glutamine has unique function and nutritive peculiarity, so glutamine can be used for treating athlete's syndrome, recovery highly intensive labour and post exercise fatigue.Research confirms, glutamine is a rich in amino acid the most in muscle and the blood plasma, and it provides energy fast for leukocyte, and the while also is the important source material of synthesizing ribonucleotide.Exogenous additional glutamine helps to keep the concentration of the glutamine in athlete's normal blood, and can prevent the infringement of immunologic function behind the prolonged exercise, also has research to show that back 2 hours oral glutamine of marathon campaign can reduce athletic injury.

In addition, glutamine can also suppress diarrhoea, reduces electrolyte and loss of moist.

(12) aspartic acid (Aspartie aeid) aspartic acid is also claimed aspartic acid, is a kind of a-amino acid, and aspartic acid L-isomeric compound is one of a kind of gal4 amino acid.Be proteinic component unit, it and glutamic acid belong to acidic amino acid together, are the synthetic precursors of propylhomoserin such as lysine in the organism, threonine, isoleucine, methionine and purine, pyrimidine bases.Aspartic acid also is a kind of energy aminoacid, can be converted into glycogen rapidly in vivo, can in metabolism, become the aminoacid of sugar, also is excited aminoacid.Aspartic acid is the analeptic of nervus centralis, through with corresponding receptors, in conjunction with participating in the transmission of nervus centralis information, play an important role at learning and memory, synaptic plasticity and neurodevelopment.Aspartic acid can also be removed excess of ammonia in the blood, so can the liver protecting.Aspartic acid can also increase immunoglobulin and production of antibodies, also is the precursor substance raw material of synthetic orotic acid and nucleic acid.It can be used as potassium, the magnesium ion carrier is carried electrolyte to cardiac muscle, and the function thereby the change cardiac muscle contracts reduces oxygen consumption simultaneously, when coronary artery circulation, obstacle anoxia, cardiac muscle is had protective effect.Use after also often aspartic acid being processed the salt of calcium, magnesium, potassium and ferrum etc.; Because these metals play a role with getting in the cell through aorta transport pathway permeate through cell membranes after aspartic acid combines, be used for treating diseases such as heart disease, hepatopathy, diabetes clinically.Aspartic acid potassium salt and magnesium salt mixing are mainly used in allaying tiredness, and iron salt can be treated anemia.

(13) agedoite (Asparagine) pharmacological research, the agedoite intravenous injection can make blood pressure drops, the expansion peripheral blood vessel, mental and physical efforts are shunk and are strengthened, and heart speed slows down and the urine amount increases.The oral agedoite of pylorus ligation rat, the gastric mucosa injury that can stop oral acetylsalicylic acid to cause.Animal experiment shows that agedoite has significantly calm and certain antiasthmatic effect.According to another research, the propagation of different carcinoma cell need consume a large amount of certain specific aminoacid, seeks this amino acid whose analog---metabolism agent, is considered to treat a kind of effective means of cancer.Agedoite can prevention needs the propagation of the cancerous cell (leukemia) of agedoite.The analog S-carbamyl-cysteine of agedoite has obvious effects through animal experiment to leukemia, and the amino acids cancer therapy drug of having manufactured experimently at present has kind more than 10.

(14) proline (Proline), proline are a kind of cyclic imino acids, unique imino acid in common 20 seed amino acids of constitutive protein.Pyrrole ring is structurally closely related with hemoglobin in the proline molecule.Hydroxyproline is one of constituent of collagen.Intravital proline, hydroxyproline concentration imbalance can cause cartilage and the toughness of ligament tissue in tooth age, the skeleton to weaken.Proline derivative cooperates with diuretic, has anti-blood pressure.

Proline also is medical Branchamin, and one of amino acid infusion solutions raw material is used for malnutrition, and the protein behind hypoproteinosis, serious gastroenteropathy, scald and the surgical operation replenishes.

(15) histidine (histidine): histidine is a kind of alkalescence and polarity alpha amino acid that contains the imidazole radicals side chain, and histidine also is the coded amino acid and the glucogenic amino acid of protein synthesis.Histidine for non essential amino acid, but is an essential amino acids to the child to the adult.In chronic uremia patient's meals, add a spot of histidine, combine hemoglobin to increase sharply with aminoacid, kidney originality anemia alleviates, so histidine also is the essential amino acids of uremic patient.Imidazole radicals ability Fe2+ or other metal ions of histidine form coordination compound, promote the absorption of ferrum, thereby can be used for preventing and treating anemia.Histidine can reduce the degree of gastric juice, relaxes the pain of gastrointestinal procedures, alleviates trimester of pregnancy vomiting and stomach burning sensation, suppresses nervous by vegetative nerve and digestive tract that cause festers, and is to anaphylactic disease, also powerful like asthma etc.In addition the expansible blood vessel of histidine, bring high blood pressure down, be used for treatment of diseases such as angina pectoris, cardiac insufficiency clinically.Histidine content significantly reduces in the rheumatoid arthritis patients blood, finds its grip after using histidine, walks and index such as erythrocyte sedimentation rate all take a favorable turn.Under the effect of HDC E.C. 4.1.1.22, the histidine decarboxylation forms histamine, and histamine has very strong vasorelaxation action, and with multiple allergy and take place relevant.

(16) glycine (Glycine) glycine is the simplest natural amino acid; Also be the minimum aminoacid of molecular weight in the aminoacid; Glycine is the human body non essential amino acid, can be changed by glucose in vivo, thereby unique sweet taste is arranged; Glycine can combine with miscellaneous material, makes it by discharging in bile and the urine.Glycine can provide the ammonia source of non essential amino acid, improves amino acid injection toleration in vivo.Glycine used with glutamic acid, alanine can prevent the prostate hyperplasia complication, symptoms such as dysuria, pollakiuria, residual urine produce effect frequently.

Physiological function: 1, antibacterial: can stop bacterial growths such as bacillus subtilis, escherichia coli, staphylococcus aureus, bacillus flavus, Bacillus licheniformis during glycine 2% concentration.

2, improve sleep: research shows, gives 14 male and 15 women in 3 gram glycine for oral administration just before going to bed, and brain wave shows the rapid speed that gets into deep sleep, and prolong the length of one's sleep, suffers from the respond well of second day allaying tiredness of insomnia person.Find have to accumulate in brain pinus phenomenon on every side through rat experiment.

(17) serine (serine), serine also is a ketogenic amino acid, is a kind of aliphatic polarity alpha amino acid, serine is common 20 seed amino acids a kind of of constitutive protein matter, is purine biosynthesis, the precursor of thymus pyrimidine and choline.

Serine is a kind of non essential amino acid, and it is being brought into play in fat and the metabolism of fatty acid and muscle growth and is acting on, because it helps immunoglobulin and production of antibodies, the immune system of keeping health also needs serine.Serine is all being brought into play in manufacturing processing, muscular tissue and the encirclement neurocyte sheath of cell membrane synthetic and is being acted on.

Phosphatidylserine (PS) is the chemical compound of synthetic serine in human body.The Phosphatidylserine supplement can increase neurotransmitter acetylcholine in the cerebral cortex, acetylcholine and thinking, and reasoning and attention are concentrated relevant.Phosphatidylserine also is to stimulate the synthetic of dopamine and discharge.Phosphatidylserine seems and brain and relevant to the reaction of pressure, and a clinical research finds that in the experiment of exerting pressure to healthy subjects, the people who takes Phosphatidylserine is lower than other crowds to the reaction of pressure.The thyroliberin level draws stress reaction in the blood through weighing.Thyroliberin is that it promotes acth secretion stress hormone hydrocortisone thereupon by the oozy a kind of hormone of hypophysis.Phosphatidylserine is mainly used in treatment dementia (dementia that comprises Alzheimer disease and Fei Azihaimo) and normal old memory loss.

(18) alanine (alanine), alanine are a kind of aliphatic nonpolar amino acids, and common L-a-amino acid is one of protein coding aminoacid, makes human body non essential amino acid and glucogenic amino acid.The D-alanine is present in the Peptidoglycan of various bacteria cell wall.Alanine plays an important role to body internal protein building-up process, it in vivo metabolism generate keto acid through deamination, generate sugar according to the glucose metabolism approach.Alanine has anti-very by force renal calculus, assists glucose metabolism, helps mitigation hypoglycemia, improves body energy.

(19) glutathion (GSH) glutathion is a kind of active kyrine with important physiological function.Be by glutamic acid, cysteine and glycine through the tripeptide compound that the peptide bond condensation forms, be broad-spectrum bioactive peptide.Glutathion two molecule reduced glutathiones (GSH) and active sulfenyl oxidative condensation are disulfide bond, promptly obtain oxidized glutathione (GSSH), but have only just biologically active of reduced glutathion.Scientific research thinks that glutathion has antioxidation, removes free radical, alcoholic intoxication hepatoprotective, enhancing immunity, beauty treatment are sun-proof, speckle dispelling, radioprotective, slow down aging, function such as anticancer.

Physiological function: 1, remove free radical, antioxidation: glutathion contains active SH, can be with the H of metabolism of human cell generation ₂O ₂Be reduced into H ₂O removes free radical.Free radical meeting damaging cells film, promotion body aging, and bring out cancer and arteriosclerosis.Glutathion has the free radical of removing and antioxidative effect.To the hydrogen peroxide that produces in the body, hydroperoxides and lipid oxide generate free radical all has scavenging action.Glutathion can be protected cell membrane and cell function through antioxidation, and delaying cell aging prevent the reduction of erythrocyte hemolysis and promotion metahemoglobin, so glutathion has anti-human body cell peroxidation.

2, Detoxication: glutathion has the broad-spectrum Detoxication; To the body toxic compounds; Like poisonings such as acrylonitrile, fluoride, carbon monoxide, heavy metal, organic solvent, alcoholism, carcinogen certain Detoxication is arranged all; Can combine with it and promote to excrete, also can be used for the treatment that above-mentioned substance is poisoned, therefore have Detoxication.Thereby protect us not receive the infringement of vehicle exhaust carcinogen, infectious disease, excessive alcohol and poisonous element, according to another report, glutathion has the alcoholic intoxication liver protection effect; It can improve the Developmental and Metabolic Disorder that ethanol causes; Can protect gastric mucosa to avoid alcoholic acid injury, strengthen liver detoxification function, thus effectively prevent drunk appearance headache, vomiting, feel sick and symptom such as be drunk overnight; Also can protect and repair hepatocyte and accelerate the metabolism of liver to poisonous substance, antagonism ethanol acetaldehyde is to liver and infringement.

3, the liver protecting: liver is glutathione content the abundantest the highest organ in the human body; The critical function of liver is Detoxication; When glutathion is on the low side in the liver, can cause the toxicant metabolism to descend, can't discharge the injury that the vivotoxin material causes liver function.Like the chronic alcoholism patient, mitochondrial glutathione content is crossed the active oxygen that hangs down in metabolic process to be produced and can't be neutralized by glutathion in its hepatocyte, thereby can cause the disease such as death and liver cirrhosis of cell.Suitably replenish the recovery that glutathion helps liver function, also can suppress the formation of alcoholic fatty liver, hepatoprotective.

4, protection leukocyte: glutathion is to lonizing radiation, and the leukopenia that radiopharmaceutical and antitumor drug cause has very strong protective effect, can be used for the auxiliary treatment of tumor chemoradiotherapy.

5, alleviate old age from the beginning of being afraid of golden gloomy disease: Parkinson's disease is a kind of neurodegenerative disease; The origin cause of formation that it is generally acknowledged Parkinson's disease is relevant with the degeneration of substantia nigra of midbrain district compact part; This zone has the function of producing with metabolism nerve conduction material dopamine in brain; Can produce many active oxygens, particularly hydrogen peroxide during the dopamine metabolism, it can be converted into nontoxic water by glutathion.But when glutathion was not enough, active oxygen will be attacked neurocyte and cause its death, and then produced neurodegenerative disease.Therefore glutathion is relevant with the generation of Parkinson's disease, has human intravenous injection glutathion at present and alleviates Parkinson's disease and obtain certain effect.

6, spot-eliminating beauty treatment: glutathion can suppress the activity that melanin generates enzyme, prevents skin aging and pigmentation, reduces melanic formation, improves the skin oxidation resistance, and makes generation gloss, prevents the deposition of melanin at face.

7, antiallergic: research shows that glutathion can be treated human body by acetylcholine, and the unbalance allergy that causes of cholinesterase has antianaphylactic effect.

Glutathion can also be treated disease of eye such as senile cataract in addition.

(20) carnosine (oarnosine), carnosine are the natural anti-oxidation materials that is present in the animal muscle, also are a kind of bioactive peptide with important physiological function, the active dipeptides that Beta-alanine and histidine are formed, and its function and usage is extensive.Carnosine is the dipeptide active substance that contains histidine; Have functions such as antioxygen property, protecting film integrity, sequestration metal ion, proton buffering, adjusting macrophage activity because of it; Be considered to have leading ischemia resisting damage medicine, research thinks that carnosine has protective effect to the IRI of kidney, heart, liver, brain.

Physiological function: 1, protected protein matter: research shows; Cause a major reason of human senility to make the variation of human body internal protein; But because a kind ofly in the body be called that glycosylated chemical reaction causes, the people when old nearly 1/3 protein by glycosylation.Research confirms that carnosine is a kind of Natural antioxidant, can combine with proteinic carbon-based group, is that protein is not easy to take place interconnection, thus protected protein matter.

2, antioxidation: research shows that carnosine is a kind of powerful antioxidant, has tangible anti-radical action, and carnosine can also strengthen other antioxidant simultaneously, like the effect of vitamin E and superoxide dismutase (SOD).Evidence does not up to now also have a kind of effect that can play the protection telomere as carnosine in various antioxidants.

3, slow down aging: carnosine has multiple senile-resistant efficacy.Discover that the proteinic degeneration of the most important component of organization of human body is the major reason that causes human senility.Carnosine has the important function of anti-protein degeneration, and long health life-prolonging secret is exactly that body muscular tissue contains a large amount of carnosines.Research also finds, carnosine can recover some also has the effect of uniqueness with the activity of senile cell and protection gene.The telomere of human senility and cell chromosome shortens also has substantial connection.The people with advancing age and telomere will shorten gradually, and is slowly ineffective, finally causes cell death.Carnosine can also be engulfed too much heavy metal ion chemical compound in addition, makes it to lose activity.Carnosine also has buffering effect, can prevent and allaying tiredness, increases respiratory capacity, improves effects such as sleep.

4, sexual function improving: research confirms that carnosine can be regulated the oxidation ammonia level in the blood, and that nitric oxide has the penis of a making smooth muscle is loose, small artery vasodilation with increase the penile blood circulation, impel erection.And viagra is brought into play promotion erection through regulating nitric oxide.In addition, carnosine also has human body to the potential effect of hormone response level.

5, anti-senile dementia: carnosine has the effect of control senile dementia.The function of carnosine ability hypermnesis and neurotransmitter, the information in the brain that helps is transformed into another neurocyte from neurocyte.Zinc and copper can stimulate the generation amyloid-beta.Discover that β-starch albumen is a kind of noxious substance, it can cause the over-drastic metabolism of brain cell, quickens brain cell death, increases the weight of the infringement that free radical causes, suppresses the normal growth damage cerebral blood vessel of cell.And carnosine can combine the damage of common antagonism amyloid-beta to brain cell with zinc and copper ion.Experiment shows that carnosine is the strongest at the protection brain cell.In addition, carnosine can also intensify sodium in the brain, potassium and energy matter ATP, and the protection brain does not receive the attack of free radical, increases the blood flow in the brain, reduces the side effect that brain produces, and safeguards the cerebral metabolism balance.Research finds that also carnosine can reduce the content of glycosylation terminal product, reduces other toxic compounds and generates.Therefore carnosine can not only antioxidation with prevent glycosylation, can also prevent and treat the old and feeble mechanism that chronic inflammatory disease causes.

6, to resisting hypertension: research shows that glycosylation can cause vessel wall thickening, finally causes hypertension.Carnosine can alleviate the damage of glycosylation to blood vessel wall, therefore has antihypertensive function.Carnosine is the nitric oxide level in the scalable blood also.Nitric oxide can be fitted slow blood vessel when an amount of, play hypotensive activity.

7, anticoagulation and hemostasis: research shows that platelet plays an important role in hemostasis.If for a certain reason, make flocking together of hyperthrombocytemia, will be that blood forms bulk, thereby cause obstruction of artery.If in the time of the needs hemostatic, platelet is but assembled slowly, can cause hemorrhage again.Carnosine has the effect that platelet aggregation was regulated and controlled to double-bang firecracker.Not smooth to blood circulation, carnosine can anticoagulant, the apoplexy that anti-tampon causes.And prevent hemorrhage through the platelet increasing gathering to the normal people of hemorrhage meaning.

8, anti-curing arthritis, promotion bone health: it is reported; The Japan expert discovers; Carnosine one zinc compound is to suffering from rheumatic arthritis and postmenopausal women is treated discovery, and the pain that carnosine can the ameliorate osteoarthritis patient is strengthened knee joint structure; The osseous tissue that the stimulating osteoblast structure is new has conventional antarthritic effect.

9, anticancer: it is reported that the carnosine of Russian clinical use high dose is treated inoperable tumor and overcome the radiotherapy chemotherapy side effect, experiment shows that existing short-term has secular good result again.Because cancerous cell needs sugar to provide energy keeping growth, thus quicken the consumption of sugar, and carnosine can reduce the supply of sugar, therefore has the potential ability of cancerous cell hungry to death.Leukocytic quantity usually can reduce after radiotherapy or chemotherapy, and carnosine can stabilizing cell membrane, and pair cell has protective effect.

10, antiulcer: carnosine can stimulate the new epithelium in gastric ulcer position to generate.Be used to treat the harmonization of the stomach duodenal ulcer in Japan's official approval.

11, promote wound healing: carnosine can promote wound healing, is applied to the oral medicine of surgical operation therapy especially.

In addition, carnosine also has the effect of cataract of preventing and treating and diabetes.

(21) Tibet sheep placental extract (sheep ' s), (Placenta caprae seu ovis extract).Be conceived 3-5 month sheep embryo of tibetan sheep, utilize biotechnology to extract biological activity.China's tradition Chinese medicine is used history for a long time to the animal Placenta Hominis.According to Compendium of Materia Medica record, warm in nature, the sweet-salty of sheep placental extract.Effect with the kidney invigorating, replenishing essence, benefiting qi and nourishing blood.The clinical men and women's of being used for asthenia, neurasthenia, QI and blood deficiency, spiritlessness and weakness, prolonged illness loss, spontaneous sweating, sexual disorder and endocrine disturbance are caused a disease all effective in cure.The traditional Chinese medical science is thought has QI invigorating, nourish blood, replenishing vital essence function.Be used for sexual impotence, seminal emission, women's insufficiency of vital energy and blood and infertile, hypogalactia etc.Modern medicine study; Sheep placental extract is a kind of polypeptide protein material or perhaps the living cells thing that from conceived Placenta caprae seu ovis, extracts; But this material activating human body skin and trachea function; Effectively promote body metabolism, enhancing human body immunity power, promote human tissue cell's division, cell activity enhancing, reinforcement Skin Cell regeneration capacity, speckle dispelling, wrinkle-chasing, enhancing skin elasticity and gloss, delay youth, skin whitening, defying age, relieving mental strain and helping sleep, improve memory, allaying tiredness etc.

Chemical analysis: 1, steroid hormone: have that multiple steroid is bright, an androsterone, estradiol, estriol, estrone.2, placental hormone: GTH A, GTH B, prolactin antagonist, thyrotropin, chorionic-gonadotropin hormone, thyroliberin etc.3, enzyme: kininase oxytocinase, lysozyme, ball egg folding enzyme, hyaluronidase etc. are arranged.Contain DNA and nucleic acid, polypeptide protein, ten several amino acids, mucopolysaccharide, lecithin, B.Vitamin etc.Can produce various adjusting peptides, somatomedin, cytokine, nucleic acid etc. rapidly according to external report sheep placental extract, and the active factors with superpower dna replication dna ability.

Pharmacological action: 1, antioxidation: sheep placental extract was to 20 months healthy geriatric rat 150mg/kg every day body weight; 300mg/kg, 600mg/kg per os award sheep placental extract solution; After 80 days, measure respectively and respectively organize superoxide dismutase (SOD), malonaldehyde (MDA), monoamine oxidase, MAO (MAO) in rat erythrocyte and the tissue.The sheep placental extract SOD content in the old rats erythrocyte that can obviously raise as a result reduces MAD content in serum and the hepatic tissue, and reduction cerebral tissue MAO vigor, so sheep placental extract has antioxidation to old rats.

It is reported that the foreign study experiment shows that (1) fruit bat average life increases by 17.7%, human body is taken 15 days experimenter's lipid peroxides and is descended, and superoxide dismutase (SOD) value rises, and explaining has positive effect to human body MDA (malonaldehyde), SOD.(2) rat blood serum and liver MDA descend 15%, and lipid oxide is had inhibitory action.(3) rat blood serum SOD raises 9.63%, and the manganese antioxidase raises 33.13%.

2, defying age: sheep placental extract has irritation cell regeneration capacity, slow down aging.It is reported that embryonic stem cell that sheep placental extract and umbilical cord contain and adult stem cell, these active component have face nourishing antidebilitation and act on always.

3, enhancing immunity; Research shows; Sheep placental extract compares mice nonspecific immunity and specific immune function index analysis; The phagocytic function of the thymus of sheep placental extract high dose group, low dose group, index and spleen index and mononuclear phagocyte all obviously improves; The conversion reaction of splenocyte strengthens, and serum hemolysin generation value also increases, so think that sheep placental extract has the effect that improves the mice body's immunity.

4, endocrine regulation: sheep placental extract has obvious effects to regulating the hormone secretion function, can improve human body hormone secretion level, and the delaying female ovary is old and feeble, change the ovary function, prevent climacteric obstacle, physiological change.

5, looks improving and the skin nourishing: research shows that contain a series of micromolecule polypeptides such as peculiar superpower biological activity SF and BF in the sheep placental extract, its relative molecular weight is 3800-5000; It can activate Skin Cell regeneration, makes it to breed degree of progress speed, activation skin surface tissue; Removing also stops harmful oxide to be accumulated and melanocyte formation melanosome, and mottle can't be formed, and keeps skin-whitening; Promote the elastin laminin cell proliferation, make the skin reticular fiber structure become closely flexible, keep moisture of skin to be difficult for running off and replenish skin-nourishing, balancing skin metabolism comprehensively; Eliminate pachylosis, dry and cracked phenomenon, make skin become tender and lovely.Therefore sheep placental extract has just enjoyed the women to welcome since coming out.

6, smooth away wrinkles: sheep placental extract can promote the elastin laminin cell proliferation, makes the skin reticular fiber structure become closely flexible, makes moisture be difficult for running off, and replenishes skin-nourishing comprehensively.According to another report, the loose corrugated reason of the skin influence that is free radical.Sheep placental extract has the effect of oxidation and removing free radicals, can dispel facial wrinkles.

7, promote hemopoietic, improve anemia: research thinks, sheep placental extract can hemopoietic tissue, promotion hemopoietic has tangible anti-anemia effect, the effect of rising erythrocyte significantly promotes the bone marrow hematogenesis function, improves the asthenia universalis symptom.

8, smooth away wrinkles: Foetus Caprae seu Ovis have nourish blood, invigorate blood circulation, regulating menoxenias such as removing heat from blood and blood, can make blood engorgement skin, be that skin obtains enough nutrition, can effectively dispel wrinkle and delay wrinkle and produce too early.

9, gonadotropic Effect: sheep placental extract can promote the growth of women's secondary sex characteristics, promotes that endometrial hyperplasia is beneficial to embryo nidation and growth.According to another report, sheep placental extract is given children rabbit injection age of sucking, has the effect that promotes its growth, can significantly promote the growth of thymus, spleen, uterus, vagina, mammary gland; Thyroid, testis also there is the growth of promotion effect.

(22) zinc (Zn), zinc are the trace element that body weight for humans is wanted.Mainly be present in skeleton, tooth, testis, the adrenal gland, skin, in the organ pipes such as muscle, especially with retina, choroid, prostate is for the highest.Zinc relates to each aspect of organism intracellular metabolite, comprises transcribing and duplicating of hereditary material, and is closely related with health and disease.Zinc still is the cofactors of 100 plurality of enzymes, also is protein, the constituent of hormone and nucleotide.Zinc is the trace element of needed by human, and it plays important effect to human life and health.Zinc and metabolism, growth promoter and other different physiological roles are in close relations, particularly keep male reproductive system normal configuration and sexual function and have important effect.

Physiological function: 1, promotion property organ pipe and sexual function are grown, and zinc can guarantee secondary characteristic of male and the growth of female reproduction phase.The human body zinc deficiency can make hypophysis cerebri discharge the GTH minimizing, causes sexual maturity to delay, the gonad atrophy, and hypogonadism, to the growth of people's spermatogenic cell, the adjusting of reproductive function also has great importance.The intravital zinc content of people mainly is distributed in testis, epididymis and prostate and seminal fluid; Especially the highest with zinc content in the seminal fluid, zinc gets into sperm in a large number before spermioteleosis, both guaranteed the generation of sperm; Also keep the normal condition of seminal fluid source epithelium; So what of zinc content in the seminal fluid influence the key factor of sperm quantity and quality most, thereby promotion property organ pipe and gonad development.

2, promote hormone secretion: zinc all has effect in the generation of some testosterone in storage and the secretion, to the reaction generation significant impact of receptor usefulness and target cell.Zinc and reproductive system metabolic activity are closely related, and it can keep normal sexual function, to the growth of people's spermatogenic cell, maturation.Activate with function course and also participate in directly.Zinc content for a long time, the spermatogenesis ability is active, during zinc deficiency, testis dwindles, sperm number reduces, testosterone levels descends, sexual hypofunction.

3, sexual function improving: zinc and reproductive physiology and sexual function relation are very close.It can keep normal sexual function, and to the growth of people's spermatogenic cell, maturation activates with function and also participates in directly.Have enough zinc could guarantee to be highly sexed in the human body, sexual function and reproductive performance are just healthy.Zinc deficiency can cause motility of sperm to descend, sexual hypofunction, and zinc deficiency also can cause impotence.

It is reported that zinc is the androgen---the metabolism necessary of testosterone, can protect health reactance pressure, raising property interest.In addition, zinc has obvious effect to the sexual disorder that prostatauxe, prostatitis cause.

4, delay is old and feeble: zinc can the activity function, makes sex hormone secretion in vivo keep normal.Zinc deficiency descends sex hormone level, and genitals generation degeneration changes, and sexual function is significantly descended, and causes impotence, causes low sperm activity.Cause impotence, cause low sperm activity.It is the old and feeble main symbol of property that gonadal hormone reduces, and gonadal hormone significantly reduces in the body, and body can be aging rapidly, so the timely zinc supplement of old people is the old and feeble important means of delay.

5, defying age: zinc is a kind of important antioxidants, can improve the activity of body 200 plurality of enzymes, and enhancing body is removed ability freely; Thereby effectively postpone biomembranous 26S Proteasome Structure and Function, and participate in the reproduction process of cell, therefore; The aging course of zinc deferrable cell, the life-span of prolongation cell.According to another report, zinc is numerous protein, and the composition of nucleic acid synzyme can promote cell to upgrade, and can strengthen to exempt from tired function and cerebrovascular atherosclerosis has substantial connection.Zinc deficiency can influence brain function, Hippocampus function especially, the formation of Hippocampus function participation in learning, memory, emotion and trained reflex.Therefore, but the zinc memory reinforcing delays brain aging.

6, control is sterile: the reason that causes infertility is numerous, has found that under study for action the zinc element in the seminal fluid has significant impact to fertility.For example zinc can stimulate sperm to breathe, and promotes motility of sperm, also has the effect of anti-pathogenic microorganism.The protection sperm is avoided invasion and attack, keeps sperm membrane stability and integrity, and prevents that sperm from disintegrating too early, utilize with ovary combine the increase chance of becoming pregnant.With after the zinc treatment, sperm number is increased clinically, vigor improves, and recovers fertility.

7, enhancing immunity: zinc and immunologic function relation are very close.It participates in cellular immunization and humoral immunization process directly.Zinc has the effect that promotes lymphopoiesis and movable function, to keeping epithelial tissue with mucous membrane tissue is normal, the viral intrusion of defense against bacterial.Zinc deficiency can make atrophy of thymus gland, and the thymus secretion reduces the weight saving of spleen etc.The T cell quantity reduces, and antibody production descends, lymphocytophthisis, and the neutrophilic granulocyte chemotactic is suppressed, thereby causes resistance to descend, and immunologic function goes down.

In addition, zinc also has the promotion growth promoter, promotes diet, functions such as slow down aging.

In sum: this product has strengthening the spleen and stomach, digestion promoting, benefiting qi and nourishing blood, promotion protein synthesis, supplies with body nutrition, regulates body function, prevents and treats subhealth state, enhancing immunity, antiviral, slow down aging, looks improving and the skin nourishing, locate slow climacteric, improve sleep, resisting fatigue, the infringement of attenuating chemicotherapy, promote wound healing, the best-of-breed functionality nutritional supplement of performing the operation, recover.

Six, processing technology:

1, plant material mixes pulverizing: the plant material in will filling a prescription earlier mixes pulverizing and is corase meal.

2, lixiviate filtrating: the raw material after will pulverizing add (1: water logging bubble 6-10) boiled to cross in lixiviate 1-3 hour and filtered filtrating one in 2 hours, filtering residue add (1: water boil lixiviate 5-8) crossed in 1-2 hour filter two, twice filtratings of filtrating mix the plant material extracting solution.

3, allotment mixes: the aminoacid in will fill a prescription and other raw materials mix with plant extraction liquid and dissolve, and stir.

4, filter: the mixed liquor that stirs is sent into filter filter.

5, filling and capping: filtrate filtered is sent into filling machine fill and capping.

6, antibacterial:, added in the 80-100 ℃ of water antibacterial 20 minutes with the product behind the filling and capping.

7, test package: the product with after the antibacterial, be up to the standards, packing becomes formal product.

It is in order to extract the operation of composition in the raw material fully that blends of plant materials is pulverized.Lixiviate is in pulverizing raw material, to add the operation that a certain proportion of water boil extracts composition in the raw material.Allotment mix be with the amino acid starting material in the prescription dissolve with plant extraction liquid in, and the operation that stirs.Filtering operation is in order to filter out the operation of impurity in the mixed liquor.Fill is to send into filling machine to filtrate filtered, pours into the operation of capping in the bottle.Antibacterial is for killing the operation of harmful microorganism and other harmful components in the product.Test package is qualified to the examination and test of products, and packing becomes formal product.

Seven, quality standard:

1, physical and chemical index

2, be suitable for the crowd: be adapted to the each age group men and women, old and young.

3, instructions of taking: every day 1-2 time, each 100ml.

Eight, the specific embodiment

Embodiment: get 2 kilograms of Cordycepses; 5 kilograms of Fructus Lycii; 6 kilograms in Fructus Hordei Germinatus, 5 kilograms of Fructus Crataegis, 3 kilograms of Pericarpium Citri Reticulataes; Mix to pulverize and be corase meal; Add in the water of (1: 8) and soaked 2 hours, boil lixiviate and crossed in 2 hours and filter filtrating one, the water boil lixiviate that filtering residue adds (1: 5) was crossed and is filtered filtrating two in 1.5 hours; Twice 1.14 kilograms of lysines of filtrating mixing adding, 1.2 kilograms of phenylalanine+tyrosine, 0.96 kilogram of methionine+cystine, 0.96 kilogram of isoleucine, 1.2 kilograms of threonine, 0.24 kilogram of tryptophan, 0.84 kilogram of valine, 0.5 kilogram of theanine, 0.75 kilogram of GABA, 0.4 kilogram of glycine, 0.5 kilogram of alanine, 0.75 kilogram of cysteine, 0.4 kilogram of glutamine, 0.5 kilogram of aspartic acid, 0.4 kilogram of histidine, 0.6 kilogram of glutathion, 0.5 kilogram of carnosine, 1.2 kilograms of sheep placental extract, 1 kilogram of beta glucan, 1 kilogram of yeast rich in selenium, zinc 15 grams dissolve; Stir, send into filter and filter, the mixed liquor after filtering is sent into filling machine fill and capping; Antibacterial is 20 minutes in 90 ℃ of water, and the packing that is up to the standards becomes formal product.

Claims (1)

1. a Chinese caterpillar fungus polypeptide amino-acid nutrition liquid processing technology is characterized by 2 kilograms of Cordycepses, 5 kilograms of Fructus Lycii, 6 kilograms in Fructus Jujubae, 6 kilograms in Fructus Hordei Germinatus, 5 kilograms of Fructus Crataegis, 3 kilograms of Pericarpium Citri Reticulataes, 1.14 kilograms of lysines, 1.20 kilograms of phenylalanine+tyrosine, 0.96 kilogram of methionine+cystine, 1.56 kilograms of leucines, 1.08 kilograms of isoleucine, 1.20 kilograms of threonine, 0.24 kilogram of tryptophan, 0.8 kilogram of valine, 1 kilogram of arginine, 0.6 kilogram of proline, 0.5 kilogram in glutamic acid, 0.5 kilogram of theanine, 0.75 kilogram of GABA, 0.4 kilogram of glycine, 0.5 kilogram of alanine, 0.75 kilogram of cysteine, 0.4 kilogram of glutamine, 0.5 kilogram of aspartic acid, 0.4 kilogram of histidine, 0.6 kilogram of glutathion, 0.5 kilogram of carnosine, 1.2 kilograms of sheep placental extract, 1 kilogram of beta glucan, 1 kilogram of yeast rich in selenium, zinc 15 grams.Through being mixed, pulverizes plant material, twice boiling water lixiviate, and mixing adding aminoacid, zinc dissolve, agitation and filtration, and filling and capping, antibacterial, check, packing become formal product.